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China Particuology 2006年第5期4卷 243-249页

作者： terry a.ring Department of Chemical Engineering University of Utah Salt Lake City UT 84112Fluent Inc. 10 Cavendish Court Lebanon NH 03766

For many processes of industrial significance, due to the strong coupling between particle interactions and fluid dynamics, the population balance must be solved as part of a computational fluid dynamics （CFD） simulation. In this work, a CFD based population balance model is tested using a batch crystallization reactor. In this CFD model, the population balance is solved by the standard method of moments （SMOM） and the quadrature method of moments （QMOM）. The results of these simulations are compared to analytical solutions for the population balance in a batch tank where 1） nucleation, 2） growth, 3） aggregation, and 4） breakage are taking place separately. The results of these comparisons show that the first 6 moments of the population balance are accurately predicted for nucleation, growth, aggregation and breakage at all times.

关键词： population balance computational fluid dynamics particle process modeling

Carnobacteria in fish

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Aquaculture and Fisheries 2024年第2期9卷 193-205页

作者： Einar ring Norwegian College of Fishery Science Faculty of BioscienceFisheries and EconomicsUiT The Arctic University of NorwayTromsø9010Norway

Carnobacterium is a genus of Gram-positive bacteria,within family Carnobacteriaceae,and they are catalase-and oxidase-negative,non-sporing bacteria with properties such as CO_(2)and L(+)-lactic acid production from glucose,but they are not able to grow on acetate *** are ubiquitous lactic acid bacteria and have been isolated from both cold and temperate environments,and they are identified as components of the microbiota in the gastrointestinal(GI)tract of salmonids and several other fish species of which Carnobacterium(piscicola)maltaromaticum,Carnobacterium mobile,Carnobacterium divergens,Carnobacterium alterfunitum,and Carnobacterium inhibens are *** the last two decades several studies have revealed that carnobacteria can act as probiotics to promote health benefits of fish,as well as they in ex vivo studies to some extent can out-compete *** addition to beneficial effects,information is available that some carnobacteria species causing fish *** aim of the present review is to present an updated overview of Carnobacterium in fish,with focus on their presence in the GI tract,their use as probiotic supplement and general information on pathogenic carnobacteria.

关键词： Carnobacterium Gastrointestinal tract Probiotics Fish health Pathogenic

the future of PARTICUOLOGY

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China Particuology 2003年第1期1卷 2-6页

作者： Arthur M. Squires Kui Wang John F.Davidson Qingru Chen John R.Grace Kefa Cen terry a.ring Guilin Yang George E. Klinzing Member U. S. National Academy of Engineering Fellow American Academy of Arts & Sciences University Distinguished Professor (emeritus) Virginia Polytechnic Institute & State University Member Chinese Academy of Sciences Department of Chemical Biology School of Pharmaceutical Sciences Peking University Shell Professor of Chemical Engineering Cambridage University Member Chinese Academy of Engineering China University of Mining and Technology Professor of Chemical Engineering University of British Columbia Member Chinese Academy of Engineering College of Mechanical & Energy Engineering Zhejiang University Professor and Chairman of Chem.& Fuels Eng.Professor of Maer.Sci.& Eng.University of Utah Professor CAS Institute of Coal Chemistry W.K. Whiteford Professor & Vice Provost for Res.University of Pittsburgh

I congratulate the Chinese Society of Particuology(and especially my friend Professor Mooson Kwauk,the Society’s distinguished President Emeritus) forits initiative in launching a new journal devoted to studiesof par... 详细信息

关键词： of in or is as PA In the future of PARTICUOLOGY that

Restimate:Recovery Estimation Tool for Resilience Planning

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Journal of Safety Science and Resilience 2024年第1期5卷 47-63页

作者： Scott Miles Megan Ly Nick terry Youngjun Choe Department of Human Centered Design&Engineering Campus Box 352315University of WashingtonSeattleWA 98195United States of America Department of Industrial&Systems Engineering Box 352650University of WashingtonSeattleWA 98195United States of America

The *** Institute of Standards and Technology(NIST)published the Community Resilience Planning Guide in *** NIST Guide advocates for a participatory process for developing a performance measurement framework for the jurisdiction’s resilience against a scenario *** framework centers around tables of expected and desired recovery times for selected community assets,such as electricity,water,and natural gas *** NIST Guide does not provide a method for estimating the expected recovery ***,building high-fidelity computer models for such estimations requires substantial resources that even larger ju-risdictions cannot *** most promising approach to recovery time estimation is to systematically use data elicited from people to tap into the wisdom of the(knowledgeable)*** paper describes a novel research-through-design project to enable the computer-supported elicitation of recovery time series *** work is the first in the literature to examine people’s ability to estimate recovery curves and how design in-fluences such *** main contribution to resilience planning is three-fold:development of a new elicitation tool called Restimate,understanding its potential user base,and providing insights into how it can facilitate resilience *** is the first tool to enable evidence-based expert elicitation in any community with limited resources for resilience *** resilience planning,those who facilitate high-stakes planning activities under large uncertainties(e.g.,mission-critical system design and planning)will benefit from a similar research-through-design process.

关键词： expert elicitation disaster natural hazard infrastructure community resilience restoration user-centered design computer-supported cooperative work

A randomized,controlled,open label non-inferiority trial of intravenous ferric carboxymaltose versus iron sucrose in patients with iron deficiency anemia in China

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Frontiers of Medicine 2024年第1期18卷 98-108页

作者： Jie Jin Zhihua Ran Emanuele Noseda Bernard Roubert Matthieu Marty Anna Mezzacasa Udo Michael Göring The First Affiliated Hospital Zhejiang University College of MedicineHangzhou310058China Renji Hospital Shanghai Jiao Tong University School of MedicineShanghai200025China Vifor Pharma Glattbrugg8152Switzerland

Iron deficiency(ID)and ID anemia(IDA)pose significant public health concerns in *** iron sucrose(IS)treatment is well-established in the country,ferric carboxymaltose(FCM)offers the advantage of higher doses and fewer *** open label,randomized,controlled,non-inferiority trial was conducted at multiple sites in China to compare the outcomes of FCM(maximum of 2 doses,500 or 1000 mg iron)and IS(up to 11 infusions,200 mg iron)treatments in subjects with *** primary endpoint was the achievement of hemoglobin(Hb)response(an increase of⩾2 g/dL from baseline)within 8 weeks,whereas secondary endpoints included changes in Hb,transferrin saturation,and serum ferritin *** the 371 randomized subjects,a similar percentage of subjects treated with FCM and IS achieved Hb-response(FCM 99.4%,IS 98.3%),thereby confirming the non-inferiority of FCM compared with IS(difference 1.12(−2.15,4.71;95%confidence interval(CI))).Furthermore,a significantly higher proportion of FCM-treated subjects achieved early Hb-response at Week 2(FCM 85.2%,IS 73.2%;difference 12.1(3.31,20.65;95%CI)).Additionally,the increase in TSAT and serum ferritin levels from baseline was significantly greater at all time points for FCM-treated *** safety profiles of FCM and IS were comparable,with the exception of transient hypophosphatemia and pyrexia,which are consistent with FCM’s known safety *** conclusion,FCM proves to be an efficacious treatment for IDA,providing faster Hb-response and correction of ID with fewer administrations than IS.

关键词： iron deficiency anemia intravenous iron ferric carboxymaltose iron sucrose Hb response early response

The Pichia pastoris enzyme production platform:From combinatorial library screening to bench-top fermentation on residual cyanobacterial biomass

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Journal of Bioresources and Bioproducts 2024年第1期9卷 43-57页

作者： Korbinian Sinzinger Ulrike Obst Samed Güner Manuel Döring Magdalena Haslbeck Doris Schieder Volker Sieber Chair of Chemistry of Biogenic Resources Campus Straubing for Biotechnology and SustainabilityTechnical University of MunichStraubing 94315Germany Catalysis Research Center Technical University of MunichGarching 85748Germany SynBiofoundry@TUM Technical University of MunichStraubing 94315Germany School of Chemistry and Molecular Biosciences The University of QueenslandSt.Lucia 4072Australia

The demand for industrial enzymes is continually rising,fueled by the growing need to shift towards more sustainable industrial ***,making efficient enzyme production strains and identifying optimal enzyme expression conditions remains a ***,the production of the enzymes themselves comes with unavoidable impacts,e.g.,the need to utilize secondary ***,we take a more holistic view of bioprocess development and report an integrative approach that allows us to rapidly identify improved enzyme expression and secretion conditions and make use of cyanobacterial waste biomass as feed for supporting Pichia pastoris *** demonstrate these capabilities by producing a phytase secreted by *** that is grown on cyanobacterium hydrolysate and buffered glycerol-complex(BMGY)medium,with genetic expression conditions identified by high-throughput screening of a randomized se-cretion *** our best-performing strain is grown in a fed-batch fermentation on BMGY,we reach over 7000 U/mL in three days.

关键词： Protein secretion Phytase Cyanobacterial biomass Fed-batch fermentation Pichia pastoris

A flexible,thin-film microchannel electrode array device for selective subdiaphragmatic vagus nerve recording

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Microsystems & Nanoengineering 2024年第1期10卷 115-128页

作者： Jongcheon Lim Peter A.Zoss terry L.Powley Hyowon Lee Matthew P.Ward Weldon School of Biomedical Engineering Purdue UniversityWest LafayetteINUSA Birck Nanotechnology Center Purdue UniversityWest LafayetteINUSA Center for Implantable Devices Purdue UniversityWest LafayetteINUSA Department of Psychological Sciences Purdue UniversityWest LafayetteINUSA Purdue Institute of Integrative Neuroscience Purdue UniversityWest LafayetteINUSA Indiana University School of Medicine IndianapolisINUSA

The vagus nerve(VN)plays an important role in regulating physiological conditions in the gastrointestinal(GI)tract by communicating via the parasympathetic pathway to the enteric nervous system(ENS).However,the lack of knowledge in the neurophysiology of the VN and GI tract limits the development of advanced treatments for autonomic dysfunctions related to the *** better understand the complicated underlying mechanisms of the VN-GI tract neurophysiology,it is necessary to use an advanced device enabled by microfabrication *** several candidates including intraneural probe array and extraneural cuff electrodes,microchannel electrode array devices can be used to interface with smaller numbers of nerve fibers by securing them in the separate channel *** microchannel electrode array devices to interface teased nerve structures are relatively bulky with thickness around 200µ*** thick design can potentially harm the delicate tissue structures,including the nerve *** this paper,we present a flexible thin film based microchannel electrode array device(thickness:11.5µm)that can interface with one of the subdiaphragmatic nerve branches of the VN in a *** demonstrated recording evoked compound action potentials(ECAP)from a transected nerve ending that has multiple nerve ***,our analysis confirmed that the signals are from C-fibers that are critical in regulating autonomic neurophysiology in the GI tract.

关键词： electrode recording film

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核物质中张量力效应的相对论第一性原理研究

Science Bulletin 2024年第14期69卷 2166-2169页

作者：王锶博童辉王宸璨赵强 Peter ring 孟杰 Department of Physics and Chongqing Key Laboratory for Strongly Coupled Physics Chongqing UniversityChongqing 401331China Helmholtz Institute for Radiation and Nuclear Physics University of BonnBonn D-53115Germany School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China Center for Exotic Nuclear Studies Institute for Basic ScienceDaejeon 34126South Korea Department of Physics Technical University of MunichGarching D-85747Germany State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

As a crucial ingredient of the nucleon-nucleon(NN)interaction,the tensor force has an important impact on the structural and dynamical properties of the nuclear many-body system,particularly the properties of exotic nuclei far away from the stability,which are crucial for understanding the nucleosynthesis in nuclear *** efforts have been devoted to studying the influence of the tensor force in the effective NN interaction in the nuclear medium within the configuration interaction shell model[1]and the density functional theories(DFTs)[2].Due to the difference of modeling the effective NN interaction and the difficulty of determining the tensor-force strengths in finite nuclei,the tensorforce effects in nuclear physics still need to be fully settled.

关键词：张量力核物质 tensor

Upsilon Constants and Their Usefulness in Planck Scale Quantum Cosmology

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Journal of Modern Physics 2024年第2期15卷 167-173页

作者： Eugene terry Tatum Independent Researcher Bowling Green Kentucky USA

This paper introduces the two Upsilon constants to the reader. Their usefulness is described with respect to acting as coupling constants between the CMB temperature and the Hubble constant. In addition, this paper summarizes the current state of quantum cosmology with respect to the Flat Space Cosmology (FSC) model. Although the FSC quantum cosmology formulae were published in 2018, they are only rearrangements and substitutions of the other assumptions into the original FSC Hubble temperature formula. In a real sense, this temperature formula was the first quantum cosmology formula developed since Hawking’s black hole temperature formula. A recent development in the last month proves that the FSC Hubble temperature formula can be derived from the Stephan-Boltzmann law. Thus, this Hubble temperature formula effectively unites some quantum developments with the general relativity model inherent in FSC. More progress towards unification in the near-future is expected.

关键词： Quantum Cosmology Hubble Constant Planck Scale Upsilon Constant Flat Space Cosmology Black Holes CMB Temperature ΛCDM Cosmology Quantum Gravity Unification

A Solution to the Cosmological Constant Problem Using the Holographic Principle (A Brief Note)

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Journal of Modern Physics 2024年第2期15卷 159-166页

作者： Eugene terry Tatum Independent Researcher Bowling Green Kentucky USA

This paper integrates a quantum conception of the Planck epoch early universe with FSC model formulae and the holographic principle, to offer a reasonable explanation and solution of the cosmological constant problem. Such a solution does not appear to be achievable in cosmological models which do not integrate black hole formulae with quantum formulae such as the Stephan-Boltzmann law. As demonstrated herein, assuming a constant value of Lambda over the great span of cosmic time appears to have been a mistake. It appears that Einstein’s assumption of a constant, in terms of vacuum energy density, was not only a mistake for a statically-balanced universe, but also a mistake for a dynamically-expanding universe.

关键词： Quantum Cosmology Planck Scale Cosmological Constant Black Holes Holographic Principle Flat Space Cosmology AdS-CFT ER = EPR Cosmology Model