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Preventive health measures in inflammatory bowel disease

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World Journal of Gastroenterology 2016年第34期22卷 7625-7644页

作者： Ayokunle T Abegunde Bashir H Muhammad tauseef ali Section of Digestive Diseases and Nutrition Department of MedicineOklahoma University Health Sciences Center Department of Medicine Oklahoma University Health Sciences Center

We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease(IBD). Structured searches were performed in Pub Med,MEDLINE,EMBASE,Web of Science and Cochrane Library from January 1976 to June 2016 using the following keywords:(inflammatory bowel disease OR Crohn's disease OR ulcerative colitis) AND(health maintenance OR preventive health OR health promotion). Abstracts of the articles selected from each of these multiple searches were reviewed,and those meeting the inclusion criteria(that is,providing data regarding preventive health or health maintenance in IBD patients) were recorded. Reference lists from the selected articles were manually reviewed to identify further relevant studies. Patients with IBD are at increased risk of developing adverse events related to the disease course,therapeutic interventions,or non-adherence to medication. Recent studies have suggested that IBD patients do not receive preventive services with the same thoroughness as patients with other chronic diseases. Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians(PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care.

关键词： Health maintenance Prevention Ulcerative colitis Crohn’s disease

Environmental risk factors for inflammatory bowel diseases: Evidence based literature review

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World Journal of Gastroenterology 2016年第27期22卷 6296-6317页

作者： Ayokunle T Abegunde Bashir H Muhammad Owais Bhatti tauseef ali Section of Digestive Diseases and Nutrition Department of Medicine Oklahoma University Health Sciences Center Department of Medicine Oklahoma University Health Sciences Center

AIM: To advances in genetics and immunology have contributed to the current understanding of the pathogenesis of inflammatory bowel diseases(IBD). METHODS: The current opinion on the pathogenesis of IBD suggests that genetically susceptible individuals develop intolerance to dysregulated gut microflora(dysbiosis) and chronic inflammation develops as a result of environmental insults. Environmental exposures are innumerable with varying effects during the life course of individuals with IBD. Studying the relationship between environmental factors and IBD may provide the missing link to increasing our understanding of the etiology and increased incidence of IBD in recent years with implications for prevention, diagnosis, and treatment. Environmental factors are heterogeneous and genetic predisposition, immune dysregulation, or dysbiosis do not lead to the development of IBD in isolation. RESULTS: Current challenges in the study of environmental factors and IBD are how to effectively translate promising results from experimental studies to humans in order to develop models that incorporate the complex interactions between the environment, genetics, immunology, and gut microbiota, and limited high quality interventional studies assessing the effect of modifying environmental factors on the natural history and patient outcomes in ***: This article critically reviews the current evidence on environmental risk factors for IBD and proposes directions for future research.

关键词： Environmental factors Inflammatory bowel disease Exposomes

Updates in vaccination:Recommendations for adult inflammatory bowel disease patients

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World Journal of Gastroenterology 2015年第11期21卷 3184-3196页

作者： Khadija Chaudrey Michelle Salvaggio Aftab Ahmed Sultan Mahmood tauseef ali Department of Medicine Section of GastroenterologyOklahoma University Health Sciences Center Department of Medicine Section of Infectious DiseasesOklahoma University Health Sciences Center Department of Internal Medicine Oklahoma University Health Sciences Center Inflammatory Bowel Disease Center Oklahoma University Physicians

Treatment regimens for inflammatory bowel disease(IBD) incorporate the use of a variety of immunosuppressive agents that increase the risk of *** of many of these infections can be achieved by the timely and judicious use of *** patients tend to be *** of the contributing factors are lack of awareness regarding the significance of vaccinating IBD patients,misperception about safety of vaccinations in immunocompromised patients,ambiguity about the perceived role of the gastroenterologist in contrast to the primary care physician and unavailability of vaccination guidelines focused on IBD *** general,immunocompetent IBD patients can be vaccinated using standard vaccination *** there are special considerations for IBD patients receiving immunosuppressive therapy,IBD travelers and pregnant women with *** review discusses current vaccination recommendations with updates for adult IBD *** for Disease Control and Prevention 2013 vaccination guidelines with 2014 updates and the Advisory Committee on Immunization Practices recommendations have been highlighted as a primary source of recommendations.

关键词： Inflammatory bowel disease Vaccination Immunocompr

Sleep,immunity and inflammation in gastrointestinal disorders

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World Journal of Gastroenterology 2013年第48期19卷 9231-9239页

作者： tauseef ali James Choe Ahmed Awab Theodore L Wagener William C Orr Inflammatory Bowel Disease Center University of Oklahoma Health Sciences Center Oklahoma City OK 73104 United States Department of Medicine University of Oklahoma Health Science Center Oklahoma City OK 73104 United States Department of Medicine Section of Pulmonary and Critical Care Oklahoma City OK 73104 United States Department of Pediatrics University of Oklahoma Health Sciences Center Oklahoma City OK 73104 United States Lynn Health Science Institute Oklahoma City OK 73112 United States

Sleep disorders have become a global issue,and discovering their causes and consequences are the focus of many research *** estimated 70 million Americans suffer from some form of sleep *** sleep disorders have been shown to cause neurocognitive impairment such as decreased cognitive ability,slower response times and performance *** research suggests that individuals with sleep abnormalities are also at greater risk of serious adverse health,economic consequences,and most importantly increased all-cause *** research studies support the associations among sleep,immune function and ***,we review the current research linking sleep,immune function,and gastrointestinal diseases and discuss the interdependent relationship between sleep and these gastrointestinal *** physiologic processes including immune system and inflammatory cytokines help regulate the *** inflammatory cytokines such as tumor necrosis factor,interleukin-1(IL-1),and IL-6 have been shown to be a significant contributor of sleep *** the other hand,sleep disturbances such as sleep deprivation have been shown to up regulate these inflammatory *** in these cytokine levels have been demonstrated in certain gastrointestinal diseases such as inflammatory bowel disease,gastro-esophageal reflux,liver disorders and colorectal *** turn,abnormal sleep brought on by these diseases is shown to contribute to the severity of these same gastrointestinal *** of these relationships will allow gastroenterologists a great opportunity to enhance the care of their patients.

关键词： Sleep Immune function Immunity Irritable bowel syndrome Inflammatory bowel disease Gastroesophageal reflux disease Liver disorders Colon cancer Circadian rhythm

Iron deficiency anemia in inflammatory bowel disease

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World Journal of Gastrointestinal Pathophysiology 2015年第3期6卷 62-72页

作者： Sindhu Kaitha Muhammad Bashir tauseef ali Department of Medicine Section of GastroenterologyOklahoma University Health Sciences Center Department of Internal Medicine Oklahoma University Health Sciences Center

Anemia is a common extraintestinal manifestation of inflammatory bowel disease(IBD) and is frequently overlooked as a complication. Patients with IBD are commonly found to have iron deficiency anemia(IDA) secondary to chronic blood loss, and impaired iron absorption due to tissue inflammation. Patients with iron deficiency may not always manifest with signs and symptoms; so, hemoglobin levels in patients with IBD must be regularly monitored for earlier detection of anemia. IDA in IBD is associated with poor quality of life, necessitating prompt diagnosis and appropriate treatment. IDA is often associated with inflammation in patients with IBD. Thus, commonly used labora-tory parameters are inadequate to diagnose IDA, and newer iron indices, such as reticulocyte hemoglobin content or percentage of hypochromic red cells or zinc protoporphyrin, are required to differentiate IDA from anemia of chronic disease. Oral iron preparations are available and are used in patients with mild disease activity. These preparations are inexpensive and con-venient, but can produce gastrointestinal side effects, such as abdominal pain and diarrhea, that limit their use and patient compliance. These preparations are partly absorbed due to inflammation. Non-absorbed iron can be toxic and worsen IBD disease activity. Although cost-effective intravenous iron formulations are widely available and have improved safety profiles, physicians are reluctant to use them. We present a review of the pathophysiologic mechanisms of IDA in IBD, improved diagnostic and therapeutic strategies, efficacy, and safety of iron replacement in IBD.

关键词： Iron deficiency anemia Inflammatory bowel disease Hepcidin Ferritin Oral iron Intravenous iron

Occult Hepatitis B Flare-up after Chemotherapy Treatment in HBsAg Negative Patient

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International Journal of Clinical Medicine 2011年第5期2卷 621-623页

作者： Shoaib Ahmad Vu Le tauseef ali 不详

Reactivation of Hepatitis B virus causing liver damage is a concern in patients with chronic HBV infections who receive immunosuppressive or cytotoxic treatments. HBV screening should be considered for all patients going to receive immunosuppressive regimens which have the potential to induce reactivation of HBV infection. We discuss here a case of occult Hepatitis B flare after chemotherapy in a patient who had negative acute hepatitis profile including HBsAg prior to therapy and baseline serum AST, ALT, INR, albumin, bilirubin and serum creatinine were within normal limits.

关键词： Hepatitis B Chemotherapy Reactivation

Comparative analysis of CO_(2)emissions and economic performance in the United States and China:Navigating sustainable development in the climate change era

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Geoscience Frontiers 2024年第5期15卷 239-255页

作者： Khalid Mehmood Syed tauseef Hassan Xuchun Qiu Shahid ali Institute of Environmental Health and Ecological Security School of the Environment and Safety EngineeringJiangsu UniversityZhenjiangJiangsu 212013China Department of Trade and Finance Faculty of Economics and ManagementCzech University of Life Sciences PragueKamycka 129PrahaZIP 16500Czechia School of Economics and Management Anhui Polytechnic UniversityWuhu 241000China Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment Suzhou University of Science and TechnologySuzhou 215009China

Economic growth has brought a global climate change into the spotlight,and CO_(2)emissions demonstrate significant challenges in reducing environmental shifts ***,the United States and China contribute the largest amount of CO_(2)*** purpose of this study is to examine the relationship between different types of CO_(2)emissions and economic growth by using a modeling *** analyze total CO_(2)emissions,coal CO_(2)emissions,oil CO_(2)emissions,the global share of coal CO_(2)emissions,the global share of oil CO_(2)emissions,and economic *** study provides unique insights into how to simultaneously reduce CO_(2)emissions and sustain economic growth.A bootstrap autoregressive distributed lag(BARDL)simulation method is utilized to examine the long-and short-run effects of predictors on CO_(2)*** CO_(2)emissions are found to have a significant positive effect on economic growth in the short run but a negative impact on economic growth over the long run in the United *** United States needs to implement stronger measures to balance coal CO_(2)emissions with economic growth for sustainable *** contrast,oil CO_(2)emissions have positive effect for China in both the long run and short ***,China can continue to reduce CO_(2)emissions from oil while maintaining positive economic *** China’s policies promoting cleaner energy alternatives can be adapted and implemented to maintain a balance between economic growth and carbon *** study has valuable insights for policymakers seeking to balance economic growth with carbon reduction *** emphasizes the need to better understand the complex relationship between CO_(2)emissions and economic growth.

关键词： CO_(2)emission Sustainable development Climate change United States China BARDL

A novel (G'/G)-expansion method and its application to the Boussinesq equation

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Chinese Physics B 2014年第2期23卷 34-43页

作者： Md.Nur Alam Md.ali Akbar Syed tauseef Mohyud-Din Department of Mathematics Pabna University of Science and Technology Department of Applied Mathematics University of Rajshahi Department of Mathematics HITEC UniversityTaxila Cantt

In this article, a novel （G＇/G）-expansion method is proposed to search for the traveling wave solutions of nonlinear evolution equations. We construct abundant traveling wave solutions involving parameters to the Boussinesq equation by means of the suggested method. The performance of the method is reliable and useful, and gives more general exact solutions than the existing methods. The new （G＇/G）-expansion method provides not only more general forms of solutions but also cuspon, peakon, soliton, and periodic waves.

关键词： (G'/G)-expansion method Boussinesq equation solitary wave solutions auxiliary nonlinear ordinary differential equation

On biological population model of fractional order

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International Journal of Biomathematics 2016年第5期9卷 107-119页

作者： Syed tauseef Mohyud-Din Ayyaz ali Bandar Bin-Mohsin Department of Mathematics HITEC University Taxila Pakistan Department of Mathematics College of Sciences King Saud University Riyadh Saudi Arabia

In this paper, we extensively studied a mathematical model of biology. It helps us to understand the dynamical procedure of population changes in biological population model and provides valuable predictions. In this model, we establish a variety of exact solutions. To study the exact solutions, we used a fractional complex transform to convert the particular partial differential equation of fractional order into corresponding partial differential equation and modified exp-function method is implemented to investigate the nonlinear equation. Graphical demonstrations along with the numerical data reinforce the efficacy of the used procedure. The specified idea is very effective, unfailing, well-organized and pragmatic for fractional PDEs and could be protracted to further physical happenings.

关键词： Modified exp-function method biological population model fractional calculus Caputo's fractional derivative.