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Classification of Plant Endogenous States Using Machine Learning-Derived Agricultural Indices

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Plant Phenomics 2023年第3期5卷 474-483页

作者： Sally Shuxian Koh Kapil Dev Javier Jingheng Tan Valerie Xinhui Teo Shuyan Zhang Dinish U.S. Malini olivo Daisuke Urano Temasek Life Sciences Laboratory National University of SingaporeSingaporeSingapore Department of Biological Sciences National University of SingaporeSingaporeSingapore Translational Biophotonics Laboratory Institute of Bioengineering and BioimagingAgency for ScienceTechnology and Research(A*STAR)SingaporeSingapore Institute of Materials Research and Engineering(IMRE) Agency for ScienceTechnology and Research(A*STAR)SingaporeSingapore

Leaf color patterns vary depending on leaf age,pathogen infection,and environmental and nutritional stresses;thus,they are widely used to diagnose plant health statuses in agricultural *** visible-near infrared-shortwave infrared(VIS-NIR-SWIR)sensor measures the leaf color pattern from a wide spectral range with high spectral ***,spectral information has only been employed to understand general plant health statuses(e.g.,vegetation index)or phytopigment contents,rather than pinpointing defects of specific metabolic or signaling pathways in ***,we report feature engineering and machine learning methods that utilize VIS-NIR-SWIR leaf reflectance for robust plant health diagnostics,pinpointing physiological alterations associated with the stress hormone,abscisic acid(ABA).Leaf reflectance spectra of wild-type,ABA2-overexpression,and deficient plants were collected under watered and drought ***-and ABA-associated normalized reflectance indices(NRIs)were screened from all possible pairs of wavelength *** associated NRIs showed only a partial overlap with those related to ABA deficiency,but more NRIs were associated with drought due to additional spectral changes within the NIR wavelength *** support vector machine classifiers built with 20 NRIs predicted treatment or genotype groups with an accuracy greater than those with conventional vegetation *** selected NRIs were independent from leaf water content and chlorophyll content,2 well-characterized physiological changes under *** screening of NRIs,streamlined with the development of simple classifiers,serves as the most efficient means of detecting reflectance bands that are highly relevant to characteristics of interest.

关键词： drought reflectance indices

De novo and recurrence of metabolic dysfunction-associated fatty liver disease after liver transplantation

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World Journal of Hepatology 2021年第12期13卷 1991-2004页

作者： Ma Ai Thanda Han Raquel olivo Catherine J Choi Nikolaos Pyrsopoulos Department of Gastroenterology and Hepatology Rutgers New Jersey Medical SchoolNewarkNJ 07103United States Department of Gastroenterology and Hepatology Rutgers UniversityNew Jersey Medical SchoolNewarkNJ 07103United States Department of Medicine Rutgers New Jersey Medical SchoolNewarkNJ 07101United States

Metabolic dysfunction-associated fatty liver disease(MAFLD)is a new acronym adopted from the consensus of international *** the increasing prevalence of MAFLD in pre-transplant settings,de novo and recurrent graft steatosis/MAFLD are common in post-transplant *** impact of graft steatosis on long-term outcomes is *** current knowledge of incidence rate,risk factors,diagnosis,long-term outcomes,and management of graft steatosis(both de novo and recurrent)is discussed in this review.

关键词： Metabolic dysfunction-associated fatty liver disease Metabolic dysfunctionassociated steatohepatitis De novo Recurrent Graft steatosis Fibrosis Survival

Trends in hospitalization for alcoholic hepatitis from 2011 to 2017:A USA nationwide study

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World Journal of Gastroenterology 2022年第34期28卷 5036-5046页

作者： Ali Wakil Mujtaba Mohamed Zaid Tafesh Mumtaz Niazi Raquel olivo Weiyi Xia Patricia Greenberg Nikolaos Pyrsopoulos Department of Gastroenterology and Hepatology Rutgers New Jersey Medical SchoolNewarkNJ 07103USA Department of Gastroenterology and Hepatology Marshall University HospitalHuntingtonWV 25701USA Department of Biostatistics&Epidemiology Rutgers School of Public HealthPiscatawayNJ 08854USA

BACKGROUND Severe alcoholic hepatitis(AH)is one of the most lethal manifestations of alcoholassociated liver *** light of the increase in alcohol consumption worldwide,the incidence of AH is on the rise,and data examining the trends of AH admission is *** To examine inpatient admission trends secondary to AH,along with their clinical outcomes and epidemiological *** The National Inpatient Sample(NIS)database was utilized,and data from 2011 to 2017 were *** included individuals aged≥21 years who were admitted with a primary or secondary diagnosis of AH using the International Classification of Diseases(ICD)-9 and its correspondent ICD-10 *** not related to alcohol was *** national estimates of inpatient admissions were obtained using sample weights provided by the *** AH-related hospitalization demonstrated a significant increase in the USA from 281506(0.7%of the total admission in 2011)to 324050(0.9%of the total admi-ssion in 2017).The median age was 54 *** most common age group was 45–65 years(range 57.8%–60.7%).The most common race was white(63.2%–66.4%),and patients were predominantly male(69.7%–71.2%).The primary healthcare payers were Medicare(29.4%–30.7%)and Medicaid(21.5%–32.5%).The most common geographical location was the Southern USA(33.6%–34.4%).Most patients were admitted to a tertiary care center(50.2%–62.3%)located in urban *** of AH in this inpatient sample was 5.3%in 2011 and 5.5%in *** most common mortality-associated risk factors were acute renal failure(59.6%–72.1%)and gastrointestinal hemorrhage(17.2%–20.3%).The total charges were noted to range between$25242.62 and$*** The number of AH inpatient hospitalizations significantly increased from 2011 to *** could have a substantial financial impact with increasing healthcare costs and ***-mortality remained the same.

关键词： Alcoholic hepatitis Cirrhosis Fatty liver disease Alcohol abuse

Micro-and nano-fiber probes for optical sensing,imaging,and stimulation in biomedical applications

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Photonics Research 2020年第11期8卷 1703-1724页

作者： Xia Yu Shuyan Zhang Malini olivo Nanxi Li School of Instrumentation and Optoelectronic Engineering Beihang UniversityBeijing 100083China Singapore Bioimaging Consortium Agency for ScienceTechnologyand Research(A*STAR)Singapore 138667Singapore Institute of Microelectronics Agency for ScienceTechnologyand Research(A*STAR)Singapore 138634Singapore

The flexibile nature of optical fiber enables it to offer remote-access capabilities,which could be used in many biomedical *** review focuses on different micro-and nano-structured fiber probes for applications in biosensing,imaging,and *** modifications to fiber could extend design freedom from waveguide optimization to functional material *** probes with optimized waveguide structures or integrated functional materials could achieve enhanced optical mode interaction with biosamples,and hence obtain ultrasensitive biosensors with a remarkably low limit of ***,bioimaging with a high spatial resolution can be obtained by engineering dispersion and nonlinearity of light propagation in the fiber core or designing a metal-coated tapered fiber tip with a sub-wavelength *** metasurfaces can be assembled on a fiber tip to achieve a large depth of focus and remove *** is also a compact solution to realize the precise delivery of light for in vivo applications,such as deep brain *** optical beam size,shape,and direction could be steered by the probe ***-and nano-technologies integrated with fiber contribute to various approaches to further improve detection limit,sensitivity,optical resolution,imaging depth,and stimulation precision.

关键词： fiber waveguide stimulation

Data Compression for Next Generation Phasor Data Concentrators (PDCs) in a Smart Grid

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Journal of Information Security 2016年第5期7卷 291-296页

作者： Erwan olivo Mitch Campion Prakash Ranganathan Department of Electrical Engineering University of North Dakota Grand Forks ND USA

The storage space and cost for Smart Grid datasets has been growing exponentially due to its high data-rate of various sensor readings from Automated Metering Infrastructure (AMI), and Phasor Measurement Units (PMUs). The paper focuses on Phasor Data Concentrators (PDCs) that aggregate data from PMUs. PMUs measure real-time voltage, current and frequency parameters across the electrical grid. A typical PDC can process data from anywhere ten to forty PMUs. The paper exploits the need for appropriate security and data compression challenges simultaneously. As a result, an optimal compression method ER1c is investigated for efficient storage of IREG and C37.118 timestamped PDC data sets. We expect that our approach can greatly reduce the storage cost requirements of commercial available PDCs (SEL 3373, GE Multilin P30) by 80%. For example, 2 years of PDC data storage space can be easily replaced with only 10 days of storage space. In addition, our approach in combination with AES 256 encryption can protect PDC data to larger degree as per National Institute of Standards and Technology (NIST) standards.

关键词： Compression PDCs Data Security Smart Metering Smart Grid

Semaglutide’s Trail of Success in Weight Loss Management and HbA1c Reduction: A Systematic Review

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Health 2023年第10期15卷 1070-1083页

作者： Shayne Q. Paff Mariam Sahibzada Jacqueline olivo olivo Medical and Wellness Centers Chicago Illinois USA Universidad Autonoma de Guadalajara Jalisco Mexico School of Public Health Baylor University Waco Texas USA Ayub Medical College Abbottabad Pakistan Royal College of Surgeons in Ireland Dublin Ireland Universidad San Luis Gonzaga Ica Peru University of Illinois Chicago Illinois USA Masonic Advocate Illinois Hospital Chicago Illinois USA Saint Francis Hospital Evanston Illinois USA

Introduction: Obesity is a preventable health condition, yet it remains a complex relapsing global health conundrum, triggering an array of comorbidities, including diabetes, dyslipidemia, hypertension, and mental health decline. This review intends to highlight the success of semaglutide for its therapeutic intervention for weight loss management in diabetics and non-diabetics and HbA1c reduction in type 2 diabetics. Methods: We searched and systematically reviewed the literature from within the past ten years on semaglutide utilization for weight loss and HbA1c reduction. Databases investigated included PMC, JAMA, Nature Medicine, and The Lancet, resulting in four original research articles that were systematically reviewed. Web consultations with WHO, CDC, and Healthy People 2030 were conducted to ascertain epidemiological obesity and diabetes data. AAFP and USPSTF references were included for obesity management and preventive care guidelines. Results: Based on results from systematically reviewing four original research studies, semaglutide can effectively reduce elevated weight and HbA1c, using the once-weekly subcutaneous injection formulation. A composite average percent weight loss of 8.27% (16 - 20 pounds) and an average HbA1c percent reduction rate of 1.07% (3 - 4 points) were attained. There were no major adverse events reported from any of the four original research studies related to the drug. Discussion: With evidence from several studies after its FDA approval, semaglutide delivers a promise for weight loss management and HbA1c reduction for appropriate patient populations. Clinician and patient education on its proper use should be continuously revisited.

关键词： Preventive Care Obesity Management Diabetes Management Chronic Disease Adjunct Therapy Weight Loss Management

Toxic anterior segment syndrome after implantation of phakic implantable collamer lens

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International Journal of Ophthalmology(English edition) 2019年第1期12卷 175-177页

作者： Erick Hernandez-Bogantes Arturo Ramirez-Miranda Andrew olivo-Payne Alexandra Abdala-Figuerola Alejandro Navas Enrique O.Graue-Hernandez Department of Cornea and Refractive Surgery Conde of Valenciana Foundation Institute of Ophthalmology Ocular Center Department of Cornea and Refractive Surgery Atlantic Laser Unit Center

Dear Editor,Iam *** Hemandez-Bogantes from the Department of Cornea and Refractive Surgery,Conde of Valenciana Foundation Institute of Ophthalmology,Mexico City,Mexico. The purpose of this letter is to present 3 cases (6 eyes)of toxic anterior segment syndrome (TASS)after same day implantation of a posterior phakic implantable collamer lens (ICL;V4c Visian ICL;STAAR Surgical,Monrovia,CA,USA).

关键词： Iam Dr.Erick Hemandez-Bogantes Valenciana Foundation implantation

Theoretical Application to Understand Food Insecurity Among College Students: A Multi-Systems Life Course Perspective

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Sociology Study 2019年第2期9卷 75-83页

作者： Tracey Marie Barnett Reina olivo Valandra Kameri Christy University of Arkansas FayettevilleUSA

Empirical studies have shown a distinct relationship between academic performance and food insecurity in college students. Specifically, food-insecure students are more likely to report a lower grade point average than their food secure counterparts. Since the Great Recession, more attention has been given to the topic of hunger and food insecurity among college students;however, the literature still lacks a comprehensive examination of various issues facing today’s college students. Using a multi-systems life course (MSLC) perspective, this paper provides a conceptual explanation of the lived experience of college students by offering a better understanding of the unique challenges faced by this population. Findings from this study will assist researchers, practitioners, and university administrators in their efforts to address hunger among this population.

关键词： multi-systems life course perspective hunger food insecurity college students university

A Case Report of Alloimmune Hepatitis after Direct-acting Antiviral Treatment in a Liver Transplant Patient

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Journal of Clinical and Translational Hepatology 2020年第4期8卷 459-462页

作者： Catherine Choi Youssef Botros Jamil Shah Pei Xue Anja Jones Mark Galan Raquel olivo Mumtaz Niazi Flavio Paterno James Guarrera Nikolaos T.Pyrsopoulos Department of Internal Medicine Rutgers New Jersey Medical SchoolNewarkNJUSA Division of Gastroenterology St.Joseph’s University Medical CenterPatersonNJUSA Division of Gastroenterology&Hepatology The Brooklyn Hospital CenterBrooklynNYUSA Rutgers New Jersey Medical School NewarkNJUSA Department of Pathology Immunology&Laboratory MedicineRutgers New Jersey Medical SchoolNewarkNJUSA Division of Gastroenterology&Hepatology Department of MedicineRutgers New Jersey Medical SchoolNewarkNJUSA Division of Liver Transplantation&Hepatobiliary Surgery Department of SurgeryRutgers New Jersey Medical SchoolNewarkNJUSA

Direct-acting antiviral (DAA) therapy is often well-tolerated, and adverse events from DAA therapy are uncommon. We report a case of a woman who underwent orthotopic liver transplant for chronic hepatitis C infection and later devel-oped alloimmune hepatitis shortly after starting DAA therapy for recurrent hepatitis C infection. The patient developed acute alloimmune hepatitis approximately 2 weeks after starting treatment with sofosbuvir, velpatasvir, and voxilap-revir. This case report proposes a dysregulation of immune surveillance due to the DAA stimulation of host immunity and rapid elimination of hepatitis C viral load as a precipitating factor for the alloimmune process, leading to alloimmune hepatitis in a post-transplant patient who starts on DAA.

关键词： Autoimmune hepatitis Hepatitis C Liver transplant