Trends in hospitalization for alcoholic hepatitis from 2011 to 2017:A USA nationwide study

作     者：Ali Wakil Mujtaba Mohamed Zaid Tafesh Mumtaz Niazi Raquel Olivo Weiyi Xia Patricia Greenberg Nikolaos Pyrsopoulos 

作者机构：Department of Gastroenterology and HepatologyRutgers New Jersey Medical SchoolNewarkNJ 07103USA Department of Gastroenterology and HepatologyMarshall University HospitalHuntingtonWV 25701USA Department of Biostatistics&EpidemiologyRutgers School of Public HealthPiscatawayNJ 08854USA 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2022年第28卷第34期

页      面：5036-5046页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：UK Research and Innovation  UKRI  (105305) 

主　　题：Alcoholic hepatitis Cirrhosis Fatty liver disease Alcohol abuse 

摘      要：BACKGROUND Severe alcoholic hepatitis(AH)is one of the most lethal manifestations of alcoholassociated liver *** light of the increase in alcohol consumption worldwide,the incidence of AH is on the rise,and data examining the trends of AH admission is *** To examine inpatient admission trends secondary to AH,along with their clinical outcomes and epidemiological *** The National Inpatient Sample(NIS)database was utilized,and data from 2011 to 2017 were *** included individuals aged≥21 years who were admitted with a primary or secondary diagnosis of AH using the International Classification of Diseases(ICD)-9 and its correspondent ICD-10 *** not related to alcohol was *** national estimates of inpatient admissions were obtained using sample weights provided by the *** AH-related hospitalization demonstrated a significant increase in the USA from 281506(0.7%of the total admission in 2011)to 324050(0.9%of the total admi-ssion in 2017).The median age was 54 *** most common age group was 45–65 years(range 57.8%–60.7%).The most common race was white(63.2%–66.4%),and patients were predominantly male(69.7%–71.2%).The primary healthcare payers were Medicare(29.4%–30.7%)and Medicaid(21.5%–32.5%).The most common geographical location was the Southern USA(33.6%–34.4%).Most patients were admitted to a tertiary care center(50.2%–62.3%)located in urban *** of AH in this inpatient sample was 5.3%in 2011 and 5.5%in *** most common mortality-associated risk factors were acute renal failure(59.6%–72.1%)and gastrointestinal hemorrhage(17.2%–20.3%).The total charges were noted to range between$25242.62 and$*** The number of AH inpatient hospitalizations significantly increased from 2011 to *** could have a substantial financial impact with increasing healthcare costs and ***-mortality remained the same.