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Prognostic relevance of ventricular arrhythmias in surgical patients with gastrointestinal tumors

World Journal of Gastrointestinal Oncology 2024年第5期16卷 1787-1795页

作者： Jiao-Jie Xue Su-Tian Hu Chong-Chong Wang Zhi-Chong Chen Shi-Yao Cheng Shu-Qi Yu Hua-Jing Peng yi-tao zhang Wei-Jie Zeng Department of Cardiovascular Internal Medicine Sun Yat-sen University Sixth Affiliated HospitalGuangzhou 510655Guangdong ProvinceChina Department of Cardiovascular Internal Medicine The Fifth Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510700Guangdong ProvinceChina Department of Ultrasound Fuwai HospitalChinese Academy of Medical Sciences ShenzhenShenzhen 518052Guangdong ProvinceChina Department of Kidney Internal Medicine Sun Yat-sen University First Affiliated HospitalGuangzhou 510062Guangdong ProvinceChina

BACKGROUND Individuals diagnosed with gastrointestinal tumors are at an increased risk of developing cardiovascular *** which,ventricular arrhythmia is a prevalent clinical *** suggests that ventricular arrhythmias may have predictive value in the prognosis of patients with gastrointestinal *** To explore the prognostic value of ventricular arrhythmias in patients with gastrointestinal tumors receiving *** We retrospectively analyzed data from 130 patients undergoing gastrointestinal tumor *** patients were evaluated by a 24-h ambulatory electrocardiogram(ECG)at the Sixth Affiliated Hospital of Sun Yat-sen University from January 2018 to June ***,41 general healthy age-matched and sexmatched controls were *** were categorized into survival and non-survival *** primary endpoint was all-cause mortality,and secondary endpoints included major adverse cardiovascular events(MACEs).RESULTS Colorectal tumors comprised 90%of *** ambulatory ECG monitoring revealed that among the 130 patients with gastrointestinal tumors,100(76.92%)exhibited varying degrees of premature ventricular contractions(PVCs).Ten patients(7.69%)manifested non-sustained ventricular tachycardia(NSVT).The patients with gastrointestinal tumors exhibited higher PVCs compared to the healthy controls on both conventional ECG[27(21.3)vs 1(2.5),P=0.012]and 24-h ambulatory ECG[14(1.0,405)vs 1(0,6.5),P35/24 h to all-cause mortality,and NSVT was associated with ***,neither PVC burden nor NSVT independently predicted outcomes according to multivariate *** Patients with gastrointestinal tumors exhibited elevated ***>35/24 h and NSVT detected by 24-h ambulatory ECG were prognos

关键词： Ventricular arrhythmia Gastrointestinal tumor Major adverse cardiovascular events Prognostic Surgery

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H-bonding template-directed synthesis of a complete m-PDA-bridged ladder polyhydrosiloxane (OLPHS)

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Chinese Chemical Letters 2007年第7期18卷 779-782页

作者： Kui Lin Deng tao yi zhang Xiao Jing zhang Ping Xie Rong Ben zhang State Key Laboratory on Polymer Physics ＆ Chemistry Joint Laboratory of Polymer Science ＆ MaterialsInstitute of Chemistry Chinese Academy of Sciences Beijing 100080 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China College of Chemistry ＆ Environmental Science Hebei University Baoding 071002 China

A highly ordered m-phenylenediimino-bridged ladder polyhydrosiloxane （abbr. OLPHS） with Mn = 1.24 × 10^4 was synthesized stoichiometric hydrolysis and dehydrochlorination condensation reaction between Si-Cl and Si-OH bonds. The complete ladder structure of OLPHS has been confirmed by the following three data. Two characteristic Bragg＇s peaks representing the ladder width （w = 0.94 nm） and ladder thickness （t = 0.42 nm） were observed in XRD analysis, which are consistent with those calculated by molecular simulation. The very sharp absorption with a small half-peak width （w1/2 = 0.5 ppm） for [（-HN）HSiO2/2]n moiety of OLPHS in ^29Si NMR spectrum indicated presence of the complete ladder structure. As collateral evidence, a higher glass transition temperature （Tg = 105 ℃） is also recorded in the DSC measurement, implying the high stiffness of ladder chain of OLPHS.

关键词： H-bonding template Ladder polysiloxane Self-assembly Stepwise coupling/polymerization

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The potential of herbal drugs to treat heart failure:The roles of Sirt1/AMPK

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Journal of Pharmaceutical Analysis 2024年第2期14卷 157-176页

作者： tao zhang Lei Xu Xiaowei Guo Honglin tao Yue Liu Xianfeng Liu yi zhang Xianli Meng State Key Laboratory of Southwestern Chinese Medicine Resources Innovative Institute of Chinese Medicine and PharmacyChengdu University of Traditional Chinese MedicineChengdu611137China College of Pharmacy Chengdu University of Traditional Chinese MedicineChengdu611137China School of Ethnic Medicine Chengdu University of Traditional Chinese MedicineChengdu611137China Meishan Hospital of Chengdu University of Traditional Chinese Medicine MeishanSichuan620032China

Heart failure(HF)is a highly morbid syndrome that seriously affects the physical and mental health of patients and generates an enormous socio-economic *** addition to cardiac myocyte oxidative stress and apoptosis,which are considered mechanisms for the development of HF,alterations in cardiac energy metabolism and pathological autophagy also contribute to cardiac abnormalities and ultimately *** information regulator 1(Sirt1)and adenosine monophosphate-activated protein kinase(AMPK)are nicotinamide adenine dinucleotide(NAD+)-dependent deacetylases and phosphorylated kinases,*** play similar roles in regulating some pathological processes of the heart through regulating targets such as peroxisome proliferator-activated receptorγcoactivator 1α(PGC-1α),protein 38 mitogen-activated protein kinase(p38 MAPK),peroxisome proliferator-activated receptors(PPARs),and mammalian target of rapamycin(mTOR).We summarized the synergistic effects of Sirt1 and AMPK in the heart,and listed the traditional Chinese medicine(TCM)that exhibit cardioprotective properties by modulating the Sirt1/AMPK pathway,to provide a basis for the development of Sirt1/AMPK activators or inhibitors for the treatment of HF and other cardiovascular diseases(CVDs).

关键词： Heart failure Silent information regulator 1 Adenosine monophosphate-activated protein kinase Traditional Chinese medicine

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Localization of q-form fields on a de Sitter brane in chameleon gravity

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Frontiers of physics 2024年第3期19卷 11-18页

作者： yi Zhong tao-tao Sui School of Physics and Electronics Science Hunan UniversityChangsha 410082China Lanzhou Center for Theoretical Physics Key Laboratory of Theoretical Physics of Gansu Provinceand Key Laboratory of Quantum Theory and Applications of MoELanzhou UniversityLanzhou 730000China College of Physics Nanjing University of Aeronautics and AstronauticsNanjing 211106China

Recently,it was found that the vector field can be naturally localized on the thick brane in chameleon *** this work,we extend this study to encompass de Sitter brane *** focus on the localization of q-form *** scalar and vector fields can be localized on the de Sitter brane,while the KR field cannot be *** condition for localization of the scalar and vector fields is ***,we investigate the localization characteristics in two examples with given conformal factor b(ϕ).In the first case,the effective potentials and KK modes of the matter fields are obtained asymmetric even though the de Sitter brane has Z2 *** the second case,volcano-like effective potentials are generated in the de Sitter brane model.

关键词： brane q-form field chameleon gravity

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Wetting alternating with partial drying during grain filling increases lysine biosynthesis in inferior rice grain

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The Crop Journal 2024年第1期12卷 262-270页

作者： yi Jiang Wenli tao Weiyang zhang Zhiqin Wang Jianchang Yang Jiangsu Key Laboratory of Crop Genetics and Physiology/Co-Innovation Center for Modern Production Technology of Grain Crops Yangzhou UniversityYangzhou 225009JiangsuChina

Lysine content is a criterion of the nutritional quality of *** the process of lysine biosynthesis in early-flowering superior grain(SG)and late-flowering inferior grain(IG)of rice would advance breeding and cultivation to improve nutritional ***,little information is available on differences in lysine anabolism between SG and IG and the underlying mechanism,and whether and how irrigation regimes affect lysine anabolism in these grains.A japonica rice cultivar was grown in the field and two irrigation regimes,continuous flooding(CF)and wetting alternating with partial drying(WAPD),were imposed from heading to the mature *** content and activities of key enzymes of lysine biosynthesis,and levels of brassinosteroids(BRs)were lower in the IG than in the SG at the early grainfilling stage but higher at middle and late grain-filling *** increased activities of these key enzymes,BR levels,and contents of lysine and total amino acids in IG,but not SG relative to *** of 2,4-epibrassinolide to rice panicles in CF during early grain filling reproduced the effects of WAPD,but neither treatment altered the activities of enzymes responsible for lysine catabolism in either SG or *** and elevated BR levels during grain filling increased lysine biosynthesis in *** in lysine biosynthesis in rice should focus on IG.

关键词： Brassinosteroids Inferior grain Lysine biosynthesis Rice Wetting alternating with partial drying

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Transparent micropatterned conductive films based on highlyordered nanowire network

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Nano Research 2024年第5期17卷 4288-4297页

作者： Xin-Ran zhang Hai-tao Deng Xu Zeng yi-Lin Wang Peng Huang Xiao-Sheng zhang School of Integrated Circuit Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

Transparent conductive films that are based on nanowire networks are essential to construct flexible,wearable,and even stretchable ***,large-scale precise micropatterning,especially with regard to the controllability of the organizing orientation of nanowires,is a critical ***,we proposed a liquid film rupture self-assembly approach for manufacturing transparent conductive films with microstructure arrays based on a highly ordered nanowire *** large-scale microstructure conductive films were fabricated through air-liquid interface self-assembly and liquid film rupture *** typical micropattern morphologies,including square,hexagon,circle,serpentine,etc.,were prepared to reveal the universal applicability of the proposed *** homogeneity and controllability of this approach were verified for multiple *** the assembly cycles increasing,the optical transmittance decreases *** addition,theoretical model analysis is carried out,and the analytical formula of the speed of the film moving with the surface tension and the density of the liquid film is ***,the feasibility of this approach for piezoresistive strain sensors is *** fabrication approach demonstrated a cost-effective and efficient method for precisely arranging nanowires,which is useful in transparent and wearable applications.

关键词： flexible electronics transparent conductive network micropatterning nanowires micro electromechanical systems(MEMS)

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Trend of Storm Surge Induced by Typical Landfall Super Typhoons During 1975–2021 in the Eastern China Sea

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Journal of Ocean University of China 2024年第2期23卷 277-286页

作者： LUO Feng WANG yi tao Aifeng SHI Jian WANG Yongzhi zhang Chi College of Harbour Coastal and Offshore EngineeringHohai UniversityNanjing 210098China Nantong Ocean and Coastal Engineering Research Institute Hohai UniversityNantong 226000China Key Laboratory of Ministry of Education for Coastal Disaster and Protection Hohai UniversityNanjing 210098China College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073China The First Institute of Oceanography MNRQingdao 266061China

Climate change affects the activity of global and regional tropical cyclones(TCs).Among all TCs,typical super typhoons(STYs)are particularly devastating because they maintain their intensity when landing on the coast and thus cause casualties,economic losses,and environmental *** a 3D tidal model,we reconstructed the typhoon(TY)wind field to simulate the storm surge induced by typical *** TY activity was then analyzed using historical *** showed a downtrend of varying degrees in the annual frequency of STYs and TCs in the Western North Pacific(WNP)Basin,with a significant trend change observed for TCs from 1949 to 2021.A large difference in the interannual change in frequency was found between STYs and TCs in the WNP and Eastern China Sea(ECS).Along the coast of EC,the frequency of landfall TCs showed a weak downtrend,and the typical STYs showed reverse micro growth with peak activity in ***,Fujian,and Taiwan were highly vulnerable to the frontal hits of typical *** by climate change,the average lifetime maximum intensity(LMI)locations and landfall locations of typical STYs in the ECS basin showed a significant poleward migration *** addition,the annual average LMI and accumulated cyclone energy showed an uptrend,indicating the increasing severity of the disaster *** by the typical STY activity in the ECS,the maximum storm surge area also showed poleward migration,and the coast of North China faced potential growth in high storm surge risks.

关键词： storm surge super typhoons tropical cyclones eastern China Sea poleward migration

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An electron-transfer[Fe_(2)Co_(2)]square complex exhibiting unprecedented wide room-temperature hysteresis

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Science China Chemistry 2024年第4期67卷 1198-1207页

作者： Xin-Hua Zhao yi-Fei Deng Jia-tao Chen Jiong Yang Yuan-Zhu zhang Department of Chemistry Southern University of Science and Technology(SUSTech)Shenzhen 518055China

Switchable molecules with magnetic bistability that can function at standard conditions are highly desirable from the perspective of practical *** the last decade,significant progress has been made in modulating thermally induced electrontransfer-coupled spin transition(ETCST)events between diamagnetic{Fe_(LS)^(Ⅱ)(μ-CN)Co_(LS)^(Ⅲ)}and paramagnetic{Fe_(LS)^(Ⅲ)(μ-CN)-Co_(HS)^(Ⅱ)}electron configurations(named LS and HS,respectively,for short)within the Fe/Co mixed-valence cyanometallate ***,we prepared a novel[Fe_(2)Co_(2)]square complex[(pzTp)Fe(CN)_(3)Co(bnbpen)]_(2)[NO_(3)]_(2)·4CH_(3)OH·2.5H_(2)O(1·Solv)and its desolvated phase[(pzTp)Fe(CN)_(3)Co(bnbpen)]_(2)[NO_(3)]_(2)(1),obtained via single-crystal-to-single-crystal(SCSC)*** 1·Solv remaining in the diamagnetic state below room temperature exhibits an irreversible ETCST behavior accompanied by desolvation upon ***,complex 1 displays an unprecedented rate-dependent ETCST behaviour involving with two diamagnetic LS states(a dynamically favoured LS1 state and a thermodynamically favoured LS2state),between which a net one-way transition from LS1 to LS2 is accessible likely via a structural phase transition(SPT)above255 ***,two well separated transition channels(HS?LS1 at around 255 K and HS←→LS2 in the temperature range of 317-350 K)are achieved according to either fast(>20 K/min)or slow rate(<1 K/min),*** a moderate rate of 3 K/min,complex 1 shows a wide hysteresis of 66 K centered at 328 K,the largest yet reported for discrete Fe/Co cyanometallate *** 1 represents the first ETCST example coupled with dynamic SPT,providing a new strategy for manipulating bistability within this fascinating cyanometallate family.

关键词： switchable molecules cyanometallate complexes electron transfer hysteresis structural phase transition

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Progress in enhancing the remediation performance of microbial fuel cells for contaminated groundwater

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Journal of Environmental Sciences 2024年第11期145卷 28-49页

作者： Yuan Liang Dong Yu Hui Ma tao zhang yi Chen Naveed Akbar Shengyan Pu State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdu 610059China State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil&Water Pollution Chengdu University of TechnologyChengdu 610059China

Microbial fuel cells(MFCs)have become more prevalent in groundwater remediation due to their capacity for power generation,removal of pollution,ease of assembly,and low secondary *** is currently being evaluated for practical application in an effort to eliminate groundwater ***,a considerable majority of research was conducted in *** the operational circumstances including anaerobic characteristics,pH,and temperature vary at different *** addition,the complexity of contaminants and the positioning of MFCs significantly affect remediation *** the aforementioned factors into consideration,this reviewsummarizes a bibliography on the application of MFCs for the remediation of groundwater contamination during the last ten decades and assesses the impact of environmental conditions on the treatment *** design of the reactor,including configuration,dimensions,electrodes,membranes,separators,and target contaminants are *** review aims to provide practical guidance for the future application of MFCs in groundwater remediation.

关键词： Microbial fuel cells(MFCs) Contaminated groundwater Groundwater remediation Biodegradation

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Deep Guided Attention Network for Joint Denoising and Demosaicing in Real Image

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Chinese Journal of Electronics 2024年第1期33卷 303-312页

作者： tao zhang ying FU Jun zhang School of Computer Science and Technology Beijing Institute of Technology Advanced Reasearch Institute of Multidisciplinary Science Beijing Institute of Technology

Denoising(DN) and demosaicing(DM) are the first crucial stages in the image signal processing pipeline. Recently, researches pay more attention to solve DN and DM in a joint manner, which is an extremely undetermined inverse problem. Existing deep learning methods learn the desired prior on synthetic dataset, which limits the generalization of learned network to the real world data. Moreover, existing methods mainly focus on the raw data property of high green information sampling rate for DM, but occasionally exploit the high intensity and signalto-noise(SNR) of green channel. In this work, a deep guided attention network(DGAN) is presented for real image joint DN and DM(JDD), which considers both high SNR and high sampling rate of green information for DN and DM, respectively. To ease the training and fully exploit the data property of green channel, we first train DN and DM sub-networks sequentially and then learn them jointly, which can alleviate the error accumulation. Besides, in order to support the real image JDD, we collect paired raw clean RGB and noisy mosaic images to conduct a realistic dataset. The experimental results on real JDD dataset show the presented approach performs better than the state-of-the-art methods, in terms of both quantitative metrics and qualitative visualization.

关键词： Training Visualization Inverse problems Green products Noise reduction Pipelines Signal processing

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