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The effects of aerobic exercise training on oxidant-antioxidant balance, neurotrophic factor levels, and blood-brain barrier function in obese and non-obese men

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Journal of Sport and Health Science 2017年第4期6卷 447-453页

作者： Hee-tae Roh Wi-young So Department of Physical Education College of Arts and Physical Education Dong-A University Busan 604-714 Republic of Korea Sports and Health Care Major College of Humanities and Arts Korea National University of Transportation Chungju-si 380-702 Republic of Korea

Purpose: The purpose of this study was to investigate the effects of obesity and aerobic exercise training on oxidant-antioxidant balance,neurotrophic factor levels, and blood-brain barrier(BBB) ***: Ten non-obese healthy men(body mass index < 25 kg/m2) and 10 obese men(body mass index ≥ 25 kg/m2) were included in the *** groups performed treadmill exercise for 40 min 3 times weekly for 8 weeks at 70% heart rate reserve. Blood samples were collected to examine oxidant-antioxidant balance(reactive oxygen species(ROS) and superoxide dismutase(SOD) activity levels), neurotrophic factors(brain-derived neurotrophic factor(BDNF), nerve growth factor, and glial cell line-derived neurotrophic factor levels), and BBB function(S100βand neuron-specific enolase(NSE) levels) before and after exercise ***: The obese group showed significantly greater changes than the non-obese group in serum ROS(-0.46 ± 0.31 mmol/L vs.-0.10 ±0.17 mmol/L,p=0.005),serum S100 p levels(-8.50 ± 5.92 ng/L vs.-0.78 ± 5.45 ng/L,p=0.007),and serum NSE levels(-0.89 ± 0.54 μg/L vs.-0.01 ± 0.74 μg/L,p= 0.007) after training. At baseline,the obese group showed significantly higher serum ROS and S100β levels and significantly lower serum SOD activity and BDNF levels than the non-obese group(p < 0.05). The obese group showed significantly lower serum ROS, S100β,and NSE levels and significantly higher serum SOD activity and BDNF levels after training compared with baseline(p < 0.05).Conclusion: These results suggest that obesity can reduce serum neurotrophic factor levels and can induce BBB dysfunction. On the other hand,aerobic exercise can improve an oxidant-antioxidant imbalance in obese subjects and limit BBB dysfunction.

关键词： Blood-brain barrier Exercise training Neurotrophic factor Obesity Oxidative stress Redox balance

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Clinical significance of the neutrophil-lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis

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World Journal of Gastroenterology 2017年第21期23卷 3883-3889页

作者： tae Joo Jeon Ji young Park Division of Gastroenterology Department of Internal Medicine Inje University College of Medicine Sanggye Paik Hospital

AIM To investigated the prognostic value of the neutrophillymphocyte ratio(NLR) in patients with acute pancreatitis and determined an optimal cut-off value for the prediction of adverse outcomes in these *** We retrospectively analyzed 490 patients with acute pancreatitis diagnosed between March 2007 and December 2012. NLRs were calculated at admission and 24, 48, and 72 h after admission. Patients were grouped according to acute pancreatitis severity and organ failure occurrence, and a comparative analysis was performed to compare the NLR between groups. RESULTS Among the 490 patients, 70 had severe acute pancreatitis with 31 experiencing organ failure. The severe acute pancreatitis group had a significantly higher NLR than the mild acute pancreatitis group on all 4 d(median, 6.14, 6.71, 5.70, and 4.00 vs 4.74, 4.47, 3.20, and 3.30, respectively, P < 0.05). The organ failure group had a significantly higher NLR than the group without organ failure on all 4 d(median, 7.09, 6.72, 6.27, and 6.24 vs 4.85, 4.49, 3.35, and 2.34, respectively, P < 0.05). The optimal cut-off value for baseline NLR was 4.76 in predicting severity and 4.88in predicting organ failure in acute pancreatitis. CONCLUSION Elevated baseline NLR correlates with severe acute pancreatitis and organ failure.

关键词： Acute pancreatitis Neutrophil-lymphocyte ratio Organ failure Severe acute pancreatitis

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Phosphorus fractionation and release characteristics of sediment in the Saemangeum Reservoir for seasonal change

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International Journal of Sediment Research 2018年第3期33卷 250-261页

作者： Dong-Heui Kwak young-tae Jeon young Duck Hur Jeongeup Industry-Academic Cooperation Support Center Chonbuk National University Jeollabuk-do Provincial Covernment Department of Environmental Engineering Chonbuk National University

Periodical algal blooms result in deposition and release of phosphorus(P) from the sediment into the water. Therefore, during seasonal changes when algal particles begin to settle to the bottom, understanding the behavior and distribution characteristics of the P in sediment is the most important key to manage the water quality of the Saemangeum Reservoir. In this study, the variation of water quality and sediment composition including chlorophyll-a(Chl-a) and P was investigated to determine the interaction between water and sediment. The study focused primarily on algal particle sedimentation that affects the P release and mineralization of sediment. The Chl-a concentration in water showed a sharp decline in October when the algae began to die in the fall, and afterward the concentration of chemical oxygen demand(COD) and total P(TP) in the sediment increased due to the sedimentation of decaying algal particles in *** the same period of time, the readily bio-available P(RAP) in the sediment showed a drastic increase in the upper region where the Chl-a concentration of water was high. In sequence, the high RAP zone shifted from the upper region to the lower region in the early winter. The RAP shift was considered to be derived from the physical flow of the overlying water from which the decomposing algae settled on the surface of the sediment. The Saemangeum Reservoir was constructed recently; therefore, all the types of inorganic P fractions except soluble reactive phosphorus(SRP) that exist on the bottom surface of the lake and the marsh’s sediment layer were not sufficient to significantly influence the overlying water. On the other hand, the released P from the algae was distinct and sensitive to the seasonal change. In conclusion,the algal particle sedimentation was important to control eutrophication rather than P release from the mineralized inorganic P of the sediment surface layer in the Seamangeum Reservoir.

关键词： Algal bloom Fractionation Phosphorus Water management Release Sediment

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Febrile infants:written guidelines to reduce non-essential hospitalizations

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World Journal of Pediatrics 2021年第5期17卷 555-556页

作者： Ji yoon Oh Soo-young Lee Department of Pediatrics Bucheon St.Mary's HospitalCollege of MedicineThe Catholic University of Korea327 Sosa-roWonmi-guBucheon 14647.Republic of Korea

Management of febrile infants,especially those younger than 3 months of age,is of clinical importance due to the relatively high risk of serious bacterial infection(SBI),such as bacterial meningitis,bacteremia,or urinary tract infection(UTI)[1].Fortunately,reliable guidelines for assessing the risk of SB I in febrile infants have been developed to help determine whether an infant should be hospitalized,undergo lumbar puncture,or be treated with antibiotics[2].However,many hospitals do not have written institutional guidelines,so clinicians often make decisions based on their own experience and knowledge[3-5].For a consistent approach to febrile infants,our hospital plans to introduce written *** this study,we estimated the expected effects of these guidelines and compared our data with the results of previous domestic studies.

关键词： febrile infection urinary

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Scratch formation and its mechanism in chemical mechanical planarization (CMP)

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Friction 2013年第4期1卷 279-305页

作者： tae-young KWON Manivannan RAMACHANDRAN Jin-Goo PARK Department of Materials Engineering Hanyang UniversityAnsan 426-791Korea

Chemical mechanical planarization(CMP)has become one of the most critical processes in semiconductor device fabrication to achieve global *** achieve an efficient global planarization for device node dimensions of less than 32 nm,a comprehensive understanding of the physical,chemical,and tribo-mechanical/chemical action at the interface between the pad and wafer in the presence of a slurry medium is *** the CMP process,some issues such as film delamination,scratching,dishing,erosion,and corrosion can generate defects which can adversely affect the yield and *** this article,an overview of material removal mechanism of CMP process,investigation of the scratch formation behavior based on polishing process conditions and consumables,scratch formation mechanism and the scratch inspection tools were extensively *** advantages of adopting the filtration unit and the jet spraying of water to reduce the scratch formation have been *** current research trends in the scratch formation,based on modeling perspective were also discussed.

关键词： Chemical mechanical planarization(CMP) defects,scratch post-CMP cleaning defect source

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Hepatic artery pseudoaneurysm caused by acute idiopathic pancreatitis

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World Journal of Gastroenterology 2012年第18期18卷 2291-2294页

作者： Yeon Hwa Yu Joo Hyun Sohn tae Yeob Kim Jae yoon Jeong Dong Soo Han Yong Cheol Jeon Min young Kim Department of Internal Medicine Hanyang University College of MedicineGuriGyunggi-Do 471-701South Korea Department of Radiology Hanyang University College of MedicineGuri 471-701South Korea

Hepatic artery pseudoaneurysm(HAP) is a very rare disease but in cases of complication,there is a very high *** most common cause of HAP is iatrogenic trauma such as liver biopsy,transhepatic biliary drainage,cholecystectomy and *** may also occur with complications such as infections or inflammation associated with septic *** has been reported rarely in patients with acute *** far as we are aware,there is no report of a case caused by acute idiopathic pancreatitis,*** report a case of HAP caused by acute idiopathic pancreatitis which developed in a 61-year-old *** woman initially presented with acute pancreatitis due to unknown *** conservative management,her symptoms seemed to have *** eight days after admission,abdominal pain abruptly became worse *** computed tomography(CT) was rechecked and it detected a new HAP that was not seen in a previous abdominal *** retrograde cholangiopancreatography(ERCP) was performed because of a suspicion of hemobilia as a cause of aggravated abdominal *** confirmed hemobilia by observing fresh blood clots at the opening of the ampulla and several filling defects in the distal common bile duct on *** any particular treatment such as embolization or surgical ligation,HAP thrombosed *** months after discharge,abdominal CT demonstrated that HAP in the left lateral segment had disappeared.

关键词： Hepatic artery Pseudoaneurysm Pancreatitis Acute Hemobilia

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Performance evaluations on inner vs. outer decomposition first parallel join algorithms for two nested loop joins

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Journal of Central South University 2014年第10期21卷 3873-3882页

作者： Seo-young NOH Heejun yoon Il-Yeon YEO yoon-su JEONG Hyungwoo PARK National Institute of Supercomputing and Networking Korea Institute of Science and Technology Information Department of Information Communication Engineering Mokwon University

Two popular traditional join algorithms and their parallel versions are introduced. When designing join algorithms in serial computing environment, decomposing inner relation is considered as the right direction to save disk I/Os. However, two different decomposition algorithms are compared, such as inner vs. outer decomposition first algorithms for tuple-based and block-based nested loop joins, showing that the proposed approach is 20% better than general approach. Also lemmas are proved, when we have to use the outer decomposition first parallel join algorithms.

关键词： parallel join performance inner decomposition outer decomposition

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Temporary severe oculomotor nerve palsy after reconstruction of orbital medial wall fracture: a case report of nonfamiliar complication

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International Journal of Ophthalmology(English edition) 2022年第6期15卷 1032-1034页

作者： Yeon Woong Chung tae yoon La Department of Ophthalmology St.Vincent's HospitalCollege of Medicinethe Catholic University of KoreaSuwon 16247Republic of Korea

Dear Editor, Commonly known complications following reconstruction of an orbital fracture include diplopia, hemorrhage, and displacement or infection of the orbital implant, and some studies have reported ptosis cause... 详细信息

关键词： fracture orbital dip

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Chuna Therapy for Musculoskeletal Pain:A Systematic Review of Randomized Clinical Trials in Korean Literature

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Chinese Journal of Integrative Medicine 2013年第3期19卷 228-232页

作者： tae-Woong Moon tae-young Choi tae-Yong Park Myeong Soo Lee Brain Disease Research Center Korea Institute of Oriental Medicine

Objective： To evaluate the effectiveness of Chuna for the treatment of musculoskeletal pain as reported in Korean literature. Methods： We conducted an electronic literature search using seven Korean databases and manually searched six traditional Korean medicine journals. Risk of bias was assessed with the Cochrane criteria. Results： Six randomized controlled trials （RCTs） were included in the study. Compared with standard care, three RCTs suggested favorable effects of Chuna on neck pain due to a hypolordotic cervical spine, low back pain caused by traffic accidents, and low back pain. In contrast, compared with standard care, three RCTs failed to show positive effects on temporomandibular joint disorder, mandibular movement, and neck pain caused by traffic accidents. Conclusions： Currently, the evidence of the effectiveness of Chuna for the treatment of musculoskeletal pain is not convincing. Further rigorously designed trials are warranted to determine its effectiveness.

关键词： Chuna musculoskeletal pain systematic review Korean literature

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Real time shear wave elastography in chronic liver diseases:Accuracy for predicting liver fibrosis,in comparison with serum markers

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World Journal of Gastroenterology 2014年第38期20卷 13920-13929页

作者： Jae yoon Jeong tae Yeob Kim Joo Hyun Sohn Yongsoo Kim Woo Kyoung Jeong young-Ha Oh Kyo-Sang Yoo Department of Gastroenterology Hanyang University College of Medicine Department of Internal Medicine Hanyang Univesity Guri Hospital Department of Radiology Hanyang University College of Medicine Department of Radiology Samsung Medical CenterSungkyunkwan University School of Medicine Department of Pathology Hanyang University College of Medicine

AIM: To evaluate the correlation between liver stiffness measurement (LSM) by real-time shear wave elastography (SWE) and liver fibrosis stage and the accuracy of LSM for predicting significant and advanced fibrosis, ... 详细信息

关键词： Elastography Liver fibrosis Liver stiffness Liver biopsy Serum markers

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