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Mechanism of action, benefits, and research gap in fermented soybean meal utilization as a high-quality protein source for livestock and poultry

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Animal Nutrition 2024年第1期16卷 130-146页

作者： Modinat t.Lambo Haokai Ma Haosheng Zhang Peng Song Hongxiang Mao Guowen cui Baisheng Dai Yang Li Yonggen Zhang college of Animal Science and technology Northeast Agricultural University Wilmar (Shanghai) Biotechnology Research and Development center co. Ltd college of Electrical Engineering and Information Northeast Agricultural University

Animal nutritionists have incessantly worked towards providing livestock with high-quality plant protein feed *** meal (SBM) has been an essential and predominantly adopted vegetable protein source in livestock feeding for a long time;however,several SBM antinutrients could potentially impair the animal's performance and growth,limiting its *** processing methods have been employed to remove SBM antinutrients,including fermentation with fungal or bacterial *** to the literature,fermentation,a traditional food processing method,could improve SBM's nutritional and functional properties,making it more suitable and beneficial to *** current interest in health-promoting functional feed,which can enhance the growth of animals,improve their immune system,and promote physiological benefits more than conventional feed,coupled with the ban on the use of antimicrobial growth promoters,has caused a renewed interest in the use of fermented SBM (FSBM) in livestock *** review details the mechanism of SBM fermentation and its impacts on animal health and discusses the recent trend in the application and emerging advantages to livestock while shedding light on the research gap that needs to be critically addressed in future *** appears to be a multifunctional high-quality plant protein source for *** removing soybean antinutrients,beneficial bioactive peptides and digestive enzymes are produced during fermentation,providing probiotics,antioxidants,and immunomodulatory *** aspects regarding FSBM feeding to animals remain uncharted,such as the duration of fermentation,the influence of feeding on digestive tissue development,choice of microbial strain,and possible environmental impact.

关键词： Soybean meal Protein feed Fermentation Microorganism Livestock

carbon coated LaFe_(0.92)Pd_(0.08)O_(3) composites for catalytic transfer hydrogenation:Balance in the ability of substrates adsorption and conversion

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Nano Research 2024年第5期17卷 3724-3732页

作者： Bowen Wang Nan Zhang Ping Xiao Jian Zhang Sónia A.c.carabineiro Junjiang Zhu Hubei Key Laboratory of Biomass Fibers and Eco-dyeing&Finishing College of Chemistry and Chemical EngineeringWuhan Textile UniversityWuhan 430200China college of chemistry and Materials Engineering Wenzhou UniversityWenzhou 325035China LAQV-REQUIMtE Department of ChemistryNOVA School of Science and TechnologyUniversidade NOVA de LisboaLargo da Torre2829-516 CaparicaPortugal

catalytic transfer hydrogenation(ctH)is a green and efficient pathway for selective hydrogenation of unsaturated aldehydes and ***,managing the abilities of solid catalysts to adsorb substrates and to convert them into desired products is a challenging ***,we report the synthesis of carbon coated LaFe_(0.92)Pd_(0.08)O_(3) composites(LFPO-8@c)for ctH of benzaldehyde(BzH)into benzyl alcohol(BzOH),using isopropanol(IPA)as hydrogen *** coating with carbon improves the ability to adsorb/transfer reactants from solution to active sites,and the doping of Pd2+at Fe3+site strengthens the ability of LaFeO_(3) to convert BzH into BzOH.A balanced point between them(i.e.,abilities to adsorb BzH and to convert BzH into BzOH)is obtained at LFPO-8@c,which exhibits a BzOH formation rate of 3.88 mmol·gcat^(-1)·h^(-1) at 180℃ for 3 h,which is 1.50 and 2.72 times faster than those of LFPO-8 and LaFeO_(3)@c.A reaction mechanism is proposed,in which the acidic sites(e.g.,Fe^(4+),oxygen vacancy)are used for the activation of c=O bond of BzH and O-H bond of IPA,and the basic sites(e.g.,lattice oxygen)for the activation ofα-H(O-H)bond of IPA.

关键词： LaFe_(0.92)Pd_(0.08)O_(3) porous carbon catalytic transfer hydrogenation isopropanol reaction mechanism

Satellite-enabled enviromics to enhance crop improvement

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Molecular Plant 2024年第6期17卷 848-866页

作者： Rafael t.Resende Lee Hickey cibele H.Amaral Lucas L.Peixoto Gustavo E.Marcatti Yunbi Xu Universidade Federal de Goia´s(UFG) Agronomy DepartmentPlant Breeding SectorGoiania(GO)74690-900Brazil thecROP a Precision-Breeding Startup:EnviromicsPhenomicsand GenomicsNo Zip-codeOperating VirtuallyGoiania(GO)and Sete Lagoas(MG)Brazil Queensland Alliance for Agriculture and Food Innovation The University of QueenslandBrisbaneQLDAustralia Earth Lab Cooperative Institute for Research in Environmental SciencesUniversity of Colorado BoulderBoulderCO 80303USA Environmental Data Science Innovation&Inclusion Lab Cooperative Institute for Research in Environmental SciencesUniversity of Colorado BoulderBoulderCO 80303USA Universidade Federal de Sa˜o Joa˜o del-Rei Forest Engineering DepartmentCampus Sete LagoasSete Lagoas(MG)35701-970Brazil Institute of crop Sciences Chinese Academy of Agricultural SciencesBeijing 100081China Peking University Institute of Advanced Agricultural Sciences WeifangShandong 261325China BGI Bioverse Shenzhen 518083China

Enviromics refers to the characterization of micro-and macroenvironments based on large-scale environmental *** providing genotypic recommendations with predictive extrapolation at a site-specific level,enviromics could inform plant breeding decisions across varying conditions and anticipate productivity in a changing ***-based integration of statistics,envirotyping(i.e.,determining environmental factors),and remote sensing could help unravel the complex interplay of genetics,environment,and *** support this goal,exhaustive envirotyping to generate precise environmental profiles would significantly improve predictions of genotype performance and genetic gain in ***,informatics management platforms aggregate diverse environmental datasets obtained using optical,thermal,radar,and light detection and ranging(LiDAR)sensors that capture detailed information about vegetation,surface structure,and *** wealth of information,coupled with freely available climate data,fuels innovative enviromics *** enviromics holds immense potential for breeding,a few obstacles remain,such as the need for(1)integrative methodologies to systematically collect field data to scale and expand observations across the landscape with satellite data;(2)state-of-the-art AI models for data integration,simulation,and prediction;(3)cyberinfrastructure for processing big data across scales and providing seamless interfaces to deliver forecasts to stakeholders;and(4)collaboration and data sharing among farmers,breeders,physiologists,geoinformatics experts,and programmers across research *** these challenges is essential for leveraging the full potential of big data captured by satellites to transform 21st century agriculture and crop improvement through enviromics.

关键词： envirotyping precision breeding genotype-environment interactions remote sensing predictive models enviromic information

Direct anterior approach hip arthroplasty:How to reduce complications-A 10-years single center experience and literature review

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World Journal of Orthopedics 2022年第4期13卷 388-399页

作者： fabrizio Rivera Luca c comba Alessandro Bardelli Department of Orthopedic trauma SS Annunziata HospitalSavigliano 12038Italy Department of Orthopedic trauma Universitàdegli Studi di TorinoTorino 10124Italy

BAcKGROUND the direct anterior approach for total hip arthroplasty(DAA-tHA)is increasing in popularity due to some advantages such as less surgical trauma,minimal dissection of soft tissues,shorter rehabilitation times,faster return to daily activities,lower incidence of *** the other hand,the literature reports a high rate of intraoperative complications,with many different rates and complication types in the published *** to analyze our complications comparing results with the literature;to report measures that we have taken to reduce complications *** All DAA-tHA patients with one year minimum follow up who were operated at a single high-volume centre,between January 2010 and December 2019 were included in this retrospective *** surgeries were performed using cementless short anatomical or straight stems and press fit ***’followup was performed,at 6 wk,3 mo,then annually post-surgery with clinical and radiological *** outcomes were stem revision for aseptic loosening and all-cause stem *** outcome was intra-operative and post-operative complications *** A total of 394 patients underwent DDA-tHA from January 2010 and December 2019,for a total of 412 hips;twelve patients lost to follow-up and one patient who died from causes not related to surgery were excluded from the *** average age at the time of surgery was 61 years(range from 28 to 78 years).Mean follow-up time was 64.8 mo(range 12-120 mo).Seven stems were *** cortical perforation,one trochanteric and lateral cortical wall intraoperative fracture,one diaphyseal fracture,three clinically symptomatic early subsidence and one late aseptic *** also observed 3 periprosthetic fractures B1 according to the Vancouver *** minor complications not requiring stem revision were 5 un-displaced fractures of the calcar region treated with preventive cerclage,one early infection,one case of late pos

关键词： Hip arthroplasty Direct anterior approach Short hip stem Minimally invasive surgery complications

Porphyrins,phthalocyanines,and related covalent-organic frameworks in the photochemical and electrochemical water splitting:A review

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Particuology 2024年第7期90卷 236-265页

作者： Oxana V.Kharissova Yolanda Peña Méndez Boris I.Kharisov Aleksandr LNikolaev Edith Luévano-Hipólito Lucy t.González Universidad Autónoma de Nuevo León Ave.Universidad s/nSan Nicolás de los GarzaNuevo León66455Mexico Department of chemistry Moscow State UniversityVorobievy HillsMoscowRussia cONAcYt-Universidad Autónoma de Nuevo León Facultad de Ingeniería Civil-Departamento de Ecomateriales y EnergíaCd.UniversitariaC.P.66455San Nicolás de los GarzaNLMexico tecnologico de Monterrey Escuela de Ingeniería y CienciasMonterreyNuevo León 64890Mexico tecnologico de Monterrey Centro del AguaMonterreyNuevo León 64890Mexico

In this review,the possibilities of photochemical and electrochemical water splitting(WS)using porphyrins,phthalocyanines,related macrocycles,and their metal complexes are *** efforts are being carried out in order to develop novel and cheap methods for water decomposition to generate inexhaustible greener energy sources(molecular hydrogen)instead of oil and *** processes of WS in heterogeneous and homogeneous media require novel photo-and electrocatalysts,in particular those on macrocycle basis.A high WS efficiency has been observed for porphyrins and phthalocyanines,showing their suitability both for HER and OER processes are available using these relative compounds for WS *** can be used in photocatalytic and electrocatalytic WS processes both in their free forms or as metal porphyrins/porphyrinates,mainly loaded on various inorganic materials,such as Au NPs,c_(3)N_(4),GaP,KtaO_(3),GaP,and so on,as part of porphyrin-containing polymers or on electrode surface as modifying coatings,being sometimes better than commercial catalysts,such as Pt/*** H2 evolution can be considerably depended on the shape of porphyrin particles;in particular,porphyrin nanowires can yield up to 20 times more H2 than its *** certain cases,both HER and OER can be driven in the same electrolyte using metal *** capacity of metal porphyrins to generate ROS(in particular,singlet oxygen 1O_(2))under ultrasonic treatment is known and can be successfully used for H_(2)O_(2) and O_(2) *** can be used in similar processes in free form or as composites with inorganic or organic counterparts,being immobilized on nanocarbons,metal oxides and salts,or simply dissolved in water acting in a homogeneous *** additional use of ultrasound can lead to better results due to the synergistic effect of the sonochemical treatment and ***-organic frameworks are also applied for WS purposes and are mainly based

关键词： Porphyrins Phthalocyanines cOFs Water splitting Photocatalysis Electrocatalysis

Lack of transcriptional coordination between mitochondrial and nuclear oxidative phosphorylation genes in the presence of two divergent mitochondrial genomes

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Zoological Research 2022年第1期43卷 111-128页

作者： Ran Xu Mariangela Iannello Justin cHavird Liliana Milani fabrizio Ghiselli Department of Biological Geological and Environmental SciencesUniversity of BolognaBolognaBO 40126Italy Department of Integrative Biology The University of Texas at AustinAustinTX 78712USA

In most eukaryotes,oxidative phosphorylation(OXPHOS)is the main energy production process and it involves both mitochondrial and nuclear *** close interaction between the two genomes is critical for the coordinated function of the OXPHOS *** bivalves show doubly uniparental inheritance(DUI)of mitochondria,where two highly divergent mitochondrial genomes,one inherited through eggs(F-type)and the other through sperm(M-type),coexist in the same ***,it remains a puzzle how nuclear OXPHOS genes coordinate with two divergent mitochondrial genomes in DUI *** this study,we compared transcription,polymorphism,and synonymous codon usage in the mitochondrial and nuclear OXPHOS genes of the DUI species Ruditapes philippinarum using sex-and tissue-specific *** and nuclear OXPHOS genes showed different transcription *** co-transcription signal was observed within mitochondrial(separate for F-and M-type)and within nuclear OXPHOS genes but the signal was weak or absent between mitochondrial and nuclear OXPHOS genes,suggesting that the coordination between mitochondrial and nuclear OXPHOS subunits is not achieved ***-Kreitman and frequency-spectrum based tests indicated that M-type OXPHOS genes deviated significantly from neutrality,and that F-type and M-type OXPHOS genes undergo different selection *** usage analysis revealed that mutation bias and translational selection were the major factors affecting the codon usage bias in different OXPHOS genes,nevertheless,translational selection in mitochondrial OXPHOS genes appears to be less efficient than nuclear OXPHOS ***,we speculate that the coordination between OXPHOS genes may involve post-transcriptional/translational regulation.

关键词： Oxidative phosphorylation Doubly uniparental inheritance co-transcription Polymorphism codon usage bias translational selection

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Low-loss and polarization insensitive 32×4 optical switch for ROADM applications

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Light(Science & Applications) 2024年第5期13卷 875-884页

作者： Xiaotian Zhu Xiang Wang Yanlu Huang Liyan Wu chunfei Zhao Mingzhu Xiao Luyi Wang Roy Davidson Yanni Ou Brent E.Little Sai t.chu Department of Physics City University of Hong KongTat Chee AvenueHong KongChina. QXP technologies Inc. NO.15th Shanglinyuan 1st RoadXi’anShaanxi 710119China. State Key Laboratory of Information of Photonics and Optical communications School of Electronic EngineeringBeijing University of Posts and TelecommunicationsBeijing 100876China

Integrated switches play a crucial role in the development of reconfigurable optical add-drop multiplexers(ROADMs)that have greater flexibility and compactness,ultimately leading to robust single-chip *** decades of research on switches with various structures and platforms,achieving a balance between dense integration,low insertion loss(IL),and polarization-dependent loss(PDL)remains a significant *** this paper,we propose and demonstrate a 32×4 optical switch using high-index doped silica glass(HDSG)for ROADM *** switch is designed to route any of the 32 inputs to the express ports or drop any channels from 32 inputs to the target 4 drop ports or add any of the 4 ports to any of the 32 express *** switch comprises 188 MachZehnder Interferometer(MZI)type switch elements,88 optical vias for the 44 optical bridges,and 618 waveguidewaveguide crossings with three-dimensional(3D)*** 1550 nm,the fiber-to-fiber loss for each express channel is below 2 dB,and across the c and L bands,below 3 *** each input channel to all 4 drop/add channels at 1550 nm,the loss is less than 3.5 dB and less than 5 dB across the c and L *** PDLs for all express and input channels to the 4 drop/add channels are below 0.3 dB over the c band,and the crosstalk is under−50 dB for both the c and L bands.

关键词： polarization ROADM optical

cD4^(+)t cells produce IFN-I to license cDc1s for induction of cytotoxic t-cell activity in human tumors

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cellular & Molecular Immunology 2024年第4期21卷 374-392页

作者： Xin Lei Daniël c.de Groot Marij J.P.Welters tom de Wit Ellen Schrama Hans van Eenennaam Saskia J.Santegoets timo Oosenbrug Annemarthe van der Veen Joris L.Vos charlotte L.Zuur Noel F.c.c.de Miranda Heinz Jacobs Sjoerd H.van der Burg Jannie Borst Yanling Xiao Department of Immunology Leiden University Medical CenterLeidenThe Netherlands Oncode Institute Leiden University Medical CenterLeidenThe Netherlands Department of tumor Biology and Immunology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Medical Oncology Oncode InstituteLeiden University Medical CenterLeidenThe Netherlands IMMIOS B.V. OssThe Netherlands Division of Medical Oncology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Otorhinolaryngology Leiden University Medical center LeidenThe Netherlands Department of Pathology Leiden University Medical CenterLeidenThe Netherlands

cD4^(+)t cells can"help"or"license" conventional type 1 dendritic cells(cDc1s)to induce cD8^(+)cytotoxic t lymphocyte(ctL)anticancer responses,as proven in mouse *** recently identified cDc1s with a transcriptomic imprint of cD4^(+)t-cell help,specifically in t-cell-infiltrated human cancers,and these cells were associated with a good prognosis and response to PD-1-targeting ***,we delineate the mechanism of cDc1 licensing by cD4^(+)t cells in *** cD4^(+)t cells produce IFNβvia the StING pathway,which promotes MHc-I antigen(cross-)presentation by cDc1s and thereby improves their ability to induce ctL anticancer *** cooperation with cD40 ligand(L),IFNβalso optimizes the costimulatory and other functions of cDc1s required for ctL response ***-I-producing cD4^(+)t cells are present in diverse t-cell-infiltrated cancers and likely deliver“help”signals to ctLs locally,according to their transcriptomic profile and colocalization with“helped/licensed”cDcs and tumor-reactive cD8^(+)t *** agreement with this scenario,the presence of IFN-I-producing cD4^(+)t cells in the tME is associated with overall survival and the response to PD-1 checkpoint blockade in cancer patients.

关键词： cD4^(+)t-cell help cDc1 licensing IFN-I signaling cD40 costimulation (cross-)presentation ctL priming tumor control

肾脏恶性肿瘤冷冻消融术后早期对比增强：影像表现与良性相关

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国际医学放射学杂志 2024年第1期 130-131页

作者： t.Grand c.Delavaud c.Dariane t.Ramtohul S.Guinebert O.Hélénon 李江

摘要目的肾脏恶性肿瘤冷冻消融术后早期MRI对比增强可能提示肿瘤残留（Rt）。但冷冻消融术后48 h内MRI上出现强化的病人在6周后没有对比度增强，研究旨在分析

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