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EFFECtS OF HDDR PROCESS ON StRUCtURE AND MAGNEtIC PROPERtIES OF Nd(Fe,ti)_(12)N_δ PREPARED BY MECHANICAL ALLOYING

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Acta Metallurgica Sinica(English Letters) 1998年第1期11卷 68-78页

作者： B.ZCui X.K.Sun X.G.zhao W.Liu Q.F.Xiao t.zhao Z.D.Zhang Y.C.Sui Chinese Acad of Sciences Shenyang China

the effects of the hydrogenation-disproportionation-desorption-recombination (HDDR) process on the structure and the magnetic properties of the mechanical alloying (MA) prepared Nd8Fe84 ti8 alloy and its nitride counterpart have been studied in detail. It has been found that Nd(Fe, ti)12Hδ is formed in the temperature range from 300 to 550°℃. the disproportionation is ready to start at 550°℃ and is complete at 960°℃.the desorption and the recombination are almost synchronized. the phase of Nd(Fe,ti)7 is formed at 750°℃ during the HDDR treatment. With increasing temperature of HDDR process, the metastable structure of tbCu7 type is gradually transformed into the structure of thMn12 type. the intrinsic coercivity and the maximum magnetic energy product increase with increasing temperature of HDDR process.

关键词： Nd(Fe ti)_(12)N_δ compound,magnetic property hydrogenation

Anthocyanin-assisted Agrobacterium infiltration for the rapid evaluation of genome editing efficiencies across multiple plant species

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National Science Open 2023年第5期2卷 11-24页

作者： Sinian Xing Yu Sun Boshu Li Hongchao Li Kevin t.zhao Kunling Chen Caixia Gao State Key Laboratory of Plant Cell and Chromosome Engineering Center for Genome EditingInstitute of Genetics and Developmental BiologyInnovation Academy for Seed DesignChinese Academy of SciencesBeijing 100101China College of Life Sciences University of Chinese Academy of SciencesBeijing 100101China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China

CRISPR-based genome editing technologies continue to drive major advances in life sciences.A major challenge for realizing widespread use of genome editing in plants and agriculture is establishing methods that enable the rapid,comprehensive,and precise evaluation of editing technologies using transient *** we report a new and rapid genome editing evaluation method using Agrobacterium infiltration techniques to enable broad-spectrum,simplistic,and precise assessments of genome editing *** employed an anthocyanin marker to facilitate visual screenings of genome-edited cells for use in adult strawberry fruits as well as tomato fruits,cotton leaves,and sugar beet *** this method,we demonstrate the ability to quickly measure genome editing efficiencies mediated by SpCas9,LbCas12a,A3A-PBE,ABE8e,and *** new method will allow researchers to rapidly and easily evaluate genome editing tools across a broad spectrum of plant species,further expediting the development of genome-edited agricultural crops.

关键词： genome editing Agrobacterium infiltration anthocyanin transient transformation geminivirus replicon strawberry tomato

PslG,a Self-produced Glycosyl Hydrolase triggers Biofilm Disassembly by Disrupting Exopolysaccharide Matrix

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PslG,a Self-produced Glycosyl Hydrolase Triggers Biofilm Dis...

“Zero‑Strain” NiNb_(2)O_(6) Fibers for All‑Climate Lithium Storage

中国生物工程学会第六次全国会员代表大会暨第九届学术年会

作者： S.Yu t.Su H.Wu S.Liu D.Wang t.zhao Z.Jin W.Du M.Zhu S.Chua L.Yang D.Zhu L.Gu 马旅雁 Institute of Microbiology Chinese Academy of Sciences University of the Chinese Academy of Sciences Shandong University Washington State University Nanyang technological University 中国科学院微生物研究所

Biofilms are surface-associated communities of microorganism embedded in extracellular matrix. Exopolysaccharide is a critical component in the extracellular matrix that maintains biofilm architecture and protects resident biofilm bacteria from antimicrobials and host immune attack. However, the self-produced factors that target the matrix exopolysaccharides, are poorly understood. Here we show that PslG,

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Nano-Micro Letters 2025年第1期17卷 348-360页

作者： Yan zhao Qiang Yuan Liting Yang Guisheng Liang Yifeng Cheng Limin Wu Chunfu Lin Renchao Che College of Physics Donghua UniversityShanghai 201620People’s Republic of China School of Materials Science and Engineering Institute of Materials for Energy and EnvironmentQingdao UniversityQingdao 266071People’s Republic of China Laboratory of Advanced Materials Shanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsAcademy for Engineering&TechnologyFudan UniversityShanghai 200438People’s Republic of China Zhejiang Laboratory Hangzhou 311100People’s Republic of China Inner Mongolia University Hohhot 010021People’s Republic of China

Niobates are promising all-climate Li^(+)-storage anode material due to their fast charge transport,large specific capacities,and resistance to electrolyte ***,their moderate unit-cellvolume expansion(generally 5%–10%)during Li^(+)storage causes unsatisfactory long-term ***,“zero-strain”NiNb_(2)O_(6) fibers are explored as a new anode material with comprehensively good electrochemical *** Li^(+)storage,the expansion of electrochemical inactive NiO_(6) octahedra almost fully offsets the shrinkage of active NbO_(6) octahedra through reversible O *** superior volume-accommodation capability of the NiO_(6) layers guarantees the“zero-strain”behavior of NiNb_(2)O_(6) in a broad temperature range(0.53%//0.51%//0.74%at 25//−10//60℃),leading to the excellent cyclability of the NiNb_(2)O_(6) fibers(92.8%//99.2%//91.1%capacity retention after 1000//2000//1000 cycles at 10C and 25//−10//60℃).this NiNb_(2)O_(6) material further exhibits a large reversible capacity(300//184//318 mAh g−1 at 0.1C and 25//−10//60℃)and outstanding rate performance(10 to 0.5C capacity percentage of 64.3%//50.0%//65.4%at 25//−10//60℃).therefore,the NiNb_(2)O_(6) fibers are especially suitable for large-capacity,fast-charging,long-life,and all-climate lithium-ion batteries.

关键词： NiNb_(2)O_(6)porous fiber “Zero-strain”mechanism Electrochemical property Harsh-temperature operation Operando characterization

用激光分子束外延的YBCO薄膜制备高稳定性DC-SQUID

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低温物理学报 1999年第1期21卷 14-17页

作者：王晶陈凡赵彤韩冰徐凤枝吕惠宾陈赓华周岳亮陈正豪杨乾声杨国桢中科院物理所凝聚态物理中心

利用激光分子束外延法在高约２５０ｎｍ的ＳＴＯ台阶衬底和３６．８°双晶衬底上外延厚度为２００～２３０ｎｍ的ＹＢＣＯ超导薄膜，用常规的光刻工艺制出ＤＣＳＱＵＩＤ图形．器件进入超导态后，正常态电阻不随温度改变．在恒定偏流... 详细信息

利用激光分子束外延法在高约２５０ｎｍ的ＳＴＯ台阶衬底和３６．８°双晶衬底上外延厚度为２００～２３０ｎｍ的ＹＢＣＯ超导薄膜，用常规的光刻工艺制出ＤＣＳＱＵＩＤ图形．器件进入超导态后，正常态电阻不随温度改变．在恒定偏流，７７Ｋ温度下，磁通白噪声为２．０×１０－４Φ０／Ｈｚ．经过４０次室温与液氮温度间循环后，观察不到任何性能的改变

关键词：激光分子束外延法分子束外延双晶结 DC-SQUID YBCO 临界电流薄膜制备

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan zhao Yidan Zhang Xin Liu Jian Zhang Ya Gao Shuyue Li Cui Chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

Low‑temperature Fabrication of Stable Black‑Phase CsPbI_(3)Perovskite Flexible Photodetectors toward Wearable Health Monitoring

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Nano-Micro Letters 2025年第3期17卷 232-245页

作者： Yingjie zhao Yicheng Sun Chaoxin Pei Xing Yin Xinyi Li Yi Hao Mengru Zhang Meng Yuan Jinglin Zhou Yu Chen Yanlin Song College of Chemistry and Pingyuan Laboratory Zhengzhou UniversityZhengzhou 450001People’s Republic of China Key Laboratory of Green Printing Institute of ChemistryChinese Academy of SciencesBeijing 100190People’s Republic of China Key Laboratory of Bio‑Inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190People’s Republic of China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049People’s Republic of China

Flexible wearable optoelectronic devices fabricated fromorganic–inorganic hybrid perovskites significantly accelerate the developmentof portable energy,biomedicine,and sensing fields,but their poor thermal stabilityhinders further ***,all-inorganic perovskites possessexcellent thermal stability,but black-phase all-inorganic perovskite filmusually requires high-temperature annealing steps,which increases energy consumptionand is not conducive to the fabrication of flexible wearable *** this work,an unprecedented low-temperature fabrication of stable blackphaseCsPbI3perovskite films is demonstrated by the in situ hydrolysis reactionof diphenylphosphinic chloride *** released diphenyl phosphateand chloride ions during the hydrolysis reaction significantly lower the phasetransition temperature and effectively passivate the defects in the perovskitefilms,yielding high-performance photodetectors with a responsivity of 42.1 AW−1 and a detectivity of 1.3×10^(14)***,high-fidelity imageand photoplethysmography sensors are demonstrated based on the fabricated flexible wearable *** work provides a newperspective for the low-temperature fabrication of large-area all-inorganic perovskite flexible optoelectronic devices.

关键词： In situ hydrolyzation Low-temperature processing All-inorganic perovskite Flexible photodetectors Health monitoring

Dietary carbohydrate intake and risk of type 2 diabetes:a 16-year prospective cohort study

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Science China Life Sciences 2025年

作者： Lu Gan Yi Yang Bin zhao Kai Yu Kehua Guo Fang Fang Zhiguang Zhou Demetrius Albanes Jiaqi Huang Key Laboratory of Diabetes Immunology Ministry of Education and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University CSU-Sinocare Research Center for Nutrition and Metabolic Health Xiangya School of Public Health Central South UniversityFurong Laboratory Division of Cancer Epidemiology and Genetics National Cancer Institute NIH Department of Health and Human Services School of Computer Science and Engineering Central South University Institute of Environmental Medicine Karolinska Institute National Clinical Research Center for Metabolic Diseases Key Laboratory of Diabetes Immunology Ministry of Education and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University

Despite considerable research underscoring the importance of carbohydrate intake in relation to the risk of type 2 diabetes(t2D), a comprehensive assessment of this relationship is currently lacking. We aimed to examine the associations of various types and food sources of dietary carbohydrate intake with the risk of t2D, to evaluate potential effect modification by other factors, including genetic susceptibility,and to explore the potential mediators for such associations. the present study included 161,872 participants of the UK Biobank who were free of prevalent cancer, cardiovascular disease, or diabetes, and had at least one validated 24-h dietary recall assessment. Multivariableadjusted age-stratified Cox proportional hazard regression models were applied to estimate hazard ratios(HRs) and 95% confidence intervals(CI) for the associations of various types and food sources of dietary carbohydrate intake with risk of t2D. During a median follow-up of13.6 years, 4,176 incident cases of t2D were identified. In the multivariable-adjusted models, a greater intake of fiber, carbohydrates from whole grains, and carbohydrates from non-starchy vegetables was significantly associated with a lower risk of t2D(highest vs. lowest quantile, HR [95% CI]=0.70 [0.62–0.79], 0.74 [0.67–0.82], and 0.83 [0.75–0.92], respectively, all P for trend trast, a higher intake of starch and carbohydrate from starchy vegetables was associated with an increased risk of t2D(highest vs. lowest quantile, HR [95%CI]=1.31 [1.16–1.48] and 1.19 [1.09–1.31], respectively, both P for trend tarchy vegetables with an equal amount of whole grains or non-starchy vegetables was associated with 4% to 10% lower risk of t2D(all P values the observed associations were generally similar across population subgroups, including individuals with different genetic susceptibility to t2D. Mediation analyses of the inverse association between t

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Polynaphthoxazines-Montmorillonite Nanocomposites: Synthesis and Characterization

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Chinese Chemical Letters 2001年第10期12卷 935-936页

作者： Wang, CY zhao, t Chinese Acad Sci Inst Chem Ctr Mol Sci Beijing 100080 Peoples R China

Polynaphthoxazines-clay nanocomposites were prepared from 1, 5-dihydroxynaphthalene, aniline, formaldehyde and different proportion montmorillonite(MMt) by in-situ reaction in ethanol. Dynamic tGA showed that nanocomposites have delayed decomposition temperatures when compared with pristine polynaphthoxazine indicating the enhancement in the thermal stability.

关键词： nanocomposites polynaphthoxazine montmorillonite