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Optimal Design Methods Based on Creative Simplification and Clarification of Conflicting and Cooperative Relationships

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Optimal Design Methods Based on Creative Simplification and ...

Damped Oscillation of Liquid Column in Vertical U-tube for Newtonian and non-Newtonian Liquids

the Fourth World Congress of Structural and Multidisciplinary Optimization

作者： Yoshimura M satou t Department of Precision Engineering Graduate School of Engineering Kyoto University Kyoto JAPAN

this paper proposes a method for obtaining superior design solutions by first simplifying the overall design problem and design elements, and then reconstructing a fresh design system based on the simplified model. this process of simplification followed by reconstruction not only makes design optimization easier, but also increases the possibilities for discovering improved designs. After simplifying the problem, conflicting and cooperative relationships are clarified, and then the core relationships among the design characteristics are identified. Optimization methods are carried out on the reconstructed formulation, paying particular attention to the newly identified core relationships. An optimal design solution is selected from a set of obtained design alternatives that consider both the individual parts of the product as well as the design as a whole.

关键词： Optimum Design Global optimum Global Sensitivities Simplification Conflicting Relationships

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Journal of thermal Science 2007年第4期16卷 289-300页

作者： Akira Ogawa Suguru tokiwa Masatoshi Mutou Kazutaka Mogi tonau Sugawara Masahide Watanabe Kouhei satou toshikazu Kikawada Keitarou Shishido Naoya Matumoto t110-0011.Minowa 2-14-7 Taitou-KuTokyoJapan Asnohorie Co.Ltd. Japan Yamada manufacturing Co.Ltd. Japar Polymatech Co.Ltd. japan Fujikura Rubber Com. Japan Furukawa Electric Co.Ltd. Japan GMA Co.Ltd. Japan top Corporation Co.Ltd. Japan Hitachi Unisia Co.Ltd. Japan Research Student Japan

Damped oscillation of Newtonian liquid in a vertical U-tube is one of the well known phenomena and the solution of this liquid motion for the laminar flow regime in the circular pipe was solved, however, generally speaking, even if the period of the oscillational motion by this solution is nearly coincided with that of the experimental result, the estimation of the damped oscillational process with lapse of time by the solved equation is not in agreement with that of the experimental result. therefore basing upon the experimental results of the velocity distributions of the oscillational motion in the circular U-tube for the Newtonian and non-Newtonian liquids, the velocity distribution of the Bingham plastic flow is assumed. the solutions of the damped oscillation and also of the vertical falling and rising velocities of the free surface in the vertical U-tube of the diameters D= 10mm, 20mm and 40mm are compared with water and water-glycerine solution for the Newtonian liquids and the acrylic co-polymer solutions for the non-Newtorlian liquid. the comparisons of these solved equations by the new flow model are shown in good agreement with the experimental results. the above stated results are described in detail.

关键词： Damped oscillation Bingham plastic flow Hagen-Poiseuille law Newtonian liquid non-Newtonian liquid.

A novel over-sampling method and its application to miRNA prediction

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Journal of Biomedical Science and Engineering 2013年第2期6卷 236-248页

作者： Xuan tho Dang Osamu Hirose thammakorn Saethang Vu Anh tran Lan Anh t. Nguyen tu Kien t. Le Mamoru Kubo Yoichi Yamada Kenji satou Graduate School of Natural Science and technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

MicroRNAs (miRNAs) are short (~22nt) non-coding RNAs that play an indispensable role in gene regulation of many biological processes. Most of current computational, comparative, and non-comparative methods commonly classify human precursor micro- RNA (pre-miRNA) hairpins from both genome pseudo hairpins and other non-coding RNAs (ncRNAs). Although there were a few approaches achieving promising results in applying class imbalance learning methods, this issue has still not solved completely and successfully yet by the existing methods because of imbalanced class distribution in the datasets. For example, SMOtE is a famous and general over-sampling method addressing this problem, however in some cases it cannot improve or sometimes reduces classification performance. therefore, we developed a novel over-sampling method named incre-mental- SMOtE to distinguish human pre-miRNA hairpins from both genome pseudo hairpins and other ncRNAs. Experimental results on pre-miRNA datasets from Batuwita et al. showed that our method achieved better Sensitivity and G-mean than the control (no over- sampling), SMOtE, and several successsors of modified SMOtE including safe-level-SMOtE and border-line-SMOtE. In addition, we also applied the novel method to five imbalanced benchmark datasets from UCI Machine Learning Repository and achieved improvements in Sensitivity and G-mean. these results suggest that our method outperforms SMOtE and several successors of it in various biomedical classification problems including miRNA classification.

关键词： Imbalanced Dataset Over-Sampling SMOtE miRNA Classification

Predicting residue contacts for protein-protein interactions by integration of multiple information

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Journal of Biomedical Science and Engineering 2014年第1期7卷 28-37页

作者： tu Kien t. Le Osamu Hirose Vu Anh tran thammakorn Saethang Lan Anh t. Nguyen Xuan tho Dang Duc Luu Ngo Mamoru Kubo Yoichi Yamada Kenji satou Graduate School of Natural Science and technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

Detailed knowledge of interfacial region between interacting proteins is not only helpful in annotating function for proteins, but also very important for structure-based drug design and disease treatment. However, this is one of the most difficult tasks and current methods are constrained by some factors. In this study, we developed a new method to predict residue-residue contacts of two interacting protein domains by integrating information about evolutionary couplings andamino acid pairwise contact potentials, as well as domain-domain interaction interfaces. the experimental results showed that our proposed method outperformed the previous method with the same datasets. Moreover, the method promises an improvement in the source of template-based protein docking.

关键词： Residue-Residue Contacts Domain-Domain Interactions Protein-Protein Interactions Domain Interfaces Residue Co-Evolution Contact Potentials

D-IMPACt: A Data Preprocessing Algorithm to Improve the Performance of Clustering

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Journal of Software Engineering and Applications 2014年第8期7卷 639-654页

作者： Vu Anh tran Osamu Hirose thammakorn Saethang Lan Anh t. Nguyen Xuan tho Dang tu Kien t. Le Duc Luu Ngo Gavrilov Sergey Mamoru Kubo Yoichi Yamada Kenji satou Graduate School of Natural Science and technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

In this study, we propose a data preprocessing algorithm called D-IMPACt inspired by the IMPACt clustering algorithm. D-IMPACt iteratively moves data points based on attraction and density to detect and remove noise and outliers, and separate clusters. Our experimental results on two-dimensional datasets and practical datasets show that this algorithm can produce new datasets such that the performance of the clustering algorithm is improved.

关键词： Attraction Clustering Data Preprocessing Density Shrinking

Feature Analysis and Classification of Particle Data from two-Dimensional Video Disdrometer

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Advances in Remote Sensing 2015年第1期4卷 1-14页

作者： Sergey Gavrilov Mamoru Kubo Vu Anh tran Duc Luu Ngo Ngoc Giang Nguyen Lan Anh t. Nguyen Favorisen Rosyking Lumbanraja Dau Phan Kenji satou Graduate School of Natural Science and technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan Department of Computer Science Hue University of Education Hue Vietnam

We developed a ground observation system for solid precipitation using two-dimensional video disdrometer (2DVD). Among 16,010 particles observed by the system, around 10% of them were randomly sampled and manually classified into five classes which are snowflake, snowflake-like, intermediate, graupel-like, and graupel. At first, each particle was represented as a vector of 72 features containing fractal dimension and box-count to represent the complexity of particle shape. Feature analysis on the dataset clarified the importance of fractal dimension and box-count features for characterizing particles varying from snowflakes to graupels. On the other hand, performance evaluation of two-class classification by Support Vector Machine (SVM) was conducted. the experimental results revealed that, by selecting only 10 features out of 72, the average accuracy of classifying particles into snowflakes and graupels could reach around 95.4%, which had not been achieved by previous studies.

关键词： Solid Precipitation Particle Classification 2DVD Fractal Dimension PCA

Predicting Βeta-turns and Βeta-turn types Using a Novel Over-Sampling Approach

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Journal of Biomedical Science and Engineering 2014年第11期7卷 927-940页

作者： Lan Anh t. Nguyen Xuan tho Dang tu Kien t. Le thammakorn Saethang Vu Anh tran Duc Luu Ngo Sergey Gavrilov Ngoc Giang Nguyen Mamoru Kubo Yoichi Yamada Kenji satou Graduate School of Natural Science and technology Kanazawa University Kanazawa Japan Department of Computer Science Hue University of Education Hue Vietnam Institute of Science and Engineering Kanazawa University Kanazawa Japan

β-turn is one of the most important reverse turns because of its role in protein folding. Many computational methods have been studied for predicting β-turns and β-turn types. However, due to the imbalanced dataset, the performance is still inadequate. In this study, we proposed a novel over-sampling technique FOSt to deal with the class-imbalance problem. Experimental results on three standard benchmark datasets showed that our method is comparable with state-of-the-art methods. In addition, we applied our algorithm to five benchmark datasets from UCI Machine Learning Repository and achieved significant improvement in G-mean and Sensitivity. It means that our method is also effective for various imbalanced data other than β-turns and β-turn types.

关键词： Beta-turns Beta-turn types Class-Imbalance Over-Sampling

Elastic Scattering of 6He ＋ p at 82.3 MeV/nucleon

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Chinese Physics Letters 2010年第9期27卷 65-68页

作者： FAISAL Jamil-Qureshi 楼建玲叶沿林曹中鑫江栋兴郑涛华辉李智焕李湘庆葛愉成庞丹阳李奇特肖军吕林辉乔锐游海波陈瑞九卢飞 Sakurai H Otsu H Nishimura M Sakaguchi S Baba H togano Y Yoneda K 李琛王硕王赫李阔昂 Nakamura t Nakayama Y Kondo Y Deguchi S satou Y tshoo K H School of Physics and State Key Laboratory of Nuclear Physics and technology Peking University Beijing 100871 RIKEN 2-1Hirosawa Wako Saitama 351-0198 Japan Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 Department of Physics Tokyo Institute of Technology Japan School of Physics Seoul NationM University Korea

Differential cross sections for the elastic scattering of halo nucleus 6He on proton target were measured at 82.3 MeV/u. the experimental results axe well reproduced by optical model calculations using global potential KD02 with a reduction of the depth of real volume part by a factor of 0.7. A systematic analysis shows that this behavior might be related to the weakly bound property of unstable nuclei.

关键词： Measurement