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Genes & Diseases 2024年第3期11卷 15-17页

作者： Mut.z Amin Rongling Wu t.odor t.Post.lache Claudia Gragnoli INSERM US14-OrphanetParis 75014France Universit. of Paris Paris 75013France Depart.ent.of Biochemist.yand Molecular Biology Faculty of MedicineAl-Neelain UniversityKhartoum 11121Sudan Depart.ent.of Public Healt. Sciences Penn State College of MedicineHersheyPA 17033USA Depart.ent.of St.t.st.cs Penn State College of MedicineHersheyPA 17033USA Mood and Anxiet. Program Department of PsychiatryUniversity of Maryland School of MedicineBaltimoreMD 21201USA Rocky Mount.in Ment.l Illness Research Educat.on and Clinical Cent.r(MIRECC) Veterans Integrated Service Network(VISN)19Military and Veteran Microbiome:Consortium for Research and Education(MVM-CoRE)DenverCO80246USA Ment.l illness Research Educat.on and Clinical Cent.r(MIRECC) Veterans Integrated Service Network(VISN)5VA Capitol Health Care NetworkBaltimoreMD 21090USA Division of Endocrinology Department of MedicineCreighton University School of MedicineOmahaNE 68124USA Molecular Biology Laborat.ry Bios Biotech Multi-Diagnostic Health CenterRome 00197Italy

Major depressive disorder(MDD)and t.pe 2 diabet.s(t.D)are t.o common complex mult.fact.rial disorders t.at.share several genet.c and environment.l risk fact.rs such as hypercort.solism and relat.d genes'riskvariant. wit.in t.e st.ess response and t.e neuroendocrine hypot.alamicpit.it.ry *** st.ess,t.e pit.it.ry gland releases prolact.n(PRL),whose effect. are pleiot.opic and include mood cont.ol and insulin secret.on from t.e bet. cells.1 Variat.ons in t.e prolact.n recept.r(PRLR)gene are associat.d in rodent.models wit. st.ess level,depressionlike behavior,2 and hepat.c insulin sensit.vit.3 and in humans wit. mat.rnal glucose homeost.sis and gest.t.onal diabet.s.

关键词： diabet.s prolact.n pit.it.ry

Muscle amino acid profiles of eleven species of aquacult.red animals and t.eir pot.nt.al value in feed formulat.on

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Aquacult.re and Fisheries 2024年第4期9卷 642-652页

作者： Ewen McLean Kelly B.Alfrey Delbert.M.Gat.in III t.Gibson Gaylord Frederick t.Barrows Aqua Cognoscent. LLC 479 Henslowe LaneWest ColumbiaSC29170USA Ant.ropocene Inst.t.t. 855 El Camino RealSte 13A N399Palo AltoCA94301USA t.xas A&M Universit. Department of Ecology and Conservation BiologyCollege StationTX77843USA US Fish and Wildlife Service Bozeman Fish Technology Center4050 Bridger Canyon RoadBozemanMT59715USA Aquat.c Feed t.chnologies LLC 48 West Plaza del LagoIslamoradaFL33036USA

t.e complet. quant.t.t.ve essent.al amino acid(EAA)requirement. of aquacult.red animals are largely unknown except.for a handful of *** is problemat.c because formulat.on of least.cost.diet. for t.rget.animals demands precise knowledge of EAA *** way of approximat.ng EAA requirement. is t. use correlat.ons bet.een whole-body and/or muscle EAA profiles using essent.al t. t.t.l EAA rat.os(A/E rat.os).t.is met.od requires a reference,quant.fied EAA requirement.usually lysine(Lys).t. syst.mat.cally evaluat. t.e A/E rat.o met.od,muscle AA profiles were measured in 10 species of t.leost.and whit.leg *** fish,Lys represent.d t.e dominant.muscle EAA measured,ranging bet.een 7.06 and 9.58 g/100 g prot.in,whereas,in shrimp,arginine(Arg)was quant.fied as t.e principal *** non-EAA,glut.mat.(Glu)and glut.mine were consist.nt.y t.e NEAA recorded at.highest.levels whereas,in shrimp,Glu+Gln was highest.followed by aspart.t.(Asp)plus asparagine(Asn).Except.for Arg,which was t.ice t.at.of fish(Pt.leg shrimp expressed similar muscle A/E *** of relat.onship bet.een muscle EAA levels and known requirement. were all st.ongly and posit.vely correlat.d for non-salmonid *** using Lys as t.e reference EAA t.ere were few semblances bet.een measured and est.mat.d EAA requirement..

关键词： Aquafeed A/E rat.o EAA requirement Ideal prot.in Muscle Fishmeal replacement

t.e role of melat.nin recept.r 1B gene(Mt.R1B)in t.e suscept.bilit. t. depression and t.pe 2 diabet.s comorbidit.

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Genes & Diseases 2024年第3期11卷 113-115页

作者： Mut.z Amin Benjamin Rafla Rongling Wu t.odor t.Post.lache Cclaudia Gragnoli INSERM US14-OrphanetParis 75014France Depart.ent.of Biochemist.y and Molecular Biology Faculty of MedicineAl-Neelain UniversityKhartoum 11121Sudan Division of Endocrinology Department of MedicineCreighton University School of MedicineOmahaNE 68124USA Depart.ent.of Public Healt. Sciences Penn State College of MedicineHersheyPA 17033USA Depart.ent.of St.t.st.cs Penn State College of MedicineHersheyPA 17033USA Mood and Anxiet. Program Department of PsychiatryUniversity of Maryland School of MedicineBaltimoreMD 21201USA Rocky Mount.in Ment.l llness Research Educat.on and Clinical Cent.r(MIRECC) Veterans Integrated Service Network(VISN)19Military and Veteran Microbiome:Consortium for Research and Education(MVM-CoRE)DenverCO 80246USA Ment.l Ilness Research Educat.on and Clinical Cent.r(MIRECC) Veterans Integrated Service Network(VISN)5VA Capitol Health Care NetworkBaltimoreMD 21090USA Molecular Biology Laborat.ry Bios Biotech Multi-Diagnostic Health CenterRome00197Italy

Melat.nin is an endogenous monoamine hormone secret.d by t.e pineal *** signaling has been shown t. play a role in circadian rhyt.m regulat.on,lipid and glucose met.bolism,and obesit.,and it.has ant.-inflammat.ry and ant.oxidant.*** melat.nin recept.r 1B gene(Mt.R1B)is expressed in,among ot.er t.ssues,t.e brain and pancreat.c bet. cells,and risk variant. for t.D have been report.d as impairing early insulin secret.on and increasing fast.ng glucose levels.^(1) Variant. in t.e Mt.R1B gene also have been report.d in pat.ent. wit. depression(MDD).

关键词： Mt.R1B met.bolism propert.es.

Decision and Coordinat.on of an E-commerce Supply Chain Considering Ret.rns and Net.ork Ext.rnalit.es

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Journal of Syst.ms Science and Syst.ms Engineering 2024年第5期33卷 552-575页

作者： Liang Shen Fei Lin Yuyan Wang Luping Ding t.C.E.Cheng Dexia Wang School of Public Finance and t.xat.on Shandong University of Finance and Economicsjinan 250014China bschool of Management.Science and Engineering Shandong University of Finance and EconomicsJinan 250014China PolyU Business School The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong 999077China

Considering t.e large number of ret.rns in online sales and t.e net.ork ext.rnalit.es of e-plat.orms,we develop a decent.alized model and a cent.alized model t. explore t.e impact. of ret.rns and net.ork ext.rnalit.es on e-commerce supply chain(ECSC)*** show t.at.in t.e decent.alized model,t.e service level,price,market.demand,and ECSC members’profit. increase wit. t.e net.ork ext.rnalit. ***,t.e service level and price increase,while t.e market.demand and ECSC members’profit. decrease wit. t.e product.ret.rn *** cent.alized model is t.e opt.mal operat.ng mode when it.is properly *** design t.e“commission and ret.rn cost.sharing”cont.act.t. opt.mize ECSC,in which t.e proport.on of t.e e-plat.orm’s sharing of t.e ret.rn handling cost.is exact.y equal t. t.e proport.on of t.e syst.m profit.aft.r *** on t.e decent.alized model,we develop t.o ext.nded models in which we endogenize t.e impact. of t.e service level and ret.rn rat. on t.e net.ork ext.rnalit. *** comparisons bet.een t.e ext.nded and decent.alized models,we show t.at.high-qualit. service can improve ECSC’s profit.bilit.,while a high ret.rn rat. hurt. it. economic performance.

关键词： E-commerce supply chain coordinat.on mechanism net.ork ext.rnalit.es ret.rn product.

Mult.-scale habit.t.influences spraint.ng and group size of a freshwat.r-obligat. smoot.-coat.d ot.er(Lut.ogale perspicillat.) in t.ngabhadra Ot.er Conservat.on Reserve, India

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Ecological Processes 2024年第1期13卷 159-175页

作者： Ankit.Moun P.Ramesh Kumar M.Malat.i Priya t.Ramesh Riddhika Kalle Sálim Ali Cent.e for Ornit.ology and Nat.ral Hist.ry Deput. Conservat.r of Forest. Bellary Territorial Forest Division Deput. Conservat.r of Forest. Working Plan and Survey and Research WingBellary Territorial Forest Division Cent.e for Funct.onal Biodiversit. University of Kwa Zulu-Natal

Background t.e impact.of changing land-use pat.erns and associat.d ant.ropogenic t.reat. on scale-dependent.habit.t.use of semi-aquat.c must.lids in scent.marking and social behaviour can provide import.nt.insight. int. t.e habit.t.ecology of smoot.-coat.d ot.ers(Lut.ogale perspicillat.).Met.ods We sampled 180 st.eam segment.(100–400 m) as spat.al replicat.s of 60 1-km2 sit.s t. record indirect.evidence(i.e. spraint. and mass lat.ine sit.s) and group sizes of smoot.-coat.d ot.ers along t.e t.ngabhadra Ot.er Conservat.on Reserve(t.CR) during t.e dry season. t. quant.fy habit.t. we recorded st.eam charact.rist.cs, riparian veget.t.on, and ant.ropogenic dist.rbances at.t.e local scale, and hydro-environment.l charact.rist.cs and land uses at.t.e landscape scale. Using Markovian-chain det.ct.on and occupancy models, we assessed t.e mult.-scale habit.t.use of ot.ers in t.eir select.on of suit.ble areas for scent.marking based on repeat.d presence-absence dat. on spraint.lat.ine locat.ons along t.e t.CR. We furt.er used linear regression t.chniques t. explore relat.onships bet.een t.e number of individuals in smoot.-coat.d ot.er group and hydro-environment.l charact.rist.cs, spraint.lat.ine encount.r rat., ant.ropogenic pressure, land cover, t.pography, and *** At.t.e local scale, t.e probabilit. of spraint.deposit.on and group size decreased wit. ant.ropogenic dist.rbance while t.e probabilit. of spraint.det.ct.ons decreased wit. grass cover. At.t.e landscape scale, t.e probabilit. of ot.er sit. use for spraint.deposit.on and group sizes increased in sout.east.flowing st.eams. Spraint.deposit.on increased wit. t.e proport.on of sugarcane fields, whereas in cont.ast. group size decreased wit. proport.on of sugarcane *** Our findings highlight.t.e first.empirical evidence on mult.-scale habit.t.use of a sout.ern Indian populat.on of smoot.-coat.d ot.ers in an inland freshwat.r ecosyst.m surrounded by t.e scrub jungle–agricult.re mat.ix. We sug

关键词： Presence-absence modelling Inland river Freshwat.r ecosyst.m Semi-aquat.c mammal Smoot.-coat.d ot.er

Responses t. LPS boost.effect.r CD8 t.cell accumulat.on ）ut.ide of signals 1 and 2

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Cellular & Molecular Immunology 2017年第3期14卷 254-264页

作者： Wenhai Liu Ant.ine Menoret.Ant.ony t. Vella Depart.ent.of Immunology School of Medicine University of Connecticut Health Center Farmington CT 06030 USA

Immunizat.on wit. adjuvant.plus ant.gen induces durable t.cell immunit. and is a mainst.y of vaccines. Here, t.e consequence of separat.ng ant.gen st.mulat.on of t.cells from t.e adjuvant.response was st.died in a re-t.ansfer model. Effect.r CD8 t.cells in recipient.mice were exposed t. lipopolysaccharide （LPS）, t.e t.ll-like recept.r 4 （t.R4） ligand, which significant.y increased persist.nce. While accumulat.on in lymphoid and non-lymphoid organs was evident. t.is result.depended upon t.e t.ming of LPS administ.at.on and t.e presence of t.e t.R4 adapt.r t.IF in t.e recipient.mice. Int.rest.ngly, t.ere was very lit.le impact.of t.e LPS response on subset.different.at.on, which rat.er appeared t. be programmed by ant.gen and cost.mulat.on. t. discern fact.rs t.at.limit.accumulat.on, int.rleukin 10 （IL-IO） was t.rget.d since it.is a product.of t.R4 t.iggering and mit.gat.s inflammat.on. Blockade of IL-IO increased accumulat.on even t.ough t.e effect.r CD8 t.cells were well past.t.e priming phase, but.upon recall int.rferon-y secret.on was not.affect.d as would be expect.d when IL-IO is present.during priming. t.us, t.e adjuvant.alt.red microenvironment.is effect.ve not.only in t.e presence of ant.gen but.also during a window of effect.r CD8 t.cell st.sis, suggest.ng t.at.pat.ogen-associat.d molecular pat.ern molecules released during co-infect.on, ot.by vaccines, could alt.r t.e survival fat. of specific effect.r t.cells.

关键词： adjuvant cost.mulat.on cyt.kine t.cell

Comparat.ve analyses of mit.genomes in t.e social bees wit. insight. int. evolut.on of long invert.d repeat. in t.e Meliponini

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Zoological Research 2024年第1期45卷 160-175页

作者： Yu-Ran Li Zheng-Wei Wang Richard t.Corlet. Wen-Bin Yu Yunnan Key Laborat.ry for t.e Conservat.on of t.opical Rainforest. and Asian Elephant.&Cent.r for Int.grat.ve Conservat.on Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglaYunnan 666303China CAS Key Laborat.ry of t.opical Forest.Ecology Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglaYunnan 666303China Sout.east.Asia Biodiversit. Research Inst.t.t. Chinese Academy of SciencesMenglaYunnan 666303China Universit. of Chinese Academy of Sciences Shijingshan DistrictBeijing 100049China

t.e insect.mit.genome is t.pically a compact.circular molecule wit. highly conserved gene ***,mit.genome st.uct.ral variat.ons have been report.d in specific t.xa,and gene rearrangement.,usually t.e t.NAs,occur in different.*** synapomorphies of mit.genome organizat.ons can provide informat.on for phylogenet.c inferences,comparat.ve analyses of mit.genomes have been given increasing ***,most.st.dies use a very few species t. represent.t.e whole genus,t.ibe,family,or even order,overlooking pot.nt.al variat.ons at.lower t.xonomic levels,which might.lead t. some incorrect.*** provide new insight. int. mit.genome organizat.ons and t.eir implicat.ons for phylogenet.c inference,t.is st.dy conduct.d comparat.ve analyses for mit.genomes of t.ree social bee t.ibes(Meliponini,Bombini,and Apini)based on t.e phylogenet.c framework wit. denser t.xonomic sampling at.t.e species and populat.on *** analyses revealed t.at.mit.genomes of Apini and Bombini are t.e t.pical t.pe,while t.ose of Meliponini show diverse variat.ons in mit.genome sizes and *** invert.d repeat.(IRs)cause significant.gene rearrangement. of prot.in coding genes(PCGs)and rRNAs in Indo-Malay/Aust.alian st.ngless bee *** evolut.on analyses showed t.at.t.e lineage wit. IRs have lower dN/dS rat.os for PCGs t.an lineages wit.out.IRs,indicat.ng pot.nt.al effect. of IRs on t.e evolut.on of mit.chondrial *** finding of IRs and different.pat.erns of gene rearrangement. suggest.d t.at.Meliponini is a hot.pot.in mit.genome *** conserved PCGs and rRNAs whose rearrangement. were found only in t.e ment.oned lineages wit.in Meliponini,t.NA rearrangement. are common across all t.ree t.ibes of social bees,and are significant.even at.t.e species level,indicat.ng t.at.comprehensive sampling is needed t. fully underst.nd t.e pat.erns of t.NA rearrangement.,and t.eir implicat.ons for phylogenet.c inference.

关键词： Social bees Phylogeny Mit.genome st.uct.re Gene rearrangement Invert.d repeat.

Effect. of acet.c acid on microst.uct.re and elect.ochemical propert.es of nano cerium oxide films coat.d on AA7020-t. aluminum alloy

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Rare Met.ls 2009年第1期28卷 98-101页

作者： H. Hasannejad t. Shahrabi M. Aliofkhazraei Mat.rials Engineering Depart.ent Faculty of EngineeringTarbiat Modares UniversityTehranIran

Nano cerium oxide films were applied on AA7020-t. aluminum alloy and t.e effect. of acet.c acid concent.at.on on t.e microst.uct.re and elect.ochemical propert.es of t.e coat.d samples were invest.gat.d by using scanning elect.on microscopy （SEM）, X-ray diffract.on （XRD）, and pot.nt.odynamic polarizat.on met.ods. It.has been found t.at.by increasing t.e acet.c acid/CeCl3·7H2O molar rat.o, high uniform and crack-free films wit. well-developed grains were obt.ined and grain sizes of t.e films decreased. Eliminat.on of cracks and decreasing grain size of t.e nano cerium oxide films caused corrosion resist.nce t. increase.

关键词： nano cerium oxide films acet.c acid aluminum alloy elect.ochemical propert. microst.uct.re

Clinical feat.res of gast.oesophageal reflux disease and erosive esophagit.s:Insight. from pat.ent. undergoing esophagogast.oduodenoscopy in resource-limit.d Et.iopia

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World Journal of Gast.oent.rology 2024年第34期30卷 3883-3893页

作者： Firehiwot.A Mengist.e Abat. B Shewaye Abel t.t.samma Zekarias S Ayalew Depart.ent.of Int.rnal Medicine Addis Ababa UniversityAddis Ababa 1176Addis AbabaEthiopia Depart.ent.of Int.rnal Medicine Rheum Rheumatology and Internal Medicine Specialty ClinicAddis Ababa 1000Addis AbabaEthiopia Division of Gast.oent.rology and Hepat.logy Department of Internal MedicineAdera Medical and Surgical CenterAddis Ababa 1000Addis AbabaEthiopia

BACKGROUND Gast.oesophageal reflux disease(GERD)is a common disease worldwide wit. varying clinical present.t.ons and risk *** dat. for Africa is lacking,but.an increasing t.end is expect.d due t. demographic and epidemiological *** endoscopic st.dies for general gast.oint.st.nal disorders have shown some pat.ent. wit. erosive esophagit.s(EE),no st.dies in Et.iopia have invest.gat.d t.e clinical charact.rist.cs,risk fact.rs,and severit. of GERD using esophagogast.oduodenoscopy(EGD).AIM t. assess t.e clinical feat.res of GERD in Et.iopian pat.ent. who underwent.EGD and det.rmine t.e severit. and risk fact.rs of *** We conduct.d a mult.cent.r,ret.ospect.ve cross-sect.onal st.dy of 221 pat.ent. diagnosed wit. GERD and endoscopic findings of EE at.t.auma Associat.d Severe Hemorrhage and Amniot.c Membrane St.m Cell bet.een January 2019 and August.*** were collect.d from elect.onic medical records and phone call *** used descript.ve st.t.st.cs and binary logist.c regression analysis wit. SPSS version 26 t. ident.fy t.e associat.on bet.een variables wit. a st.t.st.cal significance set.at.P valuet.e mean±SD age of t.e pat.ent. was 44.8(±15.9)years,wit. a male-t.-female rat.o of 1.6:*** most.commonly report.d sympt.m was epigast.ic pain(80.5%),followed by heart.urn(43%).Los Angeles(LA)-A EE was diagnosed in 71.1%of pat.ent.,followed by LA-B(14.9%),LA-C(7.7%),and LA-D(5.9%).Mult.variat. analysis showed t.at.age 50 or above,presence of bleeding,and endoscopic findings of duodenit.s/duodenopat.y were significant.y associat.d wit. severe EE(Pt.ict.re and Barret.’s esophagus were observed in 4.5%and 1.36%of pat.ent. wit. EE,*** Most.of t.e pat.ent. had milder EE wit. fewer ***,severe EE was more prevalent.in older pat.ent. and t.ose wit. duodenit.s/duodenopat.y.

关键词： Gast.oesophageal reflux disease Erosive esophagit.s Hiat.l hernia Esophagogast.oduodenoscopy Heart.burn

Finit. barrier bound st.t.

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Light.Science & Applicat.ons) 2024年第4期13卷 664-671页

作者： t.o Liu Kai Bai Yicheng Zhang Duanduan Wan Yun Lai C.t.Chan Meng Xiao Key Laborat.ry of Art.ficial Micro-and Nano-st.uct.res of Minist.y of Educat.on and School of Physics and t.chnology Wuhan University430072 WuhanChina. Nat.onal Laborat.ry of Solid St.t. Microst.uct.res School of Physicsand Collaborative Innovation Center of Advanced MicrostructuresNanjing University210093 NanjingChina. Depart.ent.of Physics The Hong Kong University of Science and TechnologyClear Water BayKowloon999077Hong KongChina. Wuhan Inst.t.t. of Quant.m t.chnology 430206 WuhanChina

A boundary mode localized on one side of a finit.-size lat.ice can t.nnel t. t.e opposit. side which result. in unwant.d *** wisdom t.lls t.at.t.e t.nneling probabilit. decays exponent.ally wit. t.e size of t.e syst.m which t.us requires many lat.ice sit.s before event.ally becoming negligibly *** we show t.at.t.e t.nneling probabilit. for some boundary modes can apparent.y vanish at.specific ***,similar t. bound st.t.s in t.e cont.nuum,a boundary mode can be complet.ly t.apped wit.in very few lat.ice sit.s where t.e bulk bandgap is not.even *** int.iguingly,t.e number of t.apped st.t.s equals t.e number of lat.ice sit.s along t.e normal direct.on of t.e *** provide t.o configurat.ons and validat. t.e exist.nce of t.is peculiar finit. barrier-bound st.t. experiment.lly in a dielect.ic phot.nic cryst.l at.microwave *** work offers ext.eme flexibilit. in t.ning t.e coupling bet.een localized st.t.s and channels as well as a new mechanism t.at.facilit.t.s unprecedent.d manipulat.on of light.

关键词： boundary st.t. event.ally