检索结果-南通市图书馆

Vibrio *** Macrobrachium amazonicum prawn farming are inhibited by Moringa oleifera extracts

Asian Pacific Journal of Tropical Medicine 2015年第11期8卷 899-902页

作者： Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Celia Maria de Souza Sampaio Francisco Geraldo Barbosa Manoel de araujo Neto Paiva Glaucia Morgana de Melo Guedes Lucas Pereira de Alencar Yago Brito de Ponte Tereza de Jesus Pinheiro Gomes Bandeira Jose Luciano Bezerra Moreira debora de Souza Collares Maia Castelo-Branco Waldemiro de Aquino Pereira-Neto Rossana de Aguiar Cordeiro Jose Julio Costa Sidrim Marcos Fabio Gadelha Rocha department of Pathology and Legal Medicine Postgraduate Program in Medical MicrobiologySpecialized Medical Mycology CenterFederal University of Ceara School of Veterinary Medicine Postgraduate Program in Veterinary SciencesState University of Ceara department of Organic and Inorganic Chemistry Federal University of Ceara

Objective:To investigate the in vitro antimicrobial potential of extracts of stem,leaves,flowers,pods and seeds of Moringu okifera(***) against Vibrio *** hatchery water and the prawn Mmrobrachium ***:The ethanol extracts of stem,leaves,pods and seeds and chloroform extract of flowers of *** were tested against Vibrio cholerue(***) serogroups non-O1/non-O139(n=4).Vibrio vulnificus(n=l) and Vibrio mimicus(n=1).Escherichia coli(***)(ATCC(?) 25922) was used as quality *** species were obtained from Macmbrachium amazonicum prawns and from hatchery water from prawn *** Minimum Inhibitory Concentration(MIC) was determined by broth microdilution ***:The best result was obtained with the ethanol extract of pods,which inhibited three strains of the ***,Vibrio vulnificus,Vibrio minimis and ***(MIC range 0.312-5.000 mg/mL).The chloroform extract of flowers was effective against all *** strains and ***(MIC range 0.625-1.250 mg/mL).However,the ethanol extracts of stem and seeds showed low effectiveness in inhibiting the bacterial ***:The extracts of pods,flowers and leaves of *** have potential for the control of Vibrio *** studies are necessary to isolate the bioaetive compounds responsible for this antimicrobial activity.

关键词： Prawn Macrobrachium amazonicum Moringa oleifera Vi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Consolidation of soft clay foundation improved by geosyntheticreinforced granular columns:Numerical evaluation

引用

Journal of Rock Mechanics and Geotechnical Engineering 2021年第5期13卷 1173-1181页

作者： Nima R.Alkhorshid Gregório L.S.araujo Ennio M.Palmeira Institute of Integrated Engineering Federal University of Itajubáe Itabira CampusItabiraMinas Gerais35903-087Brazil department of Civil and Environmental Engineering University of BrasíliaBrasíliaDistrito Federal70910-900Brazil

Soft clays are problematic soils as they present high compressibility and low shear *** are several methods for improving in situ conditions of soft *** on the geotechnical problem’s geometry and characteristics,the in situ conditions may require reinforcement to restrain instability and construction *** columns reinforced by geosynthetic material are widely used to reduce settlements of embankments on soft *** also accelerate the consolidation rate by reducing the drainage path’s length and increasing the foundation soil’s bearing *** this study,the performance of encased and layered granular columns in soft clay is investigated and *** numerical results show the significance of geosynthetic stiffness and the column length on the embankment ***,the results show that granular columns may play an important role in dissipating the excess pore water pressures and accelerating the consolidation settlements of embankments on soft clays.

关键词： Geosynthetic Embankment Granular column Consolidation Soft soil

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characterization of Cnidoscolus quercifolius Pohl bark root extract and evaluation of cytotoxic effect on human tumor cell lines

引用

Asian Pacific Journal of Tropical Biomedicine 2018年第7期8卷 345-351页

作者： Paulo Fernando Machado Paredes Selene Maia de Morais Fernando Cesar Rodrigues Brito Luiz Francisco Wemmenson Goncalves Moura Patricia de araujo Rodrigues Stephen Rathinaraj Benjamin Francisco Ernani Alves Magalhaes Eridan Orlando Pereira Tramontina Florean Maria Izabel Florindo Guedes Northeast Biotechnology Network Graduate Program of Biotechnology State University of Ceara Itaperi campus department of Chemistry State University of Ceara Itaperi campus Laboratory of Bioprospecting of Natural Products and Biotechnology State University of CearaCECITEC

Objective: To evaluate the chemical components of active extract from Cnidoscolus quercifolius root bark and its cytotoxic potential against several tumor strains. Methods: The high-performance liquid chromatography with diode-array detection and ~1H and ^(13)C nuclear magnetic resonance spectroscopy of the extract were used to distinguish the existence of possible functional groups in the root bark extract. The in vitro cytotoxic activity of methanol extract on human colon cancer cell lines was evaluated using OVCAR-8, SF-295, HCT-116, HL-60 strains and the samples were assessed by 3-(4,5-dimethylthiazol2-yl)-2,5-diphenyltetrazolium bromide method. Results: The analysis of nuclear magnetic spectra of the active chloroform fraction revealed the presence of absorptions bands correspondent to a mixture of favelines such as neofavelanone, deoxofaveline or methyl-faveline, which structures were confirmed by ultraviolet spectra upon high-performance liquid chromatography with diode-array detection analysis. The active fraction showed cytotoxic effects in the tested strains, HCT-116, SF-295, OVCAR-8 and HL-60 cells with IC_(50) of 72 hours ranging from 4.95 to 15.23 μg/mL. Conclusions: The results suggest that the substances present in faveleira(Cnidoscolus quercifolius) root bark extract have a cytotoxic potential against several tumor lines, showing a broader antitumour potential, and in addition no adverse to healthy cells. Therefore, the root bark extract of Cnidoscolus quercifolius has a possibility of use for anticarcinogenic therapies.

关键词： Cnidoscolus quercifolius Pohl. methyl-faveline deoxofaveline Neofavelanone Faveline Cytotoxicity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The role of extracellular calcium in the effect of a snake venom Lys49-phospholipase A_(2) on water transport across epithelial membranes

引用

Journal of Biophysical Chemistry 2011年第3期2卷 222-225页

作者： Renner de Souza Leite Wilson Franco Heloisa Sobreiro Selistre-de-araujo Unidade Academica de Saude do Centro de Educacao e Saude Universidade Federal de Campina GrandeCuiteParaíbaBrazil departamento de Ciencias Fisiologicas Universidade Federal de Sao CarlosSao CarlosBrazil

ACLMT is a Lys49-phospholipase A2 myotoxin isolated from the venom of the Agkistrodon contortrix laticinctus snake. This study investigated the mechanisms involved in effect of ACLMT on membrane water permeability by examining the role of extracellular calcium and strontium in this effect. Water flow across the membrane was gravimetrically measured in bladder sac preparations. The decrease in extracellular calcium promoted a higher response of epithelium to ACLMT, suggesting that the extracellular calcium protects the membrane from the action of the toxin. No alteration in the effect of the toxin on water transport was observed when calcium was replaced by strontium, indicating that this effect is independent of its enzymatic activity. These findings may bring an important contribution towards the comprehension of the mechanisms involved in the effect of Lys49-phospholipase A2 myotoxins on water permeability of epithelial membranes, with implications for the understanding of renal toxicity.

关键词： Epithelial Tissue Membrane Permeability Myotoxin Lys49-Phospholipase A_(2) Toad Bladder Water Transport

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Management of Innovation Process in Services： Micro and Small Enterprises of the Metropolitan Region of Campinas

引用

Management Studies 2017年第3期5卷 170-182页

作者： Tarik Veloso Dal Molin Luiz de Freitas Ayres Antonio Henriques de araujo Junior Merial Animal Health Ltda. Campinas Brazil Mackenzie Presbyterian University Campinas Brazil State University of Rio de Janeiro R J Brazil

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一种基于电荷法模型的亚阈值电流分析方法

引用

固体电子学研究与进展 1993年第1期13卷 9-13页

作者：牛国富汤庭鳌 Carlos A.Paz de araujo 复旦大学电子工程系 University of Colorado Colorado Springs Co 80933-7150USA

采用电荷法,避免使用有效沟道厚度的近似概念,较严格地讨论了MOS场效应管的亚阈值电流、亚阈值摆幅,其结果与实验数据符合较好。

关键词：亚阈值电流 MOS 场效应晶体管

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The hidden half comes into the spotlight: Peeking inside the black box of root developmental phases

引用

Plant Communications 2022年第1期3卷 36-52页

作者： Joao Antonio Siqueira Wagner C.Otoni Wagner L.araujo departamento de Biologia Vegetal Universidade Federal de Vic¸osaVic¸osaMG 36570-900Brazil

Efficient use of natural resources(e.g.,light,water,and nutrients)can be improved with a tailored developmental program that maximizes the lifetime and fitness of *** plant shoots,a developmental phase represents a time window in which the meristem triggers the development of unique morphological and physiological traits,leading to the emergence of leaves,flowers,and *** developmental phases in plant shoots have been shown to enhance food production in crops,this phenomenon has remained poorly investigated in *** light of recent advances,we suggest that root development occurs in three main phases:root apical meristem appearance,foraging,and *** provide compelling evidence suggesting that these phases are regulated by at least four developmental pathways:autonomous,non-autonomous,hormonal,and *** developmental pathways differentially coordinate organ plasticity,promoting morphological alterations,tissue regeneration,and cell death ***,we suggest how nutritional checkpoints may allow progression through the developmental phases,thus completing the root life *** insights highlight novel and exciting advances in root biology that may help maximize the productivity of crops through more sustainable agriculture and the reduced use of chemical fertilizers.

关键词： developmental transitions plasticity cell fates nutritional checkpoints root development root clock

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Amino Acid Catabolism in Plants

引用

Molecular Plant 2015年第11期8卷 1563-1579页

作者： Tatjana M. Hildebrandt Adriano Nunes Nesi Wagner L. araujo Hans-Peter Braun Institut fur Pfianzengenetik Leibniz Universitat Hannover Herrenhauser StraBe 2 30419 Hannover Germany departamento de Biologia Vegetal Universidade Federal de Vicosa Vicosa Minas Gerais 36570-900 Brazil

Amino acids have various prominent functions in plants. Besides their usage during protein biosynthesis, they also represent building blocks for several other biosynthesis pathways and play pivotal roles during signaling processes as well as in plant stress response. In general, pool sizes of the 20 amino acids differ strongly and change dynamically depending on the developmental and physiological state of the plant cell. Besides amino acid biosynthesis, which has already been investigated in great detail, the catabolism of amino acids is of central importance for adjusting their pool sizes but so far has drawn much less attention. The degradation of amino acids can also contribute substantially to the energy state of plant cells under certain physiological conditions, e.g. carbon starvation. In this review, we discuss the biological role of amino acid catabolism and summarize current knowledge on amino acid degradation pathways and their regulation in the context of plant cell physiology.

关键词： adenosine triphosphate amino acid catabolism carbon starvation energy metabolism enzyme regulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Is it possible to adopt the same oncological approach in urgent surgery for colon cancer?

引用

World Journal of Clinical Oncology 2022年第11期13卷 896-906页

作者： Bruno Yuki Yoshida Raphael L C araujo José Francisco M Farah Alberto Goldenberg Goldenberg department of Surgery Federal University of Sao PauloSao Paulo 04024-002Sao PauloBrazil department of General and Oncological Surgery Sao Paulo State Employee HospitalSao Paulo 04029-000Sao PauloBrazil

BACKGROUND Locoregional complications may occur in up to 30%of patients with colon *** they are frequent events in the natural history of this disease,there should be a concern in offering an oncologically adequate surgical treatment to these *** To compare the oncological radicality of surgery for colon cancer between urgent and elective *** One-hundred and eighty-nine consecutive patients with non-metastatic colon adenocarcinoma were studied over two years in a single institution,who underwent surgical resection as the first therapeutic approach,with 123 elective and 66 urgent *** assessment of oncological radicality was performed by analyzing the extension of the longitudinal margins of resection,the number of resected lymph nodes,and the percentage of surgeries with 12 or more resected lymph *** clinicopathological variables were compared between the two groups in terms of sex,age,tumor location,type of urgency,surgical access,staging,compromised lymph nodes rate,differentiation grade,angiolymphatic and perineural invasion,and early *** There was no difference between the elective and urgency group concerning the longitudinal margin of resection(average of 6.1 in elective vs 7.3 cm in urgency,P=0.144),number of resected lymph nodes(average of 17.7 in elective vs 16.6 in urgency,P=0.355)and percentage of surgeries with 12 or more resected lymph nodes(75.6%in elective vs 77.3%in urgency,P=0.798).It was observed that the percentage of patients aged 80 and over was higher in the urgency group(13.0%in elective vs 25.8%in urgency,P=0.028),and the early mortality was 4.9%in elective vs 15.2%in urgency(P=0.016,OR:3.48,95%CI:1.21–10.06).Tumor location(P=0.004),surgery performed(P=0.016)and surgical access(P<0.001)were also different between the two *** was no difference in other clinicopathological variables *** Oncological radicality of colon cancer surgery may be achieved in both emergency and

关键词： Colorectal cancer Intestinal obstruction Intestinal perforation Surgical oncology Lymph node excision

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Recurrence-free survival as a putative surrogate for overall survival in phase Ⅲ trials of curative-intent treatment of colorectal liver metastases:Systematic review

引用

World Journal of Clinical Oncology 2017年第3期8卷 266-272页

作者： Raphael LC araujo Paulo Herman Rachel P Riechelmann department of Upper Gastrointestinal and Hepato-Pancreato-Bliliary Sugery Barretos Cancer Hospital department of Gastroenterology University of S?o Paulo Instituto do Cancer do Estado de S?o Paulo Universidade de S?o Paulo

AIM To verify whether recurrence-free survival(RFS) surrogates overall survival(OS) in phase Ⅲ trials for resectable colorectal liver metastases(CRLM).METHODS MEDLINE,EMBASE,and Scopus databases were *** studies were phase Ⅲ trials testing any type of systemic therapy(neoadjuvant,adjuvant or perioperative) added to surgery in patients with resectable CRLM.A linear regression model based on hazard ratios(HR) of OS and RFS was *** Of 3059 studies,5 phase Ⅲ trials(1162 patients) were included for analyses.A linear regression weighted by each trial was used to estimate the association between each HR and *** originated formula was:OS HR =(0.93 × RFS HR) + 0.14;with RFS 95%CI(0.48-1.38),with P = *** This association suggests that RFS could work as a putative surrogate endpoint of OS in this population,avoiding bigger,longer and more resource-consuming *** OS could be assumed based on RFS and our model could be useful to better estimate sample size calculations of phase Ⅲ trials of CRLM aiming for OS.

关键词： Colorectal liver metastases Surgery Chemotherapy Clinical trial Long-term outcomes Surrogate endpoints

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：