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Successful outcomes of EMR-L with 3D-EUS for rectal carcinoids compared with historical controls

World Journal of Gastroenterology 2008年第25期14卷 4054-4058页

作者： Tsuyoshi Abe Tadayoshi Kakemura sumio fujinuma Iruru Maetani Division of Gastroenterology Department of Internal Medicine Toho University Ohashi Medical Center

AIM: To assess the results of endoscopic mucosal re-section with a ligation device (EMR-L) combined with three dimensional endoscopic ultrasonography (3D-EUS) using an ultrasonic probe for rectal carcinoids. In addition, diagnosis of the depth and size of lesions by EUS was evaluated. METHODS: Between January 2003 and March 2007, 20 patients underwent EMR-L with 3D-EUS using an ultrasonic probe (group A). 3D-EUS was combined with EMR-L at the time of injection of sterile physiological saline into the submucosal layer. For comparison, 14 rectal carcinoids that had been treated by EMR-L with-out 3D-EUS between April 1998 and December 2002 were evaluated as historical controls (group B). EUS was conducted for all of the patients before treatment to evaluate tumor diameter and depth of invasion. The percentage of complete resection and the verti-cal resection margin were compared between the two groups. RESULTS: The depth of invasion upon histopathologi-cal examination was in complete agreement with the pre-operative fi ndings by EUS. The tumor diameter de-termined by EUS approximated that found in the tissue samples. There were no signifi cant differences in the gender, tumor sites or tumor diameters between the two groups. The rate of complete resection for groups A and B was 100% and 71%, respectively (P < 0.05). The vertical resection margin of group A was longer than that of group B. CONCLUSION: EMR-L is effective as an endoscopictreatment for rectal carcinoids. In combination with 3D-EUS, safe and complete resection is further as-sured.

关键词： Endoscopic mucosal resection with a ligation device Endoscopic therapy Endoscopic ultraso-nography Rectal carcinoids

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Efficacy of the revised Vienna Classification for diagnosing colorectal epithelial neoplasias

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World Journal of Gastroenterology 2009年第19期15卷 2351-2356页

作者： Kenji Tominaga sumio fujinuma Takuro Endo Yoshihisa Saida Kei Takahashi Iruru Maetani Division of Gastroenterology Department of Internal MedicineToho University Ohashi Medical Center2-17-6 OhashiMeguro-kuTokyo 153-8515Japan Third Department of Surgery Toho University Ohashi Medical Center2-17-6 OhashiMeguro-kuTokyo 153-8515Japan Department of Surgical Pathology Toho University Ohashi Medical Center2-17-6 OhashiMeguro-kuTokyo 153-8515Japan

AIM： To prospectively investigate the efficacy of the revised Vienna Classification for diagnosing colorectal epithelial neoplastic lesions in cold biopsy ***： Patients were selected for inclusion if they had colorectal epithelial lesions that were not considered suitable for direct endoscopic resection,These included colorectal polyps ≥ 10 mm and lesions suspected of being carcinomas capable of invading the colorectal submucosa or beyond, including strictures, based on the cold biopsies obtained from each lesion prior to resection. We investigated the relationship between diagnoses based on cold biopsy samples using the revised Vienna Classification and resected specimens of the same lesions, and the therapeutic implications of diagnoses made using the revised Vienna Classification. The same cold biopsy specimens were also examined using the Japanese Group Classification guidelines, and compared with the resected specimens of the same lesions for ***： A total of 179 lesions were identified. The sensitivity, specificity, positive and negativepredictive values of the revised Vienna Classification for distinguishing between intramucosal lesions and submucosal invasive carcinomas in cold biopsy specimens was 22.2%, 100%, 100%, and 71.4%,respectively, and for distinguishing between intramucosal lesions and those invading the submucosa or beyond was 59.7%, 100%, 100%, and 37.6%,respectively. The sensitivity, specificity, positive and negative predictive values of the Japanese Group Classification for distinguishing between intramucosal lesions and submucosal invasive carcinomas in cold biopsy specimens was 83.3%, 91.4%, 83.3%. and 91.4%, respectively, and for distinguishing between intramucosal lesions and those invading the submucosa or beyond was 95.1%, 91.4%, 97.9%, and 82.1%, respectively. A total of 137 of 144 carcinomas that had invaded the submucosa or beyond and three high-grade intraepithelial neoplasias were diagnosed as ＂carcinoma＂

关键词： Biopsy Cancer Colonoscopy Colorectalepithelial neoplasia Revised Vienna Classification

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Evaluation of excavation damaged zones(EDZs)in Horonobe Underground Research Laboratory(URL)

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 365-378页

作者： Koji Hata sumio Niunoya Kazuhei Aoyagi Nobukatsu Miyara Obayashi Corporation Technology Research InstituteTechnology DivisionKiyoseTokyo204-8558Japan Obayashi Corporation Nuclear Facilities DivisionSinagawaTokyo108-8502Japan Japan Atomic Energy Agency Horonobe Underground Research CenterHoronobeHokkaido098-3224Japan

Excavation of underground caverns,such as mountain tunnels and energy-storage caverns,may cause the damages to the surrounding rock as a result of the stress *** this influenced zone,new cracks and discontinuities are created or propagate in the rock ***,it is effective to measure and evaluate the acoustic emission(AE)events generated by the rocks,which is a small elastic vibration,and permeability *** authors have developed a long-term measurement device that incorporates an optical AE(O-AE)sensor,an optical pore pressure sensor,and an optical temperature sensor in a single multi-optical measurement probe(MOP).Japan Atomic Energy Agency has been conducting R&D activities to enhance the reliability of high-level radioactive waste(HLW)deep geological disposal *** a high-level radioactive disposal project,one of the challenges is the development of methods for long-term monitoring of rock mass ***,in January 2014,the long-term measurements of the hydro-mechanical behavior of the rock mass were launched using the developed MOP in the vicinity of 350 m below the surface at the Horonobe Underground Research *** measurement results show that AEs occur frequently up to 1.5 m from the wall during *** addition,hydraulic conductivity increased by 2e4 orders of *** analysis revealed that the hydraulic behavior of the rock mass affected the pore pressure fluctuations and caused *** on this,a conceptual model is developed to represent the excavation damaged zone(EDZ),which contributes to the safe geological disposal of radioactive waste.

关键词： Excavation damaged zone(EDZ) Optical sensor Long-term monitoring Acoustic emission(AE) Shaft sinking

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Ultrafast reorientation of the Néel vector in antiferromagnetic Dirac semimetals

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npj Computational Materials 2021年第1期7卷 1562-1568页

作者： Atsushi Ono sumio Ishihara Department of Physics Tohoku UniversitySendai 980-8578Japan

Antiferromagnets exhibit distinctive characteristics such as ultrafast dynamics and robustness against perturbative fields,thereby attracting considerable interest in fundamental physics and technological ***,it was revealed that the Néel vector can be switched by a current-induced staggered(Néel)spin-orbit torque in antiferromagnets with the parity-time symmetry,and furthermore,a nonsymmorphic symmetry enables the control of Dirac ***,the real-time dynamics of the magnetic and electronic structures remain largely ***,we propose a theory of the ultrafast dynamics in antiferromagnetic Dirac semimetals and show that the Néel vector is rotated in the picosecond timescale by the terahertz-pulse-induced Néel spin-orbit torque and other torques originating from magnetic *** reorientation accompanies the modulation of the mass of Dirac fermions and can be observed in real time by the magneto-optical *** results provide a theoretical basis for emerging ultrafast antiferromagnetic spintronics combined with the topological aspects of materials.

关键词： materials Dirac metals

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Computational Cavitation Flows at Inception and Light Stages on an Axial-Flow Pump Blade and in a Cage-Guided Control Valve

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Journal of Thermal Science 2007年第4期16卷 337-345页

作者： sumio SAITO MasahiroSHIBATA HideoFUKAE Eisuke OUTA Tokyo National College of Technology 1220-2 Kunugida-machiHachioji-shiTokyo 193-0997 Graduate student Graduate School of Science and EngineeringWaseda University Department of Mechanical Engineering Waseda UniversityOkubo 3-4-1Shinjyuku-ku Tokyo 1600072Japan

Cavitation flows induced around an axial-flow pump blade and inside a high pressure cage-type valve are simulated by a two-dimensional unsteady Navier-Stokes analysis with the simplest treatment of bubble dynamics. The fluid is assumed as a continuum of homogeneous dispersed mixture of water and vapor nuclei. The analysis is aimed to capture transient stages with high amplitude pressure change during the birth and collapse of the bubble especially at the stage of cavitation inception. By the pump blade analysis, in which the field pressure is moderate, cavitation number of the inception and locations of developed cavitation are found to agree with experimental results in a wide flow range between high incidence and negative incidence. In the valve flow analysis, in which the water pressure of 5MPa is reduced to 2MPa, pressure change responding to the bubble collapse between the vapor pressure lower than 1 KPa and the extreme pressure of higher than 104 KPa is captured through a stable computation. Location of the inception bubble and pressure force to the valve plug is found agree well with the respective experimental features.

关键词： Cavitation unsteady CFD hydrofoil control valve homogeneous mixture inception and collapse transient pressure

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Diagnosis of mild chronic pancreatitis (Cambridge classification):Comparative study using secretin injection-magnetic resonance cholangiopancreatography and endoscopic retrograde pancreatography

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World Journal of Gastroenterology 2008年第8期14卷 1218-1221页

作者： Masafumi Suyama Yoshihiro Kubokawa sumio Watanabe Department of Gastroenterology. Juntendo University 2-1-1 Hongo Bunkyo-ku Tokyo 113-8421 Japan

AIM： To investigate the usefulness of secretin injection- MRCP for the diagnosis of mild chronic pancreatitis.METHODS： Sixteen patients having mild chronic pancreatitis according to the Cambridge classification and 12 control subjects with no abnormal findings on the pancreatogram were examined for the diagnostic accuracy of secretin injection-MRCP regarding abnormal branch pancreatic ducts associated with mild chronic pancreatitis （Cambridge Classification）, using endoscopic retrograde cholangiopancreatography （ERCP） for comparison.RESULTS： The sensitivity and specificity for abnormal branch pancreatic ducts determined by two reviewers were respectively 55%-63% and 75%-83% in the head, 57%-64% and 82%-83% in the body, and 44%-44% and 72%-76% in the tail of the pancreas. The sensitivity and specificity for mild chronic pancreatitis were 56%-63% and 92%-92%, respectively. Interobserver agreement （K statistics） concerning the diagnosis of an abnormal branch pancreatic duct and of mild chronic pancreatitis was good to excellent.CONCLUSION： Secretin injection-MRCP might be useful for the diagnosis of mild chronic pancreatitis.

关键词： Magnetic resonance cnolangiopancreatography Endoscopic retrograde cholangiopancreatography Mild Chronic pancreatitis Diagnosis

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Direct Evidence for Lip Lip Interactions in Multi-Walled Carbon Nanotubes

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Nano Research 2008年第5期1卷 434-439页

作者： Chuanhong Jin Kazu Suenaga sumio Iijima Nanotube Research Center National Institute of Advanced Industrial Science and Technology(AIST)Tsukuba 305-8565Japan

The stability of open edged multi-walled carbon nanotubes has been investigated by using in situ high resolution transmission electron microscopy at elevated *** of inter-shell structures was experimentally observed for the first time and attributed to a robust interaction between adjacent concentric shells(so-called lip lip interaction).The fl uctuating behavior of the inter-shell structures suggests a mechanism by which the carbon atoms can pass in or out through the inter-shell edges during carbon nanotube growth or shrinkage processes.

关键词： Multi-walled carbon nanotubes lip lip interaction in situ transmission electron microscopy

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Characteristics of Tantalum Surface Treated by 6-Triethoxysilylpropylamino-1,3,5-Triazine-2,4-Dithiol Using XPS

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稀有金属材料与工程 2012年第S1期41卷 33-37页

作者： Hirahara Hidetoshi Aisawa sumio Narita Eiichi Mori Katuhito Graduate School of Engineering Iwate UniversityMoriokaIwate 0208551Japan

The characteristic of material surfaces has a vital status in its application,for instance,surface properties of materials play a decisive role in adhesion technology between different materials.A method called molecule adhesion technology which can successfully adhere different materials such as polymers,rubbers,metals and exhibit strong adhesion strength without any adhesive *** this work,the rare metal of tantalum surface treated by corona and a molecular adhesive(6-triethoxysilylpropylamino1,3,5-triazine-2,4-dithiols,TES)has been investigated to clarify the reaction mechanism between tantalum and *** structures of surfaces treated by corona and TES were also *** contains two functional groups:one is alkoxysilyl group which can react with the OH group linked tantalum formed by the corona discharge treatment;the other is dithiol triazinyl group reacted with many other *** tantalum,corona treated and TES treated surfaces situation were analyzed by X-ray photoelectron spectroscopy(XPS).The result shows that the functional structure of OH groups was formed after corona discharge process and TES can be successfully reacted on the tantalum *** research can be as a preparation work to achieve the tantalum and other materials adhesion by using molecule adhesion technology in the MEMS and NEMS electronic device fields.

关键词： tantalum surface functional structure XPS adhesion

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Partial melting behavior and thixoforming properties of extruded magnesium alloy AZ91 with and without addition of SiC particles with a volume fraction of 15%

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Journal of Materials Science & Technology 2018年第7期34卷 1149-1161页

作者： Yu-Shi Yi Yi Meng Dan-Qing Li sumio Sugiyama Jun Yanagimoto College of Materials Science and Engineering Chongqing University Chongqing 400044 China National Engineering Research Center for Magnesium Alloys Chongqing 400044 China Institute of Industrial Science The University of Tokyo Tokyo 153-8505Japan

A series of reheating-isothermal holding experiments and compression tests were conducted on pristine magnesium alloy AZ91 extruded by equal channel angular extrusion （ECAE） and SiC particles （a volume fraction of 15%） reinforced AZ91 composite （AZ91-SiCp） by regular extrusion. Dissolution of eutectic com- pounds and partial melting of the ct-Mg matrix occurred during the reheating of these materials. Spherical semisolid slurries of these materials were obtained when the reheating temperature and isothermal hold- ing time were 550℃ and 20 s, respectively. The presence of SiCp in AZ91-SiCp not only caused lower liquid fractions of semisolid slurries but also resulted in higher values of flow stress during semisolid compression tests. Both AZgl alloy and AZ91-SiCp composite exhibited better thixoforming properties at high temperatures. Segregation of SiCp did not occur during thixoforming of AZ91-SiCp composite after an isothermal holding at semisolid temperatures for 20 s.2018 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science ＆ Technology.

关键词： Semisolid forming Metal matrix composites Magnesium alloy Microstructural evolution

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Effects of heat treatment on the microstructures and mechanical properties of a new type of nitrogen-containing die steel

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International Journal of Minerals,Metallurgy and Materials 2012年第6期19卷 511-517页

作者： Jing-yuan Li Peng Zhao Jun Yanagimoto sumio Sugiyama Yu-lai Chen School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China Institute of Radar and Avionics Aviation Industry Corporation of China Suzhou 215151 China Institute of Industrial Science the University of Tokyo Tokyo 153-8505 Japan Engineering Research Institute University of Science and Technology Beijing Beijing 100083 China

Nitrogen can increase the strength of steels without weakening the toughness and improve the corrosion resistance at the same time. Compared with conventional nitrogen-free die steels, a new type of nitrogen-containing die steel was developed with many superior properties, such as high strength, high hardness, and good toughness. This paper focused on the effects of heat treatment on the microstruc- tures and mechanical properties of the new type of nitrogen-containing die steel, which were investigated by the optimized deformation process and heat treatment. Isothermal spheroidal annealing and high-temperature quenching as well as high-temperature tempering were ap- plied in the experiment by means of an orthogonal method after the steel was multiply forged. The mechanical properties of nitro- gen-containing die steel forgings are better than the standard of NADCA #207-2003.

关键词： die steels nitrogen heat treatment microstructure mechanical properties forgings

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