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McGill Brisbane Symptom Score for patients with resectable pancreatic head adenocarcinoma

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World Journal of Gastroenterology 2014年第34期20卷 12226-12232页

作者： Mohammed H Jamal suhail A R Doi A James Moser Sinziana Dumitra Jad abou Khalil Eve Simoneau Prosanto Chaudhury Adedayo A Onitilo Peter Metrakos Jeffrey S Barkun Hepato-biliary Pancreatic and Liver Transplant SurgeryMcGill University Health CenterMontreal QCH3A 1A1Canada Department of Surgery Kuwait Medical SchoolKuwait CityKuwait 24923Kuwait Clinical Epidemiology Unit School of Population HealthUniversity of QueenslandBrisbane QLD4006Australia Department of Surgery Harvard Medical SchoolBeth Israel Deaconess HospitalBostonMA 02215United States Marshfield Clinic Research Foundation Marshfield ClinicMarshfieldWI 54449United States Division of General Surgery Department of SurgeryRoyal Victoria HospitalQuébec H3A 1A1Canada

AIM:To evaluate the ability of the McGill Brisbane Symptom Score(MBSS)to predict survival in resectable pancreatic head adenocarcinoma(PHA)***:All PHA patients(n=83)undergoing pancreaticoduodenectomy at the McGill University Health Center,Quebec between 1/2001-1/2010 were *** related to patient and cancer characteristics,MBSS variables,and treatment were collected;univariable and multivariable survival analyses were *** obtained complete follow-up until February 2011 in all patients through the database of the provincial health insurance plan of *** unique health insurance numbers of these patients were used to retrieve information from this database which captures all billable clinical encounters,and ensures 100%actual survival ***:Median survival was 23 mo overall:45 mo for patients with low MBSS,17 mo for high MBSS(P=0.005).At twelve months survival was 83.3%(95%CI:66.6-92.1)vs 58.1%(95%CI:42.1-71.2)in those with low vs high MBSS,and24 mo survival was 63.8%(95%CI:45.9-77.1)and 34.0%(95%CI:20.2-48.2)*** the multivariate Cox model(stratified by chemotherapy),after addition of clinically meaningful covariates,MBSS was the variable with the strongest association with survival(HR=2.63;P=0.001).Adjuvant chemotherapy interacted with MBSS category such that only high MBSS patients accrued a *** univariate analysis we found a lower mortality in high MBSS but not low MBSS patients receiving adjuvant *** interaction variable,on Cox model,resulted in an adjusted mortality HR for the high MBSS(compared to low MBSS)of 4.14(95%CI:1.48-11.64)without chemotherapy and 2.11(95%CI:1.06-4.17)with ***:The MBSS is a simple prognostic tool for resectable *** categorization of patients according to the MBSS allows effective stratification of patients to guide therapy.

关键词： Pancreatic neoplasms Pancreatic adenocarcinoma Whi

Using an Adaptive Neuro-Fuzzy Inference System （AnFis） Algorithm for Automatic Diagnosis of Skin Cancer

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通讯和计算机（中英文版） 2011年第9期8卷 751-755页

作者： suhail M. Odeh Department of Computer Information Systems Bethlehem University Bethlehem 92248 Palestine

DOWN’s syndrome with Systemic Lupus Erythematosis:Never turn a blind eye

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Discussion of Clinical Cases 2019年第4期6卷 17-19页

作者： Saera suhail Kidwai Hoori Shehwar Department of Internal Medicine Fazaiya Ruth Pfau Medical CollegeKarachiPakistan Neurospinal and Medical Institute KarachiPakistan

Down’s syndrome(DS,Trisomy 21)with a prevalence of 1:8,000 live births is considered the most common genetic chromosomal disorder,with an extra full or partial copy of chromosome *** addition to physical and mental developmental delays and disabilities being a challenge to this disorder,vulnerability of DS patients to a variety of autoimmune diseases like diabetes,thyroid disorders and celiac disease is also well established suggesting impaired immune response especially cell mediated *** the last 3 decades,a few cases of Systemic Lupus Erythematosis(SLE)have been identified and reported internationally,this case report adds to this rare association and also endorses the need to carefully evaluate and investigate the DS individuals for the presence of connective tissue disorders especially if there is already an existing autoimmune disorder like diabetes,celiac or thyroid disorder.

关键词： Down’s syndrome Systemic Lupus Erythematosis Diabetes mellitus

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高山杜鹃根腐病病原学研究

高山杜鹃根腐病病原学研究

Magnetic resonance imaging characterization of circumferential and longitudinal strain under various coronary interventions in swine

中国植物病理学会2021年学术年会

作者：刘迎龙何鹏搏何鹏飞吴毅歆 Shahzad Munir suhail Asad 汤再祥张寒涛何月秋云南农业大学云南海达新生态环境建设有限公司

高山杜鹃(Rhododendron lapponicum)因其具有较高的园艺价值而被广泛种植。但随着种植时间的延长和规模扩大,一种新的根腐病引起高山杜鹃种植基地大量苗木死亡,且发病率等于死亡率。然而,其病原还不清楚。为了明确病因,笔者于2021年1月... 详细信息

高山杜鹃(Rhododendron lapponicum)因其具有较高的园艺价值而被广泛种植。但随着种植时间的延长和规模扩大,一种新的根腐病引起高山杜鹃种植基地大量苗木死亡,且发病率等于死亡率。然而,其病原还不清楚。为了明确病因,笔者于2021年1月进行了实地考察和采集样品,利用组织分离法、柯赫氏法则、形态特征观察及β-tubulin、ITS、Ypt1基因序列分析对分离物做鉴定,同时探究了病原菌的生物学特征,测定了病原物在常见园林景观植物上的寄主范围和化学药剂的室内毒力,筛选了病原拮抗微生物。根据柯赫氏法则,接种分离物Pci-1能引起高山杜鹃枯萎死亡,重新分离物仍与Pci-1形态一致,证实了该菌株为病原菌。病原菌Pci-1在pH值7.0～8.0的OA培养基及27℃的培养条件下最适宜生长,菌落白色,菌丝无隔,培养后期易形成肿胀结构和孢子囊,孢子囊呈椭圆形或卵球形,一端呈乳突状凸起或无乳突状结构,成熟后释放出大量游动孢子;基于β-tubulin、ITS、Ypt1基因序列的系统发育树均显示分离物Pci-1与樟疫霉(Phytophthora cinnamomi)聚为一枝。综合形态学与分子片段序列结果,引起高山杜鹃根腐病的病原菌Pci-1为樟疫霉。在常见的60余种园林景观植物中,Pci-1能寄生蜀葵、油菜、桃、李、栾树、杜鹃、玉兰等10多种植物离体叶片并引起腐烂。高山杜鹃根际拮抗菌多粘类芽孢杆菌P2-5和棘孢木霉NY-1对Pci-1分别有明显的抑制作用和寄生作用。对病原菌Pci-1的EC,烯酰吗啉为0.196 5μg/mL,氟吗啉为0.732 0μg/mL,烯酰·霜脲氰为0.189 4μg/mL,氟菌·霜霉威为4.692 7μg/mL和精甲·咯菌睛为1.335 5μg/mL,以烯酰吗啉毒力最高。以上研究结果表明:樟疫霉能引起高山杜鹃严重的根腐病,且寄主范围广,对云南地区的高山杜鹃和自然生态系统构成潜在威胁。本研究能为樟疫霉引起病害防控提供科学依据。

关键词：高山杜鹃疫霉根腐病樟疫霉拮抗菌烯酰吗啉

来源： cnki会议评论

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World Journal of Radiology 2013年第12期5卷 472-483页

作者： Mohammed SA suhail Mark W Wilson Steven W Hetts Maythem Saeed Department of Radiology and Biomedical Imaging School of Medicine University of California San Francisco School of Medicine University of California San Diego

AIM:To compare the acute changes in circumferential and longitudinal strain after exposing a coronary artery to various interventions in ***:Percutaneous balloon angioplasty catheter was guided to location aid device(LAD)under X-ray fluoroscopy to create different patterns of ischemic ***(n=32)were equally divided into 4 groups:controls,90 min LAD occlusion/reperfusion,LAD microembolization,and combined LAD occlusion/microembolization/*** days after interventions,cine,tagged and viability magnetic resonance imaging(MRI)were acquired to measure and compare left and right circumferential strain,longitudinal strain and myocardial viability,*** were obtained using HARP and semi-automated threshold method and statistically analyzed using unpaired *** and vascular damage was characterized ***:Coronary microemboli caused greater impairment in l left ventricular(LV)circumferential strain and dyssynchrony than LAD occlusion/reperfusion despite the significant difference in the extent of myocardial *** also caused significant decrease in peak systolic strain rate of remote myocardium and LV *** MRI demonstrated the interaction between LV and right ventricular(RV)at 3 d after *** increase in RV free wall longitudinal strain was seen in response to all *** MRI,histochemical staining and microscopy revealed different patterns of myocardial damage and microvascular ***:Cine MRI revealed subtle changes in LV strain caused by various ischemic *** also demonstrated the interaction between the right and left ventricles after coronary *** microemboli with and without acute myocardial infarction(AMI)cause complex myocardial injury and ventricular dysfunction that is not replicated in solely AMI.

关键词： Magnetic resonance imaging Percutaneous coronary interventions Acute myocardial infarct Microembolization Myocardial strain

肝肺分流:用90Y微球行放射性栓塞治疗转移性结直肠癌病人生存的一项预后指标

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国际医学放射学杂志 2017年第2期 214-215页

作者： K.H.Narsinh M.Van Buskirk A.S.Kennedy M.suhail N.Alsaikhan C.K.Hoh 解超莲 Dept of Radiology Univ of California San Diego School of Medicine

摘要目的对于不能切除而接受90Y放射栓塞治疗的肝转移性结直肠癌病人,确定其高肺分流率（LSF）能否作为其低生存率的一项独立预后指标。材料与方法本回顾性分析

关键词：转移性结直肠癌栓塞治疗预后指标肺分流放射性病人生存

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E钙黏蛋白是多种乳腺癌模型转移的决定因素

国际老年医学杂志 2020年第3期41卷 171-171页

作者：张四维(编译) 不详

癌细胞转移是导致患者死亡的主要原因之一。人们在实验中注意到癌细胞体外迁移能力与E钙黏蛋白(E-cadherin)水平呈负相关。然而大多数乳腺癌为侵袭性导管癌,并且原位肿瘤与转移灶均显著表达E-cadherin。为了解决这一差异,来自约翰霍普... 详细信息

癌细胞转移是导致患者死亡的主要原因之一。人们在实验中注意到癌细胞体外迁移能力与E钙黏蛋白(E-cadherin)水平呈负相关。然而大多数乳腺癌为侵袭性导管癌,并且原位肿瘤与转移灶均显著表达E-cadherin。为了解决这一差异,来自约翰霍普金斯大学的Padmanaban等使用小鼠和人类管腔型(luminal)和基底(basal)浸润型导管癌模型测试了E-cadherin在转移中的遗传需求。

关键词： E钙黏蛋白癌细胞转移浸润型导管癌模型测试乳腺癌模型侵袭性导管癌体外迁移转移灶

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420 nm强脉冲光治疗马拉色菌毛囊炎的临床研究

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皮肤性病诊疗学杂志 2018年第5期25卷 265-269页

作者：阿布钟泽敏胡永轩毛祖豪吴中韩雪刘康兴黄诗韵胡燕卿卢艳周冼苡南方医科大学第三附属医院皮肤性病科广东广州510630 南方医科大学广东广州510515 南方医科大学皮肤病医院广东广州510091

目的:通过IPL-420 nm照射治疗马拉色菌毛囊炎,探讨其临床疗效。方法:收集马拉色菌毛囊炎患者98例,随机分为强脉冲光治疗组(IPL组)和药物治疗组,各组均为49例。IPL组采用IPL-420 nm治疗,每周照射1～2次,连续治疗2～3周;药物治疗组采用餐... 详细信息

目的:通过IPL-420 nm照射治疗马拉色菌毛囊炎,探讨其临床疗效。方法:收集马拉色菌毛囊炎患者98例,随机分为强脉冲光治疗组(IPL组)和药物治疗组,各组均为49例。IPL组采用IPL-420 nm治疗,每周照射1～2次,连续治疗2～3周;药物治疗组采用餐后口服伊曲康唑200 mg,2次/日,连续7天。比较两组临床疗效以及复发率,并进行满意度调查。结果:治疗后1个月IPL组总有效率为95. 9%,明显高于药物治疗组的81. 6%(x^2=5. 02,P <0. 05)。治疗后3个月进行随访,IPL组复发率为6. 1%,低于药物治疗组的24. 5%(x^2=6. 38,P <0. 05)。治疗后6个月,IPL组患者满意率为93. 9%,高于药物治疗组的79. 6%(x^2=4. 35,P <0. 05)。两组患者不良反应均可耐受。结论:IPL-420 nm能够明显改善马拉色菌毛囊炎患者临床症状。

关键词：马拉色菌毛囊炎强脉冲光真菌

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