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Magnetic resonance imaging characterization of circumferential and longitudinal strain under various coronary interventions in swine

Magnetic resonance imaging characterization of circumferential and longitudinal strain under various coronary interventions in swine

作     者:Mohammed SA Suhail Mark W Wilson Steven W Hetts Maythem Saeed 

作者机构:Department of Radiology and Biomedical Imaging School of Medicine University of California San Francisco School of Medicine University of California San Diego 

出 版 物:《World Journal of Radiology》 (世界放射学杂志(英文版)(电子版))

年 卷 期:2013年第5卷第12期

页      面:472-483页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 1009[医学-特种医学] 10[医学] 

主  题:Magnetic resonance imaging Percutaneous coronary interventions Acute myocardial infarct Microembolization Myocardial strain 

摘      要:AIM:To compare the acute changes in circumferential and longitudinal strain after exposing a coronary artery to various interventions in ***:Percutaneous balloon angioplasty catheter was guided to location aid device(LAD)under X-ray fluoroscopy to create different patterns of ischemic ***(n=32)were equally divided into 4 groups:controls,90 min LAD occlusion/reperfusion,LAD microembolization,and combined LAD occlusion/microembolization/*** days after interventions,cine,tagged and viability magnetic resonance imaging(MRI)were acquired to measure and compare left and right circumferential strain,longitudinal strain and myocardial viability,*** were obtained using HARP and semi-automated threshold method and statistically analyzed using unpaired *** and vascular damage was characterized ***:Coronary microemboli caused greater impairment in l left ventricular(LV)circumferential strain and dyssynchrony than LAD occlusion/reperfusion despite the significant difference in the extent of myocardial *** also caused significant decrease in peak systolic strain rate of remote myocardium and LV *** MRI demonstrated the interaction between LV and right ventricular(RV)at 3 d after *** increase in RV free wall longitudinal strain was seen in response to all *** MRI,histochemical staining and microscopy revealed different patterns of myocardial damage and microvascular ***:Cine MRI revealed subtle changes in LV strain caused by various ischemic *** also demonstrated the interaction between the right and left ventricles after coronary *** microemboli with and without acute myocardial infarction(AMI)cause complex myocardial injury and ventricular dysfunction that is not replicated in solely AMI.

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