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Expressions of oncogenes c-fos and c-myc in skin lesion of cutaneous squamous cell carcinoma

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Asian Pacific Journal of Tropical Medicine 2014年第10期7卷 761-764页

作者： Yan Zheng Guo-Rong Wang Jin-Jing Jia su-ju luo Hao Wang Sheng-Xiang Xiao Department of Dermatology the Second Affiliated Hospital of Xi'an Jiaotong University

Objective:To explore the expressions of c-fos and c-myc in skin lesion of cutaneous squamous cell carcinoma(CSCC).Methods:Using retrospective analysis.73 cases of CSCC were selected from Department of Dermatology,the Second Affiliated Hospital of Xi'an Jiaotong *** were removed between January 2000 and January *** was considered as experimental ***.11 cases of normal skin specimens of non tumor patients were selected as control *** expression level of c-fos and c-myc was compared in the two ***:The expressions of c-fos[72.60%(53/73)]and c-myc[83.56%(61/73)]in experimental group were statistically significant(P≤0.05)compared with control group(0%).Expression of c-myc protein was negatively related to differentiation of *** difference was statistically significant(X^2=7.26.P=0.001<0.05).While expression of c-fos protein was positively related to differentiation of *** was statistically significant(X^2=7.47,P=0.0012<0.025).Conclusions:The expression level of c-fos and c-myc can be used as an importan indicator of CSCC differentiation,and it has closely connection with the differentiated degree,which can guide clinical prognosis.

关键词： Oncogene protein c-fos Oncogene protein c-myc Squamous cell carcinoma Dermatoma

Numerical modeling of all-day albedo variation for bifacial PV systems on rooftops and annual yield prediction in Beijing

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Building Simulation 2024年第6期17卷 955-964页

作者： Xiaoxiao su Chenglong luo Xinzhu Chen Jie Ji Yanshun Yu Yuandan Wu Wu Zou School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing210094China Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefei230027China Institute of Energy Research Jiangxi Academy of SciencesNanchang330096China

Bifacial PV modules capture solar radiation from both sides,enhancing power generation by utilizing reflected ***,there are difficulties in obtaining ground albedo data due to its dynamic *** address this issue,this study established an experimental testing system on a rooftop and developed a model to analyze dynamic albedo variations,utilizing specific data from the *** results showed that the all-day dynamic variations in ground albedo ranged from 0.15 to 0.22 with an average of ***,this study evaluates the annual performance of a bifacial PV system in Beijing by considering the experimental conditions,utilizing bifacial modules with a front-side efficiency of 21.23%and a bifaciality factor of 0.8,and analyzing the dynamic all-day albedo data obtained from the numerical *** results indicate that the annual radiation on the rear side of bifacial PV modules is 278.90 kWh/m^(2),which accounts for only 15.50%of the front-side ***,when using the commonly default albedo value of 0.2,the rear-side radiation is 333.01 kWh/m^(2),resulting in an overestimation of 19.40%.Under dynamic albedo conditions,the bifacial system is predicted to generate an annual power output of 412.55 kWh/m^(2),representing a significant increase of approximately 12.37%compared to an idealized monofacial PV system with equivalent front-side *** a 25-year lifespan,the bifacial PV system is estimated to reduce carbon emissions by 8393.91 kgCO_(2)/m^(2),providing an additional reduction of 924.31 kgCO_(2)/m^(2)compared to the idealized monofacial PV *** findings offer valuable insights to promote the application of bifacial PV modules.

关键词： bifacial PV module ground albedo simulation carbon emission reduction

Endoloop ligation after endoscopic mucosal resection using a transparent cap: A novel method to treat small rectal carcinoid tumors

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World Journal of Gastroenterology 2019年第10期25卷 1259-1265页

作者： Ding-Guo Zhang su luo Feng Xiong Zheng-Lei Xu Ying-Xue Li Jun Yao Li-Sheng Wang Department of Gastroenterology Shenzhen People’s HospitalFirst Affiliated Hospital of Southern University of Science and TechnologySecond Clinical Medical College of Jinan University

BACKGROUND Local endoscopic resection is an effective method for the treatment of small rectal carcinoid tumors, but remnant tumor at the margin after resection remains to be an *** To evaluate the efficacy and safety of resection of small rectal carcinoid tumors by endoloop ligation after cap-endoscopic mucosal resection(LC-EMR) using a transparent *** Thirty-four patients with rectal carcinoid tumors of less than 10 mm in diameter were treated by LC-EMR(n = 22) or endoscopic submucosal dissection(ESD)(n =12) between January 2016 and December 2017. Demographic data, complete resection rates, pathologically complete resection rates, operation duration, and postoperative complications were collected. All cases were followed for 6 to 30 *** A total of 22 LC-EMR cases and 12 ESD cases were enrolled. The average age was48.18 ± 12.31 and 46.17 ± 12.57 years old, and the tumor size was 7.23 ± 1.63 mm and 7.50 ± 1.38 mm, respectively, for the LC-EMR and ESD groups. Resection time in the ESD group was longer than that in the LC-EMR group(15.67 ± 2.15 min vs 5.91 ± 0.87 min; P surgery(TEM) and tumor cells were not identified in the postoperative specimens. The other case with a positive margin chose follow-up without further operation. One case with remnant tumor after ESD received further local ligation treatment. Neither local recurrence nor lymph node metastasis was found during the follow-up *** LC-EMR appears to be an efficient and simple method for the treatment of small rectal carcinoid tumors, which can effectively avoid margin remnant tumors.

关键词： Rectal carcinoid Endoscopic submucosal dissection Endoscopic mucosal resection Ligation

Pseudomonas aeruginosa regulator PvrA binds simultaneously to multiple pseudo-palindromic sites for efficient transcription activation

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Science China(Life Sciences) 2024年第5期67卷 900-912页

作者： Yibo Zhu Bingnan luo Xingyu Mou Yingjie Song Yonghong Zhou Yongbo luo Bo sun Youfu luo Hong Tang Zhaoming su Rui Bao Center of Infectious Diseases Division of Infectious Diseases in State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China Department of Geriatrics and National Clinical Research Center for Geriatrics West China HospitalSichuan UniversityChengdu 610041China Key Laboratory of Biodiversity and Environment on the Qinghai-Tibetan Plateau Ministry of EducationSchool of Ecology and EnvironmentTibet UniversityLhasa 850000China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China College of Life Science Sichuan Normal UniversityChengdu 610101China Accurate Biotechnology(Hunan)Co. LtdChangsha 410006China

Tetracycline repressor(TetR)family regulators(TFRs)are the largest group of DNA-binding transcription factors and are widely distributed in bacteria and *** play vital roles in controlling the expression of various genes and regulating diverse physiological ***,a TFR protein Pseudomonas virulence regulator A(PvrA),was identified from Pseudomonas aeruginosa as the transcriptional activator of genes involved in fatty acid utilization and bacterial ***,we show that PvrA can simultaneously bind to multiple pseudo-palindromic sites and upregulate the expression levels of target ***-electron microscopy(cryo-EM)analysis indicates the simultaneous DNA recognition mechanism of PvrA and suggests that the bound DNA fragments consist of a distorted B-DNA double *** crystal structure and functional analysis of PvrA reveal a hinge region that secures the correct domain motion for recognition of the promiscuous ***,our results showed that mutations disrupting the regulatory hinge region have differential effects on biofilm formation and pyocyanin biosynthesis,resulting in attenuated bacterial ***,these findings will improve the understanding of the relationship between the structure and function of the TetR family and provide new insights into the mechanism of regulation of *** virulence.

关键词： Pseudomonas aeruginosa transcription regulator TetR protein-structure virulence

探讨经腹部超声引导宫腔管置入在不同分期宫颈癌患者三维腔内近距离放射治疗中的应用价值分析

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影像研究与医学应用 2024年第10期8卷 37-39,43页

作者：李云鲁亮李勇罗素陈玲刘麒麟韦泫妤贵州省人民医院肿瘤科贵州贵阳550000 贵州省人民医院超声科贵州贵阳550000

目的:探讨经腹部超声(TAUS)引导宫腔管置入在ⅠB1~ⅣB期宫颈癌患者三维腔内近距离放射治疗(3D-ICB)中的临床应用及价值。方法:选取2023年6月—12月在贵州省人民医院收治的48例宫颈癌患者为研究对象,按宫腔管置入方法分为常规置入组(24例... 详细信息

目的:探讨经腹部超声(TAUS)引导宫腔管置入在ⅠB1~ⅣB期宫颈癌患者三维腔内近距离放射治疗(3D-ICB)中的临床应用及价值。方法:选取2023年6月—12月在贵州省人民医院收治的48例宫颈癌患者为研究对象,按宫腔管置入方法分为常规置入组(24例)和TAUS组(24例),每组均进行120次近距离放射治疗,经CT定位扫描验证两组患者的子宫隐匿穿孔率。结果:TAUS组与常规置入组比较,操作时长缩短(18.71 min vs 13.09 min,P=0.001),术中出血比例下降(19.16%vs 15.83%,P=0.611),CT扫描次数减少(121次vs 132次),隐匿性穿孔率下降(0.83%vs 5.83%,P=0.031),其中TAUS组与常规置入组各个分期穿孔率比较:ⅠB1~ⅡA2期(0.00%vs 0.00%);ⅡB~ⅢB期(0.00%vs 2.20%,P=0.343);ⅢC~ⅣB期(1.54%vs 10.00%,P=0.040)。结论:TAUS引导可以减少不同分期宫颈癌患者在3D-ICB宫腔管置入术中的时长,同时降低ⅢC~ⅣB期宫颈癌患者术后隐匿性穿孔率,为宫颈癌患者尤其是晚期患者的3D-ICB提供了一个更加安全有效的方法。

关键词：宫颈癌三维腔内近距离放射治疗经腹超声引导子宫穿孔

Application of efficient and sustainable freeze-dissolving technology in manufacturing of KHCO_(3)ultrafine particles

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Green Chemical Engineering 2024年第2期5卷 266-272页

作者： Jiaqi luo Qifan su Qiushuo Yu Xinyue Zhai Yuan Zou Huaiyu Yang School of Chemical Engineering Chemical Engineering Research Center of the Ministry of Education for Advanced Use Technology of Shanbei EnergyInternational Science&Technology Cooperation Base of MOST for Clean Utilization of Hydrocarbon ResourcesNorthwest UniversityXi’an710069China Department of Chemical Engineering Loughborough UniversityLoughboroughLE113TUUnited Kingdom

The development of ultrafine particles provided a new way to solve problems in the fields of energy,environment,and medicine,and had become one of the most promising ***,the application of ultrafine particles required the development of cleaner,greener,and more efficient preparation *** new freeze-dissolving technology has been applied in manufacturing of KHCO_(3)ultrafine particles,with an aqueous solution of 0.02-0.1 g KHCO_(3)/g *** ice particles were formed after dripping the solution into liquid *** antisolvent ethanol was used to dissolve the ice spherical template at a temperature below 273.15 K,and the pre-formed KHCO_(3)ultrafine particles inside the ice template remained in the ethanol aqueous *** ice particles were put into the freeze dryer to isolate the ultrafine KHCO_(3)*** with the particles produced with traditional freeze-drying technology,the ultrafine powder/particles produced by the freeze-dissolving technology were smaller with narrower size *** freeze-dissolving technology has demonstrated a much more sustainable and efficient manufacturing process than the traditional freeze-drying *** addition,the influence of the concentrations of KHCO_(3)and the sizes of ice particles were investigated with the discussions of mechanisms.

关键词： Freeze-dissolving Freeze-drying Ultrafine particles sustainable

Neurolymphomatosis caused by diffuse large B-cell lymphoma presenting as isolated brachial plexopathy

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Chinese Medical Journal 2019年第22期132卷 2762-2764页

作者： Heng Li su-Shan luo Chong-Bo Zhao Department of Neurology Jinan Central HospitalShandong UniversityJinanShandong 250013China Department of Neurology Huashan HospitalFudan UniversityShanghai 200040China

To the Editor:A 66-year-old female complained of muscle weakness,numbness,and pain in her left shoulder and arm for 16 months,after which muscle atrophy and forearm swelling gradually *** admission,she had been diagnosed with brachial plexus neuritis and received intravenous methylprednisolone with 500 mg for 3 days,followed by a tapering of oral ***,she did not benefit much from the *** personal medical history and family history were not *** previous chest computed tomography(CT)scan and magnetic resonance imaging(MRI)scans of her brain,cervical spinal cord,and brachial plexus[Figure 1A]were not remarkable.

关键词： brachial lymphoma atrophy

Osteology of Leptobrachella bijie(Anura,Megophryidae)

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Asian Herpetological Research 2024年第2期15卷 90-103页

作者： Wei LI Meihua ZHANG Zhonghao luo Jing LIU Tuo SHEN Bo CHEN Haijun su Bin WANG College of Forestry Guizhou UniversityGuiyang 550025GuizhouChina Chengdu Institute of Biology Chinese Academy of SciencesChengdu 610041SichuanChina

The Asian leaf litter toad genus Leptobrachella contains more than 100 species widely distributed in southwestern ***,the systematic profiles of this group remain *** morphology is important for taxonomic and phylogenetic ***,few studies have focused on the osteology of the ***,we comprehensively described the osteological features of a representative species *** based on micro-CT scanning and double-staining *** results show that the skull of adult *** is well-ossified,exhibiting sexual dimorphism and minimal intraspecific *** skull length is slightly greater than the width,with the maxilla slightly overlapping with the *** nasal connects with the sphenethmoid in males,but only part or not connects with the sphenethmoid in *** transverse processes of the sacrum are robust and symmetrically butterfly-shaped,and the presacral vertebrae are *** pectoral girdle is *** phalangeal formula is 2-2-3-3 for the hand,and 2-2-3-4-3 for the *** study provides the first detailed and comprehensive osteological accounts of the genus Leptobrachella.

关键词： sexual dimorphism skeleton taxonomy

Impact of propofol and sevoflurane anesthesia on cognition and emotion in gastric cancer patients undergoing radical resection

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World Journal of Gastrointestinal Oncology 2024年第1期16卷 79-89页

作者： Ao-Han Li su Bu Ling Wang Ai-Min Liang Hui-Yu luo Department of Anesthesiology Xiangyang No.1 People's HospitalHubei University of MedicineXiangyang 441000Hubei ProvinceChina Department of Cardiothoracic surgery Xiangyang No.1 People's HospitalHubei University of MedicineXiangyang 441000Hubei ProvinceChina Department of Rehabilitation Xiangyang No.1 People's HospitalHubei University of MedicineXiangyang 441000Hubei ProvinceChina Department of Internal Medicine-Cardiovascular Xiangyang No.1 People's HospitalHubei University of MedicineXiangyang 441000Hubei ProvinceChina

BACKGROUND Propofol and sevoflurane are commonly used anesthetic agents for maintenance anesthesia during radical resection of gastric ***,there is a debate concerning their differential effects on cognitive function,anxiety,and depression in patients undergoing this *** To compare the effects of propofol and sevoflurane anesthesia on postoperative cognitive function,anxiety,depression,and organ function in patients undergoing radical resection of gastric *** A total of 80 patients were involved in this *** subjects were divided into two groups:Propofol group and sevoflurane *** evaluation scale for cognitive function was the Loewenstein occupational therapy cognitive assessment(LOTCA),and anxiety and depression were assessed with the aid of the self-rating anxiety scale(SAS)and self-rating depression scale(SDS).Hemodynamic indicators,oxidative stress levels,and pulmonary function were also *** The LOTCA score at 1 d after surgery was significantly lower in the propofol group than in the sevoflurane ***,the SAS and SDS scores of the sevoflurane group were significantly lower than those of the propofol *** sevoflurane group showed greater stability in heart rate as well as the mean arterial pressure compared to the propofol ***,the sevoflurane group displayed better pulmonary function and less lung injury than the propofol *** Both propofol and sevoflurane could be utilized as maintenance anesthesia during radical resection of gastric *** anesthesia has a minimal effect on patients'pulmonary function,consequently enhancing their postoperative *** anesthesia causes less impairment on patients'cognitive function and mitigates negative emotions,leading to an improved postoperative mental ***,the selection of anesthetic agents should be based on the individual patient's specific circumstances.

关键词： Propofol Sevoflurane Radical resection of gastric cancer Anesthetic effect Cognitive function Negative emotion