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Good and bad dispositions between archaea and bacteria in the human gut:New insights from metagenomic survey and co-occurrence analysis

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Synthetic and Systems Biotechnology 2024年第1期9卷 88-98页

作者： Francesco Candeliere Laura Sola stefano raimondi Maddalena Rossi Alberto Amaretti Department of Life Sciences University of Modena and Reggio Emilia41125 ModenaItaly Biogest-Siteia University of Modena and Reggio Emilia41125 ModenaItaly

Archaea are an understudied component of the human *** this study,the gut archaeome and bacteriome of 60 healthy adults from different region were analyzed by whole-genome shotgun *** were ubiquitously found in a wide range of abundances,reaching up to 7.2%.The dominant archaeal phylum was Methanobacteriota,specifically the family Methanobacteriaceae,encompassing more than 50%of Archaea in 50 *** previously underestimated Thermoplasmatota,mostly composed of Methanomassiliicoccaceae,dominated in 10 subjects(>50%)and was present in all others except ***,the sole other archaeal phylum,occurred in negligible concentration,except for two samples(4.6-4.8%).This finding confirmed that the human gut archaeome is primarily composed of methanogenic organisms and among the known methanogenic pathway:i)hydrogenotrophic reduction of CO_(2) is the predominant,being the genus Methanobrevibacter and the species Methanobrevibacter smithii the most abundant in the majority of the samples;ii)the second pathway,that involved Methanomassiliicoccales,was the hydrogenotrophic reduction of methyl-compounds;iii)dismutation of acetate or methyl-compounds seemed to be ***-occurrence analysis allowed to unravel correlations between Archaea and Bacteria that shapes the overall structure of the microbial community,allowing to depict a clearer picture of the human gut archaeome.

关键词： Gut microbiota Archaea Metagenome Co-occurrence Methanomassiliicoccus Methanobrevibacter smithii

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Comparison of 2D and 4D Flow MRI Measurements for Hemodynamic Evaluation of the Fontan Palliation

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Congenital Heart Disease 2023年第6期18卷 627-638页

作者： Elisa Listo Nicola Martini stefano Salvadori Elisa Valenti Nicola Stagnaro Gianluca Trocchio Chiara Marrone Alberto Clemente Francesca raimondi Pierluigi Festa Lamia Ait Ali Department of Radiology IRCCS Istituto Giannina GasliniGenovaItaly U.O.C.Bioingegneria Gabriele Monasterio CNR-Tuscany FoundationPisaItaly Institute of Clinical Physiology CNR PisaItaly Cardiology Unit IRCCS Istituto Giannina GasliniGenovaItaly Pediatric Cardiology and GUCH Unit Massa Gabriele Monasterio CNR-Tuscany FoundationMassaItaly Gabriele Monasterio CNR-Tuscany Foundation PisaItaly Department of Cardiology Azienda Ospedaliero-Universitaria MeyerFlorenceItaly Institute of Clinical Physiology CNR MassaItaly

Background:The assessment of Fontan circuit’sﬂow is traditionally evaluated by multiple through-plane phase-contrast MRI acquisitions(2Dﬂow),while recently,a single volumetric 4D-ﬂow MRI acquisition is emerging as a comprehensive tool for the hemodynamic evaluation in congenital heart ***:To compare 2D and 4D-ﬂow MRI measurements in patients after Fontan palliation and to evaluate parameters affecting potential ***:39 patients after Fontan palliation(23 males,age 22±11 years)who underwent cardiac MRI with 2D and 4D-ﬂow MRI acquisition were included in the *** all patients,bloodﬂow quantiﬁcation in the Fontan circuit and aorta by 2Dﬂow and by 4Dﬂow MRI acquisition blinding to the 2D results was *** agreement between 2D and 4D-ﬂow MRI was calculated as the intraclass correlation coefﬁcient(ICC).The mean absolute differences between 4D and 2Dﬂows were analyzed using linear regression ***:4D-ﬂow MRI acquisition time was slightly lower than 2D(7.6±1.8 min vs.9.4±3.3 min,p=0.03).Flow was slightly predominant in the right pulmonary artery(58%of total pulmonaryﬂow).Conduit/tunnel-pul-monary arteriesﬂow accounted for 60%of the Fontan *** between 2D and 4D was overall good-to-excellent from ICC:0.81795%CI:0.637–0.907 to 0.93295%CI:0.866–*** was no signiﬁcant inﬂu-ence of evaluated parameters on the agreement on 4D and 2Dﬂ***:4D-ﬂow MRI represents a valid tool in Fontan’sﬂow quantiﬁ*** larger studies are needed to conﬁrm our results and to evaluate the impact of advanced 4D-ﬂow MRI parameters on the prognostic stratiﬁcation in patients after Fontan palliation.

关键词： Fontan palliation fontanﬂows 4Dﬂow MRI 2Dﬂow MRI cardiac magnetic resonance

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符码的游戏艺术

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现代装饰 2019年第9期 100-107页

作者： stefano Giovannoni Qeeboo Marcantonio raimondi Malerba David Trubridge Offecct OKHA Showroom MARTINELLI VENEZIA Umbrella Jordi LLopis Jaime Hayon Bdbarcelona Elena Salmistraro Bethan Laura Wood Extra & Ordinary 苏烨 A Design Studio

'人民日报开淘宝店',于我而言,是八月份最大的趣闻。无论是品牌通过跨界合作重温青春,亦或者是媒介延展下的符号升华,都意味着严肃符码转型之旅已经开启。罗兰·巴特认为,媒介营造时空包围圈,语言符号、视觉符号和听觉符号在其中相互转... 详细信息

'人民日报开淘宝店',于我而言,是八月份最大的趣闻。无论是品牌通过跨界合作重温青春,亦或者是媒介延展下的符号升华,都意味着严肃符码转型之旅已经开启。罗兰·巴特认为,媒介营造时空包围圈,语言符号、视觉符号和听觉符号在其中相互转换,调动联想,与大众一起演绎合理想象的神话。这暗含了符号内涵的层次艺术,意味深远。而若同以'泛媒介'视角窥探设计界,也有惊喜发现:

关键词：游戏艺术长颈鹿 ECA

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