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World Journal of Gastroenterology 2011年第5期17卷 677-680页

作者： Giovanni D De Palma stefania Staibano Saverio Siciliano Francesco Maione Maria Siano Dario Esposito Giovanni Persico Department of Surgery and Advanced Technologies Center of Excellence for Technical Innovation in SurgerySection of Diagnostic and Therapeutic EndoscopyUniversity of Naples Federico IISchool of Medicine80131NaplesItaly Department of Biomorphological and Functional Sciences Section of PathologyUniversity of Naples Federico IISchool of Medicine80131NaplesItaly

Recently,the use of confocal laser endomicroscopy(CLE) in the diagnosis of chronic ulcerative colitis(CUC) was *** this brief report we aimed to assess the application of probe-based CLE to characterize colonic mucosa and dysplasia in *** study involved a patient presenting long-standing *** imaging of both the inflamed mucosa,a circumscribed lesion(dysplasiaassociated lesional mass),and adjacent colonic mucosa are demonstrated and the correlation between the CLE and histological *** mucosa and dysplasia showed specific alteration of crypt architecture,cellular infiltration,and vessel architecture with an excellent correlation between CLE and standard histological examination.

关键词：溃疡性结肠炎共聚焦高清晰度激光探头表征体内结构改变

Mechanisms of altered bone remodeling in children with type 1 diabetes

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World Journal of Diabetes 2021年第7期12卷 997-1009页

作者： Giacomina Brunetti Gabriele D'Amato stefania De Santis Maria Grano Maria Felicia Faienza Department of Biosciences Biotechnologies and BiopharmaceuticsUniversity"A.Moro"of BariBari 70125Italy Department of Women’s and Children’s Health ASL BariNeonatal Intensive Care UnitDi Venere HospitalBari 70124Italy Department of Pharmacy-Drug Science University of Bari Aldo MoroBari 70126Italy Department of Emergency and Organ Transplantation Univ BariBari 70124Italy Department of Biomedical Sciences and Human Oncology Pediatric UnitUniversity"A.Moro"Bari 70124Italy

Bone loss associated with type 1 diabetes mellitus(T1DM)begins at the onset of the disease,already in childhood,determining a lower bone mass peak and hence a greater risk of osteoporosis and fractures later in *** mechanisms underlying diabetic bone fragility are not yet completely *** and insulin deficiency can affect the bone cells functions,as well as the bone marrow fat,thus impairing the bone strength,geometry,and *** factors,like insulin and growth hormone/insulin-like growth factor 1,can control bone marrow mesenchymal stem cell commitment,and the receptor activator of nuclear factor-κB ligand/osteoprotegerin and Wnt-b catenin pathways can impair bone *** myokines may have a key role in regulating metabolic control and improving bone mass in T1DM *** aim of this review is to provide an overview of the current knowledge of the mechanisms underlying altered bone remodeling in children affected by T1DM.

关键词： Type 1 diabetes Children Bone remodeling Osteoclasts Osteoblasts

Increased phosphorus availability to corn resulting from the simultaneous applications of phosphate rock, calcareous rock, and biochar to an acid sandy soil

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Pedosphere 2020年第6期30卷 719-733页

作者： Rogério Borguete Alves RAFAEL Maria Luisa FERNÁNDEZ-MARCOS stefania COCCO Maria Letizia RUELLO Flavio FORNASIER Giuseppe CORTI Department of Rural Engineering Faculty of Agronomy and Forestry EngineeringUniversidade Eduardo MondlaneMaputo 257Mozambique Department of Agriculture Food and Environmental SciencesUniversitàPolitecnica delle MarcheAncona 60131Italy Department of Soil Science and Agricultural Chemistry Universidad de Santiago de CompostelaLugo 27002Spain Department of Materials Environmental Sciences and Urban PlanningUniversitàPolitecnica delle MarcheAncona 60131Italy Consiglio per la Ricerca e la Sperimentazione in Agricoltura Centro di Ricerca per lo Studio delle Relazioni tra Pianta e Suolo(C.R.E.A.-R.P.S.)Gorizia 34170Italy Instituto de Biodiversidade Agraria e Desenvolvemento Rural Universidad de Santiago de CompostelaLugo 27002Spain

Phosphorus(P)deficiency is one of the main constraints on crop production in Arenosols(acid sandy soil).The high cost of P fertilizers may represent an insurmountable obstacle in many poor countries,leaving the exploitation of their own calcareous and phosphate rocks as the only low-cost and long-term *** is suggested to have positive effects on soil properties;however,there is no published research on the synergistic effects of biochar and rocky materials in modifying soil *** aim of this study was to investigate the chemical and biochemical responses of an acid Arenosol treated with phosphate rock(PR),calcareous rock(CR),and biochar(BC),and the implications for corn yield.A soil from Marracuene District,Mozambique was used,where corn was grown for 90 d with the soil treated with:no addition(control),water-soluble zinc phosphite fertilizer(WSP),PR,WSP+CR,WSP+BC,WSP+CR+BC,PR+BC,and PR+CR+*** was produced by pyrolysis of babycorn peels for 4 h at 450?C and applied at 11 g *** soil pHH2 Oincreased from about 4.54 in the control to 7.38 in the PR+CR+BC *** oxidizable organic carbon,cation exchange capacity,and available P were higher in the treatments containing BC than in the *** treatments containing CR and/or BC led to the highest activities of alkaline phosphomonoesterase,phosphodiesterase,andα-glucosidase,which increased P availability and gave the greatest biomass and *** suggest that biochar provides additional soluble P and supplies adsorption sites for phosphate,preventing its evolution to unavailable ***,PR applied together with BC contributed to an 840%yield increase compared to the *** treatments containing WSP and BC facilitated phosphite oxidation to phosphate and increased crop yield.

关键词： Arenosols available P enzyme activity phosphite oxidation soil fertility

Label-free sensing of ultralow-weight molecules with all-dielectric metasurfaces supporting bound states in the continuum

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Photonics Research 2018年第7期6卷 726-733页

作者： SILVIA ROMANO GIANLUIGI ZITO stefania TORINO GIUSEPPE CALAFIORE ERIKA PENZO GIUSEPPE COPPOLA STEFANO CABRINI IVO RENDINA VITO MOCELLA Institute for Microelectronics and Microsystems Unit of Naples National Council of Research Institute of Protein Biochemistry National Council of Research Lawrence Berkeley National Laboratory Molecular Foundry Division

The realization of an efficient optical sensor based on a photonic crystal metasurface supporting bound states in the continuum is reported. Liquids with different refractive indices, ranging from 1.4000 to 1.4480, are infiltrated in a microfluidic chamber bonded to the sensing dielectric metasurface. A bulk liquid sensitivity of 178 nm/RIU is achieved, while a Q-factor of about 2000 gives a sensor figure of merit up to 445 in air at both visible and infrared excitations. Furthermore, the detection of ultralow-molecular-weight(186 Da) molecules is demonstrated with a record resonance shift of 6 nm per less than a 1 nm thick single molecular layer. The system exploits a normal-to-the-surface optical launching scheme, with excellent interrogation stability and demonstrates alignment-free performances, overcoming the limits of standard photonic crystals and plasmonic resonant configurations.

关键词：高效光学传感器折射率理论研究通讯技术

Flexible mating tactics and associated reproductive effort during the rutting season in male reindeer （Rangifer tarandus, L. 1758）

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Current Zoology 2015年第5期61卷 802-810页

作者： Eliana PINTUS stefania UCCHEDDU Knut H. RФED Javier Perez GONZALEZ Juan CARRANZA Mauri NIEMINEN Фystein HOLAND Department of Veterinary Sciences Faculty of Agrobiology Food and Natural Resources Czech University of Life Sciences Kamycka 129 165 21 Prague 6 - Suchdol Czech Republic Ungulate Research Unit Game and Fish Research Center University of Cordoba 14071 Cordoba Spain Department of Basic Sciences and Aquatic Medicine Norwegian University of Life Sciences EO. Box 8146 Dep. N-0033 Oslo Norway Guarderia Rural Mancomunidad de Municipios Centro (MIMC) 06810 Calamonte Spain Finnish Game and Fisheries Research Institute Reindeer Research Station 99910 Kaamanen Finland Department of Animal and Aquacultural Sciences Norwegian University of Life Sciences RO. Box 5003 N-1432 As Norway

Polygynous males can change their mating tactics across their lifetime, but information is scarce on the flexibility of this trait within a given season and the relative costs and benefits of using different tactics. Here, we monitored individually marked male reindeerRangifer tarandusand classified their mating tactics as harem-defense, sneaking, or mixed. The costs of the male reproductive effort were assessed using both direct (i.e. percentage of body mass lost) and indirect measures (i.e. activity patterns such as feeding, standing, and walking), while mating group size and reproductive success were recorded as mating effort benefits. Our results show that reindeer males may switch between the harem-defense and sneaking tactics throughout the same breeding season, providing further support to the notion that reproductive tactics are flexible in ungulates. The costs and benefits of male mating effort vary according to the mating tactic, reaching the highest values in harem-holders and the lowest values in sneaking males. Moreover, males who switched between the sneaking tactic and the harem-defence tactic tended to achieve higher mating success than males who consistently used the least costly tactic. Indeed, all harem-holders successfully sired offspring, whereas only two out of three mixed-tactic males sired one calf, and sneaking males did not sire any calves. In conclusion, our results show that reindeer males can modulate their mating efforts during the same breeding season by switching between the most costly harem-defense tactic and the least costly sneaking tactic, suggesting individual solutions to the balance between reproductive effort and mating opportunities.

关键词：繁殖成功率交配策略繁殖季节驯鹿雄性男性生殖成本效益混合策略

汉传佛教多元化图景中边缘女性的经验——近现代四川比丘尼的隐形和显形

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西南民族大学学报（人文社会科学版） 2022年第3期43卷 50-56页

作者： [意]史芬妮肖习(译) 伦敦大学亚非学院西南民族大学哲学学院四川成都610041

佛教的历史往往被描述为一个个僧侣的历史,大众特别关注那些被挑选出来的"杰出"人物。笔者建议采取另一种方法,即关注本地的微型社区,把小型尼众道场带入研中心,倾听那些比丘尼闻所未闻的声音。基于档案研究和在四川进行的广泛田野调查... 详细信息

佛教的历史往往被描述为一个个僧侣的历史,大众特别关注那些被挑选出来的"杰出"人物。笔者建议采取另一种方法,即关注本地的微型社区,把小型尼众道场带入研中心,倾听那些比丘尼闻所未闻的声音。基于档案研究和在四川进行的广泛田野调查,本文将呈现一部另类历史:"不知名"的比丘尼成为主角,边缘成为典范,并依次重新定义"卓越"(eminence)这一概念。本文所研究的尼众道场位于大成都范围内,主要分布在近现代名为郫县、温江县、华阳县、成都县,和成都之外的遂宁、内江区域。

关键词：四川佛教成都佛教遂宁佛教内江佛教比丘尼僧伽教育

In Vivo Toxicity Assessment of Gold Nanoparticles in Drosophila melanogaster

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Nano Research 2011年第4期4卷 405-413页

作者： Pier Paolo Pompa Giuseppe Vecchio Antonio Galeone Virgilio Brunetti stefania Sabella Gabriele Maiorano Andrea Falqui GiovanniBertoni Roberto Cingolani Italian Institute of Technology Center for Bio-Molecular Nanotechnology Via Barsanti 1-73010 Arnesano （Lecce） Italy Italian Institute of Technology Central Research Laboratories Via Morego 30-16136 Genova Italy

在商业商品和新奇技术的 nanomaterials 的成长使用正在产生为人的健康和环境关于可能的风险增加问题，由于对他们的潜在的毒性的一个深入的评价的缺乏。在这上下文，我们在摄取之上在模型系统果蝇 melanogaster 上调查了盖住柠檬酸盐的... 详细信息

在商业商品和新奇技术的 nanomaterials 的成长使用正在产生为人的健康和环境关于可能的风险增加问题，由于对他们的潜在的毒性的一个深入的评价的缺乏。在这上下文，我们在摄取之上在模型系统果蝇 melanogaster 上调查了盖住柠檬酸盐的金 nanoparticles (AuNPs ) 的效果。我们观察了一在 vivo 毒性重要 AuNPs，在对待的有机体得到了清楚的不利效果，。传播电子显微镜学在果蝇的纸巾表明了 nanoparticles 的本地化。在 nanoscale 材料的 vivo 毒性的高度的试验性的证据，它是广泛地考虑了在它的体积表格是保险箱和 biocompatible，在许多领域，包括的 nanomedicine，材料科学，健康，药交货和风险里开创重要问题评价。

关键词：金纳米粒子毒性评估果蝇体内透射电子显微镜人类健康纳米材料 DNA片段

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一座因移民而兴旺的岛屿

商业周刊（中文版） 2023年第23期 36-38页

作者： stefania D'Ignoti 程玺(译) 不详

兰佩杜萨岛已成为难民的代名词,当地人希望游客了解难民的困境在兰佩杜萨的烈日下,离游客上下船港口不远的一处悬崖上,嘉立着高5米、宽3米的“欧洲之门”这是意大利雕塑家米莫·帕拉迪诺(Mimmo Paladino)2008年的作品,面向突尼斯方向,... 详细信息

兰佩杜萨岛已成为难民的代名词,当地人希望游客了解难民的困境在兰佩杜萨的烈日下,离游客上下船港口不远的一处悬崖上,嘉立着高5米、宽3米的“欧洲之门”这是意大利雕塑家米莫·帕拉迪诺(Mimmo Paladino)2008年的作品,面向突尼斯方向,原本是一件临时装置作品。但由于这座意大利小岛在几年后成为难民抵达的前线,当地政府决定让它成为永久装置,以提醒人们有成千上万人葬身于前往欧洲的大海上。

关键词：装置作品难民突尼斯雕塑家意大利当地政府游客

Role of Arabidopsis UV RESISTANCE LOCUS 8 in Plant Growth Reduction under Osmotic Stress and Low Levels of UV-B

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Molecular Plant 2014年第5期7卷 773-791页

作者： Rossella Fasano Nathalie Gonzalez Alessandra Tosco Fabrizio Dal Piaz Teresa Docimo Ramon Serrano stefania Grillo Antonella Leone Dirk Inze Department of Pharmacy University of Salerno Fisciano Italy Department of Plant Systems Biology VIB 9052 Ghent Belgium Department of Plant Biotechnology and Bioinformatics Ghent University 9052 Gent Belgium Max Planck Institute for Chemical Ecology Jena Germany Instituto de Biologia Molecular y Celular de Plantas Universidad Politecnica de Valencia CSIC Valencia Spain National Research Council of Italy Institute of Plant Genetics Res. Div. Portici Portici Italy

In high-light environments, plants are exposed to different types of stresses, such as an excess of UV-B, but also drought stress which triggers a common morphogenic adaptive response resulting in a general reduction of plant growth. Here, we report that the Arabidopsis thaliana UVRESISTANCE LOCUS 8 （UVR8） gene, a known regulator of the UV-B morphogenic response, was able to complement a Saccharomyces cerevisiae osmo-sensitive mutant and its expression was induced after osmotic or salt stress in Arabidopsis plants. Under low levels of UV-B, plants overexpressing UVR8 are dwarfed with a reduced root development and accumulate more flavonoids compared to control plants. The growth defects are mainly due to the inhibition of cell expansion. The growth inhibition triggered by UVR8 overexpression in plants under low levels of UV-B was exacerbated by mannitol-induced osmotic stress, but it was not significantly affected by ionic stress. In contrast, uvr8-6 mutant plants do not differ from wild-type plants under standard conditions, but they show an increased shoot growth under high-salt stress. Our data suggest that UVR8-mediated accumulation of flavonoid and possibly changes in auxin homeostasis are the underlying mechanism of the observed growth phenotypes and that UVR8 might have an important role for integrating plant growth and stress signals.

关键词： osmotic stress growth reduction cell expansion flavonoid auxin.

Narrow-band imaging endoscopy to assess mucosal angiogenesis in inflammatory bowel disease: A pilot study

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World Journal of Gastroenterology 2010年第19期16卷 2396-2400页

作者： Silvio Danese Gionata Fiorino Erika Angelucci stefania Vetrano Nico Pagano Giacomo Rando Antonino Spinelli Alberto Malesci Alessandro Repici Division of Gastroenterology IRCCS Istituto Clinico Humanitas Rozzano Milan 20089 Italy Department of Surgery IRCCS Istituto Clinico Humanitas Rozzano Milan 20089 Italy Department of Translational Medicine Univer-sity of Milan Milan 20100 Italy

AIM: To investigate whether narrow band imaging (NBI) is a useful tool for the in vivo detection of angiogenesis in inflammatory bowel disease (IBD) patients. METHODS: Conventional and NBI colonoscopy was performed in 14 patients with colonic inflammation (8 ulcerative colitis and 6 Crohn’s disease). Biopsy samples were taken and CD31 expression was assayed immuno- histochemically; microvascular density was assessed by vessel count. RESULTS: In areas that were endoscopically normal but positive on NBI, there was a significant (P < 0.05) increase in angiogenesis (12 ± 1 vessels/field vs 18 ± 2 vessels/field) compared with areas negative on NBI. In addition, in areas that were inflamed on white light endoscopy and positive on NBI, there was a significant (P < 0.01) increase in vessel density (24 ± 7 vessels/f ield) compared with NBI-negative ***: NBI may allow in vivo imaging of intestinal angiogenesis in IBD patients.

关键词： Narrow-band imaging Angiogenesis Inflammatory bowel disease Crohn’s disease Ulcerative colitis