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Prediction of cognitive scores by joint use of movie-watching fMRI connectivity and eye tracking via Attention-CensNet

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Psychoradiology 2023年第1期3卷 193-202页

作者： Jiaxing Gao Lin Zhao Tianyang Zhong Changhe Li Zhibin He Yaonei Wei Shu Zhang Lei Guo Tianming Liu Junwei Han xi Jiang Tuo Zhang School of Automation Northwestern Polytechnical UniversityXIi'an 710072China Cortical Architecture Imaging and Discovery laboratory Department of Computer Science and Bioimaging Research CenterThe University of GeorgiaAthensGA 30602USA School of Computer Science Northwestern Polytechnical UniversityXi'an 710072China School of Life Science and Technology MOE Key Laboratory for NeuroinformationUniversity of Electronic Science and Technology of ChinaChengdu 611731China

Background:Brain functional connectivity under the naturalistic paradigm has been shown to be better at predicting individual behaviors than other brain states,such as rest and doing ***,the state-of-the-art methods have found it difcult to achieve desirable results from movie watching paradigm functional magnetic resonance imaging(mfMRI)-induced brain functional connectivity,especially when there are fewer *** other physical measurements into the prediction method may enhance *** tracking,becoming popular due to its portability and lower expense,can provide abundant behavioral features related to the output of human's cognition,and thus might supplement the mfMRI in observing participants'subconscious ***,there are very few studies on how to effectively integrate the multimodal information to strengthen the performance by a unified ***:A fusion approach with mfMRI and eye tracking,based on convolution with edge-node switching in graph neural networks(CensNet),is proposed in this ***:In this graph model,participants are designated as nodes,mfMRI derived functional connectivity as node features,and different eye-tracking features are used to compute similarity between participants to construct heterogeneous graph *** taking multiple graphs as different channels,we introduce squeeze-and-excitation attention module to CensNet(A-CensNet)to integrate graph embeddings from multiple channels into ***:The proposed model outperforms those using a single modality and single channel,and state-of-the-art ***:The results indicate that brain functional activities and eye behaviors might complement each other in interpreting trait-like phenotypes.

关键词： functional connectivity naturalistic stimulus eye movement CensNet attention

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碳热还原氮化法结合泡沫前驱体制备超细氮化铝粉体（英文）

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无机材料学报 2019年第10期34卷 1123-1127页

作者：茅茜茜徐勇刚毛小建张海龙李军王士维中国科学院上海硅酸盐研究所高性能陶瓷和超微结构国家重点实验室上海200050 中国科学院上海硅酸盐研究所中国科学院光功能无机材料重点实验室上海200050 中国科学院大学北京100049

本研究使用改良的碳热还原氮化法合成超细氮化铝粉体。以γ氧化铝和蔗糖作为铝源和碳源,先预处理制备成多孔泡沫,再通过碳热还原氮化法合成氮化铝粉体。反应过程和产物通过X射线衍射分析、SEM和TEM确定。X射线衍射分析表明整个反应过程... 详细信息

本研究使用改良的碳热还原氮化法合成超细氮化铝粉体。以γ氧化铝和蔗糖作为铝源和碳源,先预处理制备成多孔泡沫,再通过碳热还原氮化法合成氮化铝粉体。反应过程和产物通过X射线衍射分析、SEM和TEM确定。X射线衍射分析表明整个反应过程不存在氧化铝的相转变。高分辨透射电子显微镜显示γ-Al2O3.粒被无定型碳包裹,从而抑制了γ-Al2O3.α-Al2O3.相转变。泡沫的多孔结构促进了氮气的扩散和反应副产物的释放,使得最低反应温度降低至1450℃。SEM结果表明得到的氮化铝颗粒粒径大约为50nm。本研究合成的氮化铝粉体可用于制备高热导氮化铝陶瓷。

关键词：氮化铝泡沫粉体合成

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中国近代以来的三种民族国家设想

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西北师大学报（社会科学版） 2014年第1期51卷 33-38页

作者：王希恩中国社会科学院民族学与人类学研究所北京100081

建立民族国家是中国近代以来各种政治力量的共同追求。单一的汉族国家、各民族同化为一的国家和复合型的多元一体国家是近代以来中国的三种民族国家设想。这些设想的提出及实践基本呈现的是一种顺序递进的关系,反映了中国人在构建自己... 详细信息

建立民族国家是中国近代以来各种政治力量的共同追求。单一的汉族国家、各民族同化为一的国家和复合型的多元一体国家是近代以来中国的三种民族国家设想。这些设想的提出及实践基本呈现的是一种顺序递进的关系,反映了中国人在构建自己民族国家认识上的不断深化。就民族国家的"民族"而言,两个层次、"多元一体"是一种普遍存在。试图将两个层次的民族单一化或同一化是失败的民族国家构想;而尊重民族多样性的存在,在保留"多元"的前提下打造国家民族"一体化"才是合乎规律的追求。在民族国家建设问题上,复合型的多元一体结构是对同质化的超越,也是对民族主义错误理想的矫正。

关键词：中国民族国家民族同化多元一体民族主义

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Up-conversion luminescence of Er^(3.)and Yb^(3.)co-doped CaBi_(2)Ta_(2)O_(9) multifunctional ferroelectrics

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Journal of Advanced Dielectrics 2014年第3期4卷 12-17页

作者： Qiufeng Cao Dengfeng Peng Hua Zou Jun Li Xusheng Wang xi Yao Functional Materials Research laboratory Tongji University1239 Siping Road Shanghai 200092P.R.China

Er^(3.)and Yb^(3.)co-doped CaBi_(2)Ta_(2)O_(9)(CBT)-based bismuth layered-structure oxides were synthesized by a simple solid-state reaction *** up-conversion(UC)luminescence,dielectric and ferroelectric properties were *** strong green emission bands centered at 526 and 547nm and a weak red emission band centered at 658nm were obtained under a 980nm laser excitation at room *** emission bands originated from the radiative relaxation of Er^(3.)from 2H_(11)=2,4S_(3.=2,and 4F_(9/2) levels to the ground state 4I_(15)=2,*** the meantime,the fluorescence intensity ratio(FIR)variation of two green UC emissions at 526 and 547nm has been studied as a function of temperature in the range of 153.*** maximum sensor sensitivity obtained was 3.×10^(-4)K^(-1) at 590K,which indicated that Er^(3.)=Yb^(3.)co-doped CBT ceramic is a promising candidate for applications in optical high temperature sensor.

关键词： Aurivillius-type bismuth layered-structure ferroelectrics up-conversion luminescence sensor fluorescence intensity ratio

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Ginsenoside Rg1 improves anti-tumor efficacy of adoptive cell therapy by enhancing T cell effector functions

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Blood Science 2023年第3期5卷 170-179页

作者： Yue Liu Lingna An Chengfei Yang xiaoqi Wang Ruihao Huang xi Zhang Medical Center of Hematology Xinqiao HospitalState Key Laboratory of TraumaBurn and Combined InjuryArmy Medical UniversityChongqing 400037China department of Urology Xinqiao HospitalArmy Military Medical UniversityChongqing 400037China Jinfeng laboratory Chongqing 401329 China

Adoptive cell therapy(ACT)has emerged with remarkable efficacies for tumor *** antigen receptor(CAR)T cell therapy,as one of most promising ACTs,has achieved prominent effects in treating malignant hematological ***,the insufficient killing activity and limited persistence of T cells in the immunosuppressive tumor microenvironment limit the further application of ACTs for cancer *** studies have focused on improving cytotoxicity and persistence of T cells to achieve improved therapeutic *** this study,we explored the potential function in ACT of ginsenoside Rg1,the main pharmacologically active component of *** introduced Rg1 during the in vitro activation and expansion phase of T cells,and found that Rg1 treatment upregulated two T cell activation markers,CD69 and CD25,while promoting T cell differentiation towards a mature *** sequencing revealed that Rg1 influenced T cell metabolic reprogramming by strengthening mitochondrial *** co-cultured with tumor cells,Rg1-treated T cells showed stronger cytotoxicity than untreated ***,adding Rg1 to the culture endowed CAR-T cells with enhanced anti-tumor *** study suggests that ginsenoside Rg1 provides a potential approach for improving the anti-tumor efficacy of ACT by enhancing T cell effector functions.

关键词： Anti-tumor efficacy Adoptive cell therapy CAR-T Ginsenoside Rg1 Metabolic regulation

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低温冻结状态下岩石的变形特性及力学行为研究

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兰州理工大学学报 2022年第2期48卷 21-27页

作者：席新林中铁第一勘察设计院集团有限公司甘肃兰州730000

为研究冻土地区不同含水状态下冻结岩石的力学行为,对凝灰岩和玄武岩冻土试件进行了常温20℃和低温-20℃下的单轴压缩试验和巴西劈裂试验.通过观察其变形行为和声发射活动,研究了其断裂破坏过程以及饱水率对材料强度和变形性能的影响.... 详细信息

为研究冻土地区不同含水状态下冻结岩石的力学行为,对凝灰岩和玄武岩冻土试件进行了常温20℃和低温-20℃下的单轴压缩试验和巴西劈裂试验.通过观察其变形行为和声发射活动,研究了其断裂破坏过程以及饱水率对材料强度和变形性能的影响.结果表明,冻结岩石的破裂过程分为以下几个阶段:Ⅰ阶段为裂纹气孔闭合;Ⅱ阶段为弹性变形;Ⅲ阶段为裂缝起裂与稳定裂缝扩展;Ⅳ阶段为裂缝不稳定扩展.同时,Ⅲ阶段开始处的应力水平随着饱水率的增加而增加.峰值应力强度和应变均随着饱水率的增加而增加,它们之间的关系可以用直线来近似表示.岩石脆性度随饱水率的增加而降低,间接抗拉强度对饱水率的影响比单轴抗压强度更敏感.

关键词：冻结岩石饱水率抗压强度抗拉强度变形声发射破坏过程

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法律视角下数据主权的理念解构与理性重构

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中国流通经济 2022年第7期36卷 118-128页

作者：陈曦笛清华大学法学院北京市100081

随着全球经济向数字驱动模式逐步转型,围绕数据获取和利用而在科技、政治、法律等维度展开的国际数据竞争愈演愈烈,数据主权化成为各国对特定范围内数据主张本国权利优越性的主要理据。然而,数据主权在法律视角下的意涵尚未得到充分澄清... 详细信息

随着全球经济向数字驱动模式逐步转型,围绕数据获取和利用而在科技、政治、法律等维度展开的国际数据竞争愈演愈烈,数据主权化成为各国对特定范围内数据主张本国权利优越性的主要理据。然而,数据主权在法律视角下的意涵尚未得到充分澄清,作为政治话语的数据主权向法律话语的转化,在理论和实践层面均存在困难。一方面,数据不具有作为国家主权客体的适格性,且数据主权化会突破国家主权概念的最大边界,易对既已建立的国际法理论和制度框架造成不必要冲击;另一方面,以国家主权模式控制数据会忽视主权本身的建构性特点,不仅难以走出数据权属模糊以及数据跨境逃逸的现实困境,反而会导致数据权属相关矛盾激化,缺乏实际意义。为平衡国家安全需求与数字大国愿景两个向度的利益诉求,我国应在推动数据主权化的同时,基于我国的现实和需求,采取进取而克制的总体管辖策略,以管辖事实固化和拓展数据权利;合理调适安全利益与个人权益二元管辖架构,以理顺我国数据治理逻辑;妥善协调数据国内规制与国际共治两个层次的微妙互动,以在积累国际数据治理经验的同时,确保我国管辖实践与国际规则一致。

关键词：数据主权国家主权数据跨境流动数据管辖权国际共治

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Functional MRI study of mild Alzheimer＇s disease using amplitude of low frequency fluctuation analysis

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Chinese Medical Journal 2012年第5期125卷 858-862页

作者： xi Qian ZHAO xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong department of Radiology Tongji Hospital of Tongji UniversityShanghai 200065 China department of Neurology Huashan Hospital of Fudan UniversityShanghai 200040 China state Key laboratory of Cognitive Neuroscience and Learning Beijing Normal University Beijing 100875 China

Background Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer＇s disease （AD） patients. However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The purpose of this study was to explore the functional brain changes in AD patients by measuring the amplitude of the blood oxygenation level dependent （BOLD） functional MRI （fMRI） signals.

关键词： Alzheimer's disease resting-state functional MRI amplitude of low frequency fluctuation

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Ultra-dense planar metallic nanowire arrays with extremely large anisotropic optical and magnetic properties

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Nano Research 2018年第7期11卷 3519-3528页

作者： Qi Jia xin Ou Manuel Langer Benjamin Schreiber Jorg Grenzer Pablo F. Siles Raul D. Rodriguez Kai Huang Ye Yuan Alireza Heidarian Rene Hubner Tiangui You Wenjie Yu Kilian Lenz Jurgen Lindner xi Wang Stefan Facsko Helmholtz-Zentrum Dresden-Rossendorf Institute of Ion Beam Physics and Materials Research Bautzner Landstr. 400 01328 Dresden Germany state Key laboratory of Functional Material for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Shanghai 200050 China Technische Universitat Chemnitz ReichenhainerstraBe 70 09107 Chemnitz Germany university of Chinese Academy of Sciences Beijing 100049 China Tomsk Polytechnic university 30 Lenin Ave. 634050 Tomsk Russia

A nanofabrication method for the production of ultra-dense planar metallic nanowire arrays scalable to wafer-size is presented. The method is based on an efficient template deposition process to grow diverse metallic nanowire arrays with extreme regularity in only two steps. First, Ⅲ-Ⅴ semiconductor substrates are irradiated by a low-energy ion beam at an elevated temperature, forming a highly ordered nanogroove pattern by a ＂reverse epitaxy＂ process due to self-assembly of surface vacancies. Second, diverse metallic nanowire arrays （Au, Fe, Ni, Co, FeAl alloy） are fabricated on these Ⅲ-Ⅴ templates by deposition at a glancing incidence angle. This method allows for the fabrication of metallic nanowire arrays with periodicities down to 45 nm scaled up to wafer-size fabrication. As typical noble and magnetic metals, the Au and Fe nanowire arrays produced here exhibited large anisotropic optical and magnetic properties, respectively. The excitation of localized surface plasmon resonances （LSPRs） of the Au nanowire arrays resulted in a high electric field enhancement, which was used to detect phthalocyanine （CoPc） in surface-enhanced Raman scattering （SERS）. Furthermore, the Fe nanowire arrays showed a very high in-plane magnetic anisotropy of approximately 412 mT, which may be the largest in-plane magnetic anisotropy field yet reported that is solely induced via shape anisotropy within the plane of a thin film.

关键词： self-assembly metallic nanowire array reverse epitaxy magnetic anisotropy anisotropic dieledric function

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Two New Compounds from Schisandra propinqua ***

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Natural Products and Bioprospecting 2017年第3期7卷 257-262页

作者： Miao Liu Zheng-xi Hu Yuan-Qing Luo Min Zhou Wei-Guang Wang xiao-Nian Li Xue Du Jian-xin Pu Han-Dong Sun state Key laboratory of Phytochemistry and Plant Resources in West china Kunming Institute of BotanyChinese Academy of SciencesKunming 650201People’s Republic of China university of Chinese Academy of Sciences Beijing 100049People’s Republic of China Hubei Key laboratory of Natural Medicinal Chemistry and Resource Evaluation School of PharmacyTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030People’s Republic of China

Schisanpropinoic acid(1),a new bergamotane sesquiterpenoid,and schisanpropinin(2),a new tetrahydrofuran lignan with a rare epoxyethane unit,were identified from the stems and leaves of Schisandra propinqua *** structures were determined based on comprehensive spectroscopic and mass spectrometric *** absolute configuration of 1 was determined by X-ray *** 1 and 2 were tested for their cytotoxic activity against five human tumor cell lines.

关键词： Schisandra propinqua var.propinqua Bergamotane-type sesquiterpenoid Lignan Absolute configuration Cytotoxicity

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