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In-hospital outcomes in COVID-19 patients with non-alcoholic fatty liver disease by severity of obesity:Insights from national inpatient sample 2020

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World Journal of Hepatology 2024年第6期16卷 912-919页

作者： Sashwath srikanth Vibhor Garg Lakshmi Subramanian Jyoti Verma Hansika Sharma Harroop Singh Klair Shrenil A Kavathia Jithin Kolli Teja Nikhil Sai Vasireddy Kumar Anmol Dhanush Kolli Shruti Sanjay Bodhankar Sobya Hashmi Shaylika Chauhan Rupak Desai Department of Medicine ECU Health Medical CenterGreenvilleNC 27834United States Department of Medicine Jacobi Medical Center/Albert Einstein College of MedicineBronxNY 10461United States Department of Medicine North Alabama Medical CentreFlorenceAL 35630United States Department of General Medicine Gandhi Medical CollegeSecunderabad 500003TelanganaIndia Department of Medicine Government Medical CollegePatiala 147001PunjabIndia Department of Medicine B.J.Medical CollegeAhmedabad 380016GujaratIndia Department of Medicine JSS Medical CollegeMysore 570015KarnatakaIndia Department of Internal Medicine Gandhi Medical CollegeSecunderabad 500003TelanganaIndia Department of Medicine Kasturba Medical CollegeManipal 575001KarnatakaIndia Clinical Extern Department of Internal MedicineBeaumont HospitalDearbornMI 48124United States Department of Internal Medicine Geisinger Health SystemWilkes-BarrePA 18702United States Independent Researcher AtlantaGA 30079United States

BACKGROUND Non-alcoholic fatty liver disease(NAFLD)increases the risk of cardiovascular diseases independently of other risk ***,data on its effect on cardiovascular outcomes in coronavirus disease 2019(COVID-19)hospitalizations with varied obesity levels is *** management and patient care depend on understanding COVID-19 admission results in NAFLD patients with varying obesity *** To study the in-hospital outcomes in COVID-19 patients with NAFLD by severity of *** COVID-19 hospitalizations with NAFLD were identified using International Classification of Disease-10 CM codes in the 2020 National Inpatient Sample *** and Obesity Classes Ⅰ,Ⅱ,and Ⅲ(body mass index 30-40)were *** adverse cardiac and cerebrovascular events(MACCE)(all-cause mortality,acute myocardial infarction,cardiac arrest,and stroke)were compared between *** regression analyses adjusted for sociodemographic,hospitalization features,and *** Our analysis comprised 13260 hospitalizations,7.3% of which were overweight,24.3% Class Ⅰ,24.1% Class Ⅱ,and 44.3% Class Ⅲ.Class Ⅲ obesity includes younger patients,blacks,females,diabetics,and hypertensive *** multivariable logistic analysis,Class Ⅲ obese patients had higher risks of MACCE,inpatient mortality,and respiratory failure than Class Ⅰ obese *** Ⅱ obesity showed increased risks of MACCE,inpatient mortality,and respiratory failure than Class I,but not *** obesity classes had non-significant risks of MACCE,inpatient mortality,and respiratory failure compared to the overweight *** Class Ⅲ obese NAFLD COVID-19 patients had a greater risk of adverse outcomes than class Ⅰ.Using the overweight group as the reference,unfavorable outcomes were not significantly *** obesity had a greater risk of MACCE regardless of the referent group(overweight or Class Ⅰ obese)compared to overweight NAFLD patients admitte

关键词： Non-alcoholic fatty liver disease Obesity Obese Body mass index Major adverse cardiac and cerebrovascular events Mortality Acute myocardial infarction Cardiac arrest Stroke

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南瓜种质资源遗传变异、遗传力和遗传进度研究

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中国瓜菜 2018年第2期31卷 35-37页

作者： Mekala srikanth Bharad S G Thulasiram L B Potdukhe N R 张桂兰(编译) Department of Horticulture Dr.Panjabrao Deshmukh Krishi VidyapeethAkola-444 001MaharashtraIndia 中国农业科学院郑州果树研究所郑州450000

对南瓜3个主要栽培种基因型遗传变异性、遗传力和遗传进度进行分析和评价。方差分析结果表明,所研究的所有性状在基因型间差异显著。调查结果显示,所有性状中表型变异系数高于基因型变异系数,表明这些性状的表达受环境调控的影响。其中9... 详细信息

对南瓜3个主要栽培种基因型遗传变异性、遗传力和遗传进度进行分析和评价。方差分析结果表明,所研究的所有性状在基因型间差异显著。调查结果显示,所有性状中表型变异系数高于基因型变异系数,表明这些性状的表达受环境调控的影响。其中90天蔓长、果腔大小、单果种粒数、果皮厚度和单蔓结果数的遗传变异系数及表型变异系数最高。遗传力概括估计,果腔最高(84.80%),其次是节间长度(76.90%)和每hm2果实产量(73.60%)。果腔性状遗传进度最高(百分数平均值)。分析结果表明,所有性状的遗传进度变异范围较大(3.44%～72.32%)。因此,可以选择具有优良遗传特征的、具有较高遗传距离的优良基因型选择杂交方案,并识别不同性状的最佳基因,以培育南瓜新的优良杂交品种。

关键词：南瓜遗传变异遗传力遗传进度

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Are Truckers Being over Stigmatized as HIV Carriers in India? Evidences from Behavioral and Biological Cross-Sectional Surveys among Clients of Female Sex Workers

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Open Journal of Preventive Medicine 2015年第3期5卷 85-91页

作者： Damodar Sahu Sowmya Ramesh Ram Manohar Mishra K. srikanth Reddy Reena Bharadwaj Niranjan Saggurti Arvind Pandey Mandar Mainkar Bitra George National Institute of Medical Statistics ICMR New Delhi India Population Council New Delhi India National AIDS Research Institute Pune India FAMILY Health International New Delhi India

This paper examines whether truckers have been over-stigmatized as HIV carriers in the country. Data were taken from cross-sectional surveys of clients of female sex workers conducted in 2006-2007 in 12 districts of the country. A total 4822 clients of female sex workers were covered in the survey. Low-income skilled/semi-skilled men, including non-agricultural/casual labor, and petty businessmen/small shop owners, have the largest share in the clients’ population. There was no significant difference between truckers and other sub-group of clients’ population in terms of consistent condom use with female sex workers and prevalence of HIV or STI. These evidences suggest that the contribution of truckers in HIV epidemic in India might to similar to other sub-groups of clients’ population. Thus, truckers might have been over-stigmatized as HIV carriers in the country. However, there is no doubt that truckers constitute an extremely important target group for the HIV prevention programs and these efforts must be continued to prevent new HIV infections in the country.

关键词： Clients Truckers Sex Workers India

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Cementing the BRICS

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Beijing Review 2016年第43期59卷 22-22页

作者： srikanth Kondapalli the School of International Studies Jawaharlal Nehru University

The Eighth BRICS Summit, bringing together leaders from Brazil, Russia, India, China and South Africa, washeld in the Indian state of Goa in mid-Oc- tober. The meeting further consolidated coordination between these f... 详细信息

关键词：金砖国家领导人治理问题俄罗斯印度

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二甲双胍单药控制不良的2型糖尿病患者联合应用任意非胰岛素类降糖药可同等程度降低糖化血红蛋白水平，但对体重和低血糖风险的影响不同

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英国医学杂志中文版 2011年第5期14卷 304-305页

作者： srikanth Bellary 许建萍（译）肖新华（校） srikanth Bellary Heart of England NHS Foundation Trust Bordesley Green EastBirmingham B95SSUK 北京协和医院内分泌科

内容当前指南推荐二甲双胍作为2型糖尿病患者的起始治疗。随着时间的推移，2型糖尿病患者B细胞功能呈进行性下降，大多数患者需要联合治疗。目前可供选择的二线治疗用药种类很多，但尚缺乏直接比较这些药物疗效的研究。因此，对于二线... 详细信息

内容当前指南推荐二甲双胍作为2型糖尿病患者的起始治疗。随着时间的推移，2型糖尿病患者B细胞功能呈进行性下降，大多数患者需要联合治疗。目前可供选择的二线治疗用药种类很多，但尚缺乏直接比较这些药物疗效的研究。因此，对于二线治疗用药的选择方法尚不清楚。在此荟萃（meta）分析中，Phung及其同事致力于该重要问题，评价了目前可获得的非胰岛素类降糖药的疗效。

关键词： 2型糖尿病胰岛素类二甲双胍血红蛋白水平降糖药患者联合应用控制不良

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Prosthetic cardiac valves

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国际内科双语杂志（中英文） 2007年第4期7卷 57-61页

作者： David E Pontefract srikanth S lyengar Clifford W Barlow 英国南安普敦Wessex心胸科医院英国南安普敦Wessex心胸科医院心胸外科英国南安普敦总医院的顾问心胸外科

在过去的30年里,人工心脏瓣膜置换术的数量一直呈稳步增长;全世界每年置换的瓣膜数量超过了225 000个,其中在英国置换的数量超过8000个.

关键词：人工心瓣膜心脏病手术治疗外科学

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Amniotic membrane as a potent source of stem cells and a matrix for engineering heart tissue

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Journal of Biomedical Science and Engineering 2013年第12期6卷 1178-1185页

作者： Julio Cesar Francisco Ricardo Correa Cunha Rossana Baggio Simeoni Luiz Cesar Guarita-Souza Reginaldo Justino Ferreira Ana Carolina Irioda Carolina Maria C.Oliveira Souza Garikipati Venkata Naga srikanth Soniya Nityanand Juan Carlos Chachques Katherine Athayde Teixeira de Carvalho Bioprocess Engineering and Biotechnology Department Federal University of ParanáCuritibaBrazil Cell Therapy and Biotechnology in Regenerative Medicine Research Group Pele Pequeno Príncipe InstituteCuritibaBrazil Experimental Laboratory of Institute of Biological and Health Sciences Pontificial Catholic University of Paraná(PUCPR)Rua Imaculada ConceicaoCuritibaBrazil Federal University of Technology CuritibaBrazil Department of Hematology Stem Cell Research FacultySanjay Gandhi Post-Graduate Institute of Medical SciencesLucknowIndia Laboratory of Biosurgical Research Pompidou HospitalUniversity of Paris DescartesParisFrance

Existing therapies for the treatment of chronic heart failure still have some limitations and there is a pressing need for the development of new therapeutic modalities. The amniotic membrane has been used for the treatment of various diseases, such as conjunctive defects;however, the mechanisms behind its repair functions are still unclear. Regenerative medicine is seeking newer alternatives and among them, biomaterials have emerged in recent years for developing and manipulating molecules, cells, tissues or organs grown in laboratories in order to replace human body parts. Many such materials have been used for this purpose, either synthetically or biologically, in order to provide new medical devices. This review provides a wider view of the regeneration potential of the use of amniotic membrane as a potential biomaterial to facilitate the implementation of new research in surgical procedures. Amniotic membrane appears to be an alternative source of stem cells as well as an excellent biomaterial for cell-based therapeutic applications in engineering heart tissue.

关键词： Amniotic Membrane Heart Tissue Engineering Stem Cells

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IEEE标准倡议聚焦扩展现实

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科技纵览 2023年第6期 59-59页

作者： Yu Yuan srikanth Chandrasekaran IEEE标准协会

一些观察人士认为,元宇宙是一套扩展的数字世界,将会从人们已熟悉的线上环境中发展起来,例如增强在线游戏中所使用的扩展现实体验。其他人则表示,元宇宙将带来一个去中心化的生态系统,让用户能够创建自己选择的数字资产并参与数字商务。

关键词：去中心化 IEEE标准数字资产生态系统现实体验在线游戏扩展宇宙

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