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Endovascular treatment of a ruptured pseudoaneurysm of the internal carotid artery in a patient with nasopharyngeal cancer:A case report

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World Journal of Clinical Cases 2022年第25期10卷 9121-9126页

作者： jung-soo park Hyoung Gyu Jang Department of Neurosurgery Jeonbuk National University Medical School and HospitalJeonju 54907South Korea

BACKGROUND Radiation therapy(RT)for nasopharyngeal cancer can cause several *** rare cases,an internal carotid artery pseudoaneurysm can occur,which can be *** report the experience of a nasopharyngeal cancer patient who underwent radiation therapy and subsequently developed a fatal pseudoaneurysm of the petrous internal carotid *** SUMMARY A 39-year-old man was diagnosed with nasopharyngeal cancer 2 years ago(American Joint Committee on Cancer Stage T3N2M0)and received concurrent chemoradiation *** subsequently relapsed and received *** week after the 4th cycle of chemotherapy,he was admitted to the emergency room of our hospital because of massive epistaxis accompanied by a headache.A pseudoaneurysm of the petrous internal carotid artery was confirmed by digital subtraction angiography(DSA).Stent-assisted endovascular coil embolization was performed and complete occlusion was *** pseudoaneurysm was observed on DSA after coil embolization;however,intermittent epistaxis was maintained even after coil *** seven days,a diagnostic laryngoscopy was *** bleeding occurred after aspiration of the blood clot during the laryngoscopy and the patient died of hypovolemic *** this case,epistaxis may have been a sign of pseudoaneurysm;therefore,treatment such as embolization should be performed promptly,and careful management should be undertaken after *** This case highlights a rare,serious complication of RT in nasopharyngeal cancer and how it should be recognized and treated.

关键词： Pseudoaneurysm Nasopharyngeal cancer Radiation therapy Epistaxis Carotid artery pseudoaneurysm Case report

Clinical characteristics and treatment of inflammatory bowel disease: A comparison of Eastern and Western perspectives

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World Journal of Gastroenterology 2014年第33期20卷 11525-11537页

作者： soo jung park Won Ho Kim Jae Hee Cheon Department of Internal Medicine and Institute of Gastroenerology Yonsei University College of Medicine Seoul 120-752 South Korea

Inflammatory bowel disease(IBD) is a chronic, relapsing intestinal inflammatory disorder with unidentified causes. Both environmental factors and genetic aspects are believed to be crucial to the pathogenesis of IBD. The incidence and prevalence of IBD have recently been increasing throughout Asia, presumably secondary to environmental changes. This increasing trend in IBD epidemiology necessitates specific health care planning and education in Asia. To this end, we must gain a precise understanding of the distinctive clinical and therapeutic characteristics of Asian patients with IBD. The phenotypes of IBD reportedly differ considerably between Asians and Caucasians. Thus, use of the same management strategies for these different populations may not be appropriate. Moreover, investigation of the Asian-specific clinical aspects of IBD offers the possibility of identifying causative factors in the pathogenesis of IBD in this geographical area. Accordingly, this review summarizes current knowledge of the phenotypic manifestations and management practices of patients with IBD, with a special focus on a comparisonof Eastern and Western perspectives.

关键词： Crohn's disease Ulcerative colitis Inflam-matory bowel disease Clinical characteristics Treat-ment Asia

Sex-dependent difference in the effect of metformin on colorectal cancer-specific mortality of diabetic colorectal cancer patients

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World Journal of Gastroenterology 2017年第28期23卷 5196-5205页

作者： jung Won park Jin Ha Lee Ye Hyun park soo jung park Jae Hee Cheon Won Ho Kim Tae Il Kim Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of Medicine Cancer Prevention Center Yonsei University College of Medicine

To assess factors associated with the higher effect of metformin on mortality in diabetic colorectal cancer (CRC) patients, since the factors related to the effectiveness of metformin have not been identified *** January 2000 and December 2010, 413 patients diagnosed with both stage 3/4 CRC and diabetes mellitus were identified. Patients’ demographics and clinical characteristics were analyzed. The effect of metformin on CRC-specific mortality and the interactions between metformin and each adjusted factor were *** follow-up duration was median 50 mo (range: 1-218 mo). There were 85 deaths (45.9%) and 72 CRC-specific deaths (38.9%) among 185 patients who used metformin, compared to 130 total deaths (57.0%) and 107 CRC-specific deaths (46.9%) among 228 patients who did not use metformin. In multivariate analysis, survival benefit associated with metformin administration was identified (HR = 0.985, 95%CI: 0.974-0.997, P = 0.012). Interaction test between metformin and sex after adjustment for relevant factors revealed that female CRC patients taking metformin exhibited a significantly lower CRC-specific mortality rate than male CRC patients taking metformin (HR = 0.369, 95%CI: 0.155-0.881, P = 0.025). Furthermore, subgroup analysis revealed significant differences in CRC-specific mortality between the metformin and non-metformin groups in female patients (HR = 0.501, 95%CI: 0.286-0.879, P = 0.013) but not male patients (HR = 0.848, 95%CI: 0.594-1.211, P = 0.365). There were no significant interactions between metformin and other adjusted factors on CRC-specific *** showed a strong sex-dependent difference in the effect of metformin on CRC-specific mortality in advanced stage CRC patients with diabetes.

关键词： Colorectal cancer Metformin Survival Sex

Massive Hematochezia Following Blunt Trauma in a Patient with Crohn＇s Disease： Intraluminal Bleeding without Hemoperitoneum

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Chinese Medical Journal 2016年第2期129卷 246-247页

作者： jung soo park Jin Hong Min Jun Ho Kang Yong Nam In Department of Emergency Medicine College of Medicine Chungbuk National University Hospital Chungbuk Korea

To the Editor： A 29-year-old woman arrived via ambulance to the emergency department with hematochezia 1 h after sustaining blunt abdominal trauma as a passenger in a traffic accident. The patient also had Crohn＇s d... 详细信息

关键词： woman arrived emergency department diverting ileostomy

Acute Myocardial Infarction Due to Stent Thrombosis After Administration of Intravenous Epinephrine for Anaphylaxis

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Chinese Medical Journal 2015年第19期128卷 2692-2693页

作者： jung soo park Jin Hong Min Jun Ho Kang Yong Nam In Department of Emergency Medicine Chungbuk National University HospitalCheongju-siChungbuk 361-763Republic of Korea

To the Editor：The guidelines of several collaborating organizations recommend epinephrine injection for prompt initial treatment of anaphylaxis.[1] The dose and route of administration are generally based on the severity of symptoms and the rapidity with which a response is ***,epinephrine is widely used to treat anaphylaxis,reports of severe complications such as acute coronary syndrome,arrhythmia,and intracranial bleeding are rare.

关键词： complications coronary syndrome

Spontaneous Ureteropelvic Junction Rupture Caused by a Small Distal Ureteral Calculus

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Chinese Medical Journal 2015年第22期128卷 3118-3119页

作者： Chi Heon Jeon Jun Ho Kang Jin Hong Min jung soo park Department of Emergency Medicine College of Medicine Chungbuk National University Cheongju Chungbuk 361-763 Korea

To the Editor： Spontaneous ureteral rupture is rare, and urolithiasis is the most common cause. The underlying mechanism may be the pressure around the ureteral wall due to stone impaction or a tear during the stone passage. Smaller distal stones exert higher intraureteral pressures than do larger proximal stones because of the greater length of obstructed ureter and the smaller diameter of the distal ureter.

关键词： Spontaneous urolithiasis intraureteral

Changes in peak inspiratory flow rate and peak airway pressure with endotracheal tube size during chest compression

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World Journal of Emergency Medicine 2020年第2期11卷 97-101页

作者： jung Wan Kim Jin Woong Lee Seung Ryu jung soo park Insool Yoo Yong Chul Cho Hong Joon Ahn Department of Emergency Medicine Chungnam National University HospitalJung-guDaejeonRepublic of Korea Department of Emergency Medicine College of MedicineChungnam National UniversityJung-guDaejeonRepublic of Korea

BACKGROUND:Adequate airway management plays an important role in high-quality cardiopulmonary resuscitation(CPR).Airway management is usually performed using an endotracheal tube(ETT)during ***,no study has assessed the effect of ETT size on the fl ow rate and airway pressure during ***:We measured changes in peak inspiratory fl ow rate(PIFR),peak airway pressure(Ppeak),and mean airway pressure(Pmean)according to changes in ETT size(internal diameter 6.0,7.0,and 8.0 mm)and with or without CPR.A tidal volume of 500 mL was supplied at a rate of 10 times per minute using a mechanical *** compressions were maintained at a constant compression depth and speed using a mechanical chest compression device(LUCAS2,mode:active continuous,chest compression rate:102±2/minute,chest compression depth 2–2.5 inches).RESULTS:The median of several respiratory physiological parameters during CPR was significantly different according to the diameter of each ETT(6.0 vs.8.0 mm):PIFR(32.1 L/min[30.5–35.3]vs.28.9 L/min[27.5–30.8],P<0.001),Ppeak(48.84 cmH2O[27.46–52.11]vs.27.45 cmH2O[22.53–52.57],P<0.001),and Pmean(18.34 cmH2O[14.61–21.66]vs.13.66 cmH2O[8.41–19.24],P<0.001).CONCLUSION:The changes in PIFR,Ppeak,and Pmean were related to the internal diameter of ETT,and these values tended to decrease with an increase in ETT *** airway pressures were measured in the CPR group than in the no CPR group.

关键词： Cardiopulmonary resuscitation Intratracheal intubation Airway pressure

Conventional endoscopic features are not sufficient to differentiate small, early colorectal cancer

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World Journal of Gastroenterology 2014年第21期20卷 6586-6593页

作者： Wan park Bun Kim soo jung park Jae Hee Cheon Tae Il Kim Won Ho Kim Sung Pil Hong Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of MedicineSeoul 120-752South Korea

AIM: To evaluate the depth of invasion of small, early colorectal cancers (ECCs) using conventional endoscopic features.

关键词： Colonoscopy Colorectal neoplasms Differential diagnosis

Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer

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World Journal of Gastroenterology 2014年第15期20卷 4370-4376页

作者： Bun Kim soo jung park Jae Hee Cheon Tae Il Kim Won Ho Kim Sung Pil Hong Department of Internal Medicine Institute of GastroenterologyYonsei University College of MedicineSeoul 120-752South Korea

AIM: To evaluate the clinicopathological features of colorectal cancer (CRC) with a v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) mutation and its molecular interaction with microsatellite instability (MSI) an... 详细信息

关键词： BRAF Colorectal cancer Molecular features Chemotherapy response Prognosis