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Nano Research 2024年第7期17卷 5914-5921页

作者： Chun-Ying Chen Qi-Jie Mo Fu-Zhen li Hai-li song li Zhang MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional MaterialsSchool of ChemistrySun Yat-Sen UniversityGuangzhou 510006China

Alkene hydrosilylation is one of the most concise and atom-economical methods to synthesize organosilicon ***,we reported the precise immobilization of metal single atoms(M-SAs;M=Ru,Rh,Ir,Pd,Pt,and Au)into a porphyrinic metalorganic framework(MOF)of PCN-222(PCN=porous coordination network),and then applied the resultant MOF composites of M-SAs@PCN-222 to alkene *** solvent-free conditions,Pt-SAs@PCN-222 displayed an especially high catalytic efficiency with the turnover frequency up to 119 s−1 and the maximum turnover number of 906,250 at room *** and theoretical studies revealed that there existed strong interactions between Pt-SAs@PCN-222 and the substrates,which helped to condense the substrates in the cavities of the porous *** density functional theory calculations and molecular dynamics simulations disclosed that PCN-222 could transfer electrons to Pt-SAs to enhance the silane oxidative addition and drive the reaction to proceed smoothly via Chalk–Harrod pathway.

关键词： alkene hydrosilylation single atom catalysts metal-organic frameworks precision chemistry synergistic catalysis

Mechanomedicine:From Mechanogenomics to Mechano-Immunoengineering

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医用生物力学 2024年第S1期39卷 5-6页

作者： song li Department of Bioengineering and Medicine University of CaliforniaLos AngelesCA 90095USA

Mechanobiology is a rapidly growing field that has expanded significantly over the past 40 *** have been great examples of mechanobiology research on the cardiovascular,musculoskeletal,and respiratory *** field has evolved from the system level to the organ and tissue levels,and down to the cellular and molecular levels,benefiting from scientific progress and technological developments in molecular and cell biology,biomaterials,imaging techniques,and computational ***,the interdisciplinary integration of mechanobiology with cell engineering,tissue engineering,and drug delivery has led to promising mechanomedicine applications in both therapeutics and ***,I will discuss two examples at the molecular and cellular levels:(1)mechanical regulation of epigenomics for cell reprogramming,and(2)engineering the mechanical properties of artificial antigen-presenting cells(APCs)for immune cell modulation and cancer *** memory of its identity is determined by the epigenetic state of the ***,how cells control the epigenetic state and thus cell fate is not well understood,and how mechanical factors such as surface topography,cell morphology,mechanical properties of the extracellular matrix(ECM),and the mechanical deformation of cells regulate the epigenetic state is not *** an early study,we showed that biophysical cues,in the form of parallel microgrooves on the surface of cell-adhesive substrates,can replace the effects of small-molecule epigenetic modifiers and significantly improve reprogramming efficiency from fibroblasts to induced pluripotent stem *** mechanism relies on the mechanomodulation of the cells’epigenetic state through the activity of histone deacetylase and H3 *** also showed that microtopography promotes a mesenchymal-to-epithelial transition in adult *** scaffolds with aligned fiber orientation produce effects similar to those produced by microgrooves

关键词： programming viscoelastic expanded

Effect of Biophysical Cues on Cell Reprogramming

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医用生物力学 2019年第A01期34卷 14-15页

作者： Yang song song li Department of Bioengineering University of California

Cell reprograming technologies have broad applications in cell therapy,disease modeling and drug *** reprogramming is the process of converting from one cell type into a very distantly related cell *** this direct conversion process,cells do not proceed through a pluripotent stage,which can be time-consuming and challenging due to spontaneous *** method also offers the advantage of circumventing the teratoma potential that is associated with using *** works have demonstrated that with the use of genetic manipulation,fibroblasts can be directly converted into other cell types,including neurons,cardiomyocytes,blood cell progenitors,and *** is well known that the microenvironment can directs cell fate,and in turn cells interact with or remodel their *** evidence suggests that biophysical factors such as the microtopography and mechanical property of cell adhesive substrates regulate a variety of cellular functions such as migration,proliferation and differentiation,which in turn can modulate wound healing,tissue remodeling and tumor growth,but there are limited number of studies on the roles of biophysical cues in cell reprogramming[1].Passive topographical cues offer a simple and effective method to improve reprogramming efficiency without the need for biochemical *** previous study has demonstrated that somatic cells cultured on the parallel microgrooves,which can replace the effects of small-molecule epigenetic modifiers and significantly improve the iPSCs reprogramming *** mechanism relies on the mechanomodulation of the cells’epigenetic state,specifically,an increase of histone H3 acetylation and H3K4 methylation[2].Additionally,in cardiomyocytes reprogramming study,culturing the fibroblasts on microgrooved substrate enhances the expression of cardiomyocyte genes by day 2 and improves the yield of partially reprogrammed cells at day *** combining microgrooved substra

关键词： Effect Biophysical Cues Cell Reprogramming

ADJACENT MARTIX METHOD OF IDENTIFYING ISOMORPHISM TO PLANAR KINEMATIC CHAIN WITH MULTIPLE JOINTS AND HIGHER PAIRS

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Chinese Journal of Mechanical Engineering 2006年第4期19卷 605-609页

作者： song li HUANG Yong CHENG ling Department of Mechanical Engineering Xiangtan University Xiangtan 411105 China

The adjacent matrix method for identifying isomorphism to planar kinematic chain with multiple joints and higher pairs is presented. The topological invariants of the planar kinematic chain can be calculated and compared by adjacent matrix. The quantity of calculation can be reduced effectively using the several divisions of bars and the reconfiguration of the adjacent matrix. As two structural characteristics of adjacent matrix, the number of division and division code are presented. It can be identified that two kinematic chains are isomorphic or not by comparing the structural characteristics of their adjacent matrixes using a method called matching row-to-row. This method may be applied to the planar linkage chain too. So, the methods of identifying isomorphism are unified in the planar kinematic chain that has or hasn＇t higher pairs with or without multiple joints. And it has some characters such as visual, simple and convenient for processing by computer, and so on.

关键词： Planar kinematic chain Higher pair Multiple joint Adjacent matrix Identifying isomorphism

AERODYNAMIC OPTIMIZATION DESIGN OF LOW ASPECT RATIO TRANSONIC TURBINE STAGE

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Chinese Journal of Mechanical Engineering 2006年第4期19卷 500-504页

作者： song liming li Jun FENG Zhenping Institute of Turbomachinery Xi＇an Jiaotong University Xi＇an 710049 China

The advanced optimization method named as adaptive range differential evolution （ARDE） is developed. The optimization performance of ARDE is demonstrated using a typical mathematical test and compared with the standard genetic algorithm and differential evolution. Combined with parallel ARDE, surface modeling method and Navier-Stokes solution, a new automatic aerodynamic optimization method is presented. A low aspect ratio transonic turbine stage is optimized for the maximization of the isentropic efficiency with forty-one design variables in total. The coarse-grained parallel strategy is applied to accelerate the design process using 15 CPUs. The isentropic efficiency of the optimum design is 1.6% higher than that of the reference design. The aerodynamic performance of the optimal design is much better than that of the reference design.

关键词： Turbine stage Adaptive range differential evolution (ARDE)Aerodynamic optimization Coarse-grained parallel strategy

Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors

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Chinese Chemical Letters 2012年第2期23卷 133-136页

作者： Yan liu Wu Zhong song li School of Pharmaceutical Engineering Shenyang Pharmaceutical UniversityShenyang 110016China Laboratory of Computer-Aided Drug Design&Discovery Beijing Institute of Pharmacology and ToxicologyBeijing 100850China

A short and efficient synthesis of（Z）-2-substituted-5-（4-（（2-substitued-5-oxoimidazolidin-4-ylidene）methyl）benzamido）ben-zoic acid derivatives（8a-g） as potential type of FabH inhibitors is *** structures wer... 详细信息

关键词： Tuberculosis Mycobacterium tuberculosis FabH Enzyme inhibitor Synthesis NOE

Amorphous nickel-iron oxides/carbon nanohybrids for an efficient and durable oxygen evolution reaction

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Nano Research 2017年第11期10卷 3629-3637页

作者： Bo li Shuangming Chen Jie Tian Ming Gong Hangxun Xu li song CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and Engineering University of Science and Technology of China Hefei 230026 China National Synchrotron Radiation Laboratory CAS Center for Excellence in Nanoscience University of Science and Technology of ChinaHefei 230029 China Engineering and Materials Science Experiment Center University of Science and Technology of China Hefei 230027 China

Highly efficient and durable water oxidation electrocatalysts are critically important in a wide range of clean energy technologies,including water electrolyzers and rechargeable metal-air ***,we report a novel sonochemical approach to synthesize amorphous nickel-iron oxides/carbon nanohybrids with tunable compositions for the oxygen evolution reaction （OER）.The sonochemically synthesized amorphous electrocatalysts with optimal composition exhibit a low overpotential of 290 mV at 10 mA＆#183;cm-2 and a Tafel slope of 31 mV＆#183;decade-1 in a 0.1 M KOH electrolyte,outperforming the benchmark RuO2 ***,these nanohybrids are also highly stable and remain amorphous even after prolonged *** addition to amorphism,sonochemistry endows as-prepared nickel-iron oxides/carbon nanohybrids with a simultaneously formed carbon scaffold and internal Ni（0）,which can enhance the stability and activity for the *** work demonstrates that sonochemistry is a unique method for synthesizing amorphous metal oxides toward an efficient and durable OER.

关键词： amorphous meal oxides electrocatalysis,oxygen evolution reaction,sonochemistry,X-ray absorption near edge structure

A design of inductosyn angle measurement system based on AD2S80A and FPGA 36

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A design of inductosyn angle measurement system based on AD2...

Study of the thermal influence on the dynamic characteristics of the motorized spindle system

第36届中国控制会议

作者： song li KANG Jianbing li Jing Beijing Institute of Space Mechanics ＆ Electricity

ISBN: (纸本)9781538629185

This paper introduces an inductosyn angle measurement system based on resolver-to digital converter chip AD2S80 A and *** improve the accuracy of angle measurement,a low noise signal process circuit is designed,and amalgamation and compensation of the coarse-fine channels are *** results indicate that the measurement accuracy is within 1 "by using this method,which can satisfy the system requirements of high reliability and accuracy,as well as strong anti-jamming ability.

关键词： inductosyn Amalgamation and compensation of the coarse and fine channels high measurement accuracy

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Advances in Manufacturing 2016年第4期4卷 355-362页

作者： song-Sheng li Yuan Shen Qiang He School of Mechatronic Engineering and Automation Shanghai Key Laboratory of Intelligent Manufacturing andRobotics Shanghai University Shanghai 200072People's Republic of China School of Mechanical Engineering Anyang Institute ofTechnology Anyang 455000 HenanPeople's Republic of China

The severe internal heat generation of the motorized spindle system causes uneven temperature dis- tribution, and will affect the vibration characteristics of the system. Based on the thermal analysis about the motorized spindle by finite element method （FEM）, the thermal deformations of the spindle system are calculated by the thermal structure coupling simulation, and the thermal deformations of the rotor and the bearing units are extracted to analyze the bearing stiffness changes so that the modal characteristics of the rotor can be simulated in different thermal state conditions. And then the rotor thermal deformation experiment and the modal experiment of spindle by exciting with hammer are performed. The result shows that the thermal state of the motorized spindle system has a significant influence on the natural frequency of the rotor, which can be carefully treated when a spindle system is designed.

关键词： Motorized spindle Thermal characteristic Thermal-structure coupling Modal analysis Spindlesystem

Representation Theorems for Generators of BSDEs in L^p Spaces

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Acta Mathematicae Applicatae Sinica 2012年第2期28卷 255-264页

作者： li song Feng HU Zeng-jing CHENt School of Mathematics Shandong University Jinan 250100 China School of Finance Shandong Polytechnic University Jinan 250100 China Department of Mathematics Qufu Normal University Qufu 273165 China Department of Financial Engineering Ajou University Suwon 443749 Korea

In this paper, we prove that the generator g of a class of backward stochastic differential equations （BSDEs） can be represented by the solutions of the corresponding BSDEs at point （t, y, z）, when the terminal da... 详细信息

关键词： backward stochastic differential equation generator representation theorem