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Ultra-thin light-weight laser-induced-graphene (LIG) diffractive optics

Light(Science & Applications) 2023年第7期12卷 1268-1300页

作者： Younggeun lee Mun Ji Low Dongwook Yang Han Ku Nam Truong-son Dinh le Seung Eon lee Hyogeun Han Seunghwan Kim Quang Huy Vu Hongki Yoo Hyosang Yoon Joohyung lee Suchand Sandeep Keunwoo lee Seung-Woo Kim Young-Jin Kim Department of Mechanical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daehak-roYuseong-guDaejeon 34141Republic of Korea School of Mechanical and Aerospace Engineering Nanyang Technological University(NTU)50 Nanyang Avenue639798 SingaporeSingapore Panasonic Factory Solutions Asia Pacific(PFSAP) 285 Jalan Ahmad Ibrahim639931 SingaporeSingapore Department of Aerospace Engineering Korea Advanced Institute of Science and Technology(KAlST)Daehak-roYuseong-guDaejeon 34141Republic of Korea Department of Mechanical System Design Engineering Seoul National University of Science and Technology(Seuoltech)232 Gongneung-roNowon-guSeoul 01811Republic of Korea LASER N GRAPN INC 193 Munj-roYuseong-guDaejeon 34051Republicof Korea

The realization of hybrid optics could be one of the best ways to fulfll the technological requirements of compact,light-weight,and multi-functional optical systems for modern *** diffractive lens(PDL)such as diffractive lenses,photonsieves,and metasurfaces can be patterned on ultra-thin flexible and stretchable substrates and be conformally attached on top of arbitrarily shaped *** this review,we introduce recent research works addressed to the design and manufacturing of ultra-thin graphene optics,which will open new markets in compact and light-weight optics for next-generation endoscopic brain imaging,space internet,real-time surface proflometry,and multi-functional mobile *** provide higher design flexibility,lower process complexity,and chemical-free process with reasonable investment cost,direct laser writing(DLW)of laser-induced-graphene(LIG)is actively being applied to the patterning of *** realizing the best optical performances in DLW,photon-material interactions have been studied in detail with respect to different laser parameters;the resulting optical characteristics have been evaluated in terms of amplitude and phase.A series of exemplary laser-written 1D and 2D PDL structures have been actively demonstrated with different base materials,and then,the cases are being expanded to plasmonic and holographic *** combination of these ultra-thin and light-weight PDL with conventional bulk refractive or reflective optical elements could bring together the advantages of each optical *** integrating these suggestions,we suggest a way to realize the hybrid PDL to be used in the future micro-electronics surface inspection,biomedical,outer space,and extended reality(XR)industries.

关键词： optics weight holographic

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Estimation of the Solid Waste Generation and Recycling Potential of the Hotel Sector: A Case Study in Hue City, Vietnam

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Journal of Environmental Protection 2018年第7期9卷 751-769页

作者： le Hoang son Yasuhiro Matsui Do Thi Thu Trang Nguyen Phuc Thanh Graduate School of Environmental and Life Science Okayama University Okayama Japan Danang University of Science and Technology University of Da Nang Da Nang Vietnam New Royal Village B202 1497-1 Muramatsu Tokai Village Naka-gun Ibaraki 319-1112 Japan Hitachi Zosen Corporation Tokyo Japan

This study examined the solid waste generation and recycling potential of the hotel sector in Hue City, Vietnam. The authors conducted waste measurement, waste composition, and questionnaire surveys for 45 target hotels over ten consecutive days. The waste generation rates (WGRs) by rooms, beds, guests, and workers were assessed by hotel class using the following three waste categories, considering informal waste collection: general waste (GW), separated recyclables (SRe), and separated food residue (SFR). The 5-star hotels exhibited the highest WGR per room at 1.61 kg/room/day, while 1-star hotels exhibited the lowest per-room WGR (0.39 kg/room/day). Spearman Rank correlation test revealed that hotel class and per-room, per-bed, and per-guest WGRs were significantly positively correlated (p maining in the GW were 19.3% to 38.5% and 38.0% to 57.9%, respectively. Based on the WGRs and waste composition determined in this study, the estimated total amount of waste generated was 6.88 tons/day (6.26 to 7.62 tons/day, 95% CI), of which 4.37 (64%), 2.13 (31%), and 0.38 tons/day (6%) were GW, SFR, and SRe, respectively. The recycling and composting potentials remaining in GW were 0.94 (13%) and 2.57 tons/day (37%), respectively. High-class hotels should be considered as the highest priority targets for a “reduce, reuse, recycle” (3R) promotion campaign in the future, with estimated recycling and composting potentials of 0.27 (4%) and 1.10 tons/day (16%), respectively.

关键词： Waste Generation Recycling Potential Hotel Sector Confidence Interval Estimation

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Evaluation of the Ability to Apply Near-Infrared Spectroscopy on Direct Assay of Acyclovir in Tablets

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Journal of Pharmacy and Pharmacology 2017年第12期5卷 841-849页

作者： le Dinh Chi Tran Viet Hung Bui Van Trung Doan Cao son . The Department of Analytical Chemistry and Toxicology Hanoi University of Pharmacy Hanoi 110403 Vietnam Director Institute of Drug Quality Control Ho Chi Minh City Ho Chi Minh City 712161 Vietnam The Laboratory of Physical Measurements National Institute of Drug Quality Control Hanoi 110116 Vietnam Director National Institute of Drug Quality Control Hanoi 110116 Vietnam

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In vivo anticancer activity of maesopsin 4—O— β—glucoside isolated from leaves of Artocarpus tonkinensis *** Gagnep

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 343-348页

作者： Trinh Thi Thuy Dao Duc Thien Tran Quang Hung Nguyen Thanh Tam Nguyen Thi Hoang Anh Nguyen Thi Nga Nguyen Thi Cuc le Phuong mai Tran Van Sung Domenico V.Delfino Do Thi Thao Institute of Chemistry.Vietnam Academy of Science and Technology Institute of Biotechnology Vietnam Academy of Science and Technology National Research Council Canada Measurement Science and Standards1200 Montreal RoadBuilding M-12.Ottatca.Ontario KIA OR6 Department of Medicine University of PerugiaPiazzale Gambuli.S.Andrea delle Fratte

Objective:To investigate the antitumor effect of maesopsin 4-O-β-glucoside(TAT2) isolated from the leaves of Artocarpus tonkinensis(***) *** ***:The antitumor activity of TAT2 was evaluated in lewis lung carcinoma(LLC) tumor-bearing ***/c mice had tumors induced by implantation with 2× 10~6 LLC cells into the subcutaneous right posterior ***-bearing mice were treated orally with a range of doses of TAT2 and a standard drug,*** were observed for tumor growth and mortality *** was collected to determine hematological and biochemical *** TAT2 was isolated from an ethanolic extract of *** *** structure was determined by MS and NMR spectroscopy,and identified as *** compound did not show acute toxicity at the highest dose tested(2 OIK) mg/kg body weight).TAT2 exhibited antitumor activity by decreasing tumor growth,increasing the survival rale,and ameliorating some hematological and biochemical parameters at doses of 100 and 200 mg/kg body weight(Plear antitumor *** to its bioavailability and low toxicity,and the fact that it could be isolated in a large scale from *** leaves,the compound shows promise as a potential anticancer drug.

关键词： Artocarpus tonkinensis BALB/c Hematological parameters lewis lung carcinoma Maesopsin 4-0-β-glucoside

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儿童急性淋巴细胞白血病合并卡氏肺孢子虫肺炎的临床特点和诊治分析

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中国实验血液学杂志 2022年第4期30卷 1079-1085页

作者：林少汾侯乐乐王健许吕宏刘勇麦友刚方建培周敦华中山大学孙逸仙纪念医院儿科广东广州510120

目的:探讨儿童急性淋巴细胞白血病(ALL)化疗后骨髓抑制期并发卡氏肺孢子虫肺炎(PCP)的临床特点和治疗对策,为临床医生进行早期诊断和有效治疗提供参考。方法:回顾性分析5例儿童ALL化疗后粒细胞缺乏期发生PCP的临床表现、实验室检查、影... 详细信息

目的:探讨儿童急性淋巴细胞白血病(ALL)化疗后骨髓抑制期并发卡氏肺孢子虫肺炎(PCP)的临床特点和治疗对策,为临床医生进行早期诊断和有效治疗提供参考。方法:回顾性分析5例儿童ALL化疗后粒细胞缺乏期发生PCP的临床表现、实验室检查、影像学结果以及治疗和转归。结果:5例患儿男女比例为1∶4,中位年龄5.5(2.9-8)岁。5例患儿均为诱导缓解化疗后粒细胞缺乏期间出现PCP,临床表现缺乏特异性,主要表现为高热、气促、呼吸费力,咳嗽不剧烈,2例出现肺部湿啰音,3例双肺无啰音。实验室检查结果提示,C反应蛋白(CRP)、血清降钙素原(PCT)、(1,3)⁃β⁃D⁃葡聚糖(BDG)、乳酸脱氢酶(LDH)以及炎症因子IL⁃2R、IL⁃6、IL⁃8均升高;胸部CT表现为双肺弥漫多发斑片状密度增高影;均通过高通量测序技术在肺泡灌洗液或深部痰中检出卡氏肺孢子虫。所有患儿疑诊PCP即停化疗,并予复方磺胺甲恶唑片联合卡泊芬净抗卡氏肺孢子虫治疗和甲基强的松龙抗炎,同时予粒细胞刺激因子、丙种球蛋白等支持治疗;期间所有儿童均因呼吸窘迫转入PICU,予无创或有创机械通气治疗。4例患儿治愈,1例患儿死亡。结论:ALL患儿出现高热、呼吸困难、LDH及BDG升高,肺部弥漫斑片影或实变时,应高度怀疑PCP,尽快完善呼吸道标本的病原体检测。TMP/SMZ是抗PCP的一线用药,卡泊芬净静滴联合TMP/SMZ口服治疗NH⁃PCP可能有更好的疗效,糖皮质激素辅助治疗中重度NH⁃PCP可能使患者获益。

关键词：肺孢子虫肺炎儿童急性淋巴细胞白血病临床特点诊断治疗

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Characteristics of the gene encoding pyrroline-5-carboxylate synthase(P5CS) in Vietnamese soybean cultivars(Glycine max ***)

Characteristics of the gene encoding pyrroline-5-carboxylate...

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International Conference on Biology, Environment and Chemistry（ICBEC 2010）

作者： Chu Hoang Mau Nguyen Thi Thuy Huong Chu Hoang Lan Nguyen Tuan Anh le Van son Chu Hoang Ha Dept.of Genetics Faculty of Biology Thainguyen University Dept.of Genetics Faculty of Biology Vietnam National University of Science Dept.of Environment Faculty of Agricultural Environment Thainguyen University Lab.of Plant Cell Biotechnology Institute of Biotechnology

ISBN: (纸本)9789810886424

This research evaluates the ability of six soybean local cultivars and a control cultivar(DT84) to tolerate severe *** this research,SL5 and SL6 have the most stress tolerance while DT84 and SL1 have the least stress *** have isolated P5CS gene as it relates to stress tolerance by using PCR with *** results show that the size of the P5CS gene of the studied cultivars is 2,148 bp,which encodes for 715 amino *** these proteins are compared with the P5CS proteins of the other species,the result shows that the isolated P5CS proteins have a higher identity than other bean *** are located on the same branch of the phylogenetic ***(Pro) is one of the most accumulated osmolytes in salinity and water deficit conditions in plants.P5CS is a key regulatory enzyme involved in prolin biosynthesis in plants and is subject to feedback inhibition by *** conserved aspartate residue at 126 and the phenylalanine at 129 are involved in the feedback inhibition by Pro binding.A gene encoding a feedback insensitive P5CS enzyme was obtained by mutating the P5CS *** mutation was due to a change of an aspartate at position 125 to alanine in the *** mutated gene was cloned in pBT vector and *** gene will be transfered to plants to increase the level of proline overproduction and to enhance the drought tolerance ability.

关键词： drought,Glycine max,point mutation,P5CS,proline.

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砂土中桩靴贯入深度对自升式风电安装船水平承载特性影响的试验研究

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南方能源建设 2023年第4期10卷 1-10页

作者：王凯武宗豪韩若朗乐丛欢麦志辉吴韩中山大学海洋工程与技术学院广东珠海519082 天津大学水利工程仿真与安全国家重点实验室天津300350 广东精铟海洋工程股份有限公司广东佛山528000 广东联塑精铟科技有限公司广东佛山528226

[目的]自升式风电安装船作为海上风电开发中的重要施工设备,研究其在位状态下的承载性能对于保障风电安装船作业安全尤为重要。[方法]文章以自升式安装船为研究对象,结合室内模型试验和有限元法开展了均质砂土中4种不同的桩靴贯入深度... 详细信息

[目的]自升式风电安装船作为海上风电开发中的重要施工设备,研究其在位状态下的承载性能对于保障风电安装船作业安全尤为重要。[方法]文章以自升式安装船为研究对象,结合室内模型试验和有限元法开展了均质砂土中4种不同的桩靴贯入深度下的水平承载性能以及周围土压力变化规律研究。[结果]研究表明:随着贯入深度的增加,自升式安装船的水平承载力呈近似线性增长趋势,贯入深度为10 cm较贯入深度4 cm水平承载力增加了38.02%,其对应的水平位移同样呈现增加的趋势,在水平荷载作用下,桩靴的承载模式表现为临载侧桩靴受压,背载侧桩靴受拉。桩靴表面同侧土压力变化规律一致,当贯入深度为10 cm时,临载侧桩靴底的土压力变化最大值为38.37 kPa,较贯入深度为4 cm时增大了126.2%。且临载侧桩靴下表面和背载侧桩靴上表面的土压力变化较大。[结论]水平荷载作用下自升式安装船的受力模式为拉压模式,且砂土中桩靴贯入深度的增加,能显著提高水平承载性能,为保障风电安装船的安全和作业能力,需保障桩靴的贯入足够的深度。

关键词：砂土自升式安装船贯入深度水平承载特性有限元模型

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基于ALOS影像的黄土丘陵区典型流域景观空间格局

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应用生态学报 2011年第3期22卷 741-747页

作者：买凯乐张文辉西北农林科技大学西部环境与生态教育部重点实验室陕西杨凌712100

基于ALOS卫星的中、高分辨率遥感影像,解译出与燕沟流域(燕沟流域是黄土丘陵沟壑区的典型小流域)生态恢复、农业生产、生活密切相关的7种景观类型,利用景观多样性和景观异质性两类指数分析了2007年燕沟流域景观格局和景观功能,并结合数... 详细信息

基于ALOS卫星的中、高分辨率遥感影像,解译出与燕沟流域(燕沟流域是黄土丘陵沟壑区的典型小流域)生态恢复、农业生产、生活密切相关的7种景观类型,利用景观多样性和景观异质性两类指数分析了2007年燕沟流域景观格局和景观功能,并结合数字高程模型(DEM)数据,对燕沟流域整体和局部的土地景观格局合理性进行评价.结果表明:燕沟流域的主导景观类型为灌丛和林地,且主要分布在大于25°的坡面上;研究区景观斑块分维数为1.09,景观空间格局稳定;生态防护、生产经济和生活服务型景观的面积比例约为23∶9∶1;燕沟流域的相对合理度为0.76,景观整体布局较合理,但半阴坡、海拔900 m以下区域的土地利用合理度较低,其合理度分别为0.74和0.02.

关键词：黄土丘陵区小流域 ALOS影像数字高程模型土地利用合理度景观功能

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Strategic Synthesis of Antimicrobial Glycopeptides and Peptidoglycans

Strategic Synthesis of Antimicrobial Glycopeptides and Pepti...

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第二届糖合成化学青年学术研讨会

作者： Jingxi He Hua Chai kim le mai Hoang 刘学伟 Division of Chemistry and Biological Chemistry Nanyang Technological University

Glycopeptides and glycoproteins play vital roles in a wide array of biological activities including cell-cell adhesion, cell differentiation, cell growth and tumour metastasis. In addition, a host of major illnesses such as autoimmune diseases, infectious diseases and cancer are caused by aberrant protein glycosylation. Consequently, the development of new glycopeptides-based vaccines, diagnostics and therapeutics has gained significant interests, stimulating the study of glycopeptide synthesis. Here, a practical approach towards N-glycopeptide synthesis using an auxiliary-mediated dual native chemical ligation（NCL） is presented. The first NCL connects an N-linked glycosyl auxiliary to the thioester side chain of an N-terminal aspartate oligopeptide. This intermediate undergoes a second NCL with a Cterminal thioester peptide. Mild deprotection provides the desired N-glycopeptide. The flexibility and systematic control of our method clearly have significant advantages over preceding ones and present a major step forward in glycoscience. Taking into consideration of the previous approaches, our method offers an attractive and practical procedure to N-glycopeptide that does not require cysteine residue, allowing for straightforward glycosylation and ligation at aspartic acid terminal. The auxiliary-linked glycosyl donor can be obtained from readily available glycosyl azide. Our method can leverage modern techniques such as intein-mediated ligation or recombinant expression to gain access to peptides of virtually any length and order. In addition, quick access to polymeric peptidoglycans will also be presented.

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采用间接法建立BV-VCA-IgA和EBV-EA-IgA定量检测的参考区间

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国际医药卫生导报 2023年第10期29卷 1385-1391页

作者：麦东媚沈乐谭俊青广东省第二中医院检验科广州510000 广东江南医院检验科广州510000

目的采用广东省第二中医院实验室信息管理系统(LIS)中的数据,以间接法来建立本实验室EB病毒衣壳抗原IgA抗体(EBV-VCA-IgA)和EB病毒早期抗原IgA抗体(EBV-EA-IgA)的生物参考区间。方法对2020年8月至2021年7月广东省第二中医院LIS数据进行... 详细信息

目的采用广东省第二中医院实验室信息管理系统(LIS)中的数据,以间接法来建立本实验室EB病毒衣壳抗原IgA抗体(EBV-VCA-IgA)和EB病毒早期抗原IgA抗体(EBV-EA-IgA)的生物参考区间。方法对2020年8月至2021年7月广东省第二中医院LIS数据进行回顾性分析,选取2160名(男998名,女1162名)20~100岁且血清天冬氨酸转氨酶(AST)、血清丙氨酸转氨酶(ALT)、总胆红素(T-BILI)、直接胆红素(D-BILI)、间接胆红素(I-BILI)、血清肌酐(CR)及尿素氮(BUN)结果正常的健康体检人群的EBV-VCA-IgA和EBV-EA-IgA检测结果,对检测结果进行性别与年龄分组。使用Kolmogorov Smirnov(K-S)检验对各组别进行正态性检验,P>0.05视为正态分布,P<0.05视为非正态分布。对于非正态分布数据,剔除大于P_(25)-3×IQR及小于P_(75)+3×IQR数据。剔除后的数据进行非参数检验,分析各组间的差异。利用P_(2.5)~P_(97.5)区间来建立EBV-VCA-IgA及EBV-EA-IgA的生物参考区间,并对参考区间进行验证。结果不同性别间的EBV-VCA-IgA参考区间差异有统计学意义(P<0.001),不同年龄组间的EBV-VCA-IgA差异无统计学意义(P=0.087)。EBV-EA-IgA不同性别间差异无统计学意义(P=0.127),不同年龄组间差异有统计学意义(P=0.004)。其中,EBV-EA-IgA 20~50岁组和≥50~70岁组分别与≥70岁组比较差异有统计学意义(P=0.002,P<0.001),EBV-EA-IgA 20~50岁组和≥50~70岁组比较差异没有统计学意义(P=0.043),合并为1组(20~70岁)建立参考区间,且与≥70岁组比较差异有统计学意义(P=0.001)。因此,EBV-VCA-IgA参考区间:男性为0.34~3.88 AU/ml、女性为0.32~3.71 AU/ml;EBV-EA-IgA参考区间:20~70岁组为0.01~1.39 AU/ml、≥70岁组为0.01~1.52 AU/ml。结论利用间接法为本实验室建立EB-VCA-IgA和EB-EA-IgA的生物参考区间,能为临床对鼻咽癌等EB病毒导致的疾病诊断提供更为准确的结果。

关键词： EB病毒间接法生物参考区间 EB病毒衣壳抗原抗体 EB病毒早期抗原抗体

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