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Advanced nerve regeneration enabled by neural conformal electronic stimulators enhancing mitochondrial transport

Bioactive Materials 2024年第9期39卷 287-301页

作者： Hao Bai Siqi Zhang Huiran Yang Jing Wang Hongli Chen Jia Li Lin Li Qian Yang Bo Peng Ziyi Zhu siyuan ni Keyin Liu Wei Lei Tiger H.Tao Yafei Feng Department of Orthopedics Xijing HospitalThe Fourth Military Medical UniversityXi’an710032China State Key Laboratory of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai200050China Key Laboratory of Aerospace Medicine of the Ministry of Education School of Aerospace MedicineFourth Military Medical UniversityXi’anChina The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen361005FujianChina Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical UniversityXi’an710072PR China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing100049China School of Physical Science and Technology ShanghaiTech UniversityShanghai200031China Institute of Brain-Intelligence Technology Zhangjiang LaboratoryShanghai200031China

Addressing peripheral nerve defects remains a significant challenge in regenerative *** as the gold-standard management,however,are hindered by limited availability and potential *** recent studies report the potential of wireless electronic system for nerve defects ***,few has met clinical needs for inadequate electrode precision,poor nerve entrapment andinsufficient bioactivity of the matrix ***,we present an advanced wireless electrical nerve stimulator,based on water-responsive self-curling silk membrane with excellent bioabsorbable and *** constructed a unique bilayer structure with an oriented pre-stretched inner layer and a generalsilk membrane as outer *** wetting,the simultaneous contraction of inner layer and expansion of outerlayer achieved controllable super-contraction from 2D flat surface to 3D structural *** enablesshape-adaptive wrapping to cover around nerves,overcomes the technical obstacle of preparing electrodes on theinner wall of the conduit,and prevents electrode breakage caused by material expansion in *** use of forkcapacitor-like metal interface increases the contact points between the metal and the regenerating nerve,solvingthe challenge of inefficient and rough electrical stimulation methods in the *** developed electronicstimulator is effective in restoring 10 mm rat sciatic nerve defects comparable to autologous *** underlyingmechanism involves that electric stimulation enhances anterograde mitochondrial transport to matchenergy *** newly introduced device thereby demonstrated the potential as a viable and efficaciousalternative to autografts for enhancing peripheral nerve repair and functional recovery.

关键词： Silk materials Electronic stimulator Structural reconfiguration Peripheral nerve regeneration Mitochondrial transport

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基于轮换策略的异构云资源分配算法

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计算机工程 2021年第6期47卷 44-51,67页

作者：倪思源扈红超刘文彦梁浩郑州大学中原网络安全研究院郑州450000 中国人民解放军战略支援部队信息工程大学郑州450000

云计算以其按需索取、按需付费、无需预先投资的优势给用户带来极大的便利,然而静态、单一的云计算环境容易成为网络攻击的目标,给用户带来较大的安全风险。动态的虚拟机部署策略和异构的云基础设施在提升云计算环境安全性的同时会降低... 详细信息

云计算以其按需索取、按需付费、无需预先投资的优势给用户带来极大的便利,然而静态、单一的云计算环境容易成为网络攻击的目标,给用户带来较大的安全风险。动态的虚拟机部署策略和异构的云基础设施在提升云计算环境安全性的同时会降低资源利用率。提出一种针对虚拟机轮换时的资源分配算法,将不同类型的资源抽象成维度不同的向量,并通过求解装箱问题实现资源分配中的负载平衡,同时为每个虚拟机设定驻留时间,对当前服务器的负载状态进行轮换以提升虚拟机的安全性。实验结果表明,资源动态分配算法在提高虚拟机安全性能的同时,能够减小轮换带来的负载波动。

关键词：云计算网络安全异构性轮换策略负载平衡

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达州红色印记数智资源库构建研究

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四川文理学院学报 2021年第1期31卷 28-31页

作者：梁弼倪思源姚先敏四川文理学院智能制造学院四川达州635000

达州是川陕革命老区核心区,这里有丰富的红色资源。随着现代社会的发展,这些红色资源已得到一定的开发和利用,但目前暂无一套完整的红色资源库。恰当使用数字媒体、大数据、数据挖掘、人工智能、云服务、互联网等技术来构建达州红色印... 详细信息

达州是川陕革命老区核心区,这里有丰富的红色资源。随着现代社会的发展,这些红色资源已得到一定的开发和利用,但目前暂无一套完整的红色资源库。恰当使用数字媒体、大数据、数据挖掘、人工智能、云服务、互联网等技术来构建达州红色印记数智资源库,这不但能实现达州红色资源数智化采集、存储和管理,而且能实现其数智化共享,最终实现达州红色资源数智化保护和传播,让红色印记薪火传承。

关键词：红色印记数智资源库采集子系统管理子系统共享子系统

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MViewer： mobile phone spatiotemporal data viewer

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Frontiers of Computer Science 2014年第2期8卷 298-315页

作者： Jiansu PU siyuan LIU Panpan XU Huamin QU Lionel M. ni Department of Computer Science Hong Kong University of Science and Technology Hong Kong 999077 China iLab Heinz College Carnegie Mellon University Pittsburgh PA 15601 USA

Nowadays movement patterns and people＇s be- havioral models are needed for traffic engineers and city plan- ners. These observations could be used to reason about mobil- ity and its sustainability and to support decision makers with reliable information. The very same knowledge about human diaspora and behavior extracted from these data is also valu- able to the urban planner, so as to localize new services, orga- nize logistics systems and to detect changes as they occur in the movement behavior. Moreover, it is interesting to inves- tigate movement in places like a shopping area or a working district either for commercial purposes or for improving the service quality. These kinds of tracking data are made avail- able by wireless and mobile communication technologies. It is now possible to record and collect a large amount of mobile phone calls in a city. Technologies for object tracking have recently become affordable and reliable and hence we were able to collect mobile phone data from a city in China from January 1, 2008 to December 31, 2008. The large amount of phone call records from mobile operators can be considered as life mates and sensors of persons to inform how many peo- ple are present in any given area and how many are entering or leaving. Each phone call record usually contains the caller and callee IDs, date and time, and the base station where the phone calls are made. As mobile phones are widely used in our daily life, many human behaviors can be revealed by an- alyzing mobile phone data. Through mobile phones, we can learn the information about locations, communications be- tween mobile phone users during their daily *** this work, we propose a comprehensive visual analysissystem named as MViewer, Mobile phone spatiotemporal data Viewer, which is the first system to visualize and analyze the population＇s mobility patterns from millions of phone call records. Our system consists of three major components： 1） visual analysis of user groups in

关键词： visual analysis mobility pattern mobile phone

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Strength-Toughening Model of Eutectic Ceramic Composite with Inherent Defects

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Chinese Journal of Mechanical Engineering 2014年第4期27卷 754-760页

作者： FU Yunwei ZHANG Long ni Xinhua LIU Xiequan CHEN Cheng ZHAO siyuan Department of Vehicle and Electric Engineering Ordnance Engineering College Department of Ground Artillery Wuhan Ordnance Non-commissioned Officers Academy

Strengthening and toughening mechanisms in composite ceramics is complex. A change in a single parameter induces multiple property variations. The multiple changes in properties are often incompletely represented in theoretical models. This incompleteness in the parameter chosen fails to explain the mechanism of failure in composite ceramics. The exponential toughness function is used to represent the pull-out toughening mechanism, which dominates the crack growth resistance curve（R-curve）. The strengthening-toughening model is established based on the Mori-Tanaka method（M-T method）. The influence of inherent defects on toughness function and strength is analyzed by using this model. The theoretical result is compared with the experiment data. This model exactly reflects the change in strength. The theoretical result indicates that defects change the toughness function. Moreover, micro-cracks increase toughness size ac, and the strength of crack instable extensions acutely decreases as defect content increases. This presented model establishes the relationship among the important mechanical parameters of defect, strength, elastic modulus, and the R-curve.

关键词： inherent defects pull-out toughening toughness function strength

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3D打印BIM模型在变电站三维可视化设计中的应用

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电力勘测设计 2022年第10期34卷 1-6,76页

作者：初建祥张彦彪罗金龙杨震郝小东郭帅倪思远内蒙古润蒙能源有限公司内蒙古呼和浩特010020 内蒙古电力勘测设计院有限责任公司内蒙古呼和浩特010020

传统的变电站施工阶段的总布置图为二维表达,对于空间布置复杂的工程和一些形状复杂的设备,二维图纸可读性差,难以表达变电站空间形态;用电脑查看BIM数字三维模型也存在一定的不足。为了实现直观可视化表达,在某变电站设计中采用3D打印... 详细信息

传统的变电站施工阶段的总布置图为二维表达,对于空间布置复杂的工程和一些形状复杂的设备,二维图纸可读性差,难以表达变电站空间形态;用电脑查看BIM数字三维模型也存在一定的不足。为了实现直观可视化表达,在某变电站设计中采用3D打印技术把变电站BIM数字三维模型打印成物理模型,交付业主用于现场施工指导和技术沟通,弥补了二维图纸表达方式的不足,为实现精细化施工和项目管理、提高建设效率和质量发挥了良好作用。

关键词： 3D打印 BIM模型变电站物理模型可视化设计

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Suppression of partially irreversible phase transition in O′3-Na_(3)ni_(2)SbO_(6)cathode for sodium-ion batteries by interlayered structural modulation

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Journal of Energy Chemistry 2022年第10期31卷 436-444,I0011页

作者： Jingjie Feng Jiajie Li ni Wen siyuan Chen Jian Wu Qinghua Fan Youzhong Dong Quan Kuang Yanming Zhao School of Physics South China University of TechnologyGuangzhou 510640GuangdongChina South China Institute of Collaborative Innovation South China University of TechnologyDongguan 523808GuangdongChina Guandong Provincial Key Laboratory of Advanced Energy Storage Materials South China University of TechnologyGuangzhou 510640GuangdongChina

As a promising cathode material for sodium ion batteries,honeycomb-ordered layered Na_(3)ni_(2)Sb O_(6)still suffers from rapid capacity fading because of partially irreversible phase ***,a substitution of Na+by Rb+with a larger ionic radius in honeycomb layered Na_(3)-xRbxni_(2)Sb O_(6)is proposed to modulate the interlayer *** results unveil that biphasic transition reversibility of the intermediate P′3phase is substantially enhanced,and the structure evolution behavior during the charge/discharge process changes due to the structural modulation,which contributes to a suppression of the unfavorable O_(1)phase and an alleviation of the lattice ***,Rb substituted samples exhibited an improved Na+(de)intercalation thermodynamics and *** to the modifications,the sample with optimized Rb content delivers superior cycle stability and rate capacity,demonstrating a feasible strategy for suppressing irreversible phase transition and developing high-performance honeycomb layered materials for sodium ion batteries.

关键词： Sodium-ion batteries High-voltage electrochemistry Honeycomb-ordered materials Rb doping Structural modulation

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Construction of hollow polydopamine nanoparticle based drug sustainable release system and its application in bone regeneration

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International Journal of Oral Science 2021年第3期13卷 282-291页

作者： Lu Wang Shuwei Liu Chunxia Ren siyuan Xiang Daowei Li Xinqing Hao Shilei ni Yixin Chen Kai Zhang Hongchen Sun Department of Oral Pathology Hospital of StomatologyJilin UniversityChangchunChina Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of StomatologyJilin UniversityChangchunChina State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchunChina

Nanomaterial-based drug sustainable release systems have been tentatively applied to bone ***,however,still face disadvantages of high toxicity,low biocompatibility,and low drug-load *** view of the low toxicity and high biocompatibility of polymer nanomaterials and the excellent load capacity of hollow nanomaterials with high specific surface area,we evaluated the hollow polydopamine nanoparticles(HPDA NPs),in order to find an optimal system to effectively deliver the osteogenic drugs to improve treatment of bone *** demonstrated that the HPDA NPs synthesized herein could efficiently load four types of osteogenic drugs and the drugs can effectively release from the HPDA NPs for a relatively longer time in vitro and in vivo with low toxicity and high *** of qRT-PCR,ALP,and alizarin red S staining showed that drugs released from the HPDA NPs could promote osteogenic differentiation and proliferation of rat bone marrow mesenchymal stem cells(rBMSCs)in *** data from micro-CT and H&E staining showed that all four osteogenic drugs released from the HPDA NPs effectively promoted bone regeneration in the defect of tooth extraction fossa in vivo,especially *** results suggest that the HPDA NPs,the biodegradable hollow polymer nanoparticles with high drug load rate and sustainable release ability,have good prospect to treat the bone defect in future clinical practice.

关键词： drugs dopamine release

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Tailoring structural properties of carbon via implanting optimal co nanoparticles in n-rich carbon cages toward high-efficiency oxygen electrocatalysis for rechargeable zn-air batteries

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Carbon Energy 2022年第4期4卷 576-585页

作者： Jie Yu Yawen Dai Zhenbao Zhang Tong Liu siyuan Zhao Chun Cheng Peng Tan Zongping Shao Meng ni Department of Building and Real Estate The Hong Kong Polytechnic UniversityKowloonHong KongChina Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefeiAnhuiChina State Key Laboratory of Materials-Oriented Chemical Engineering Department of Chemical EngineeringCollege of Chemical EngineeringNanjing Tech UniversityNanjingChina Department of Chemical Engineering Curtin UniversityPerthWestern AustraliaAustralia

Rational construction of carbon-based materials with high-efficiency bifunctionality and low cost as the substitute of precious metal catalyst shows a highly practical value for rechargeable Zn-air batteries(ZABs)yet it still remains ***,this study employs a simple mixing-calcination strategy to fabricate a high-performance bifunctional composite catalyst composed of N-doped graphitic carbon encapsulating Co nanoparticles(Co@NrC).Benefiting from the core-shell architectural and compositional advantages of favorable electronic configuration,more exposed active sites,sufficient electric conductivity,rich defects,and excellent charge transport,the optimal Co@NrC hybrid(Co@NrC-0.3)presents outstanding catalytic activity and stability toward oxygen-related electrochemical reactions(oxygen reduction and evolution reactions,i.e.,ORR and OER),with a low potential gap of 0.766 ***,the rechargeable liquid ZAB assembled with this hybrid electrocatalyst delivers a high peak power density of 168 mW cm^(−2),a small initial discharge-charge potential gap of 0.45 V at 10 mA cm^(−2),and a good rate ***,a relatively large power density of 108 mW cm^(−2) is also obtained with the Co@NrC-0.3-based flexible solid-state ZAB,which can well power LED *** work offers insights in developing excellent bifunctional electrocatalysts for both OER and ORR and highlights their potential applications in metal-air batteries and other energy-conversion/storage devices.

关键词： Co nanoparticles core-shell nanostructure N-doped graphitic carbon oxygen electrocatalysis Zn-air battery

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Extending MoS_(2)-based materials into the catalysis of non-acidic hydrogen evolution:challenges,progress,and perspectives

Materials Futures

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Materials Futures 2023年第2期2卷 54-78页

作者： Hao Fei Ruoqi Liu Yunze Zhang Hongsheng Wang Miao Wang siyuan Wang Meng ni Zhuangzhi Wu Jian Wang School of Materials Science and Engineering Central South UniversityChangsha 410083People’s Republic of China School of Energy and Environment City University of Hong KongKowloonHong Kong SARPeople’s Republic of China Department of Building and Real Estate Research Institute for Sustainable Urban Development(RISUD)&Research Institute for Smart Energy(RISE)The Hong Kong Polytechnic UniversityHong Kong SARPeople’s Republic of China

Water splitting is regarded as among the most prospective methods of generating green *** electrolytes of water electrolysis from acidic to non-acidic ones will enable the use of noble-metal-free electrocatalysts and mitigate material corrosion,thus lowering the capital cost of water electrolyzers and improving their operational ***,increasing electrolyte pH will degrade the hydrogen evolution reaction(HER)activity because of the reduced concentration of H_(3)O^(+)as reactants,making non-acidic HER *** accelerate HER,MoS_(2)-based materials with the advantages of unique atomistic structure,low cost,and high abundance have been considered prospective electrocatalysts to substitute for Pt in *** efforts are being spent on extending MoS_(2)-based materials into the catalysis of non-acidic HER,and their further development requires clarification of the existing challenges and current ***,it has not yet been discussed for non-acidic HER on MoS_(2)-based *** mitigate the disparity,we systematically overview MoS_(2)-based electrocatalysts for non-acidic HER,covering catalytic mechanisms,modulation strategies,materials development,current challenges,research progress,and *** review will contribute to the rational design of MoS_(2)-based materials for high-performance HER in non-acidic conditions.

关键词： MoS_(2) hydrogen evolution reaction non-acidic electrocatalyst

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