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Effects of a nurse-led heart failure clinic on hospital readmission and mortality in Hong Kong

Journal of Geriatric Cardiology 2016年第5期13卷 415-419页

作者： Ho Yu Cheng Sek Ying Chair Qun Wang Janet WH Sit Eliza ML Wong siu wai tang The Nethersole School of Nursing: Faculty of Medicine The Chinese University of Hong Kong Hong Kong China Cardiac Rehabilitation Centre Tung Wah Eastern Hospital Hong Kong China

Background Heart failure （HF） is a physically and socially debilitating disease that carries the burden of hospital re-admission and mortality. As an aging society, Hong Kong urgently needs to find ways to reduce the hospital readmission of HF patients. This study evaluates the effects of a nurse-led HF clinic on the hospital readmission and mortality rates among older HF patients in Hong Kong. Methods This study is a retrospective data analysis that compares HF patient in a nurse-led HF clinic in Hong Kong compared with HF patients who did not attend the clinic. The nurses of this clinic provide education on lifestyle modification and symptom monitoring, as well as titrate the medications and measure biochemical markers by following established protocols. This analysis used the socio-demographic and clinical data of HF patients who were aged 〉 65 years old and stayed in the clinic over a six-month period. Results The data of a total of 78 HF patients were included in this data analysis. The mean age of the patients was 77.38 ± 6.80 years. Approximately half of the HF patients were male （51.3%）, almost half were smokers （46.2%）, and the majority received 〈 six years of formal education. Most of the HF patients （87.2%） belonged to classes II and III of the New York Heart Association Functional Classification, with a mean ejection fraction of 47.15± 20.31 mL. The HF patients who attended the clinic （n = 38, 75.13 ± 5.89 years） were significantly younger than those who did not attend the clinic （n = 40, 79.53 ± 6.96 years）（P = 0.04）, and had lower recorded blood pressure. No other statistically significant difference existed between the socio-demographic and clinical characteristics of the two groups. The HF patients who did not attend the nurse-led HF clinic demonstrated a significantly higher risk of hospital readmission [odd ratio （OR）： 7.40; P 〈 0.01] than those who attended after adjusting for the effect of age and blood pressure. In addition, HF patients who att

关键词： Heart failure Hospital readmission Mortality Nurse-led clinic

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Ileocolonic mucormycosis in adult immunocompromised patients:A surgeon's perspective

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World Journal of Gastroenterology 2010年第9期16卷 1165-1170页

作者： Oswens siu-Hung Lo wai-Lun Law Division of Colorectal Surgery Department of SurgeryUniversity of Hong Kong Medical CentreQueen Mary Hospital

We report three cases of ileocolic mucormycosis in adult immunocompromised patients presenting as acute *** patients underwent laparotomy but two of them died from multiorgan failure before the diagnoses were *** diagnosis of gastrointestinal mucormycosis is rarely suspected,and antemortem diagnosis is made in only 25%-50% of *** cases illustrate the difficulty encountered by surgeons in managing acute abdomen in neutropenic patients with hematological *** management of colonic mucormycosis in the published literature is also reviewed.

关键词： Gastrointestinal mucormycosis Colon Immunocompromised Surgery

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Therapeutic implications of antioxidant defense in acute pancreatitis

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Hepatobiliary & Pancreatic Diseases International 2014年第4期13卷 346-347页

作者： Zhao-Xiang Bian siu-wai Tsang Clinical Division School of Chinese Medicine HongKong Baptist University

Acute pancreatitis is an inflammation initially localized in the pancreas,which may be accompanied with severe complications such as multi-organ failure,gastrointestinal hemorrhage and *** in ten severe cases of acute pancreatitis develops systemic inflammatory response *** treatment,acute pancreatitis can be a life-threatening disease as its mortality rate amounts to 5%-10%in general,and up to 35%in cases of severe course.[1]Over the years,the role of oxidative stress

关键词： initially defense pancreas malnutrition inflammation accompanied mortality threatening oxidative antioxidant

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Rare complication of inflammatory bowel disease-like colitis from glycogen storage disease type 1b and its surgical management:A case report

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World Journal of Clinical Cases 2021年第16期9卷 4081-4089页

作者： Frederick Chi-wai Lui Oswens siu-Hung Lo Department of Surgery LKS Faculty of MedicineThe University of Hong KongHong KongChina

BACKGROUND Glycogen storage disease(GSD)is an autosomal recessive inborn metabolic *** with GSD are prone to hypoglycaemia,hyperlactacidemia and *** type 1b(GSD-1b)patients specifically can develop neutropenia,recurrent bacterial infection and inflammatory bowel disease(IBD).Documentation of the long-term outcomes of surgical management of GSD-1b has been scarce,especially for Asian *** herein describe a case of GSD-1b complicated by IBD-like colitis and coloduodenal *** patient was managed successfully with surgical *** SUMMARY A 20-year-old Chinese lady confirmed by genetic testing to have GSD-1b was initially managed with uncooked cornstarch and granulocyte-colony stimulating *** recurrent abdominal symptoms,her condition was treated as clinical“Crohn’s disease”with mesalazine,prednisolone and azathioprine *** showed a tight stricture at the hepatic *** computerized tomographic colonography revealed a phlegmon at the ileocaecal region with a suspected coloduodenal *** an exploratory laparotomy was performed and severe colitis at the ascending colon with coloduodenal fistula was *** hemicolectomy with primary anastomosis and repair of the duodenum were *** management of complications from GSD-1b associated IBD-like colitis has rarely been ***-line treatment would usually be *** intervention like hemicolectomy is mainly reserved for refractory *** Surgical management of coloduodenal fistula in GSD-1b patients is a feasible and safe option when failed conservative management.

关键词： Glycogen storage disease Coloduodenal fistula Inflammatory bowel diseaselike colitis Case report Perioperative management

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An LDPC coded cooperative MIMO scheme over Rayleigh fading channels with unknown channel state information

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Journal of Zhejiang University-Science C(Computers and Electronics) 2013年第1期14卷 30-41页

作者： Shun-wai ZHANG Feng-fan YANG Lei tang College of Electronic and Information Engineering Nanjing University of Aeronautics and Astronautics

This paper describes a coded cooperative multiple-input multiple-output(MIMO) scheme,where structured low-density parity-check(LDPC) codes belonging to a family of repeat-accumulate(RA) codes are *** outage probability of the scheme over Rayleigh fading channels is *** an unknown channel state information(CSI) scenario,adaptive transversal filters based on a spatio-temporal recursive least squares(ST-RLS) algorithm are adopted in the destination to realize receive diversity ***,a joint 'Min-Sum' iterative decoding is effectively carried out in the *** a decoding algorithm agrees with the bilayer Tanner graph that can be used to fully characterize two distinct structured LDPC codes employed by the source and *** results verify the effectiveness of the adopted filter in the coded cooperative MIMO *** analysis and numerical simulations show that the LDPC coded cooperative MIMO scheme can well combine cooperation diversity,multi-receive diversity,and channel coding gains,and clearly outperforms coded noncooperation schemes under the same conditions.

关键词： Cooperative multiple-input multiple-output (MIMO) Repeat-accumulate (RA) codes Bilayer Tanner graph Spatio-temporal recursive least squares (SToRLS) algorithm Joint 'Min-Sum' iterative decoding

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Low-temperature conformal vacuum deposition of OLED devices using close-space sublimation

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Journal of Semiconductors 2023年第9期44卷 62-67页

作者： Bryan siu Ting Tam Shou-Cheng Dong Ching W.tang State Key Laboratory of Advanced Displays and Optoelectronics Technologies Department of Electronic and Computer EngineeringThe Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Institute for Advanced Study The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

Close-space sublimation(CSS)has been demonstrated as an alternative vacuum deposition technique for fabricating organic light-emitting diodes(OLEDs).CSS utilizes a planar donor plate pre-coated with organic thin films as an area source to rapidly transfer the donor film to a device substrate at temperatures below 200℃.CSS is also conformal and capable of depositing on odd-shaped substrates using flexible donor *** evaporation behaviors of organic donor films under CSS were fully characterized using model OLED materials and CSS-deposited films exhibited comparable device performances in an OLED stack to films deposited by conventional point *** low temperature and conformal nature of CSS,along with its high material utilization and short process time,make it a promising method for fabricating flexible OLED displays.

关键词： close-space sublimation OLED thin film low temperature vacuum deposition

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Derivations on the Algebra of Operators in Hilbert C~*-Modules

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Acta Mathematica Sinica,English Series 2012年第8期28卷 1615-1622页

作者： Peng Tong LI De Guang HAN wai Shing tang Department of Mathematics Nanjing University of Aeronautics and Astronautics Department of Mathematics University of Central Florida Department of Mathematics National University of Singapore

Let M be a full Hilbert C＊-module over a C＊-algebra A, and let End^（.A4） be the algebra of adjointable operators on M. We show that if A is unital and commutative, then every derivation of End＊A（M） is an inner derivation, and that if A is a-unital and commutative, then innerness of derivations on ＂compact＂ operators completely decides innerness of derivations on EndA（M）. If .4 is unital （no commutativity is assumed） such that every derivation of A is inner, then it is proved that every derivation of EndA（Ln（A）） is also inner, where Ln（A） denotes the direct sum of n copies of A. In addition, in case A is unital, commutative and there exist xo,yo ∈M such that 〈xo,yo〉 = 1, we characterize the linear A-module homomorphisms on EndA（M） which behave like derivations when acting on zero products.

关键词： Derivations inner derivations C*-algebras Hilbert C*-modules

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Clinicopathological survey of 23 patients with lacrimal fossa lesions in Hong Kong

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International Journal of Ophthalmology(English edition) 2011年第3期4卷 311-313页

作者： Danny siu-Chun Ng Edwin Chan Kin Yau Clement wai-Nang Chan Department of Ophthalmology Tung Wah Eastern Hospital

AIM: To survey the clinicopathological correlations of lacrimal fossa lesions in the Hong Kong population. METHODS: A total of 23 patients with lacrimal fossa lesions were identified radiologically. The mean age at the time of diagnosis was 52 year-old. The medical records of patients diagnosed with lacrimal fossa lesions and subsequently underwent radiological investigations were collected and reviewed retrospectively throughout a six years period from 2000 to 2006 from three regional hospitals (Tung Wah Eastern Hospital, Pamela Youde Nethersole Eastern Hospital and Queen Mary Hospital) belonging to the Hong Kong Mega Cluster. Patient demographics, presenting signs and symptoms, imaging modalities, pathological reports and subsequent management were recorded. RESULTS: The most common initial presenting symptom was upper lid swelling (83%) followed by proptosis (13%). 19 patients (83%) had benign lacrimal fossa lesion and 4 patients (17%) had malignancy. Three of the malignancies were lymphomas and one was adenoid cystic carcinoma. CONCLUSION: Age is an important factor in considering the differential diagnosis of lacrimal fossa lesion. Lymphoproliferative diseases have the highest incidence in patients over 60 years of age while inflammatory lesions are more common in younger patients in Hong Kong.

关键词： lacrimal gland tumor lymphoma

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Engineering advanced dynamic biomaterials to optimize adoptive T-cell immunotherapy

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Engineered Regeneration 2021年第1期2卷 70-81页

作者： wai Ki Wong Bohan Yin Anel Rakhmatullina Jingying Zhou siu Hong Dexter Wong Department of Bioengineering Imperial College LondonLondon SW72AZUnited Kingdom Department of Biomedical Engineering The Hong Kong Polytechnic UniversityKowloonHong KongChina School of Biomedical Sciences The Chinese University of Hong KongShatinHong KongChina

Adoptive T-cell therapy(ACT)is a promising therapeutic approach based on the concept of potent T-cell mediated immunity against the *** outcome of antigen-specific T-cells responses relies on the interaction between T-cells and antigen-presenting cells,which provides signals for generating different T-cell phenotypes with different roles in tumor ***,such interaction is often not optimal in vivo and results in low therapeutic *** reach the full potential of the T-cell response,current research put effort into developing dynamic biomaterials as artificial antigen-presenting cells to study and regulate the T-cell activity for controlling T-cell *** this perspective,we provide(1)an overview of ACT and general T-cells behaviors,(2)explore the insight on how biomaterials can be used for studying and regulating T-cell behaviors,(3)and discuss conceptual gaps in knowledge for biomaterials-based immunotherapy.

关键词： T-cell mechanobiology Dynamic nanobiomaterials Adoptive T-cell immunotherapy T-Ligand presentation

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Bevacizumab for neovascular age-related macular degeneration in Chinese patients in a clinical setting

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International Journal of Ophthalmology(English edition) 2016年第3期9卷 424-430页

作者： Danny siu-Chun Ng Alvin Kwan-Ho Kwok Justin Man-Kit Tong Clement wai-Nang Chan Walton wai-Tat Li Department of Ophthalmology & Visual Sciences the Chinese University of Hong Kong Department of Ophthalmology Hong Kong Sanatorium and Hospital Department of Ophthalmology United Christian Hospital

AIM：To determine the outcome of non-investigational treatment with intravitreal bevacizumab（IVB） in neovascular age-related macular degeneration（AMD）patients.· METHODS：Retrospective chart review of 81 eyes with neovascular AMD followed-up for at least 12 mo and received 3-monthly loading IVB ***-treat was based upon the individual clinician＇s *** visual acuity（BCVA） and optical coherence tomography measurements of central foveal thickness outcomes were evaluated at 12,24 mo.· RESULTS：Eighty-one eyes（of 75 patients） completed12 mo of follow-up and 44 eyes（of 41 patients） completed24 mo of *** mean baseline logMAR BCVA significantly improved from 0.94±0.69 to 0.85±0.68 at12mo（P〈0.001） and from 0.91±0.65 to 0.85±0.60（P=0.004）at 24 *** proportion of eyes that lost 〈15 logMAR letters at 12 mo was 90.1%and at 24 mo was 81.8%.IVB was effective in improving visual acuity in both treatment naive and previous photodynamic therapy（PDT）-treated *** naive patients required significantly fewer injections than patients with prior *** regression analysis identified that poorer baseline visual acuity was associated with greater improvement in visual acuity（P=0.015）.· CONCLUSION：Fewer injections in clinical practice may result in suboptimal visual outcomes compared with clinical trials of IVB in neovascular AMD *** baseline visual acuity and prior PDT treatment may also improve vision after *** safety and durability of effect was maintained at 24 mo.

关键词： bcvacizumab age-related maculardegeneration Chinese

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