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Dietary supplementation of dried plum:a novel strategy to mitigate heat stress in broiler chickens

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Journal of Animal Science and Biotechnology 2021年第3期12卷 1056-1072页

作者： Sanjeev Wasti nirvay Sah Amit K.singh Chin n.Lee Rajesh Jha Birendra Mishra Department of Human nutrition Food and Animal Sciences University of Hawaii at ManoaHonoluluHI 96822USA

Background:Heat stress is a significant problem in the poultry industry,causing a severe economic loss due to its detrimental effects on chickens’health and *** plum(DP)is a good source of minerals,vitamins,antioxidants,and phenolic *** have suggested that DP has several health benefits,such as maintaining the body’s redox system,immune status,and calcium *** on the health benefits of DP,we hypothesized that the dietary supplementation of DP would alleviate the detrimental effects of heat stress on broiler ***:to test the hypothesis,day-old broiler chicks(n=72)were randomly allocated to three treatment groups(n=24/group):no heat stress(nHS),heat stress(HS),and heat stress with dried plum(HS+DP),and reared under st.n.ard *** inclusion of 2.5%DP in the feed of the HS+DP group was made during the treatment period,while birds in other groups were provided with a st.n.ard finisher *** 21 days,birds in the HS and HS+DP groups were exposed to cyclic heat stress conditions(33℃ for 8 h during daytime)for 3 weeks,while those in the nHS group were reared under normal conditions(22-24℃).Weekly body weight and feed intake were recorded to calculate the average daily gain(ADG),average daily feed intake(ADFI),and feed conversion ratio(FCR).Heat stress significantly decreased the final body weight,ADG,ADFI,and increased FCR compared to the nHS group,whereas dietary supplementation of DP significantly improved these growth performance parameters compared to the HS ***,supplementation of DP significantly increased the expression of heat shock protein-related genes(HSF1,HSF3,HSP70,and HSP90),antioxidant-related genes(SOD1,SOD2,GPX1,GPX3,PRDX1,and t.n.,tight junction-related genes(CLDn1,and OCLn),and immune-related genes(IL4,MUC2)in the ileum as compared to the HS *** microbiota analysis showed significant enrichment of Bacillales,Christ.n.enellaceae,Bacillaceae,Peptostreptococcaceae,and Anaerot

关键词： Dried plum Gene expression Heat stress Microbiota Mitigation

Impact of post harvest treatment on antioxidant activity and phenolic profile of Moringa oleifera lam leaves

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Food Production, Processing and nutrition 2021年第1期3卷 296-311页

作者： Edith n.Fombang Pierre nobossé Carl M.F.Mbofung Damanpreet singh Department of Food Science and nutrition National School of Agro-Industrial SciencesENSAIUniversity of NgaoundereP.O.Box 455NgaoundereAdamawa RegionCameroon Pharmacology and toxicology Laboratory CSIR-Institute of Himalayan Bioresource TechnologyPalampurHimachal Pradesh 176061India

Moringa oleifera leaves are an import.n. source of dietary phytochemicals,such as flavonoids with high antioxidant activity(AOA).these components are however influenced by the post-harvest treatments applied as well as the processing ***,it is crucial to determine the most appropriate post-harvest treatment that preserves or enhances *** this effect the influence of steam blanching,fermentation/oxidation,oven drying and roast.n. of fresh Moringa leaves on their AOA was *** conditions of time and temperature for each treatment were optimised using response surface *** effect of the different treatments at optimal conditions on phenolic profile and AOA were *** achieved the most significant(pnt in phenolics(43%)and AOA(22–31%),which was accompanied by the formation of 2 new compounds,quercet.n.3-O-acetylglucoside and *** blanching had the most deleterious effect on phenolics(-31%)and ***-harvest treatments qualitatively and quantitatively affect phytochemical profile of Moringa leaves.

关键词： Moringa oleifera leaves Post harvest treatment Optimisation(response surface methodology) Phenolic profile Antioxidant activity

Comparative study of leaching of silver nanoparticles from fabric and effective effluent treatment

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Journal of Environmental Sciences 2012年第5期24卷 852-859页

作者： Aneesh Pasricha Sant Lal Jangra nahar singh neeraj Dilbaghi K. n. Sood Kanupriya Arora Renu Pasricha Delhi Public School Dwarka New Delh-110078i India Department of Bio & nano technology Guru Jambheshwar University of Science & Technology Hisar Haryana-125001 India CSIR-national Physical Laboratory

nano silver （Agn） is employed as an active antimicrobial agent, but the environmental impact of Agn released from commercial products is unknown. the quantity of nanomaterial released from consumer products during use should be determined to assess the environmental risks of advancement of nanotechnology. this work investigated the amount of silver released from three different types of fabric into water during washing. three different types of fabric were loaded with chemically synthesized Ag nanoparticles and washed repeatedly under simulated washing conditions. Variable leaching rates among fabric types suggest that the manufacturing process may control the release of silver reaching the waste water treatment plants. In an attempt to recover the Agn for reutilization and to save it from pollut.n. water, the effluents from the wash were efficiently treated with bacterial strains. this treatment was based on biosorption and was very efficient for the elimination of silver nanoparticles in the wash water. the process ensured the recovery of the Agn leached into the effluent for reutilization, thus prevent.n. environmental repercussions.

关键词： silver nanoparticles leaching eco-environment effluent SEM tEM AAS

Genetic improvement of wheat grain quality at CIMMYt

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Frontiers of Agricultural Science and Engineering 2019年第3期6卷 265-272页

作者： Carlos GUZMán Karim AMMAR Velu GOVInDAn Ravi singh Global Wheat Program The International Maize and Wheat Improvement Center (CIMMYT)

the International Maize and Wheat Improvement Center(CIMMYt) is the global leader in publiclyfunded maize and wheat research and in farming systems based on these *** leads the Global Wheat Program(GWP), which includes some of the largest wheat breeding programs in the *** GWP has been successful in developing wheat germplasm that is used ext.n.ively *** quality improvement is a central component of all the breeding efforts at CIMMYt and the Wheat Chemistry and Quality Laboratory represents an integral part of the breeding *** quality is addressed at CIMMYt over the full range of this very wide and variable concept with milling,processing, end-use and nutritional quality *** progenitors and advanced lines developed by the breeders are assessed for diverse quality attributes, with the aim of identifying those that fulfill the requirements in terms of milling, processing, end-use and nutritional quality in different target *** research is conducted to make more efficient the integration of wheat quality traits in the breeding *** main topics being addressed are(1) methodologies to analyze grain quality traits,(2) genetic control and environmental effects on quality traits,(3) characterization of genetic resources for quality improvement, and(4) diversifying grain properties for novel uses.

关键词： biofortification breeding grain quality wheat

COVID-19 Related Organ Damage

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Advances in Infectious Diseases 2022年第4期12卷 813-823页

作者： Rohit Mittal Harmel singh Chahal Gurpreet singh Sandhu University College of Pharmacy Guru Kashi University Talwandi Sabo India Government Polytechnic College for Girls Patiala India Khalsa College of Pharmacy Amritsar India

Coronavirus particles contain four main structural proteins. these are the spike (S), membrane (M), envelope (E), and nucleocapsid (n) proteins, all of which are encoded within the 3’ end of the viral genome. the S protein (~150 kDa) utilizes an n-terminal signal sequence to gain access to the ER, and is heavily n-linked glycosylated. In view of the increase in death due to COVID-19 (coronavirus disease), it is import.n. to investigate the pot.n.ial effects the coronavirus on different organs. A literature search was performed from Elsevier, Pubmed, Springer, and Hindawi, and literature is reviewed using customized search strategies. the search strategy included the following terms Cardiovascular effect, neurological effect, and kidney. Myocardial damage is a common occurrence in patients with COVID-19 disease hospitalisation. this is characterized by a rise in troponin. Vascular endothelial damage in both small and mid-sized pulmonary vessels was noted together with Disseminated intravascular coagulation (DIC), Deep vein thrombosis (DVt), and Pulmonary embolism (PE), result.n. in pulmonary infarction. Liver damage in patients with coronavirus infections might be directly caused by the viral infection of liver cells. neuronal pathway is an import.n. vehicle for neurotropic viruses to enter the CnS (Central nervous system). Recent research studies show that apoptosis is implicated in a variety of ocular disorders, including glaucoma, ret.n.tis pigmentosa, cataract development, ret.n.blastoma, ret.n.l ischemia, diabetic ret.n.pathy, and ocular murine glaucoma. the more the underst.n.ing about this new virus and its occurrence, the better the ability of people to cope with it. It’s far hoped that we will conquer COVID-19 soon with the invention of powerful vaccines, pills, and remedies.

关键词： Myocardial Damage Corona Virus Liver Kidney

Low-cost high entropy alloy(HEA)for high-efficiency oxygen evolution reaction(OER)

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nano Research 2022年第6期15卷 4799-4806页

作者： Lalita Sharma nirmal Kumar Katiyar Arko Parui Rakesh Das Ritesh Kumar Chandra Sekhar tiwary Abhisek K.singh Aditi Halder Krishanu Biswas School of Basic Sciences Advanced Materials Research Centre(AMRC)Indian Institute of Technology Mandi(H.P)KamandMandi 175005India Department of Materials Science and Engineering Indian Institute of Technology KanpurKanpur 208016India School of Engineering London South Bank UniversityLondonSE10 AAUK Materials Research Centre Indian Institute of ScienceBangalore 560012India Metallurgical and Materials Engineering Indian Institute of Technology KharagpurKharagpur 382355India

Oxygen evolution reaction(OER)is the key step involved both in water splitt.n. devices and rechargeable metal-air batteries,and hence,there is an urgent.n.ed for a stable and low-cost material for efficient *** the present investigation,Co-Fe-Ga-niZn(CFGnZ)high entropy alloy(HEA)has been utilized as a low-cost electrocatalyst for ***,after cyclic voltammetry activation,CFGnZ-nanoparticles(nPs)are covered with oxidized surface and form high entropy(oxy)hydroxides(HEOs),exhibit.n. a low overpot.n.ial of 370 mV to achieve a current density of 10 mA/cm^(2)with a small tafel slope of 71 mV/*** alloy has higher electrochemical stability in comparison to state-of-the art RuO2 electrocatalyst as no degradation has been observed up to 10 h of *** electron microscopy(tEM)studies after 10 h of long-term chronoamperometry test showed no change in the crystal structure,which confirmed the high stability of *** density functional theory(DFt)based calculations show that the closeness of d(p)-band centers to the Fermi level(EF)plays a major role in determining active *** work highlights the tremendous pot.n.ial of CFGnZ HEA for OER,which is the primary reaction involved in water splitt.n..

关键词： high entropy alloy cyclic voltammetry activation oxygen evolution reaction electrocatalyst nanocrystalline catalyst

Diperoxo Complexes of Vanadium（V） Containing Mannich Base Ligands

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Chinese Journal of Chemistry 2011年第1期29卷 53-58页

作者： Mahajan, Simpy singh, Balgar Sharma, Mohita Sheikh, H. n. Kalsotra, B. L. Department of Chemistry University of Jammu Jammu 180006 India

the vanadium（V） peroxo complexes containing Mannich base ligands having composition na[VO（O2）2（L-L）]·H2O [where L-L=morpholinobenzyl acetamide （MBA）, piperidinobenzyl acetamide （PBA）, morpholinobenzyl benzamide （MBB）, piperidinobenzyl benzamide （PBB）, morpholinomethyl benzamide （MMB）, piperidinomethyl benzamide （PMB）, morpholinobenzyl formamide （MBF）, piperdinobenzyl formamide （PBF）] have been reported. the complexes have been prepared by stirring vanadium pentoxide with excess of 30% aque- ous-H202 followed by treatment with ethanolic solution of the ligand and finally maintained the pH of the reaction mixture by adding dilute solution of sodium hydroxide. the synthesized complexes have been characterized by various physico-chemical techniques, via elemental analysis, molar conductivity, magnetic susceptibility measure- ments, infra red, electronic, mass, ~H nMR spectral and tGA/DtA studies. these studies revealed that the synthesized complexes are uni-univalent electrolytes and diamagnetic in nature. the ligands are bound to metal in a bi- dentate mode through carbonyl oxygen and the ring nitrogen. thermal analysis result provides conclusive evidence for the presence of one molecule of lattice water in the complexes. Mass spectra confirm the molecular mass of the complexes.

关键词： peroxo complex Mannich base lattice water isotopic abundance mass spectrometry n oligands

Investigat.n. the effects of Pentoxifylline on human breast cancer cells using Raman spectroscopy

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Journal of Innovative Optical Health Sciences 2015年第2期8卷 26-36页

作者： Peeyush n.Goel S.P.singh C.Murali Krishna R.P.Gude Gude Lab ACTRECTata Memorial Center KhargharNavi Mumbai 410210 India Chilakapati Lab ACTRECTata Memorial Center KhargharNavi Mumbai 410210 India

Breast cancer is one of the leading causes of cancer-related deaths in a global *** the present study,biochemical changes exerted upon Pentoxifylline(PtX)treatment had been ap-praised in human breast cancer cells using Raman *** are no clinically approved methods to monitor such therapeutic responses *** spectral profiling is suggestive of changes in DnA,protein and lipid cont.n.s showing a linear relationship with drug ***,multivariate analysis using principal component based linear-discriminant-analysis(PC-LDA)was employed for dlassifying the control and the PtX treated *** findings support the feasibility of Raman spectroscopy as an alternate/adjunct label-free,objective method for monitoring drug-induced modifications against breast cancer cells.

关键词： Pentoifylline MDA-MB-231 breast cancer cells Raman spectroscopy spectra multivariate analysis

Drop formation at.n.zzles submerged in quiescent cont.n.ous phase： an experimental study with tBP-dodecane and nitric acid system

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nuclear Science and techniques 2018年第6期29卷 110-118页

作者： Amitava Roy MayurDarekar K. K. singh K. t. Shenoy R. B. Grover Homi Bhabha national Institute Anushaktinagar Mumbai 400094 India Chemical Engineering Division Bhabha Atomic Research Centre Mumbai 400085 India

Solvent extraction is an import.n. process in the nuclear fuel cycle. tributyl phosphate(tBP) diluted with dodecane is commonly used as a solvent for extract.n. heavy metals from nitric acid medium. Studies on hydrodynamics of a single drop, which is the smallest mass transfer entity, are required for better underst.n.ing of the complex mass transfer and phase separation phenomena that occur in extraction equipment. In this study, drop formation at.n.zzles is studied using 30% tBP-dodecane as the dispersed phase and dilute nitric acid as the quiescent cont.n.ous phase. Experiments are carried out to determine the drop diameter, jett.n. velocity, drop detachment height and drop detachment time for various dispersed phase velocities, nozzle diameters(1.91, 3.04, and 4.88 mm), and nitric acid concentrations(0.01, 1, 3 n). Drop formation is captured using high-speed imaging, which enables quantification of drop size, onset of jett.n., drop detachment height, and drop detachment time. Experimental data are used to propose correlations for predict.n. drop diameter and minimum jett.n. velocity. the correlations are found to be very accurate with average absolute relative errors being 5.23 and 2.97%, respectively.

关键词：试验性硝酸静止沉没系统高速度分离现象磷酸盐