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亚洲的核不扩散和安全保障:印度对国际和本地区的事态发展,NPT...

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国际原子能机构通报 1992年第1期34卷 41-44页

作者： singh,sk

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大型超导发电机的今后发展概况

船电技术 1990年第2期10卷 42-46页

作者： singh,sk 耿树彬

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印度甘蔗化学除草

国外农学（甘蔗） 1989年第2期 15-18页

作者： singh,sk 郑世庆

多西他赛纳米囊的体外细胞毒性和细胞摄取考察

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中国医药工业杂志 2015年第3期46卷 276-276页

作者： singh sk

采用聚电解质层层自组装技术制备了高载药量的载多西他赛纳米囊（DTX-NCs），并考察其外观、粒度分布、C电位、包封率和体外释放情况。透射电镜观察结果表明，颗粒表面围绕着聚电解质包衣层。所得制品粒径在亚微米范围内，在每步包衣后... 详细信息

采用聚电解质层层自组装技术制备了高载药量的载多西他赛纳米囊（DTX-NCs），并考察其外观、粒度分布、C电位、包封率和体外释放情况。透射电镜观察结果表明，颗粒表面围绕着聚电解质包衣层。所得制品粒径在亚微米范围内，在每步包衣后测得的ζ电位在（＋34．64±1．5）mV和（-33．25±2．1）mV之间轮换。本品无潜在的溶血性风险，提示可用于静脉给药。

关键词：多西他赛体外细胞毒性纳米囊细胞摄取透射电镜观察聚电解质自组装技术粒度分布

Morphotaxonomic and phylogenetic analysis of Saprolegnia ferax from India

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Studies in Fungi 2018年第1期3卷 49-58页

作者： singh PN singh sk Lagashetti AC Ackah FK National Fungal Culture Collection of India Biodiversity and Palaeobiology GroupMACS’Agharkar Research InstituteGG Agarkar RoadPune 411004India Department of Crop Science School of AgricultureCollege of Agriculture and Natural SciencesUniversity of Cape CoastGhana

Saprolegnia ferax is isolated from polluted water sample collected from Mula River,Pune,Maharashtra,*** isolated taxon is illustrated and compared with the morphotaxonomy based first record of Indian *** isolated by Wani et al.(2017).The present study deals with the re-description of the isolated taxon *** based on detail morphological features,sequence analysis and phylogeny of ITS and LSU regions of rDNA.

关键词： ITS and LSU rDNA Morphotaxonomy Oomycete Saprolegnia

A Novel High-Efficiency Transaction Verification Scheme for Blockchain Systems

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1613-1633页

作者： Jingyu Zhang Pian Zhou Jin Wang Osama Alfarraj Saurabh singh Min Zhu School of Computer&Communication Engineering Changsha University of Science&TechnologyChangsha410015China Science and Technology on Information Systems Engineering Laboratory School of Systems EngineeringNational University of Defense TechnologyChangsha410073China Computer Science Department King Saud UniversityRiyadh11437Saudi Arabia Department of Artificial Intelligence and Big Data Woosong UniversityDaejeon34606South Korea College of Information Science and Technology Zhejiang Shuren UniversityHangzhou310015China

Blockchain can realize the reliable storage of a large amount of data that is chronologically related and verifiable within the *** technology has been widely used and has developed rapidly in big data systems across various *** increasing number of users are participating in application systems that use blockchain as their underlying *** the number of transactions and the capital involved in blockchain grow,ensuring information security becomes *** the verification of transactional information security and privacy has emerged as a critical ***-based verification methods can effectively eliminate the need for centralized third-party ***,the efficiency of nodes in storing and verifying blockchain data faces unprecedented *** address this issue,this paper introduces an efficient verification scheme for transaction ***,it presents a node evaluation module to estimate the activity level of user nodes participating in transactions,accompanied by a probabilistic analysis for all ***,this paper optimizes the conventional transaction organization form,introduces a heterogeneous Merkle tree storage structure,and designs algorithms for constructing these heterogeneous *** analyses and simulation experiments conclusively demonstrate the superior performance of this *** verifying the same number of transactions,the heterogeneous Merkle tree transmits less data and is more efficient than traditional *** findings indicate that the heterogeneous Merkle tree structure is suitable for various blockchain applications,including the Internet of *** scheme can markedly enhance the efficiency of information verification and bolster the security of distributed systems.

关键词： Blockchain architecture transaction verification information security heterogeneous Merkle tree distributed systems

Emergence of taurine as a therapeutic agent for neurological disorders

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Neural Regeneration Research 2024年第1期19卷 62-68页

作者： Ashok Jangra Priyanka Gola Jiten singh Pooja Gond Swarnabha Ghosh Mahesh Rachamalla Abhijit Dey Danish Iqbal Mehnaz Kamal Punya Sachdeva Saurabh Kumar Jha Shreesh Ojha Dinesh Kumar Niraj Kumar Jha Hitesh Chopra Shing Cheng Tan Department of Pharmaceutical Sciences Central University of HaryanaMahendergarhHaryanaIndia Department of Biology University of SaskatchewanSaskatoonSKCanada Department of Life Sciences Presidency UniversityKolkataWest BengalIndia Department of Health Information Management College of Applied Medical SciencesBuraydah Private CollegesBuraydahSaudi Arabia Department of Pharmaceutical Chemistry College of PharmacyPrince Sattam Bin Abdulaziz UniversityAl-KharjSaudi Arabia GloNeuro Vishwakarma RoadNoidaIndia Department of Biotechnology School of Engineering&Technology(SET)Sharda UniversityGreater NoidaUttar PradeshIndia Department of Pharmacology and Therapeutics College of Medicine and Health SciencesUnited Arab Emirates UniversityAl AinUnited Arab Emirates School of Bioengineering&Biosciences Lovely Professional UniversityPhagwaraIndia Department of Biotechnology School of Applied&Life Sciences(SALS)Uttaranchal UniversityDehradunIndia Chitkara College of Pharmacy Chitkara UniversityPunjabIndia UKM Medical Molecular Biology Institute Universiti Kebangsaan MalaysiaKuala LumpurMalaysia

Taurine is a sulfur-containing,semi-essential amino acid that occurs naturally in the *** alternates between inflammation and oxidative stress-mediated injury in various disease *** part of its limiting functions,taurine also modulates endoplasmic reticulum stress,Ca^(2+)homeostasis,and neuronal activity at the molecular *** effectively protects against a number of neurological disorders,including stro ke,epilepsy,cerebral ischemia,memory dysfunction,and spinal cord *** various therapies are available,effective management of these disorders remains a global *** 30 million people are affected *** design of taurine fo rmation co uld lead to potential drugs/supplements for the health maintenance and treatment of central nervous system *** general neuroprotective effects of taurine and the various possible underlying mechanisms are discussed in this *** article is a good resource for understanding the general effects of taurine on various *** the strong evidence for the neuropharmacological efficacy of taurine in various experimental paradigms,it is concluded that this molecule should be considered and further investigated as a potential candidate for neurotherapeutics,with emphasis on mechanism and clinical studies to determine efficacy.

关键词： antioxidant epilepsy γ-amino butyric acid neurodegenerative disorders neuroprotection oxidative stress spinal cord injury taurine

Synthesis and evaluation of novel analogues of mangiferin as potent antipyretic

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Asian Pacific Journal of Tropical Medicine 2011年第11期4卷 866-869页

作者： Shashi Kant singh Saurabh K Sinha sk Prasad R Kumar Bhawani S Bithu S Sadish Kumar P singh Varanasi College of Pharmacy Uttar PradeshVaranasiIndia Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasiUttar PradeshIndia Institute of Technology and Sciences Paramedical College(Pharmacy)MuradnagarUttar PradeshIndia Uday Pratap College VaranasiUttar PradeshIndia

Objective:To screen different analogues of mangiferin pharmacologically for antipyretic activity. Methods:The naturally occurring xanthone glycoside mangiferin was isolated by column chromatography from the elhanolic extract of stem bark of Mangifera *** was further converted to 5-(N-phenylamino methyleno) mangiferin.5-(N-p-chlorophenylamino methyleno) mangiferin,5-(N-2-methyl phenylamino methyleno) mangiferin.5-(N-p-methoxy phenylamino methyleno) mangiferin.5-(N,N-diphenylamino methyleno) mangiferin,5-(N-α-napthylamino methyleno) mangiferin and 5-(N-4-methyl phenylamino methyleno) mangiferin *** synthesized compounds were further screened for antipyretic activity along with mangiferin at a dose level of 100 and 200 tng/*** and its analogues were characterized by melting point and R_f value determination and through spectral technique like UV,IR,and NMR spectral ***:The antipyretic activity of mangiferin as well as all analogues was found to be more significant in at higher dose ie.200 mg/kg which was depicted thmugh a decrease in rectal temperature up to 3 ***:The antipyretic activity of mangiferin and its analogues may be attributed to inhibition in synthesis of TNF-αand anti-oxidant activity associated with amelioration of inflammatory actions of cytokines.

关键词： Mangifera indica Mangiferin Antipyretic

Isolated tuberculous splenic abscess in an immunocompetent individual

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Asian Pacific Journal of Tropical Medicine 2011年第1期4卷 81-82页

作者： Parveen Rana Kundu sk Mathur Sunita singh Amrita Duhan Garima Aggarwal Rajeev Sen Department of Pathology Pt.B.D.Sharma PGIMSIndia

Tuberculosis(TB) of the spleen is an extremely rare clinical entity particularly among immunocompetent *** report a case of isolated tuberculous abscess of spleen in a 13- years- old *** primary focus of infection was detected in lungs or any other *** patient was treated by splenectomy after a therapeutic failure with standard antituberculous medication.

关键词： Spleen Tuberculosis Abscess