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Journal of Arid Land 2014年第1期6卷 117-127页

作者： silvia CLAVER Susana L SILNIK Florencia F CAMPóN Entomology Lab IADIZA-CONICET

Livestock ranching is one of the main productive activities in arid regions of the *** produces changes in animal as well as plant communities(***,abundance and species dominance relationships).Ants are good biological indicators due to the environmental fidelity of some of their community *** described the functional structure of the ant community in the central Monte of Mendoza,Argentina,and examined the effect of grazing using richness,diversity and the functional group *** used pitfall traps to sample ants at a reserve with 30-year cattle exclusion and at an adjacent *** of the 27 recorded species showed significant differences in their abundance and two species were absent at the *** richness and diversity did not reflect these differences,functional groups *** Climate Specialists were more abundant at the ranch while Cryptic Species and Generalized Myrmicinae increased at the *** study supports the utility of the functional group scheme to study the effects of grazing disturbance in ant communities of arid regions.

关键词： ants cattle grazing functional groups richness diversity arid zones Monte Desert

Guided resonance in negative index photonic crystals: a new approach

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Light(Science & Applications) 2014年第1期3卷 365-369页

作者： silvia Romano Stefano Cabrini Ivo Rendina Vito Mocella CNR-IMM-Unita di Napoli 80131 NapoliItaly Molecular Foundry Lawrence Berkeley National LaboratoryBerkeleyCAUSA

The behavior of a negative refraction photonic crystal slab irradiated with out-of-plane incident beam is an unexplored *** such an experimental configuration,guided mode resonance appears in the reflection *** show that,in this case,the light coupled inside the photonic crystal is backpropagating.A relationship with the negative index properties is established using a new approach in which the guided resonance is recovered by modeling the photonic crystal layer with a simple Lorentz resonator using the Fresnel reflection formula.

关键词： diffraction gratings guided mode resonance negative index photonic crystals

Enzymatic Hydrolysis of Sugarcane Biomass and Heat Integration as Enhancers of Ethanol Production

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Journal of Renewable Materials 2018年第2期6卷 183-194页

作者： Reynaldo Palacios-Bereche Adriano Ensinas Marcelo Modesto silvia Nebra Centre of Engineering Modelling and Applied Social SciencesFederal University of ABC(CECS/UFABC)Santo AndréSPBrazil Energy Department Federal University of LavrasLavras MGBrazil Interdisciplinary Centre of Energy Planning University of Campinas(NIPE/UNICAMP)CampinasSPBrazil

The aim of this study is to assess the possibility of increasing ethanol production by introducing the bagasse hydrolysis process into conventional *** were performed for mass and energy balances using Aspen Plus?*** was assumed that sugarcane trash and lignin cake—hydrolysis process residues—are available as supplementary *** cases were evaluated,including:(a)conventional ethanol distillery,(b)conventional plant combined with a hydrolysis process without heat integration,with different solid contents in the hydrolysis reactor,and(c)conventional plant combined with the hydrolysis process applying heat integration by pinch *** highest ethanol yield was achieved in the case of heat integration and concentration of cellulose hydrolysate by the membrane system with a solid content of 5%in the hydrolysis *** represents an increase of 22%over conventional distilleries currently found in the industry.

关键词： Ethanol sugarcane enzymatic hydrolysis heat integration

Kounis syndrome:a clinical entity penetrating from pediatrics to geriatrics

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Journal of Geriatric Cardiology 2020年第5期17卷 294-299页

作者： Mattia Giovannini Ioanna Koniari Francesca Mori silvia Ricci Luciano De Simone silvia Favilli Sandra Trapani Giuseppe Indolfi Nicholas George Kounis Elio Novembre Allergy Unit Department of Pediatrics Meyer Children’s University Hospital Electrophysiology and Device Department University Hospital of South Manchester NHS Foundation Trust Department of Health Sciences University of Florence Meyer Children’s Hospital Pediatric Cardiology Unit Meyer Children’s University Hospital Department of Neurofarba University of Florence Meyer Children’s Hospital Department of Cardiology Patras University School of Medicine

1 Introduction Kounis syndrome constitutes a coronary hypersensitivity disorder defined by the association of an anaphylactoid,anaphylactic,allergic or hypersensitivity reaction with an acute coronary syndrome,in a physiopathological context involving various interrelated and interacting inflammatory cells,such as mast-cells,eosinophils and platelets.[1,2]Similar entities to Kounis syndrome might involve cerebral and mesenteric arteries.

关键词： Age Classification Coronary artery disease Kounis syndrome Myocardial infarction

Comparison of sperm parameters and DNA fragmentation index between infertile men with infection and vaccines of COVID-19

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Asian Journal of Andrology 2023年第5期25卷 578-582页

作者： silvia W Lestari Gito Restiansyah Evy Yunihastuti Gita Pratama Department of Medical Biology.Faculty of Medicine.Universitas Indonesia-Cipto Mangunkusumo Hospital.Jakarta 10430 Indonesia Department of Internal Medicine Faculty of MedicineUniversitas Indonesia-Cipto Mangunkusumo HospitalJakarta 10430.Indonesia Department of Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo HospitalJakarta 10430Indonesia

Several preventive measures,including vaccination,have been implemented owing to the severe global effect of coronavirus disease 2019(COVID-19),but there is still limited evidence in the effect of this disease and vaccination against it on male ***,this study is to compare sperm parameters of infertile patients with or without COVID-19 infection and the effect of COVID-19 vaccine types on *** samples of infertile patients were collected consecutively at Universitas Indonesia-Cipto Mangunkusumo Hospital(Jakarta,Indonesia).COVID-19 was diagnosed by rapid antigen or polymerase chain reaction(PCR)*** was performed with three types of vaccine,namely inactivated viral vaccine,messenger RNA(mRNA)vaccine,and viral vector *** were then analyzed on the World Health Organization recommendations,and DNA fragmentation was assayed with the sperm chromatin dispersion *** results showed that the COVID-19 group experienced a significant decrease in sperm concentration and progressive motility(both P0.05).The viral vector vaccine caused a decrease in morphology as well as an increase in DFI compared with the control(both P0.05).We conclude that COVID-19 has negative effects on sperm parametes and sperm DNA fragmentation,and we found that the viral vector vaccines affect sperm parameter values and DNA fragmentation *** studies with a larger population and longer follow-up are needed to confirm the results.

关键词： COVID-19 semen parameter sperm DNA fragmentation sperm quality vaccines

Assessing the response of human primary macrophages to defined fibrous architectures fabricated by melt electrowriting

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Bioactive Materials 2023年第3期21卷 209-222页

作者： Carlotta Mondadori Amit Chandrakar silvia Lopa Paul Wieringa Giuseppe Tal`o silvia Perego Giovanni Lombardi Alessandra Colombini Matteo Moretti Lorenzo Moroni IRCCS Istituto Ortopedico Galeazzi Cell and Tissue Engineering LaboratoryMilanItaly Complex Tissue Regeneration Department MERLN Institute for Technology-Inspired Regenerative MedicineMaastrichtthe Netherlands IRCCS Istituto Ortopedico Galeazzi Laboratory of Experimental Biochemistry and Molecular BiologyMilanItaly Department of Athletics Strength and ConditioningPozna´n University of Physical EducationPozna´nPoland IRCCS Istituto Ortopedico Galeazzi Orthopaedic Biotechnology LabMilanItaly Regenerative Medicine Technologies Lab Ente Ospedaliero CantonaleBellinzonaSwitzerland Service of Orthopaedics and Traumatology Department of SurgeryEnte Ospedaliero CantonaleLuganoSwitzerland Euler Institute Faculty of Biomedical SciencesUniversit`a della Svizzera ItalianaLuganoSwitzerland

The dual role of macrophages in the healing process depends on macrophage ability to polarize into phenotypes that can propagate inflammation or exert anti-inflammatory and tissue-remodeling *** scaf-fold geometry has been proposed as a strategy to influence macrophage behavior and favor the positive host response to ***,we fabricated Polycaprolactone(PCL)scaffolds by Melt Electrowriting(MEW)to investigate the ability of scaffold architecture to modulate macrophage *** human macrophages unpolarized(M0)or polarized into M1,M2a,and M2c phenotypes were cultured on PCL films and MEW scaffolds with pore geometries(square,triangle,and rhombus grid)characterized by different angles.M0,M2a,and M2c macrophages wrapped along the fibers,while M1 macrophages formed clusters with rounded *** bridges were formed only for angles up to 90◦.No relevant differences were found among PCL films and 3D scaffolds in terms of surface ***206 and CD163 were highly expressed by M2a and M2c macrophages,with M2a macrophages presenting also high levels of CD86.M1 macrophages expressed moderate levels of all *** rhombus architecture promoted an increased release by M2a macrophages of IL10,IL13,and sCD163 compared to PCL *** proangiogenic factor IL18 was also upregulated by the rhombus configuration in M0 and M2a macrophages compared to PCL *** interesting findings obtained for the rhombus architecture represent a starting point for the design of scaffolds able to modulate macrophage phenotype,prompting investigations addressed to verify their ability to facilitate the healing process in vivo.

关键词： Macrophage Melt electrowriting Additive manufacturing Scaffold design Scaffold geometry

In vitro models of retinal diseases

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Annals of Eye Science 2022年第1期7卷 106-113页

作者： Martina Lucchesi silvia Marracci Department of Biology University of PisaPisaItaly

Background:Continuous and primary in vitro cultures are largely used to study cellular mechanisms occurring in several pathologic-like or pathological *** cell lines allow to perform long-lasting experiments since they do not undergo ***:The immortalized Moorfields/Institute of Ophtalmology-Müller 1(MIO-M1)cell type represents a valuable model to analyze the mechanistic pathways characterizing Müller glial cells,both in health and in ***-M1 can be used to dissect the response of these glial cells following treatments which mimic pathological *** instance,MIO-M1 are useful to study the response of this cell type to stress condition as the case of oxidative stress(OS)(cultured with hydrogen peroxide),pathological neovascularization(cultured with VEGF),hypoxic or hyperoxic condition(cultured in low or high oxygen chamber).On the other hand,primary cultures allow to specifically analyze cellular responses without the interference of the whole organ,although the experimental treatment is performed in *** Müller cells can be used to perform electrophysiological analyses of different cell ***:We describe how to manage MIO-M1 cells and how to analyze their response to different stress conditions;moreover,we report how to isolate and identify primary Müller cells and how to perform patch clamp and single cell recordings on them.

关键词： Müller cells Moorfields/Institute of Ophtalmology-Müller 1(MIO-M1) primary culture

Stem cell-based 3D brain organoids for mimicking, investigating, and challenging Alzheimer's diseases

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Neural Regeneration Research 2022年第2期17卷 330-332页

作者： Federica Cordella Carlo Brighi Alessandro Soloperto silvia Di Angelantonio Center for Life Nanoscience Istituto Italiano di TecnologiaRomeItaly Department of Physiology and Pharmacology Sapienza UniversityRomeItaly

Alzheimer's disease(AD) is a progressive and irreversible neurodegene rative disorder that causes a decline of cognitive functions and a deterioration of behavioral and social performances. According to current estima... 详细信息

关键词： Alzheimer diseases irreversible

Spatial and temporal patterns of forest fires in the Central Monte:relationships with regional climate

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Ecological Processes 2024年第1期13卷 66-79页

作者： Pablo Eugenio Villagra Erica Cesca Leandro Manuel Alvarez silvia Delgado Ricardo Villalba Instituto Argentino de Nivología Glaciología y Ciencias Ambientales–CONICET-CCT Mendoza Facultad de Ciencias Agrarias Universidad Nacional de Cuyo

Background Natural and anthropogenic wildfires burn large areas of arid and semi-arid forests with significant socio-economic and environmental impacts. Fire regimes are controlled by climate, vegetation type, and anthropogenic factors such as ignition sources and human-induced disturbances. Projections of climate and land-use change suggest that these controlling factors will change, altering fire regimes in the near future. In the southern Central Monte, Mendoza, Argentina, the factors that modulate the fire temporal and spatial variability are poorly understood. We reconstructed the fire history of southeast of Mendoza from 1984 to 2023 and investigated the relationships between fire extent and climate variability at seasonal and interannual scales. Burned areas were determined using Google Earth Engine by processing Landsat 5-TM, Landsat 7-ETM+, and Landsat 8-OLI-TIRS sensor *** The region exhibited high spatial and temporal variability in fire occurrence, being a mosaic of areas with different fire histories and recovery times. Between 1985 and 2023, fire recurrence ranged from sites unburned to sites with up to 14 fires. The occurrence of large fires was strongly favored by a combination of a year with abundant spring–early summer precipitation, which favors fuel accumulation, followed by a year of low spring–early summer precipitation. Precipitation and burnt area showed a very pronounced 6–7 year cycle, suggesting a dominant climatic control on fire *** Fire distribution in southeastern Mendoza forests is not homogeneous, resulting in a mosaic of patches with different fire histories. This heterogeneity may be related to vegetation patterns and land use. The temporal variability of fires is strongly influenced by climate variability, which would promote fuel production and subsequent drying. Large fires are concentrated in periods of high interannual precipitation variability. Climate change scenarios predict an increase in tem

关键词： Fire recurrence Fire mapping Recovery time Climate Dry forest Wildfire

Occurrence of human pathogenic viruses in drinking water and in its sources:A review

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Journal of Environmental Sciences 2023年第10期132卷 145-161页

作者： Marco Panizzolo Marta Gea Elisabetta Carraro Giorgio Gilli silvia Bonetta Cristina Pignata Department of Public Health and Pediatrics University of TorinoPiazza Polonia 9410126TorinoItaly Department of Life Sciences and Systems Biology University of Torinovia Accademia Albertina 1310123TorinoItaly

Since many waterborne diseases are caused by human pathogenic viruses,virus monitoring of drinking water(DW)and DW sources is crucial for public ***,the aim of this review was to describe the occurrence of human pathogenic viruses in DW and DW sources;the occurrence of two viruses proposed as novel indicators of human faecal contamination(Peppermild mottle virus and Tobacco mosaic virus)was also *** research was focused on articles that assessed viral occurrence using molecular methods in the surface water used for DW production(SW-D),groundwater used for DW production(GW-D),DW and bottled-DW(BW).A total of 1544 studies published in the last 10 years were analysed,and 79 were ultimately *** considering the detection methods,filtration is the most common concentration technique,while quantitative polymerase chain reaction is the most common quantification *** virus occurrence in SW-D,GW-D,and DW,high percentages of positive samples were reported for adenovirus,polyomavirus and Pepper mild mottle *** genomes were frequently detected in SW-D and rarely in GW-D,suggesting that GW-D may be a safe DW *** genomes were also detected in DW,posing a possible threat to human *** lowest percentages of positive samples were found in Europe,while the highest were found in Asia and South *** three articles assessed viral occurrence in *** review highlights the lack of method standardization and the need for legislation updates.

关键词： Drinking water Enteric virus Human health Microbial water quality Molecular methods Surface water