Stem cell-based 3D brain organoids for mimicking, investigating, and challenging Alzheimer's diseases

作     者：Federica Cordella Carlo Brighi Alessandro Soloperto Silvia Di Angelantonio Federica Cordella;Carlo Brighi;Alessandro Soloperto;Silvia Di Angelantonio

作者机构：Center for Life NanoscienceIstituto Italiano di TecnologiaRomeItaly Department of Physiology and PharmacologySapienza UniversityRomeItaly 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2022年第17卷第2期

页      面：330-332页

核心收录：

学科分类：1002[医学-临床医学] 100203[医学-老年医学] 10[医学] 

主　　题：Alzheimer diseases irreversible 

摘      要：Alzheimer s disease(AD) is a progressive and irreversible neurodegene rative disorder that causes a decline of cognitive functions and a deterioration of behavioral and social performances. According to current estimations, AD is considered the prevalent cause of dementia, accounting for 60% and 80% of cases every year.