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D-Psicose intake exacerbates dextran sulfate sodium-induced colitis in mice through alteration in the gut microbiota and dysfunction of mucosal barrier

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Food Science and Human Wellness 2024年第1期13卷 173-182页

作者： Xuejiao Zhang Ang Li Yuanyifei wang Jin wang Bowei Zhang Yan Zhang Jingmin Liu shuo wang Tianjin Key Laboratory of Food Science and Health School of MedicineNankai UniversityTianjin 300072China College of Food Science and Technology Hebei Agricultural UniversityBaoding 071001China

D-Psicose,as a low-calorie rare sugar,has attracted a lot of attention in recent years for alternating to *** anti-obesity effect of D-psicose has been extensively confirmed in previous studies,however,the impact of D-psicose on colitis remains ***,we firstly evaluated the effect of the D-psicose prophylactic intervention on dextran sulfate sodium-induced colitis in C57BL/6 *** pathological symptoms,inflammatory cytokines levels,gut microbiota composition,short chain fatty acids(SCFAs)production and colonic barrier integrity were comprehensively *** results confirmed that D-psicose intervention aggravated colitis,characterized by the exacerbation of colon shortening,increase of colonic inflammatory infiltration,and marked exaltation of disease activity indices and IL-6,IL-1βand TNF-α***,the dysfunction of gut microbiota was identified in the psicose *** abundance of pro-inflammatory bacteria Lachnospiraceae_NK4A136_group was significantly up-regulated while the abundance of probiotics Akkermansia and Lactobacillus were significantly down-regulated in the psicose group compared to the model ***,the production of SCFAs was suppressed in the psicose group,accompanied by a decrease in the level of mucin 2(Muc-2).Collectively,the underlying mechanism of the exacerbation of colitis by D-psicose intervention might be attributed to microbiota dysfunction accompanied by the reduction of SCFAs,which leads to the damage of the mucosal barrier and the intensifi cation of inflammatory invasion.

关键词： D-Psicose Colitis Gut microbiota Short chain fatty acids Mucin 2

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Electromagnetic transitions in multiple chiral doublet bands

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Chinese Physics C 2016年第12期40卷 91-98页

作者： Hui Jia Bin Qi Shou-Yu wang shuo wang Chen Liu Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment Institute of Space Sciences Shandong University Weihai 264209 China

Multiple chiral doublet bands （MχD） in the 80, 130 and 190 mass regions are studied by the model of γ=90°triaxial rotor coupled with identical symmetric proton-neutron configurations. By selecting a suitable basis, the calculated wave functions are explicitly exhibited to be symmetric under the operator A, which is defined as rotation by 90° about the 3-axis with the exchange of valance proton and neutron. We found that both M1 and E2 transitions are allowed between levels with different values of A, while they are forbidden between levels with same values of A. Such a selection rule holds true for MχD in different mass regions.

关键词： chiral doublet bands electromagnetic transition selection rule particle rotor model

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Lipid metabolism, amino acid metabolism, and prostate cancer: a crucial metabolic journey

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Asian Journal of Andrology 2024年第2期26卷 123-134页

作者： Lin Chen Yu-Xin Xu Yuan-shuo wang Jian-Liang Zhou School of Pharmacy Hangzhou Normal UniversityHangzhou 311121China Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province Hangzhou Normal UniversityHangzhou 311121China School of Pharmacy Guangxi Medical UniversityNanning530021China

Prostate cancer(PCa)is one of the most common malignancies in males worldwide,and its development and progression involve the regulation of multiple metabolic *** in lipid metabolism affect the proliferation and metastatic capabilities of PCa *** cells increase lipid synthesis and regulate fatty acid oxidation to meet their growth and energy ***,changes occur in amino acid metabolism in *** cells exhibit an increased demand for specific amino acids,and they regulate amino acid transport and metabolic pathways to fulfill their proliferation and survival *** changes are closely associated with disease progression and treatment response in PCa ***,a comprehensive investigation of the metabolic characteristics of PCa is expected to offer novel insights and approaches for the early diagnosis and treatment of this disease.

关键词： amino acid metabolism lipid metabolism metabolic pathways prostate cancer treatment strategies

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Awake craniotomy for auditory brainstem implant in patients with neurofibromatosis type 2:Four case reports

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World Journal of Clinical Cases 2021年第25期9卷 7512-7519页

作者： De-Xiang wang shuo wang Min-Yu Jian Ru-Quan Han Department of Anesthesiology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China

BACKGROUND The auditory brainstem implant(ABI)is a significant treatment to restore hearing sensations for neurofibromatosis type 2(NF2)***,there is no ideal method in assisting the placement of *** this case series,intraoperative cochlear nucleus mapping was performed in awake craniotomy to help guide the placement of the electrode *** SUMMARY We applied the asleep-awake-asleep technique for awake craniotomy and hearing test via the retrosigmoid approach for acoustic neuroma resections and ABIs,using mechanical ventilation with a laryngeal mask during the asleep phases,utilizing a ropivacaine-based regional anesthesia,and sevoflurane combined with propofol/remifentanil as the sedative/analgesic agents in four NF2 *** electrode arrays were placed in the awake phase with successful intraoperative hearing tests in three *** was one uncooperative patient whose awake hearing test needed to be *** all cases,tumor resection and ABI were performed *** electrode effectiveness was achieved in awake ABI *** This case series suggests that awake craniotomy with an intraoperative hearing test for ABI placement is safe and well *** craniotomy is beneficial for improving the accuracy of ABI electrode placement and meanwhile reduces non-auditory side effects.

关键词： Awake craniotomy Neurofibromatosis type 2 Auditory brainstem implant Hearing test Case report

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Study on mechanism of increased allergenicity induced by Ara h 3 from roasted peanut using bone marrow-derived dendritic cells

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Food Science and Human Wellness 2023年第3期12卷 755-764页

作者： Minjia wang shuo wang Xiaodong Sun Zhirui Deng Bing Niu Qin Chen School of Life Sciences Shanghai UniversityShanghai 200444China Medical School Shanghai UniversityShanghai 200444China

Little information was so far available about allergenic mechanism of the roasted peanut allergens during initial stages of *** purpose of this study was to determine the influence of roasting(150℃,20 min)on biochemical and biological properties of Ara h 3,a major peanut *** of roasted peanut emulsion to mice,differences in uptakes between Ara h 3 purified from raw peanuts(named as Ara h 3-Raw)and that purified from roasted peanuts(named as Ara h 3-Roasted)by bone marrow-derived dendritic cells(BMDCs)and the implication of cell surface receptors involving in uptake,and changes in glycosylation and structure of Ara h 3 after roasting were analyzed in this *** study suggested that roasting increased allergenicity of peanut to BALB/c *** reaction and structural changes of Ara h 3 induced by roasting significantly altered the uptake of Ara h 3-Roasted by BMDCs,and modified Ara h 3 fate in processes involved in immunogenicity and hyper allergenicity,indicating that food processing pattern can change food allergenicity.

关键词： Roasted peanut Ara h 3 Bone marrow-derived dendritic cells(BMDCs) Allergenicity Maillard reactions

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Composite laminar membranes for electricity generation from water evaporation

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Nano Research 2024年第1期17卷 307-311页

作者： Xiao wang Gang Yuan Han Zhou Yu Jiang shuo wang Jiaojiao Ma Chongyang Yang Sheng Hu State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials(iChEM)College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China

Harvesting clean energy from water evaporation has been extensively investigated due to its *** achieve high efficiency,energy conversion materials should contain multiple features which are difficult to be simultaneously obtained from single-component *** we use composite laminar membranes assembled by nanosheets of graphene oxide and mica,and find a sustained power density induced by water evaporation that is two orders of magnitude larger than that from membranes made by either of the *** power output is attributed to selective proton transport driven by water evaporation through the interlayer nanochannels in the *** process relies on the synergistic effects from negatively charged and hydrophilic mica surfaces that are important for proton selectivity and water transport,and the tunable electrical conductivity of graphene oxide that provides optimized internal *** demonstrated composite membranes offer a strategy of enhancing power generation by combining the advantages from each of their components.

关键词： graphene oxide mica water evaporation electrical double layer surface charge ion selectivity

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A meaningful learning method for zero-shot semantic segmentation

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Science China(Information Sciences) 2023年第11期66卷 35-53页

作者： Xianglong LIU Shihao BAI Shan AN shuo wang Wei LIU Xiaowei ZHAO Yuqing MA State Key Lab of Software Development Environment Beihang University JD Health International Inc.

Zero-shot semantic segmentation, which is developed to segment unseen categories, has attracted increasing attention due to its strong practicability. Previous approaches usually applied semantic-visual mapping based on seen categories to unseen categories, and thus failed to generate meaningful unseen visual representations and struggled to balance the seen and unseen concepts in the classifier. To overcome the above limitations, we propose a novel meaningful learning method that could be embedded into any generationbased zero-shot semantic segmentation model, borrowing the idea from the educational psychology field. The proposed meaningful learning method refers to the process that the new concepts could be learned by relating to existing comprehensible concepts and harmoniously incorporated into the concept schema. Specifically, we introduce a generator with conjugate conceptual correlation(G3C) which generates meaningful unseen visual information through anchoring into existing concepts. Moreover, simulating the rational thinking mechanism,we introduce a fast-slow concept modulator to alleviate the noisy over-correlation problem introduced by G3C and further construct a comprehensive concept schema. Extensive experiments conducted on three benchmarks demonstrate the superior performance of our method, especially according to the commonlyacknowledged h-m Io U(e.g., 4% improvement on the Pascal-VOC dataset).

关键词： meaningful learning zero-shot learning semantic segmentation conjugate conceptual correlation fast-slow conceptual modulator

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Effects of Ti-and Nb-based transition element from single to multiple compound oxides and carbon-based composite additives on Mg-MgH2 hydrogen storage material

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Tungsten 2025年第1期 32-49页

作者： Li-Rong Xiao Chen Chen shuo wang Zi-Yin Dai Hideo Kimura Cui Ni Chuan-Xin Hou Xue-Qin Sun Si-Jie Guo Wei Du Xiu-Bo Xie School of Environmental and Material Engineering Yantai University Bosch HUAYU Steering Systems (Yantai) Co. Ltd.Ytp/MFE University of Tennessee Knoxville Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta Shandong University of Aeronautics

MgH2is considered as a promising hydrogen storage material for its high hydrogen storage capacity,low cost and abundant resource ***,the low kinetics and high enthalpy formation of MgH2limit its wide *** the perspective of adding catalysts to enhance the hydrogen storage properties of Mg-MgH2,this article elaborated the main catalysts based on Ti and Nb transition elements,including single oxide catalysts,binary oxides catalysts（combined with Ni,Na,Sr,V,etc.）,multiple catalysts bound to carbon,and composite catalysts with Ti and Nb elements combined with MXene ***,the main pathways of various catalysts to reduce the reaction activity and broaden the hydrogen desorption channel were also *** Ti-based catalysts can enhance the reactive sites of the matrix by forming multivalent states,while Nb-based catalysts broaden the hydrogen reaction channels by forming tiny *** improving the size structure and enhancing the grain size stability,combined with carbon materials should be the future considerations.

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Neoproterozoic(750–711 Ma)Tectonics of the South Qinling Belt,Central China:New Insights from Geochemical,Zircon U-Pb Geochronological,and Sr-Nd Isotopic Data from the Niushan Complex

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Acta Geologica Sinica(English Edition) 2023年第1期97卷 106-121页

作者： wang shuo LIU Yunhua YANG Benzhao TAN Le LI Xiaoyan DENG Nan School of Earth Sciences and Resources Chang'an UniversityXi'an 710054China Geological Team No.1 of Shaanxi Bureau of Geology and Mineral Resources AnkangShannxi 725000 China Longshou Mine of Jinchuan Group Co. LtdJinchangGansu 737100China Xi'an Mineral Resources Survey Center China Geological SurveyXi'an 710100China

The Xiejiaba and Fuqiangbei plutons form part of the newly identified Neoproterozoic Niushan complex,which is located in the southern South Qinling belt(SQB).The plutons are compositionally similar,were emplaced at 750–711Ma,and provide insights into Neoproterozoic tectonism within the South Qinling *** Xiejiaba pluton contains diorite,quartz diorite,granodiorite,and granite phases,all of which are sub-alkaline and have variable major element compositions with negative correlations between SiO_(2)and MgO,TFe_(2)O_(3),Al_(2)O_(3),CaO,TiO_(2)and P_(2)O_(5).These rocks are enriched in light rare earth elements(LREEs)and large ion lithophile elements(LILEs)and have negative Nb,Ta,P and Ti anomalies,all of which are indicative of arc-type *** Fuqiangbei pluton contains granitoids that are compositionally similar to the rocks in the Xiejiaba *** from these plutons have similarε_(Nd)(t)values(1.24–5.99)but very variable(^(87)Sr/^(86)Sr)i values(0.7010–0.7054).Combining these data with the geochemical data for these rocks suggests that the magmas that formed the Niushan complex were derived from the crust–mantle ***,combined with the results of previous research,suggests that the transition from low pressure-low temperature to low pressure-high temperature conditions within a subduction zone caused melting during a period of late subduction and backarc *** constrain the timing of subduction within the South Qinling belt and the northern Yangtze Block(YB)to 750–711 Ma,with this Neoproterozoic subduction associated with an ocean to the north overprinting an existing continental rift-type tectonic setting within the northern margin of the Yangtze Block and the South Qinling belt.

关键词： geochronology geochemistry magmatism tectonics Precambrian South Qinling

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Instability of solution-processed perovskite films:origin and mitigation strategies

Materials Futures

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Materials Futures 2023年第1期2卷 26-59页

作者： shuo wang Ming-Hua Li Yan Jiang Jin-Song Hu Beijing National Laboratory for Molecular Sciences(BNLMS) Institute of ChemistryChinese Academy of SciencesBeijing 100190People’s Republic of China School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China

Perovskite solar cells(PSCs)are promising next-generation photovoltaics due to their unique optoelectronic properties and rapid rise in power conversion ***,the instability of perovskite materials and devices is a serious obstacle hindering technology *** quality of perovskite films,which is an important prerequisite for long-term stable PSCs,is determined by the quality of the precursor solution and the post-deposition treatment performed after perovskite ***,we review the origin of instability of solution-processed PSCs from the perspectives of the precursor solutions and the perovskite *** addition,we summarize the recent strategies for improving the stability of the perovskite ***,we pinpoint possible approaches to further advance their long-term stability.

关键词： stability perovskite solar cells precursor solution perovskite films degradation

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