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老年腹部手术患者术后亚谵妄综合征预测模型的构建

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中华护理杂志 2024年第16期59卷 2001-2008页

作者：陈顺利刘琰陈静汤灵宇宋如蔡璐瑶郑思琳西南医科大学附属医院儿外科四川省泸州市646000 西南医科大学附属医院妇科四川省泸州市646000 西南医科大学附属医院肝胆外科四川省泸州市646000 西南医科大学附属医院手术室四川省泸州市646000 西南医科大学附属医院综合外科病房四川省泸州市646000 西南医科大学附属医院护理部四川省泸州市646000 四川省医学科学院·四川省人民医院肿瘤三

目的分析老年腹部手术患者术后亚谵妄综合征发生的影响因素并构建预测模型。方法采用便利抽样法,选取2022年2月—10月在四川省某三级甲等医院行腹部外科手术的497例老年患者作为调查对象,采用单因素和多因素Logistic回归分析探讨术后亚... 详细信息

目的分析老年腹部手术患者术后亚谵妄综合征发生的影响因素并构建预测模型。方法采用便利抽样法,选取2022年2月—10月在四川省某三级甲等医院行腹部外科手术的497例老年患者作为调查对象,采用单因素和多因素Logistic回归分析探讨术后亚谵妄综合征发生的影响因素,使用R软件构建预测模型并绘制列线图。用受试者操作特征曲线下面积和Hosmer-Lemshow检验及校准图评价模型的区分度及校准度。结果多因素Logistic回归结果显示,年龄(OR=1.066)、社会功能活动问卷得分(OR=1.143)、术后使用镇痛泵(OR=5.811)、术后留置肛管(OR=2.276)和术后输血(OR=4.322)是术后亚谵妄综合征发生的独立影响因素。构建的预测模型在建模组和验证组中的P值均>0.05,受试者工作特征曲线下面积分别为0.734、0.691。结论该研究构建的老年腹部手术患者术后亚谵妄综合征预测模型具有较好的校准度和区分度,可以辅助临床医护人员识别术后亚谵妄综合征发生的高危患者,为制订预防和干预措施提供参考依据。

关键词：老年人术后亚谵妄综合征腹部手术预测模型列线图护理

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术后亚谵妄危险因素的研究进展

黑龙江医学 2024年第1期48卷 121-125页

作者：陈顺利郑思琳西南医科大学护理学院四川泸州646000 西南医科大学附属医院四川泸州646000

目的:术后亚谵妄(Postoperative subsyndromal deliriom,PSSD)是手术患者较常见的术后并发症,与术后住院时间延长、认知功能下降、死亡率上升等多种不良后果有关。临床上暂缺乏有效的预防和治疗措施,其症状隐匿不易被识别,临床上对PSSD... 详细信息

目的:术后亚谵妄(Postoperative subsyndromal deliriom,PSSD)是手术患者较常见的术后并发症,与术后住院时间延长、认知功能下降、死亡率上升等多种不良后果有关。临床上暂缺乏有效的预防和治疗措施,其症状隐匿不易被识别,临床上对PSSD的认识较缺乏,增加术后PSSD患者管理难度。本研究通过回顾国内外关于PSSD研究的文献,为PSSD的早期发现和有效预防提供参考。方法:通过文献检索,系统综述PSSD的发生现状和危险因素。结果:本文分别从社会人口学因素,术前、术中和术后因素等方面总结了PSSD发生的高危因素,如高龄、文化水平、日常生活能力、认知功能、营养状态、药物使用、术前合并症、手术时间、术后疼痛、感染、身体约束等。结论:PSSD发生率高、危害大,是多因素综合作用的结果,临床工作者应加强对高危PSSD患者的重视和管理,促进术后患者的早期康复。

关键词：术后亚谵妄危险因素综述

Fractional-order difference curvature-driven fractional anisotropic diffusion equation for image super-resolution

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International Journal of Modeling, Simulation, and Scientific Computing 2019年第1期10卷 177-189页

作者： Xuehui Yin shunli chen Liping Wang Shangbo Zhou School of Software and Engineering Chongqing University of Posts and Telecommunications Chongqing 400065 P.R.China Key Laboratory of Dependable Service Computing in Cyber Physical Society Ministry of Education Chongqing University Chongqing 400030P.R.China College of Computer Science Chongqing University Chongqing 400030P.R.China

Image super-resolution methods-based existing edge indicating operators—namely Gauss curvature,mean curvature and gradient-cannot effectively identify the edges,ramps and flat regions and suffer from the loss of fine *** address these issues,this paper presents a fractional anisotropic diffusion equation based on a new edge indicator,named fractional-order difference curvature,which can characterize the intensity variations in *** introduce the frequency-domain definition for fractional-order derivative by the Fourier transform,which is easy to implement *** new edge indicator is better than the existing edge indicating operators in distinguishing between ramps and edges and can better handle the fine *** results for natural images validate that the proposed method can yield a visually pleasing result and better values of MSSIM and PSNR.

关键词： Image super-resolution fractional differentiation difference curvature anisotropic diffusion

腹腔镜阑尾切除术治疗小儿急性化脓性阑尾炎的临床效果分析

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中国社区医师 2024年第18期40卷 38-40页

作者：王兴吴玉宝陈顺利临沂市临沭县人民医院小儿外科山东临沂276700

目的:分析腹腔镜阑尾切除术治疗小儿急性化脓性阑尾炎的临床效果。方法:选取2021年5月—2023年5月临沭县人民医院收治的急性化脓性阑尾炎患儿150例作为研究对象,随机分为参照组(n=70)和分析组(n=80)。参照组实施开腹阑尾切除术,分析组... 详细信息

目的:分析腹腔镜阑尾切除术治疗小儿急性化脓性阑尾炎的临床效果。方法:选取2021年5月—2023年5月临沭县人民医院收治的急性化脓性阑尾炎患儿150例作为研究对象,随机分为参照组(n=70)和分析组(n=80)。参照组实施开腹阑尾切除术,分析组实施腹腔镜阑尾切除术。比较两组炎性指标、应激反应、并发症发生情况。结果:术前,两组重组人白细胞介素-1β(IL-1β)、白细胞计数(WBC)、C反应蛋白(CRP)、肿瘤坏死因子(TNF-α)水平比较,差异无统计学意义(P>0.05);术后1 d,两组IL-1β、WBC、CRP、TNF-α水平低于术前,且分析组低于参照组,差异有统计学意义(P0.05);术后3 h,两组HR、MAP、COR、SOD、MDA水平高于术前,但分析组低于参照组,差异有统计学意义(P<0.05)。分析组并发症总发生率低于参照组,差异有统计学意义(P=0.015)。结论:腹腔镜阑尾切除术治疗小儿急性化脓性阑尾炎的临床效果显著,可减轻炎性反应、应激反应,降低并发症发生率。

关键词：儿童急性化脓性阑尾炎腹腔镜阑尾切除术

不同体位对腹腔镜胆囊切除术病人麻醉恢复期呼吸及舒适度的影响

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护理研究 2024年第15期38卷 2675-2682页

作者：汤灵宇陈顺利蔡璐瑶陈颖异宋建英胡黎欣郑思琳西南医科大学附属医院四川646000 西南医科大学

目的:研究不同体位对腹腔镜胆囊切除术(LC)病人麻醉恢复期呼吸及舒适度的影响。方法:采用便利抽样法选取2022年1月-10月在西南医科大学附属医院行腹腔镜胆囊切除术的236例病人,随机分为A组(去枕平卧位)、B组(15°半卧位)、C组(30°半卧... 详细信息

目的:研究不同体位对腹腔镜胆囊切除术(LC)病人麻醉恢复期呼吸及舒适度的影响。方法:采用便利抽样法选取2022年1月-10月在西南医科大学附属医院行腹腔镜胆囊切除术的236例病人,随机分为A组(去枕平卧位)、B组(15°半卧位)、C组(30°半卧位)、D组(渐进性半卧位),各59例。比较4组拔除喉罩2 h内的血氧饱和度、呼吸频率、呼气峰流速(PEF)、用力呼气量(FVC)、第1秒用力呼气量(FEV_(1))、FEV_(1)/FVC、最大吸气压(MIP)、最大呼气压(MEP)、呼吸道并发症和舒适度。结果:B组、C组和D组在拔除喉罩1 h和2 h的PEF、FVC、FEV_(1)、MIP、MEP均高于A组(P0.05)。结论:腹腔镜胆囊切除术病人拔除喉罩后取15°半卧、30°半卧、渐进性半卧均利于病人肺通气和呼吸力学效应,且舒适度更好。其中30°半卧和渐进性半卧更利于呼吸肌做功,渐进性半卧舒适度最佳。

关键词：腹腔镜胆囊切除术麻醉恢复期体位呼吸舒适度护理

以家庭为中心的孤独症患儿照顾者健康教育方案的构建及应用

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现代临床护理 2024年第1期23卷 35-42页

作者：万小红康小庆陈顺利郭渠莲西南医科大学附属医院儿科(儿童血液肿瘤与出生缺陷实验室四川省出生缺陷临床医学研究中心)四川泸州646000

目的构建以家庭为中心的孤独症患儿照顾者健康教育方案,并探讨其应用效果。方法通过文献回顾和德尔菲法进行2轮专家函询,构建以家庭为中心的孤独症患儿照顾者健康教育方案。并采用不同病例前-后对照的方法,将2022年1月至2022年10月本... 详细信息

目的构建以家庭为中心的孤独症患儿照顾者健康教育方案,并探讨其应用效果。方法通过文献回顾和德尔菲法进行2轮专家函询,构建以家庭为中心的孤独症患儿照顾者健康教育方案。并采用不同病例前-后对照的方法,将2022年1月至2022年10月本院门诊收治的40例孤独症照顾者设为对照组,2022年11月至2023年1月门诊收治的40例设为观察组。对照组照顾者接受传统宣教,观察组照顾者接受以家庭为中心的孤独症患儿照顾者健康教育方案,比较两组患者照顾者照顾负担、健康教育知识掌握程度和患儿临床症状评估。结果两轮专家函询问卷回收率为100.00%。构建的照顾者健康教育方案第一轮函询专家权威系数0.875;第二轮函询专家权威程度系数0.900;各指标协调程度的变异系数0.04~0.20;两轮的Kendall协调系数W分别为0.794,0.786。方案内容包括照顾者培训、以家庭为中心的亲职照护和调动孤独症照护者积极情绪3部分。观察组与对照组各40例孤独症照顾者完成研究,干预后观察组孤独症家庭照顾者照护负担低于对照组,健康教育知识掌握程度高于对照组,患儿临床症状评估优于对照组,两组比较,差异具有统计学意义(均P<0.05)。结论构建以家庭为中心的孤独症患儿照顾者健康教育方案具有一定的科学性、适用性,可为孤独症家庭照顾者提供健康教育指导,提高健康教育知识掌握程度,降低照顾负担。

关键词：孤独症家庭照顾者健康教育以家庭为中心德尔菲法

Expression and subcellular localization of cysteine- and glycine-rich protein-2 in rat undifferentiated olfactory stem cells

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Neural Regeneration Research 2008年第5期3卷 558-560页

作者： Xue Gao Zengyu Cao Jun chen shunli Liu Dingjun Zha Feng Wang Yang chen Li Qiao Lianjun Lu Jianhua Qiu Department of Otorhinolaryngology Head and Neck Surgery Xijing Hospital the Fourth Mifitary Medical University Xi＇an 710032 ShaanxiProvince China

BACKGROUND： As a member of the LIM protein family Ⅱ, cysteine- and glycine-rich protein-2 （CRP2） has been demonstrated to play a role in the regulation of growth and differentiation of eukaryotic cells. Our previous study has demonstrated that CRP2 can be detected in the embryonic rat inner ear but not in the adult rat inner ear. However, at present, the expression of LIM protein family H members in stem or precursor cells has not been described. OBJECTIVE： To determine the expression and sub-cellular localization of CRP2 in olfactory stem cells. DESIGN, TIME AND SETTING： An experiment with repeated measures was performed in the Laboratory of Otorhinolaryngology, Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University from February 2008 to April 2008. MATERIALS： Olfactory stem cells, and rabbit-anti-CRP2 polyclonal antibody were prepared and kept in our laboratory. METHODS： Reverse transcription polymerase chain reaction and Western blot analysis were used to detect expression of CRP2 in olfactory stem cells. Immunocytochemistry was also used to localize CRP2 in olfactory stem cells. MAIN OUTCOME MEASURES： The expression and sub-cellular localization of CRP2 in rat olfactory stem cells. RESULTS： CRP2 expression was found in olfactory stem cells, and CRP2 was distributed in both the nucleus and the cytoplasm. CONCLUSION： Confirmation of the expression and distribution of CRP2 in olfactory stem cells.

关键词： cysteine- and glycine-rich protein-2 LIM domain subcellular localization olfactory stem cells

A hybrid data driven framework considering feature extraction for battery state of health estimation and remaining useful life prediction

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Green Energy and Intelligent Transportation 2024年第2期3卷 50-59页

作者： Yuan chen Wenxian Duan Yigang He shunli Wang Carlos Fernandez School of Artificial Intelligence Anhui UniversityHefei 230009China State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130022China School of Electrical Engineering and Automation Wuhan UniversityWuhan 430000China School of Information Engineering Southwest University of Science and TechnologyMianyang 621010China School of Pharmacy and Life Sciences Robert Gordon UniversityAberdeenAB10-7GJUK

Battery life prediction is of great significance to the safe operation,and reduces the maintenance *** paper proposes a hybrid framework considering feature extraction to achieve more accurate and stable life prediction performance of the *** feature extraction,eight features are obtained to fed into the life prediction *** hybrid framework combines variational mode decomposition,the multi-kernel support vector regression model and the improved sparrow search algorithm to solve the problem of data backward,uneven distribution of high-dimensional feature space and the local escape ability,*** parameters of the estimation model are obtained by introducing the elite chaotic opposition-learning strategy and adaptive weights to optimize the sparrow search *** algorithm can improve the local escape ability and convergence performance and find the global *** comparison is conducted by dataset from National Aeronautics and Space Administration which shows that the proposed framework has a more accurate and stable prediction *** with other algorithms,the SOH estimation accuracy of the proposed algorithm is improved by 0.16%–1.67%.With the advance of the start point,the RUL prediction accuracy of the proposed algorithm does not change much.

关键词： State of heath Improved sparrow search algorithm Remaining useful life Variational mode decomposition Multi-kernel support vector regression Feature extraction

Correlative Analysis between Contents of Nutrients and Secondary Substances in Damaged Pinus massoniana Needles and Population Parameters of Dendrolimus kikuchii(Lepidoptera:Lasiocampidae)

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Plant Diseases and Pests 2014年第4期5卷 13-19,25页

作者： Tong Wengang chen shunli Zhou Suo chen Delan Forestry Diseases and Pests Control and Quarantine Station of Liancheng County College of Forestry Fujian Agriculture and Forestry University College of Life Science and Technology Nanyang Normal University Forest Bureau of Wuyishan City

In order to explore the effects of chemical substances changes in damaged masson pine （Pinus massoniana） needles on population dynamics of Dendroli- mus kikuchii, D. kikuchii larvae were reat~ with P. massoniana needles with different damage degrees （mild, moderate and severe）, and its population parame- ters and contents of nutrients and secondary substances in damaged P. massoniana needles were measured, and the integrated correlation coefficient was adopted for data analysis. The results showed that with the damage degree aggravating, flavones in needles increased accordingly, while contents of soluble sugars, polysaeeha- rides and proteins decreased. The average developmental duration and mortality of D. kikuchii larvae increased with the damage degree increasing. No significant correlation was found between the changes in contents of tannins or total phenols and the developmental duration or mortality of each instar larvae. There were signif- icant direct and integrated correlations between contents of nutrients and secondary substances of P. massoniana needles and the developmental duration or mortality of each instar larvae except the 6＇h instar larvae. With the damage degree increasing, all parameters of D. kikuchii population including body weight of the 7~ instar larvae, average feeding capacity of larvae, pupal weight, pupation rate, female ratio and fecundity decreased. No significant correlation was found between the changes in contents of tannins or total phenols and population parameters of D. kikuchii larvae. The results suggest that the contents of nutrients and secondary sub- stances in P. ,mssoniana needles dramatically influenced the population parameters of D. kikuchii, and the importance from high to low successively was soluble sugars 〉 proteins 〉 polysaccharides 〉 flavones. Contents of tannins and total phenols seemed to have little influence.

关键词： Dendrolimus kikuchii Pinus massoniana Nutrients Secondary substances Population parameters Integrated correlation coefficient