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Nano Research 2024年第8期17卷 7068-7076页

作者： Shucheng Liu yu shuai Xiaosi Qi Zhao Ding Yi Liu College of Big Data and Information Engineering Guizhou UniversityGuiyang 550025China College of Physics Guizhou Province Key Laboratory for Photoelectrics Technology and ApplicationGuizhou UniversityGuiyang 550025China

Modulation of metal sites coordination can significantly refine the electronic architecture of catalysts,thereby improving their catalytic *** work successfully developed a core–shell Co@N-doped porous carbon(Co@NC)catalyst by pyrolyzing the COF/MOF(IISERP-COF3/ZIF-67)composite in an inert *** Co@NC catalyst exhibited impressive oxygen evolution reaction(OER)performance,with a small overpotential of 304 mV and a modest Tafel slope of 88.6 mV·dec^(−1)in a 1 M KOH,alongside remarkable stability,maintaining 98.5%of its activity over 13 *** role of IISERP-COF3 was pivotal in preventing Co atom aggregation during the ZIF-67 pyrolysis,which facilitated the creation of mesopores for enhanced mass transport and ***,it effectively modulated the Co-N coordination to fine-tune the electronic structure,thereby optimizing the catalyst's capacity for adsorption of intermediates and boosting its intrinsic *** functional theory(DFT)studies corroborate that the exceptional OER efficiency of Co@NC can be linked to the enhanced Co-N coordination,optimizing the localized electronic structure at the Co active *** study not only proposes an innovative approach for optimizing COF/MOF as effective electrocatalysts but also clears the path for the emergence of affordable,high-performance alternatives to precious metal-based catalysts,marking a significant advancement in sustainable energy technologies.

关键词： covalent organic framework(COF) metal-organic framework(MOF) core-shell structure catalysts oxygen evolution reaction

The clinical features and potential mechanisms of cognitive disorders in peripheral autoimmune and inflammatory diseases

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Fundamental Research 2024年第2期4卷 226-236页

作者： Ke-qi Fan Tao Huang Jian-shuai yu Yi-yuan Li Jin Jin MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences InstituteZhejiang UniversityHangzhou 310058China Department of Gastroenterology Sir Run Shaw HospitalCollege of Medicine Zhejiang UniversityHangzhou 310016China Key Laboratory for Developmental Genes and Human Disease Ministry of EducationInstitute of Life SciencesJiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjing 210096China

According to a study from World Health Organization’s Global Burden of Disease,mental and neurological disorders have accounted for 13%of global diseases in recent years and are on the *** conditions or neuroinflammatory disorders are linked by the presence of an exaggerated immune response both peripherally and in the central nervous system(CNS).Cognitive dysfunction(CD)encompasses a complex group of diseases and has frequently been described in the field of autoimmune diseases,especially in multiple non-CNS-related autoimmune *** studies have provided various hypotheses regarding the occurrence of cognitive impairment in autoimmune diseases,including that abnormally activated immune cells can disrupt the integrity of the blood-brain barrier(BBB)to trigger a central neuroinflammatory *** the BBB is intact,autoantibodies and pro-inflammatory molecules in peripheral circulation can enter the brain to activate microglia,inducing CNS inflammation and ***,the mechanisms explaining the association between the immune system and neural function and their contribution to diseases are *** this review,we used clinical statistics to illustrate the correlation between CD and autoimmune diseases that do not directly affect the CNS,summarized the clinical features and mechanisms by which autoimmune diseases trigger cognitive impairment,and explored existing knowledge regarding the link between CD and autoimmune diseases from the perspective of the field of neuroimmunology.

关键词： Autoimmune diseases Neuroinflammation Central nervous system dysfunction Autoantibodies Inflammatory cytokines

Ionic liquid-based in situ dynamically self-assembled cationic lipid nanocomplexes(CLNs)for enhanced intranasal siRNA delivery

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Chinese Chemical Letters 2024年第7期35卷 367-371页

作者： Luyu Zhang Zirong Dong shuai yu Guangyue Li Weiwen Kong Wenjuan Liu Haisheng He Yi Lu Wei Wu Jianping Qi Key Laboratory of Smart Drug Delivery of MOE School of PharmacyFudan UniversityShanghai 201203China School of Pharmacy Shandong Academy of SciencesQilu University of TechnologyJi'nan 250353China College of Chemical Engineering North China University of Science and TechnologyTangshan 063210China

This research aims to develop a non-invasive strategy for small interfering RNA(siRNA)nasal delivery based on ionic liquids(ILs)and cationic lipid(2,3-dioleoyloxy-propyl)-trimethylammonium-chloride(DOTAP).Other than the classical role of penetration enhancer,ILs also acted as superior solvents to simultaneously load siRNA and DOTAP,forming siRNA-DOTAP-ILs(siRNA-DILs)*** nasal mucosa penetration,DOTAP and ILs components self-assembled into cationic lipid nanocomplexes to load siRNA for enhanced in situ *** siRNA-DILs demonstrated resistance against RNase,significant mucosa penetration,prolonged nasal retention,and satisfying gene-silencing efficacy at lower ***,DILs were also able to deliver KCa3.1-targeted siRNA effectively for the treatment of allergic rhinitis in rat model by nasal ***,DILs have great potentials to deliver biological macromolecules across nasal mucosa by in situ dynamic self-assembly.

关键词： Ionic liquids Cationic lipids Lipid nanoparticles siRNA Allergic rhinitis

Recent advances in Fe-N-C-and Co-N-C-based materials as bifunctional electrocatalysts for oxygen reduction and oxygen evolution

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Science China Chemistry 2024年第4期67卷 1137-1160页

作者： Hui-Min Xu Hong-Rui Zhu Chen-Jin Huang Zhi-Jie Zhang Ting-yu shuai Qi-Ni Zhan Gao-Ren Li College of Materials Science and Engineering Sichuan UniversityChengdu 610065China

Fe-nitrogen-carbon(Fe-N-C)-and Co-nitrogen-carbon(Co-N-C)-based electrocatalysts have been widely concerned because of their high OER/ORR activity,low metal cost,and simple *** exploration of Fe-N-C and Co-N-C single atombased catalysts with high activity and stability to overcome the slow kinetics of oxygen reduction and oxygen evolution reactions is also the key to the development of efficient electrolytic water,fuel cells,and rechargeable metal-air ***-N-C and Co-N-C single atom-based electrocatalysts have the advantages of a high utilization rate of metal atoms and high electrocatalytic activity,and are ideal catalysts for promoting electrochemical energy conversion and *** general principles of designing Fe-N-C and Co-N-C single atom-based electrocatalysts are reviewed in this ***,the strategies to improve the bifunctional catalytic activity and stability are ***,the challenges and prospects of Fe-N-C and Co-N-C single atom-based catalysts are well *** review will provide a reference for the directed optimization of Fe-N-C and Co-N-C single atom-based catalysts.

关键词： Fe-N-C Co-N-C single atom bifunctional oxygen electrocatalysts

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论环境行政专业性判断的司法审查构造

行政法学研究 2024年第2期 167-176页

作者：张帅宇北京航空航天大学法学院、柏林洪堡大学法学院北京100191

环境行政专业性判断是行政机关在环境风险规制领域中作出的专业性裁量,难以用传统司法实务上的实体性审查方法和程序性审查方法对其施加法律控制。通过行政机关的理由说明义务履行,法院可以过程性审查方法对环境行政专业性判断在推理环... 详细信息

环境行政专业性判断是行政机关在环境风险规制领域中作出的专业性裁量,难以用传统司法实务上的实体性审查方法和程序性审查方法对其施加法律控制。通过行政机关的理由说明义务履行,法院可以过程性审查方法对环境行政专业性判断在推理环节和论证过程中的重要节点予以检视,以考虑因素与操作方法是否适当来实施司法审查。环境行政专业性判断的审查阶段分为对判断基准和对基准客观适用的二阶层过程性审查,对判断基准的审查重点应放在客观考虑因素和完整裁量逻辑,对判断基准客观适用的审查重点应放在个案中的风险调查和风险评估。

关键词：环境行政风险规制专业性判断过程性审查

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肉桂酸衍生物的太赫兹光谱及弱相互作用分析

红外与毫米波学报 2024年第2期43卷 207-214页

作者：郑转平赵帅宇刘榆杭曾方西安邮电大学电子工程学院陕西西安710121

利用太赫兹时域光谱技术(THz-TDS)测试了对羟基肉桂酸(PCA)、反式-2-羟基肉桂酸(OCA)和4-氟肉桂酸(4-FCA)三种肉桂酸的衍生物(CADs)在0.5~3.5 THz范围内的吸收峰。基于密度泛函理论(DFT),借助振动模式自动关联判定方法(VMARD)对三种样品... 详细信息

利用太赫兹时域光谱技术(THz-TDS)测试了对羟基肉桂酸(PCA)、反式-2-羟基肉桂酸(OCA)和4-氟肉桂酸(4-FCA)三种肉桂酸的衍生物(CADs)在0.5~3.5 THz范围内的吸收峰。基于密度泛函理论(DFT),借助振动模式自动关联判定方法(VMARD)对三种样品THz吸收峰的来源进行了指认。最后采用分子力场能量分解法(EDAFF)分析了分子体系的弱相互作用力形式,通过VMD绘制原子着色图进行了可视化分析,并研究了其原子在分子体系中对弱相互作用力的贡献类型和强弱。研究结果表明,基于THz-TDS、DFT与VMARD、EDA-FF方法结合不但能有效地辨别同分异构体及结构近似的有机分子,而且也能为其生化功能揭示提供有价值的参考数据。

关键词：太赫兹时域光谱密度泛函理论肉桂酸衍生物振动模式能量分解法

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国际中文教育志愿者岗前培训效果影响研究

河北开放大学学报 2024年第2期29卷 90-93页

作者：于帅辽东学院人文与教育学院辽宁丹东118001

国际中文教育志愿者是传播好中国声音的“青年助力军”。探索志愿者岗前培训效果影响因素,可以增强志愿者项目整体效能。在扎根理论指导下,运用Nvivo 14软件对近三年的45名志愿者进行半开放式访谈,归纳总结出影响岗前培训效果的核心范... 详细信息

国际中文教育志愿者是传播好中国声音的“青年助力军”。探索志愿者岗前培训效果影响因素,可以增强志愿者项目整体效能。在扎根理论指导下,运用Nvivo 14软件对近三年的45名志愿者进行半开放式访谈,归纳总结出影响岗前培训效果的核心范畴分别是志愿者特性、管理模式、课程质量,构建了志愿者岗前培训效果影响因素(即VMC)模型。最后,从整体布局和可行性操作方面入手,对培训点提出提升策略和改善建议。

关键词：国际中文教育志愿者岗前培训影响因素扎根理论

从一个县看新时代农村文学——以鄂西北汉江中游的谷城县域文学创作为例

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社会科学动态 2024年第7期 104-107页

作者：帅瑜谷城县作家协会中国作家协会湖北谷城441700

文学是人学,也是人民的精神食粮。文学的发展,也如同耕种稼禾一样,需要适宜的气候,良好的环境。中国农村人口占全国人口一半以上,广袤的农村应该是文学创作的沃野,是文学大有作为的地方,也是需求文学的大市场。然而,农民文学作者和作品... 详细信息

文学是人学,也是人民的精神食粮。文学的发展,也如同耕种稼禾一样,需要适宜的气候,良好的环境。中国农村人口占全国人口一半以上,广袤的农村应该是文学创作的沃野,是文学大有作为的地方,也是需求文学的大市场。然而,农民文学作者和作品并没有广泛涌现,文学事业在农村还没有普遍发展起来,文学创作也没有真正开展起来,文学的发展现状不尽人意。农村文学荒芜,农民作家匮乏,这种现象再也不能持续下去了。以地处鄂西北汉江中游的谷城县域为考察个案,研究发现繁荣农村文学事业,首先要有党委、政府真金白银的鼎力支持,其次要有文联、作协、乡镇宣传和文化部门的积极作为。文学应该是劳动人民的文学,文学创作应该是大众参与的创作,尤其是不能缺少我们这个农业大国的农民参与。

关键词：新时代农村文学县域

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血栓渗透性在急性缺血性卒中的研究进展

中华神经科杂志 2024年第3期57卷 298-302页

作者：王晓翠俞帅张航肖国栋苏州大学附属第二医院神经内科苏州215004 苏州市立医院(南京医科大学附属苏州医院)神经内科苏州215002

在急性缺血性卒中患者中,堵塞血管的血栓成分存在差异。患者的一些影像学征象与血栓成分相关,例如血栓渗透性,高渗透性血栓与红细胞密度较高、纤维蛋白密度较低相关。血栓的不同成分和机械特性可能会对治疗效果和风险产生影响。因此,文... 详细信息

在急性缺血性卒中患者中,堵塞血管的血栓成分存在差异。患者的一些影像学征象与血栓成分相关,例如血栓渗透性,高渗透性血栓与红细胞密度较高、纤维蛋白密度较低相关。血栓的不同成分和机械特性可能会对治疗效果和风险产生影响。因此,文中总结了血栓渗透性与缺血性卒中生物学、影像学特征关系的相关研究,探讨血栓渗透性在急性缺血性卒中患者治疗中的临床意义,为神经内科医生提供参考和帮助。

关键词：卒中渗透性机械取栓神经影像学血栓成分

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地质矿产绿色勘查及找矿技术的探究

世界有色金属 2024年第3期 47-49页

作者：董帅语内蒙古地质工程有限责任公司内蒙古呼和浩特010010

本文简单分析了地质矿产绿色勘察及找矿技术在推动地质矿产行业革新进步、满足生态环保要求、提升勘查及找矿工作效率等方面的重要价值,阐述了应用实践中应遵循的统筹规划原则、特殊性原则以及重点性原则,并对遥感技术、GPS感应技术、X... 详细信息

本文简单分析了地质矿产绿色勘察及找矿技术在推动地质矿产行业革新进步、满足生态环保要求、提升勘查及找矿工作效率等方面的重要价值,阐述了应用实践中应遵循的统筹规划原则、特殊性原则以及重点性原则,并对遥感技术、GPS感应技术、X射线荧光技术、同位找矿技术等技术的应用要点进行探讨。

关键词：地质矿产行业绿色勘查及找矿技术遥感技术 GPS感应技术

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