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Single-image night haze removal based on color channel transfer and estimation of spatial variation in atmospheric light

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Defence Technology（防务技术） 2023年第7期25卷 134-151页

作者： shu-yun liu Qun Hao Yu-tong Zhang Feng Gao Hai-ping Song Yu-tong Jiang Ying-sheng Wang Xiao-ying Cui Kun Gao Key Laboratory of Photoelectronic Imaging Technology and System Ministry of EducationSchool of Optics and PhotonicsBeijing Institute of TechnologyBeijing100081China China North Vehicle Research Institute BeijingChina

The visible-light imaging system used in military equipment is often subjected to severe weather conditions, such as fog, haze, and smoke, under complex lighting conditions at night that significantly degrade the acquired images. Currently available image defogging methods are mostly suitable for environments with natural light in the daytime, but the clarity of images captured under complex lighting conditions and spatial changes in the presence of fog at night is not satisfactory. This study proposes an algorithm to remove night fog from single images based on an analysis of the statistical characteristics of images in scenes involving night fog. Color channel transfer is designed to compensate for the high attenuation channel of foggy images acquired at night. The distribution of transmittance is estimated by the deep convolutional network DehazeNet, and the spatial variation of atmospheric light is estimated in a point-by-point manner according to the maximum reflection prior to recover the clear image. The results of experiments show that the proposed method can compensate for the high attenuation channel of foggy images at night, remove the effect of glow from a multi-color and non-uniform ambient source of light, and improve the adaptability and visual effect of the removal of night fog from images compared with the conventional method.

关键词： Dehazing image captured at night Chromaticity fusion correction Color channel transfer Spatial change-based atmospheric light estimation DehazeNet

Association of Bone Turnover Levels with MTHFR Gene Polymorphisms among Pregnant Women in Wuhan, China

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Current Medical Science 2018年第4期38卷 602-609页

作者： shu-yun liu Qin HUANG Xue GU Bin ZHANG Wei SHEN Ping TIAN yun ZENG Ling-zhi QIN Lin-xiang YE Ze-min NI Qi WANG Department of Epidemiology and Biostatistics MOE Key Lab of Environment and Health School of Public Health Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China Department of Rehabilitation Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China Wuhan Women and Children Medical Care Center Wuhan 430016 China Women and Children Medical Center of Jiang-an District Wuhan 430017 China

Pregnancy is a critical stimulator of bone mineral resorption. We used to find the MTHFR gene polymorphisms are related with blood lead levels among pregnant women. Pregnancy-stimulated bone turnover may be associated with MTHFR gene polymorphisms too. In this article, we aimed to determine the relationship between MTHFR gene polymorphisms and bone turnover rates among the pregnant women. The participants including pregnant and non-pregnant women were selected and recruited during their routine prenatal or physical examination from July to October in 2012. A total of 1000 participants, including 250 pregnant women in the first, second, and third trimesters and 250 non-pregnant women, were enrolled in the study. Finally, after excluding 27 participants unable to provide blood samples, 973 eligible participants （i.e., 234, 249, and 248 pregnant women in the first, second, and third trimesters, respectively, and 242 non-pregnant women） were included in the research. The MTHFR gene 1298CC homozygote carriers were more susceptible to yield higher plasma homocysteine levels than the 1298AA/AC carriers, with standardized coefficients of 0.086 （P〈0.05） and 0.104 （P〈0.01） of all the participants and the pregnant women, respectively. The MTHFR gene 1793AA homozygote carriers more likely showed higher plasma osteocalcin levels （standardized β=0.091, P〈0.01） than the 1793GG/GA carriers among all the subjects. Plasma homocysteine levels were positively correlated with blood lead levels among the participants and the pregnant women with standardized coefficients of 0.320 （P〈0.01） and 0.179 （P〈0.01）, respectively. Plasma osteocalcin levels were positively associated with blood lead levels among pregnant and non-pregnant women with standardized coefficients of 0.084 （P〈0.05） and 0.125 （P〈0.01）, respectively. In conclusion, homocysteine and osteocalcin contents in plasma are associated with the MTHFR gene A1298C polymorphism and blood lead levels among pregnant women. The MTHFR gene

关键词： pregnant women bone turnover levels blood lead levels MTHFR gene polymorphism

Different protein expression patterns in rat spinal nerves during wallerian degeneration assessed using isobaric tags for relative and absolute quantitation proteomics profiling

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Neural Regeneration Research 2020年第2期15卷 315-323页

作者： shuai Wei Xue-Zhen Liang Qian Hu Wei-Shan Wang Wen-Jing Xu Xiao-Qing Cheng Jiang Peng Quan-Yi Guo shu-yun liu Wen Jiang Xiao Ding Gong-Hai Han Ping liu Chen-Hui Shi Yu Wang The First Affiliated Hospital of Medical College Shihezi UniversityShiheziXinjiang Uygur Autonomous RegionChina Institute of Orthopedics Chinese PLA General HospitalBeijingChina Co-Innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina The First Clinical Medical School Shandong University of Traditional Chinese MedicineJinanShandong ProvinceChina Kunming Medical University KunmingYunnan ProvinceChina Shanxi Medical University TaiyuanShanxi ProvinceChina

Sensory and motor nerve fibers of peripheral nerves have different anatomies and regeneration functions after injury. To gain a clear understanding of the biological processes behind these differences, we used a labeling technique termed isobaric tags for relative and absolute quantitation to investigate the protein profiles of spinal nerve tissues from Sprague-Dawley rats. In response to Wallerian degeneration, a total of 626 proteins were screened in sensory nerves, of which 368 were upregulated and 258 were downregulated. In addition, 637 proteins were screened in motor nerves, of which 372 were upregulated and 265 were downregulated. All identified proteins were analyzed using the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis of bioinformatics, and the presence of several key proteins closely related to Wallerian degeneration were tested and verified using quantitative real-time polymerase chain reaction analyses. The differentially expressed proteins only identified in the sensory nerves were mainly relevant to various biological processes that included cell-cell adhesion, carbohydrate metabolic processes and cell adhesion, whereas differentially expressed proteins only identified in the motor nerves were mainly relevant to biological processes associated with the glycolytic process, cell redox homeostasis, and protein folding. In the aspect of the cellular component, the differentially expressed proteins in the sensory and motor nerves were commonly related to extracellular exosomes, the myelin sheath, and focal adhesion. According to the Kyoto Encyclopedia of Genes and Genomes, the differentially expressed proteins identified are primarily related to various types of metabolic pathways. In conclusion, the present study screened differentially expressed proteins to reveal more about the differences and similarities between sensory and motor nerves during Wallerian degeneration. The present findings could provide a reference point for a fut

关键词： gene ontology Kyoto Encyclopedia of Genes and Genomes isobaric tags for relative and absolute quantitation motor nerve proteomics sensory nerve spinal nerve Wallerian degeneration

Prophylactic Antitumor Effect of Mixed Heat Shock Proteins/Peptides in Mouse Sarcoma

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Chinese Medical Journal 2015年第16期128卷 2234-2241页

作者： Yu Wang shu-yun liu Mei Yuan Yu Tang Quan-Yi Guo Xue-Mei Cui Xiang Sui Jiang Peng Institute of Orthopedics Chinese People's Liberation Army General Hospital Beijing 100853 China

Background：To develop a vaccine-based immunotherapy for sarcoma,we evaluated a mixture of heat shock proteins （mHSPs） as a vaccine for sarcoma treatment in a mouse *** shock protein/peptides （HSP/Ps） are autoimmune factors that can induce both adaptive and innate immune responses;HSP/Ps isolated from tumors can induce antitumor immune activity when used as ***：In this study,we evaluated the effects of mHSP/Ps on prophylactic antitumor *** extracted mHSP/Ps,including HSP60,HSP70,GP96,and HSP l 10,from the mouse sarcoma cell lines S 180 and MCA207 using *** immunity induced by mHSP/Ps was assessed using flow cytometry,ELISPOT,lactate dehydrogenase release,and enzyme-linked immunosorbent ***：Of S180 sarcoma-beating mice immunized with mHSP/Ps isolated from S180 cells,41.2% showed tumor regression and long-term survival,with a tumor growth inhibition rate of 82.3% at 30 *** MCA207 sarcoma-bearing mice immunized with mHSP/Ps isolated from MCA207 cells,50% showed tumor regression and long-term survival with a tumor growth inhibition rate of 79.3%.All control mice died within 40 *** proportions of natural killer cells,CD8＋,and interferon-γ-secreting cells and tumor-specific cytotoxic T-lymphocyte activity were increased in the immunized ***：Vaccination with a polyvalent mHSP/P cancer vaccine can induce an immunological response and a marked antitumor response to autologous *** mHSP/P vaccine exerted greater antitumor effects than did HSPT0,HSP60,or tumor lysates alone.

关键词： Heat Shock Protein/Peptides lmmunotherapy Prophylactic Sarcoraa Tumor Vaccine

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惯性信息辅助的快速大视角图像匹配方法

中国惯性技术学报 2016年第4期24卷 504-510页

作者：王云舒刘建业曾庆化刘昇南京航空航天大学自动化学院南京211106 卫星通信与导航协同创新中心南京211106 中航工业洛阳电光设备研究所洛阳471009

大视角图像匹配算法的鲁棒性与实时性直接影响飞行器对远距离目标定位的性能。针对目前仿射不变图像匹配算法实时性较差的问题,提出一种惯性信息辅助的快速大视角图像匹配方法。该方法对现有的快速图像匹配算法进行改进,避免了构建高斯... 详细信息

大视角图像匹配算法的鲁棒性与实时性直接影响飞行器对远距离目标定位的性能。针对目前仿射不变图像匹配算法实时性较差的问题,提出一种惯性信息辅助的快速大视角图像匹配方法。该方法对现有的快速图像匹配算法进行改进,避免了构建高斯金字塔,提高了算法效率。然后利用机载惯性导航信息求解实时图与参考图之间的单应性矩阵,并对实时图进行模拟视角变换以此减小图像间视角差异,克服了现有的大视角图像匹配算法盲目多次的匹配计算,实现了大视角图像的快速匹配。实验结果表明,惯性信息辅助的大视角图像匹配算法与现有的快速仿射不变性匹配算法相比,匹配效率提高了至少2倍。

关键词：大视角图像仿射不变性惯性导航图像匹配目标定位

Extracellular matrix from human umbilical cordderived mesenchymal stem cells as a scaffold for peripheral nerve regeneration

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Neural Regeneration Research 2016年第7期11卷 1172-1179页

作者： Bo Xiao Feng Rao Zhi-yuan Guo Xun Sun Yi-guo Wang shu-yun liu Ai-yuan Wang Quan-yi Guo Hao-ye Meng Qing Zhao Jiang Peng Yu Wang Shi-bi Lu Institute of Orthopedics Chinese PLA General HospitalBeijingChina Beijing Key Laboratory of Regenerative Medicine in Orthopedics BeijingChina The Neural Regeneration Co-innovation Center of Jiangsu Province NantongJiangsu ProvinceChina Department of Orthopedics First Affiliated HospitalSchool of MedicineShihezi UniversityShiheziXinjiang Uygur Autonomous RegionChina Department of Orthopedics Cangzhou Central HospitalCangzhouHebei ProvinceChina

The extracellular matrix,which includes collagens,laminin,or fibronectin,plays an important role in peripheral nerve ***,a Schwann cell-derived extracellular matrix with classical biomaterial was used to mimic the neural ***,extensive clinical use of Schwann cells remains limited because of the limited origin,loss of an autologous nerve,and extended in vitro culture *** the present study,human umbilical cord-derived mesenchymal stem cells（h UCMSCs）,which are easily accessible and more proliferative than Schwann cells,were used to prepare an extracellular *** identified the morphology and function of h UCMSCs and investigated their effect on peripheral nerve *** with a non-coated dish tissue culture,the h UCMSC-derived extracellular matrix enhanced Schwann cell proliferation,upregulated gene and protein expression levels of brain-derived neurotrophic factor,glial cell-derived neurotrophic factor,and vascular endothelial growth factor in Schwann cells,and enhanced neurite outgrowth from dorsal root ganglion *** findings suggest that the h UCMSC-derived extracellular matrix promotes peripheral nerve repair and can be used as a basis for the rational design of engineered neural niches.

关键词： umbilical Schwann regeneration scaffold neurotrophic biomaterial niche fibronectin glial engineered

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang Li Xiaomei Tang Jinyu Zeng Yige Song Chao Xu Kai Zhao Guoqiang liu Youming Lu Xinyan Li Kai shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

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音乐专业教学中的重要角色——“艺术指导”

天津音乐学院学报 2010年第3期 108-111页

作者：张淑珍刘芸天津师范大学音乐与影视学院

在音乐专业教学中,"艺术指导"这一角色逐渐被凸显出来,它是专业教学发展到一定阶段的必然产物;同时也是专业教学中不可或缺的重要角色。"艺术指导"的专业队伍建设和他们的学识水平,直接影响着专业教学成果的最终水平;对整体教学质量的... 详细信息

在音乐专业教学中,"艺术指导"这一角色逐渐被凸显出来,它是专业教学发展到一定阶段的必然产物;同时也是专业教学中不可或缺的重要角色。"艺术指导"的专业队伍建设和他们的学识水平,直接影响着专业教学成果的最终水平;对整体教学质量的提高起着重要的促进作用。

关键词：艺术指导角色作用

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山东大学开设文科物理课程的实践与思考

大学物理 2018年第8期37卷 44-46,64页

作者：于淑云刘建强山东大学物理学院山东济南250100

开设文科物理,是培养文科生的科学思维模式,加强文科生的科学素养的一个重要途径.本文针对文科物理"教什么?怎么教?"两个问题,从课程内容、授课模式、授课效果等几方面介绍在山东大学初次开设文科物理的情况.结果显示,联系日常生活、结... 详细信息

开设文科物理,是培养文科生的科学思维模式,加强文科生的科学素养的一个重要途径.本文针对文科物理"教什么?怎么教?"两个问题,从课程内容、授课模式、授课效果等几方面介绍在山东大学初次开设文科物理的情况.结果显示,联系日常生活、结合科技前沿的内容设计,课堂教学结合线上自学的教学模式,得到学生的认可和好评.

关键词：文科物理科学素养混合教学