检索结果-南通市图书馆

Hydrophobic long-chain two-dimensional perovskite scintillators for underwater X-ray imaging

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第1期43卷 175-185页

作者： Jin-Xiao Zheng Zi-An zhou Tiao Feng Hui Li Cheng-Hua Sun NüWang Yang Tian Yong Zhao shu-yun zhou Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Laboratory of Bioinspired Smart Interfacial Science and Technology of the Ministry of Education Beijing Key Laboratory of Bioinspired Energy Materials and DevicesSchool of ChemistryBeijing Advanced Innovation Center for Biomedical EngineeringBeihang UniversityBeijing 100191China Department of Engineering Physics Tsinghua University and Key Laboratory of Particle and Radiation Imaging Ministry of EducationTsinghua UniversityBeijing 100084China e-mail:yangt@***

The underwater X-ray imaging technology development is significant to subaqueous target reconnaissance/detection/identification, subfluvial archaeology,submerged resource exploration, etc. As the core of X-ray imaging detection, the scintillator has been plagued by inherent moisture absorption and decomposition, and strict requirements for seamless packaging and ***, we designed a manganese-doped two-dimensional(2D) perovskite scintillator modified by hydrophobic longchain organic amine through the combination of component and doping engineering. The modified perovskites show high water repellency that can be used as an underwater X-ray scintillator. X-ray images of aquatic organisms or other objects with a high spatial resolution of10 lp·mm^(-1) at a big view field(32 mm × 32 mm) were obtained by scintillation screen. This hydrophobic perovskite scintillator based on molecular design is of great promise in underwater X-ray nondestructive testing technology development.

关键词： Two-dimensional perovskite Hydrophobic Scintillators Underwater X-ray imaging Underwater nondestructive testing technology

急性髓系白血病患者外周血细胞中FLT3基因表达与FLT3/ITD突变的关系及其意义

在线全文

学校读者我要写书评

暂无评论

癌症 2009年第6期28卷 632-636页

作者：徐兵史鹏程宋小燕唐家宏周淑芸南方医科大学南方医院血液科广东广州510515

背景与目的:研究表明FLT3/ITD突变的急性髓性白血病(acute myeloid leukemia,AML)患者预后差,但关于AML患者FLT3基因的表达水平在预后中的作用及其与FLT3/ITD突变关系的研究尚不充分。本研究探讨初治AML患者FLT3基因的表达水平与FLT3/IT... 详细信息

背景与目的:研究表明FLT3/ITD突变的急性髓性白血病(acute myeloid leukemia,AML)患者预后差,但关于AML患者FLT3基因的表达水平在预后中的作用及其与FLT3/ITD突变关系的研究尚不充分。本研究探讨初治AML患者FLT3基因的表达水平与FLT3/ITD突变的关系及其临床意义。方法:建立实时荧光定量PCR检测FLT3基因表达水平及PCR检测FLT3/ITD突变的方法,分析79例初治AML患者FLT3基因水平、FLT3/ITD突变及与预后的关系。结果:22.7%(18/79)的AML患者存在FLT3/ITD突变。92.4%(73/79)的患者标本中可检测到FLT3基因表达,FLT3基因表达水平为0～7320,中位数为312,正常对照组未检测到FLT3基因的表达。FLT3基因高表达及FLT3/ITD突变AML组的白细胞计数及骨髓白血病细胞均显著高于低表达和无突变AML组(P0.05),FLT3/ITD突变AML患者FLT3基因表达中位数与无突变组比较差异也无统计学意义。FLT3/ITD突变组的完全缓解率(58.8%)显著低于无FLT3/ITD突变组(82.1%)(P0.05),但无FLT3/ITD突变组中,FLT3基因高表达组完全缓解率(69.2%)显著低于低表达组(93.3%)(P<0.05)。结论:FLT3高表达与FLT3/ITD突变之间无明显相关性,FLT3高表达对于无FLT3/ITD突变AML患者可能是一个预后不良的指标。

关键词：白血病髓细胞急性 FLT3 FLT3/ITD突变实时定量PCR

Laser direct writing of flexible multifunctional airflow sensors on the Kevlar fabric

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 443-454页

作者： Wei Wang Zi-Qing Chen Yong-Qi Li Yu-Long Wang Mei-Chen Liu yun-Bo Ruan Yang Zhang shu-Juan Liu Qiang Zhao College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Zhe Jiang Topsun Logistic Control CO. LTD.Yuhuan 317600China Department of Rehabilitation Medicine School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China

The growing interest in flexible devices has emerged as a global trend due to their advantages in flexibility,lightweight structure,and wearability,addressing the limitations of traditional *** wearable airflow sensors have been previously reported,the development of flexible fabric-based airflow sensors capable of functioning in environments with open flames—critical for fire rescue operations—has yet to be explored,largely due to the poor fire resistance of conventional *** this work,we first present a flexible,wearable,and multifunctional airflow sensor with excellent fire-resistant properties,fabricated through a simple direct laser writing *** sensor maintains airflow detection capabilities even in the presence of open ***,the fabrication of fabric-based sensors involves complex procedures such as carbon materials doping or vapor-phase deposition,leading to lengthy preparation cycles and high ***,fabric-based devices are inherently prone to *** address these challenges,we introduce twice-vertical laser-induced graphene(TVLIG)as a sensitive and reliable component for fire-resistant airflow *** resulting TVLIG/Kevlar fabric can be integrated into various garments,particularly protective suits,to form sensitive and fire-resistant airflow sensors capable of detecting airflow velocity and direction in both two-dimensional(2D)and three-dimensional(3D)spaces during fire ***,the TVLIG patterns can be expanded to multifunctional platforms,such as glucose detection for injured individuals,offering further applications in rescue *** functional expansion reduces the burden on rescue personnel and streamlines device *** its outstanding sensing capabilities,fire resistance,and expandability,the developed flexible airflow sensor shows great potential for various real-world rescue scenarios,promising advancements in wearable sensing technology for rescue enginee

关键词： flexible airflow sensor direct laser writing twice-vertical laser-induced graphene fire accident rescue Kevlar fabric

Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin zhou Dan Ma Yi-Xiang He Jing Jin Hong-Lian Wang yun-Feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

Ginseng Total Saponins Enhance Neurogenesis after Focal Cerebral Ischemia

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ginseng Total Saponins Enhance Neurogenesis after Focal Cere...

Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts

中华中医药学会第三次血栓病学术会议暨河南省中西医结合学会心血管病专业委员会、山东省中西医结合学会活血化瘀专业委员会年会、冠心病中医、中西医结合诊疗新进展学习班、全国心血管疾病中西医结合诊治新进展学习班

作者： Guo-qing Zheng,Wei Cheng,Yan Wang,Xiu-min Wang,shu-zhi Zhao,yun zhou,Shi-jue Liu,Xiao-tong Wang Center of Neurology and Rehabilitation,The Second Affiliated Hospital of Wenzhou Medical College,Wenzhou 325027,PR China

Background:Stroke is associated with high mortality and major disability burdens worldwide,but there are few effective and widely available *** is one of the most commonly used healing herbs for stroke and chronic debilitating conditions in *** are the main active principles of ginsengs efficacy,but the mechanisms have not been fully ***:To test the hypothesis that the administration of Ginseng Total Saponins(GTS) after focal cerebral ischemia may induce endogenous neural stem cells activation and adult central nervous system regeneration,and thereby improve neurological deficits. Methods:The rats were randomly divided into sham-operation(Sham) group,normal sodium(NS) group and GTS *** group and GTS group were further divided into four sub-groups according the time point 1d,3 d,7 d and 14 d with 8 rats per sub-group after the permanent middle cerebral artery occlusion(MCAO) insult. Rats in GTS groups received intraperitoneal injections of GTS dissolved at a dose of 25 mg·kg·*** in NS group were only received intraperitoneal injections of same amount *** injections of GTS or NS twice daily were start to perform 3 days before model establishment until the animals were *** sham animals received neither GTS nor *** neurological status of the awake rats was assessed blindly after model establishment at 1d,3d,7 d and 14 d, *** immunostaining and double staining were performed by following the 3-steps ***:A,GTS-treated rats have better neurological scores compared with those in normal saline(NS) group at 14 d time point(p<0.05);B, at 3d,7d and 14d time point,BrdU-positive cell numbers in GTS group were significantly higher than those in NS group in the ipsilateral subventricular zone(SVZ) after middle cerebral artery occlusion(MCAO)(p<0.05,or p<0.01);BrdU/NeuN cell numbers in GTS group also were significantly higher than those in NS group in the ipsilateral infarct area a

关键词： Focal cerebral ischemia Neurogenesis Neurological function Ginseng total saponins

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Traditional Medicine Research 2025年第1期10卷 73-81页

作者： Xiao-Long zhou Wei-Jin Jiang Ji Yu Mao-Jun Yao yun-Tong Li Hunan Provincial Key Laboratory of Research Resource Mining and High-valued Utilization on Edible&Medicinal PlantCollege of Chemistry and Chemical EngineeringJishou UniversityJishou 416000China Hunan Gaoge Dairy Co. Ltd.Changsha 410000China

Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in *** vine tea processing,a large amount of broken tea is produced,which has low commercial ***:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea ***:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid *** chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted ***,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE *** vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant ***:The findings suggest that extraction methods signi

关键词： vine tea dihydromyricetin ultrasonic-assisted extraction volatile aroma components

Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 483-484页

作者： yun Li Junfang Wu Department of Anesthesiology&Shock Trauma and Anesthesiology Research(STAR)CenterUniversity of Maryland School of MedicineBaltimoreMDUSA

Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability *** in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth *** survival changes have led neurotrauma researchers to examine how SCI interacts with brain *** health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关键词： alterations inflammation injury

Nanostructured ZnO/BiVO_(4)I-scheme heterojunctions for piezocatalytic degradation of organic dyes via harvesting ultrasonic vibration energy

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 488-497页

作者： Yiling Li Xiaoyao Yu Yingjie zhou Yao Lin Ying Wu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China

BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step *** resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure *** 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and *** enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole ***,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active ***,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.

关键词： piezoelectric catalytic heterojunction dye degradation ultrasonic vibration

FISH与RQ-PCR监测慢性髓系白血病患者造血干细胞移植后微小残留病

在线全文

学校读者我要写书评

暂无评论

癌症 2010年第2期29卷 207-211页

作者：朱红倩刘晓力宋兰林刘启发孟凡义周淑芸南方医科大学南方医院血液科广东广州510515

背景与目的:监测慢性髓系白血病(chronic myeloid leukemia,CML)的微小残留病(minimal residual disease,MRD)的常用方法有间期荧光原位杂交(interphase fluorescence in situ hybridization,FISH)和实时定量逆转录-聚合酶链反应(real-time quantitative reverse transcription PCR,RQ-PCR)。本研究分析用FISH和RQ-PCR两种方法在CML造血干细胞移植后不同时间点监测MRD的意义。方法:采用间期FISH和RQ-PCR技术,对31例异基因造血干细胞移植前后的CML患者骨髓细胞进行BCR-ABL融合基因定期监测,随访时间3～48个月。结果:31例患者移植后,前30个月各时间点FISH检测的阳性细胞数及RQ-PCR检测的BCR-ABL/ABL比值均较移植前明显下降,下降>2个对数值(P3个对数值(P<0.05)。结论:FISH和RQ-PCR方法检测BCR-ABL融合基因有较好的一致性。RQ-PCR连续监测MRD的敏感性更高,MDR的定量分析有利于评估疗效和指导个体化治疗。

关键词：慢性髓系白血病 BCR—ABL FISH PCR 移植