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Framework and Key Technologies of Human-machine Hybrid-augmented Intelligence System for Large-scale Power Grid Dispatching and Control

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 1-12页

作者： shixiong Fan Jianbo Guo Shicong Ma Lixin Li Guozheng Wang Haotian xu Jin Yang Zening Zhao China Electric Power Research Institute Beijing 100192China the Beijing Huairou Laboratory Beijing 101400China School of Engineering the University of GlasgowGlasgow G128QQUK

With integration of large-scale renewable energy,new controllable devices,and required reinforcement of power grids,modern power systems have typical characteristics such as uncertainty,vulnerability and openness,which makes operation and control of power grids face severe security *** of artificial intelligence(AI)technologies represented by machine learning in power grid regulation is limited by reliability,interpretability and generalization ability of complex *** of hybrid-augmented intelligence(HAI)based on human-machine collaboration(HMC)is a pivotal direction for future development of AI technology in this *** on characteristics of applications in power grid regulation,this paper discusses system architecture and key technologies of human-machine hybrid-augmented intelligence(HHI)system for large-scale power grid dispatching and control(PGDC).First,theory and application scenarios of HHI are introduced and analyzed;then physical and functional architectures of HHI system and human-machine collaborative regulation process are *** technologies are discussed to achieve a thorough integration of human/machine ***,state-of-theart and future development of HHI in power grid regulation are summarized,aiming to efficiently improve the intelligent level of power grid regulation in a human-machine interactive and collaborative way.

关键词： Artificial intelligence human-machine collaborative control human-machine hy brid intelligence optimization and evolution power grid dispatching and control

Numerical simulation of tumor-induced angiogenesis influenced by the extra-cellular matrix mechanical environment

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Acta Mechanica Sinica 2009年第6期25卷 889-895页

作者： Yan Cai Kalkabay Gulnar Hongyi Zhang Jinfeng Cao shixiong xu Quan Long Department of Mechanics and Engineering Science Fudan University 200433 Shanghai China Brunel Institute for Bioengineering School of Engineering and Design Brunel UniversityUxbridge Middlesex UK

To investigate tumor-induced angiogenesis under the influence of the mechanical environments inside and outside the tumor, mathematical model of tumor angiogenesis was developed. In the model, extra-cellular matrix （ECM） was treated as a thin plane. The displacement of ECM is obtained from the force balance equation consisted of the ECs traction, the ECM visco-elastic forces and the exter- nal forces. Simulation results show that a layered capillary network is obtained with a well vascularized region at the periphery of the tumor. The present model can be used as a valid theoretical method in the basic researches in tumorinduced angiogenesis.

关键词： Tumor-induced angiogenesis . Mechanical environment . 2D mathematical model

Enhancing osteogenic bioactivities of coaxial electrospinning nanoscaffolds through incorporating iron oxide nanoparticles and icaritin for bone regeneration

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Nano Research 2024年第7期17卷 6430-6442页

作者： Peng Wang Qianjin Wang Dengxian Wu Yunyang Zhang shixiong Kang xucai Wang Jiayu Gu Hao Wu Zhihong xu Qing Jiang School of Biomedical Engineering and Informatics Nanjing Medical UniversityNanjing 211166China State Key Laboratory of Pharmaceutical Biotechnology Department of Sports Medicine and Adult Reconstructive SurgeryNanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210008China Center of Modem Analysis Nanjing UniversityNanjing 210008China State Key Laboratory of Bioelectronics Jiangsu Key Laboratory for Biomaterials and DevicesSchool of Biological Science and Medical EngineeringSoutheast UniversityNanjing 210009China Co-Innovation Center for Efficient Processing and Utilization of Forest Resources College of Chemical EngineeringNanjing Forestry UniversityNanjing 210037China Jiangsu Institute of Metrology Nanjing 210023China

Bone tissue engineering provides a promising strategy for the treatment of bone ***,the clinical utilization of biomaterial-based scaffolds is constrained by their inadequate mechanical strength and absence of osteo-inductive ***,we proposed to endow nano-scaffold(NS)constructed by coaxial electrospinning technique with enhanced osteogenic bioactivities and mechanical properties by incorporating biocompatible magnetic iron oxide nanoparticles(IONPs)and icaritin(ICA).Four types of nano-scaffolds(NS,ICA@NS,NS-IONPs and ICA@NS-IONPs)were *** incorporation of ICA and IONPs minimally impact their surface morphological and chemical *** enhanced the mechanical properties of NS scaffolds,including hardness,tensile strength,and elastic *** vitro assessments demonstrated that ICA@NS-IONPs exhibited enhanced osteogenic bioactivities towards mouse calvarial pre-osteoblast cell line MC3T3-E1 as evidenced by detecting the alkaline phosphatase(ALP)activity level,expressions of osteogenesis-related genes and proteins as well as mineralized nodule *** investigations revealed that MEK/ERK(MAP kinase-ERK kinase(MEK)/extracellularsignal-regulated kinase(ERK))signaling pathway could offer a plausible explanation for the osteogenic differentiation of MC3T3-E1 cells induced by ICA@***,the implantation of nano-scaffolds in rat skull defects exhibited a substantial improvement in in vivo bone ***,IONPs and ICA incorporated coaxial electrospinning nano-scaffolds present a novel strategy for the optimization of scaffolds for bone tissue engineering.

关键词： iron oxide nanoparticles icaritin coaxial electrospinning nano-scaffolds MEK/ERK signaling pathway bone regeneration

3D numerical study of tumor blood perfusion and oxygen transport during vascular normalization

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Applied Mathematics and Mechanics(English Edition) 2015年第2期36卷 153-162页

作者： Jie WU Yan CAI Yi FU Zhujun TAN Ren SUN shixiong xu Zurong DING Cheng DONG Ministry of Education of China(MOE)Key Laboratory of Hydrodynamics Shanghai Jiao Tong University School of Naval Architecture Ocean and Civil EngineeringShanghai Jiao Tong University School of Biological Science and Medical Engineering Southeast University Institute of Biliary Tract Disease Xinhua Hospital Department of Mechanics and Engineering Science Fudan University Department of Biomedical Engineering The Pennsylvania State University

The changes of blood perfusion and oxygen transport in tumors during tumor vascular normalization are studied with 3-dimensional mathematical modeling and numerical simulation. The models of tumor angiogenesis and vascular-disrupting are used to simulate ＂un-normalized＂ and ＂normalized＂ vasculatures. A new model combining tumor hemodynamics and oxygen transport is developed. In this model, the intravasculartransvascular-interstitial flow with red blood cell（RBC） delivery is tightly coupled, and the oxygen resource is produced by heterogeneous distribution of hematocrit from the flow simulation. The results show that both tumor blood perfusion and hematocrit in the vessels increase, and the hypoxia microenvironment in the tumor center is greatly improved during vascular normalization. The total oxygen content inside the tumor tissue increases by about 67%, 51%, and 95% for the three approaches of vascular normalization,respectively. The elevation of oxygen concentration in tumors can improve its metabolic environment, and consequently reduce malignancy of tumor cells. It can also enhance radiation and chemotherapeutics to tumors.

关键词： tumor hypoxia environment oxygen transport red blood cell(RBC) delivery vascular normalization numerical simulation

Lens distortion correction based on one chessboard pattern image

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Frontiers of Optoelectronics 2015年第3期8卷 319-328页

作者： Yubin WU shixiong JIANG Zhenkun xu Song ZHU Danhua CAO School of Optical and Electronic Information Huazhong University of Science and Technology Wuhan 430074 China

This paper proposes a detection method of chessboard comer to correct camera distortions -including radial distortion, decentering distortion and prism distor- tion. This proposed method could achieve high comer detection rate. Then we used iterative procedure to optimize distortion parameter to minimize distortion residual. In this method, first, non-distortion points are evaluated by four points near image center; secondly, Levenberg-Marquardt nonlinear optimization algorithm was adopted to calculate distortion parameters, and then to correct image by these parameters; thirdly, we calculated comer points on the corrected image, and repeated previous two steps until distortion parameters converge. Results showed the proposed method by iterative procedure can make the impact of slight distortion around image center negligible and the average of distortion residual of one line is almost 0.3 pixels.

关键词： computer vision camera distortion distortion correction comer detection

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灰铸铁法兰孔桥开裂后的修复工艺

热加工工艺 2023年第15期52卷 143-145页

作者：徐世雄福建联合石油化工有限公司福建泉州362100

由于灰铸铁材料独特的组织结构,其缺陷焊补难度较大,焊补过程中容易产生裂纹,特别是法兰孔桥处开裂后的现场焊补。焊接熔敷金属容易造成螺栓孔径变小或受堵,无法自由穿入螺栓。通过对焊接裂纹和螺栓孔径变化的原因分析,提出了采用镍基焊... 详细信息

由于灰铸铁材料独特的组织结构,其缺陷焊补难度较大,焊补过程中容易产生裂纹,特别是法兰孔桥处开裂后的现场焊补。焊接熔敷金属容易造成螺栓孔径变小或受堵,无法自由穿入螺栓。通过对焊接裂纹和螺栓孔径变化的原因分析,提出了采用镍基焊材+增焊过渡层和难熔材料预堵塞焊补区域孔洞等满足实际需要的修复工艺,解决了灰铸铁法兰孔桥开裂焊接修复遇到的各种问题,取得了良好的修复效果。

关键词：灰铸铁法兰孔桥开裂修复工艺

Microstructure Characteristics of Interaction Layer of Zn-Al Eutectic Alloy with Al_2O_3p/6061Al Composites

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Journal of Materials Science & Technology 2004年第4期20卷 401-404页

作者： Jiuchun YAN, Zhiwu xu, shixiong LU and Shiqin YANGState Key Laboratory of Advanced Welding Production Technology, Harbin Institute of Technology, Harbin 150001, China Lab. of Adv. Welding Technol. Harbin Inst. of Technol. Harbin 150001 China

The interaction between Zn-AI eutectic alloy and Al203p/6061AI composites in the vacuum furnace was investigated. Great attention has been paid to the elements diffusion, the microstructure and formation of the interface between Zn-AI eutectic alloy and Al2O3p/6061AI composites. Experimental results show that Zn-AI eutectic alloy has a good wetting ability to Al2O3p/6061 Al composites and the wetting angle decreases with increasing the temperature in vacuum. After the interaction, an interaction layer forms between Zn-AI alloy and Al2O3p/6061 Al composites. The phases in the interaction layer mainly consist of α-AI(Zn), Al2O3 and CuZn5 resulted from the diffusion of elements from the Zn-AI alloy. Several porosities distribute in the region near the interface of the Zn-AI alloy/interaction layer. The amount of shrinkage voids in the interacting layer is relevant to the penetration of Zn element into Al2O3p/6061Al composites which is a function of temperature. So it is necessary to lower heating temperature in order to limit the Zn penetration.

关键词： Al2O3p/6061Al composites Zn-Al eutectic alloy Wetting Interface microstructure

Numerical simulation of blood flow and interstitial fluid pressure in solid tumor microcirculation based on tumor-induced angiogenesis

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Acta Mechanica Sinica 2007年第5期23卷 477-483页

作者： Gaiping Zhao Jie Wu shixiong xu M. W. Collins Quan Long Carola S. Konig Yuping Jiang Jian Wang A. R. Padhani Department of Mechanics and Engineering Science Fudan University Shanghai 200433 China Brunel Institute for Bioengineering School of Engineering and Design Brunel University Uxbridge Middlesex UK Department of Neurology Huashan Hospital Fudan University Shanghai 200040 China Paul Strickland Scanner Centre Mount Vernon Hospital Rickmansworth Road Northwood Middlesex HA6 2RN UK

A coupled intravascular-transvascular-interstitial fluid flow model is developed to study the distributions of blood flow and interstitial fluid pressure in solid tumor microcirculation based on a tumor-induced microvascular network. This is generated from a 2D nine-point discrete mathematical model of tumor angiogenesis and contains two parent vessels. Blood flow through the microvascular network and interstitial fluid flow in tumor tissues are performed by the extended Poiseuille＇s law and Darcy＇s law, respectively, transvascular flow is described by Starling＇s law; effects of the vascular permeability and the interstitial hydraulic conductivity are also considered. The simulation results predict the heterogeneous blood supply, interstitial hypertension and low convection on the inside of the tumor, which are consistent with physiological observed facts. These results may provide beneficial information for anti-angiogenesis treatment of tumor and further clinical research.

关键词： Solid tumor pressure-Angiogenesis Blood flow - Interstitial Numerical simulation

Mitosis and microtubule organizational changes in rice root-tip cells

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Cell Research 1993年第1期3卷 93-101页

作者： xu shixiong (SY ZEE), CHUNGUI LI, CHENGZHUBotany Department, Hong Kong University,Department of Biology, Peking University, Beijing100871, China. Botany Department HongKong University Beijing China Department of Biology Peking University Beijing China

The pattern of change of the microtubule cytoskeleton of the root-tip cells of rice during mitosis was studied using immunofiuorescence technic and confocal laser scanning microscopy. All the major stages of cell division including preprophase, prophase, metaphase, anaphase and telophase were observed. The most significant finding was that in the preprophase cells microtubules radiating from the nuclear surface to the cortex were frequently *** development these microtubules became closely associated with the preprophase band and prophase spindle indicating that the microtubules radiating from the nuclear surface, the preprophase band and the prophase spindle were structurally and functionally closely related to each other. Granule-like anchorage sites for the radiating microtubules at the nuclear surface were often seen and the possibility that these granule-like anchorage sites might represent the microtubule organizing centres was discussed.

关键词： microtubule mitosis preprophase root cells Oryza sativa.