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Goblet cell carcinoid of the appendix:Six case reports

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World Journal of Clinical Cases 2024年第22期12卷 5217-5224页

作者： Toshiaki Toshima Ryo Inada shinya Sakamoto Eri Takeda Takahiro Yoshioka Kento Kumon Naoki Mimura Nobuo Takata Motoyasu Tabuchi Kazuyuki Oishi Takuji Sato Kenta Sui Takehiro Okabayashi Kazuhide Ozaki Toshio Nakamura Yuichi Shibuya Manabu Matsumoto Jun Iwata Department of Gastroenterological Surgery Kochi Health Sciences CenterKochi 781-8555Japan Department of Diagnostic Pathology Kochi Health Sciences CenterKochi 781-8555Japan

BACKGROUND Goblet cell carcinoid(GCC)of the appendix is a rare tumor characterized by neuroendocrine and adenocarcinoma *** preoperative diagnosis is very difficult,with most patients complaining mainly of abdominal *** tomography shows swelling of the appendix,so diagnosis is usually made incidentally after appendectomy based on a preoperative diagnosis of *** if a patient undergoes preoperative colonoscopy,accurate endoscopic diagnosis is very difficult because GCC shows a submucosal growth pattern with invasion of the appendiceal *** SUMMARY Between 2017 and 2022,6 patients with GCC were treated in our *** presenting complaint for 5 of these 6 patients was abdominal *** 5 patients underwent appendectomy,including 4 for a preoperative diagnosis of appendicitis and the other for diagnosis and treatment of an appendiceal *** sixth patient presented with vomiting and underwent ileocecal resection for GCC diagnosed from preoperative *** 2 patients with GCC underwent colonoscopy,no neoplastic changes were *** of the six patients showed lymph node metastasis on pathological *** of the last followup(median:15 mo),all cases remained alive without *** As preoperative diagnosis of GCC is difficult,this possibility must be considered during surgical treatments for presumptive appendicitis.

关键词： Goblet cell carcinoid Appendix Preoperative diagnosis Endoscopic diagnosis Surgical treatment Case report

F(R) gravity in the early Universe: electroweak phase transition and chameleon mechanism

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Chinese Physics C 2019年第10期43卷 86-98页

作者： Taishi Katsuragawa shinya Matsuzaki Eibun Senaha Institute of Astrophysics Central China Normal UniversityWuhan 430079China Center for Theoretical Physics and College of Physics Jilin UniversityChangchun130012China Center for Theoretical Physics of the Universe Institute for Basic Science (IBS)Daejeon 34051Korea

It is widely believed that the screening mechanism is an essential feature for the modified gravity theory. Although this mechanism has been examined thoroughly in the past decade, their analyses are based on a conventional fluid prescription for the matter-sector configuration. In this paper, we demonstrate a new formulation of the chameleon mechanism in F(R) gravity theory, to shed light on quantum-field theoretical effects on the chameleon mechanism as well as the related scalaron physics, induced by the matter sector. We show a possibility that the chameleon mechanism is absent in the early Universe based on a scale-invariant-extended scenario beyond the standard model of particle physics, in which a realistic electroweak phase transition, yielding the right amount of baryon asymmetry of Universe today, simultaneously breaks the scale invariance in the early Universe. We also briefly discuss the oscillation of the scalaron field and indirect generation of non-tensorial gravitational waves induced by the electroweak phase transition.

关键词： modified gravity beyond standard model thermal field theory

Improvement in the information-oriented construction of temporary soil-retaining walls using sparse modeling

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Underground Space 2019年第3期4卷 210-224页

作者： Yu Otake Shinnosuke Kodama shinya Watanabe Niigata University Japan

This fundamental study investigates how“super-resolution”technology based on sparse modeling,which has attracted attention in various fields,can be applied to the information-oriented construction of temporary soil-retaining *** machine learning process adopted here is based on the analytical results of numerical computations that involve many preliminary assumptions related to soilretaining walls,rather than the collection of images utilized in the image reconstruction ***,bases for vectors related to the displacement of retaining walls are generated using efficient inverse analysis and“super-resolution”processing from sparse amounts of physical observation *** purpose is to improve the properties of the inverse problem by artificial interpolation based on numerical *** has been shown that the inverse analysis related to the displacement of retaining walls can be performed efficiently and that highly accurate predictions can be achieved even with limited physical *** general,the inverse analysis of retaining walls is an ill-posed ***,if the number of apparent observations reconverted by“super-resolution”technology exceeds the number of unknown parameters,then the displacement distribution of a retaining wall can be estimated *** original idea is to break down the inverse problem into two separate problems by addressing the earth pressure distribution acting on the retaining *** makes it possible to identify the part to which the nonlinear inverse problem can be applied and to facilitate the efficient estimation and interpretation of the results.

关键词： Information-oriented construction Temporary soil-retaining wall Super-resolution Sparse modeling

A method for estimating the errors in many-light rendering with supersampling

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Computational Visual Media 2019年第2期5卷 151-160页

作者： Hirokazu Sakai Kosuke Nabata shinya Yasuaki Kei Iwasaki Wakayama University WakayamaWakayama640-8510Japan Dwango CG Research KADOKAWA Hongo Bldg.5245 HongoBunkyo-kuTokyo1130033Japan

In many-light rendering, a variety of visual and illumination effects, including anti-aliasing,depth of field, volumetric scattering, and subsurface scattering, are combined to create a number of virtual point lights(VPLs). This is done in order to simplify computation of the resulting illumination. Naive approaches that sum the direct illumination from many VPLs are computationally expensive;scalable methods can be computed more efficiently by clustering VPLs, and then estimating their sum by sampling a small number of VPLs. Although significant speed-up has been achieved using scalable methods, clustering leads to uncontrollable errors, resulting in noise in the rendered images. In this paper, we propose a method to improve the estimation accuracy of manylight rendering involving such visual and illumination effects. We demonstrate that our method can improve the estimation accuracy by a factor of 2.3 over the previous method.

关键词： anti-aliasing depth of field many-light rendering participating media

Applying machine learning to market analysis:Knowing your luxury consumer

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Journal of Management Analytics 2019年第4期6卷 404-419页

作者： Kuo Chi-Hsien shinya Nagasawa Department of Commerce Waseda UniversityShinjuku-kuJapan

Chinese consumer research in the luxury sector is the emphasis in the business research ***,it can be cost-intensive or time-consuming to interpret big data from any research conducted in the *** this paper,the researchers created a machine-learning model to help minimize those research *** study analyzed Chinese luxury consumption behavior,while the Chinese contributed 33%of the global luxury market in 2018 and play as a growth engine in the luxury market(Bain&***://***/insights/whats-powering-chinas-market-for-luxury-goods/).The researchers interpreted this analysis using machine-learning algorithms through different sets of conditions and then proposed an understandable and highly accurate machine-learning *** traditional statistical methods,which rely on domain experts to create handcrafted features,this paper proposes an unsupervised end-to-end model that can directly and accurately process questionnaire data without human *** paper also demonstrates how to practically apply an automatic unsupervised analysis method(PCA)to find inferences in the big data,and helps interpret the implied meaning to the questions.

关键词： Luxury consumer machine learning end-to-end model unsupervised learning principal component analysis(PCA)

A Twin Unidirectional Impulse Turbine for Wave Energy Conversion

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Journal of Thermal Science 2011年第5期20卷 394-397页

作者： Manabu Takao Akiyasu Takami shinya Okuhara Toshiaki Setoguchi Matsue College of Technology 14-4 NishiikumaMatsueShimane 690-8518Japan Saga University 1 HonjoSagaSaga 840-8502Japan

A twin unidirectional impulse turbine has been proposed in order to enhance the performance of wave energy plant. This turbine system uses two unidirectional impulse turbines and their flow direction is different from each other. However, the turbine characteristics have not been clarified to date. The performances of a unidirectional impulse turbine under steady flow conditions were investigated experimentaUy by using a wind tunnel with large piston/cylinder in this study. Then, efficiency of the twin impulse turbine have been estimated by a quasi-steady analysis using experimental results.

关键词： Fluid machinery impulse turbine wave energy conversion ocean energy.

Integrated view of plant metabolic defense with particular focus on chewing herbivores

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Journal of Integrative Plant Biology 2022年第2期64卷 449-475页

作者： David Wari Takako Aboshi Tomonori shinya Ivan Galis Institute of Plant Science and Resources Okayama UniversityKurashiki710-0046 Japan Faculty of Agriculture Yamagata UniversityWakaba-machiTsuruoka997-8555 Japan

Success of plants largely depends on their ability to defend against *** emergence of the first voracious consumers,plants maintained adapting their structures and chemistry to escape from *** constant pressure was further accelerated by adaptation of herbivores to plant defenses,which all together sparked the rise of a chemical empire comprised of thousands of specialized metabolites currently found in *** diversity in the plant kingdom is truly amazing,and although many plant metabolites have already been identified,a large number of potentially useful chemicals remain unexplored in plant ***,biosynthetic routes for plant metabolites involve many enzymes,some of which still wait for identification and biochemical ***,regulatory mechanisms that control gene expression and enzyme activities in specialized metabolism of plants are scarcely ***,understanding of how plant defense chemicals exert their toxicity and/or repellency against herbivores remains limited to typical examples,such as proteinase inhibitors,cyanogenic compounds and *** this review,we attempt summarizing the current status quo in metabolic defense of plants that is predominantly based on the survey of ubiquitous examples of plant interactions with chewing herbivores.

关键词： defense herbivore mode of action plant specialized metabolism

Characteristics of glucose change in diabetes mellitus generalized through continuous wavelet transform processing:A preliminary study

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World Journal of Diabetes 2023年第10期14卷 1562-1572页

作者： Yoichi Nakamura shinya Furukawa Cardiovascular Medicine&Diabetology Specified Clinic of Soyokaze CardioVascular Medicine and Diabetes CareMatsuyama 790-0026EhimeJapan Health Services Center Ehime UniversityMatsuyama 790-8577EhimeJapan

BACKGROUND The continuous glucose monitoring(CGM)system has become a popular evaluation tool for glucose fluctuation,providing a detailed description of glucose change *** hypothesized that glucose fluctuations may contain specific information on differences in glucose change between type 1 diabetes mellitus(T1DM)and type 2 diabetes mellitus(T2DM),despite similarities in change patterns,because of different *** Fourier transform,continuous wavelet transform(CWT)is able to simultaneously analyze the time and frequency domains of oscillating *** To investigate whether CWT can detect glucose fluctuations in *** The 60-d and 296-d glucose fluctuation data of patients with T1DM(n=5)and T2DM(n=25)were evaluated *** data obtained every 15 min for 356 d were *** were assessed by CWT with Morlet form(n=7)as the mother *** methodology was employed to search for limited frequency glucose fluctuation in the daily glucose *** frequency and enclosed area(0.02625 scalogram value)of 18 emerged signals were *** specificity for T1DM was evaluated through multiple regression analysis using items that demonstrated significant differences between them as explanatory *** The high frequency at midnight(median:75 Hz,cycle time:19 min)and middle frequency at noon(median:45.5 Hz,cycle time:32 min)were higher in T1DM vs T2DM(median:73 and 44 Hz;P=0.006 and 0.005,respectively).The area of the>100 Hz zone at midnight to forenoon was more frequent and larger in T1DM vs *** a day,the lower frequency zone(15-35 Hz)was more frequent and the area was larger in T2DM than in *** threedimensional scatter diagrams,which consist of the time of day,frequency,and area of each signal after CWT,revealed that high frequency signals belonging to T1DM at midnight had a loose distribution of wave cycles that were 17-24 *** analysis revealed that the high frequency signal at midnight could c

关键词： Continuous glucose monitoring Pathophysiology Fourier,Pseudo-frequency Contour map Scalogram matrix

On-chip 3D rotation of oocyte based on a vibration-induced local whirling flow

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Microsystems & Nanoengineering 2015年第1期1卷 150-158页

作者： Takeshi Hayakawa shinya Sakuma Fumihito Arai Department of Micro-Nano Systems Engineering Nagoya UniversityNagoya-CityAichi-Pref.JAPAN

We propose a novel on-chip 3D cell rotation method based on a vibration-induced *** circular vibration is applied to a microchip with micropillar patterns,a highly localized whirling flow is induced around the *** direction and velocity of this flow can be controlled by changing the direction and amplitude of the applied ***,this flow can be induced on an open chip *** this study,we adopted a microchip with three micropillars arranged in a triangular configuration and an xyz piezoelectric actuator to apply the circular *** the centre of the micropillars,the interference of the vibration-induced flows originating from the individual micropillars induces rotational ***,a biological cell placed at this centre rotates under the influence of the *** three-plane circular vibrations in the xy,xz or yz plane,the cell can rotate in both the focal and vertical planes of the *** this 3D cell rotation method,we measured the rotational speeds of mouse oocytes in the focal and vertical planes as 63.7±4.0°s^(−1) and 3.5±2.1°s^(−1),***,we demonstrated the transportation and rotation of the mouse oocytes and re-positioned their nuclei into a position observable by microscope.

关键词： lab on a chip cell manipulation vibration-induced flow acoustic streaming