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Advances in endoscopic diagnosis and management of colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第10期16卷 4045-4051页

作者： shi-wei li Xiang liu Si-Yu Sun Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Engineering Research Center of Ministry of Education for Minimally Invasive Gastrointestinal Endoscopic Techniques Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

Colorectal cancer(CRC)is a leading global health concern,and early identification and precise prognosis play a vital role in enhancing patient *** is a minimally invasive imaging technique that is crucial for the screening,diagnosis,and treatment of *** editorial discusses the importance of advances in endoscopic techniques,the integration of artificial intelligence,and the potential of novel technologies in enhancing the diagnosis and management of CRC.

关键词： Colorectal cancer Endoscopic diagnosis Endoscopic management Artificial intelligence Endoscopic devices

Multi-site Passivation of ZnO Metal Oxides via Biomolecules for Efficient and Highly Stable Organic Solar Cells

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Chinese Journal of Chemistry 2024年第14期42卷 1582-1592页

作者： Irfan Ismail Maria Khalil Xiaomei Gao Xingze Chen Muhammad Jawad Rong Huang Zhiyun li Emmanuel Acheampong Tsiwah wei-shi li Qun Luo Chang-Qi Ma i-Lab&Printable Electronics Research Center Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO)Chinese Academy of Sciences(CAS)SuzhouJiangsu215123 China University of Chinese Academy of Sciences(UCAS) Beijing100040 China School of Nano-Tech and Nano-Bionics University of Science and Technology of China(USTC)HefeiAnhui230027 China Shanghai Institute of Organic Chemistry(SIOC) Chinese Academy of Sciences(CAS)Shanghai200032 China Vacuum Interconnected Nanotech Workstation(Nano-X) SuzhouJiangsu215123 China

ZnO nanoparticles(nps)among metal oxide(MOs)are proven to be essential electron transporting layers(ETLs)applied in organic solar cells(OSCs).However,intrinsic defects,interfacial charge recombination,and catalytic behavior towards the active layer restrict the applications of ZnO nps for efficient and long-term stable *** commonly available biomolecule cytidine 5'-monophosphate(CMP-OH)with phosphonic acid,its salt cytidine 5'-monophosphate disodium salt(CMP-ONa)with a phosphate group as an anchoring group and conjugated terminal functional in both analogous molecules provide carrier transfer bridge at bottom interface of the active *** theoretical investigations and characterizations have discovered the multi-site coordination of CMP-OH towards acceptor molecules and ZnO *** dual-side alignment of CMP analogous molecules hinders interfacial charge recombination and enhances charge transfer potential at ***,PM6:L8-BO-based OSCs with modified ETL obtain 18.13%efficiency,12%higher than that of unmodified *** higher efficiency,CMP-OH-based OSC devices illustrate remarkably improved thermal stability for 500 h at 85℃with 72%of initial PCE and operation stability for 2000 h with 90.1%of initial *** work reveals the passivation mechanism of multi-anchoring groups towards MOs and single-functional groups towards the active layer to optimize the interface for efficient and highly stable OSCs.

关键词： Organic solar cells Nanoparticles Nucleotides Interfacial interactions Surface chemistry Multi-site passivation

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偏振调制扫描光学显微镜方法

物理学报 2024年第15期73卷 187-195页

作者：张洋张志豪王宇剑薛晓兰陈令修石礼伟中国矿业大学材料与物理学院徐州221116

基于反射差分谱原理搭建了适用于二维材料和微纳器件的偏振调制扫描光学显微镜系统,可以实现对于材料或者器件的微米级区域进行反射差分显微成像的研究.通过研究两种典型的二维层状材料MoS_(2)和ReSe_(2)的反射差分显微成像,发现相比于... 详细信息

基于反射差分谱原理搭建了适用于二维材料和微纳器件的偏振调制扫描光学显微镜系统,可以实现对于材料或者器件的微米级区域进行反射差分显微成像的研究.通过研究两种典型的二维层状材料MoS_(2)和ReSe_(2)的反射差分显微成像,发现相比于传统的反射显微镜,我们搭建的偏振调制扫描光学显微镜对于二维材料的层数特征更敏感,且可以用来表征二维材料的平面光学各向异性.相关研究有助于更进一步理解层状二维材料的层数特征和各向异性性质.

关键词：反射各向异性光谱显微成像光学各向异性二维材料

三项炎症因子(CRP、PCT和IL-6)联合红细胞分布宽度与血小板计数比值在早期冠心病诊断中的价值研究

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罕少疾病杂志 2024年第6期31卷 114-116页

作者：石立威赵贺红开封市人民医院检验科河南开封475000

目的研究三项炎症因子(CRP、PCT和IL-6)联合红细胞分布宽度与血小板计数比值在早期冠心病(CHD)诊断中的价值。方法选取2020年3月-2022年3月于我院就诊的早期CHD患者98例纳入CHD组,选取同期于我院行体检的健康志愿者98例纳入健康组作... 详细信息

目的研究三项炎症因子(CRP、PCT和IL-6)联合红细胞分布宽度与血小板计数比值在早期冠心病(CHD)诊断中的价值。方法选取2020年3月-2022年3月于我院就诊的早期CHD患者98例纳入CHD组,选取同期于我院行体检的健康志愿者98例纳入健康组作为对比,分别测定两组患者C反应蛋白(CRP)、降钙素原(PCT)、白细胞介素-6(IL-6)、红细胞分布宽度(RDW)和血小板计数(PLT),计算出RDW和PLT比值(RPR),对比三项炎症因子(CRP、PCT、IL-6)诊断与RPR进行早期CHD联合诊断与单一诊断的价值。结果 CHD组CRP、IL-6、PCT、RDW和RPR水平高于健康组,PLT水平更低(P<0.05)。三项炎症因子(CRP、IL-6、PCT)对CHD的诊断敏感度为80.61%,特异度为70.41%;RPR诊断的敏感度为81.63%,特异度为79.59%;三项炎症指标联合RPR诊断敏感度为92.86%,特异度为91.84%,高于单一诊断结果(P<0.05)。结论采用三项炎症因子(CRP、IL-6、PCT)联合RPR对早期CHD进行诊断,具有较高的诊断价值,对于早期疾病筛查有一定意义,值得临床广泛应用。

关键词：早期冠心病三项炎症因子红细胞分布宽度血小板计数诊断价值

世界文化遗产视域下土司金石文献的内容、特征及当代价值

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遵义师范学院学报 2024年第5期26卷 11-15,19页

作者：石伟丽李鸿雁瞿州莲吉首大学师范学院湖南吉首416000 吉首大学图书馆湖南吉首416000 吉首大学人文学院湖南吉首416000

世界文化遗产土司金石文献包括记述人物生平事迹、反映土司日常生活及思想状况、反映战事、表彰战功等主要内容,具有稀缺性、多样性、历史性、民族性、艺术性特征以及教育、学术、政治、经济、文化等方面的当代价值。

关键词：世界文化遗产土司金石文献价值

High-performance Refractive Index Sensor Based on Photonic Crystal Single Mode Resonant Micro-cavity

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稀有金属材料与工程 2006年第A3期35卷 425-428页

作者： Shengye Huang Junfeng shi Dongsheng Wang wei li State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision Instruments and Mechanology Tsinghua University Beijing 100084 China

An effective refractive index sensor built with square lattice photonic crystal is proposed,which can be applicable to photonic integrated *** photonic crystal waveguides rather than conventional ridge waveguides are used as entrance/exit waveguides to the *** layers of photonic lattice are set between the photonic crystal waveguides and the micro-cavity to achieve both a high transmission and a high *** plane wave method is utilized to calculate the disperse curves and the finite difference time domain scheme is employed to simulate the light *** the resonant wavelength of about 1500 nm,the resonant wavelength shifts up by 0.7 nm for each increment of Δn=0.001.A transmission of more than 0.75 is *** the position disorder of the photonic crystal doesn't affect the sensitivity of the sensor, the transmission reduces rapidly as the disorder increases.

关键词： optical biosensor refractive index sensor photonic crystal resonant cavity

Protein-protein Interaction Between Domains of PDZ and BAR from PICK1

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Chemical Research in Chinese Universities 2007年第2期23卷 191-195页

作者： XIAO Hong shi Ya-wei WANG li-li YUAN Jing-ming Institute of Biotechnology Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education Shanxi University Taiyuan 030006 P. R. China

Two DNA fragments encoding PDZ domain （21-110 residues） and BAR domain （ 150-360 residues） from PICK1 （1-416 residues） were amplified by PCR and then introduced into vectors, pET-32M and pMAL-e2X respectively to generate recombinant plasmids, pE-pdz and pM-bar. Having been separately transferred into the hosts E. coli BL21 and E. coli JM109, these two strains can express fusion proteins： His-tagged PDZ（PDZ domain） and maltose binding protein-BAR（ MBP-BAR domain） respectively, as confirmed by both SDS-PAGE and Wostem blotting. The interaction between these two domains is dose-dependence, as identified by a pull-down test. Moreover, it has been shown from the EliSA analysis that the actual amount of PDZ bound to MBP-BAR-amylose beads reaches （ 16 ± 0. 5）%, as calculated by the molar ratio of PDZ to MBP-BAR. In addition, the interaction between BAR（bait） and PDZ（prey） in vivo was also examined with a yeast two-hybrid system.

关键词： BAR domain PDZ domain PICK1 Protein-protein interaction Pull-down test Yeast two-hybrid

Changing to Poly（rod-coil） Polymers： A Promising Way for an Optoelectronic Compound to Improve Its Film Formation

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Chinese Journal of Chemistry 2015年第8期33卷 847-851页

作者： wei Shao Long liang Xuan Xiang Hong-Jiao li Fu-Gang Zhao wei-shi li Department of Chemistry Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Education Ministry Zhejiang Sci- Tech University Hangzhou Zhejiang 310018 China Key Laboratory of Synthetic and Self-assembly Chemistry for Organic Functional Molecules Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China

Good film formation is one of basic requirements for organic optoelectronic materials to achieve the capability for fabrication of large area devices. Small molecular optoelectronic compounds have a definite chemical structure and clear device performance, and thus are welcomed in the field. However, they are generally suffering from poor film formation, especially in a large area. For addressing it, this contribution proposes and demonstrates a strategy, that is, changing them into poly（rod-coil） polymers. With one optoelectronic compound [BDT（DTBT）2] and three poly（rod-coil） polymers （P1, P2, and P3） having different non-conjugated coil segments as examples, the work clearly shows that the change to poly（rod-coil） polymers keeps many basic optoelectronic properties of the refer- ence compound, including light absorption in solution, bandgap and frontier orbital energy levels, but suppresses strong intermolecular interactions and crystalline structure in film state. Further comparisons on film formation quality on glass and ITO glass illustrate that all the three polymers have a better film formation property than the reference compound.

关键词： organic optoelectronic materials poly(rod-coil) polymers film formation

Pressure-Induced Anomalous Phase Transitions and Colossal Enhancements of Piezoelectricity in Ground-State BaTi0_(3)

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Chinese Physics Letters 2011年第4期28卷 156-159页

作者： DUAN Yi-Feng QIN li-Xia shi li-wei TANG Gang Department of Physics China University of Mining and TechnologyXuzhou 221116

Rhombohedral BaTi0_(3)under hydrostatic pressure is investigated by first principles *** results show that just like tetragonal perovskites,as pressure increases,this material first becomes para-electric at low pressures,then transfers to another ferroelectric phase at much higher *** also find a giant enhancement of piezoelectricity near the phase-transition regions,due to large atomic displacements along different directions in response to the applied pressures.

关键词： Transition directions ferroelectric