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Interplay of RNA-binding proteins controls germ cell development in zebrafish

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Journal of Genetics and Genomics 2024年第9期51卷 889-899页

作者： De-li shi Laboratory of Developmental Biology CNRS-UMR7622Institut de Biologie Paris-Seine(IBPS)Sorbonne University75005 ParisFrance

The specification of germ cells in zebrafish mostly relies on an inherited mechanism by which localized maternal determinants,called germ plasm,confer germline fate in the early *** studies have partially allowed the identification of key regulators governing germ plasm formation and subsequent germ cell ***-binding proteins,acting in concert with other germ plasm components,play essential roles in the organization of the germ plasm and the specification,migration,maintenance,and differentiation of primordial germ *** loss of their functions impairs germ cell formation and causes sterility or sexual *** is emerging that they instruct germline development through differential regulation of mRNA fates in somatic and germ ***,the challenge remains to decipher the complex interplay of maternal germ plasm components in germ plasm compartmentalization and germ cell *** failure to control the developmental outcome of germ cells disrupts the formation of gametes,it is important to gain a complete picture of regulatory mechanisms operating in the germ cell *** review sheds light on the contributions of RNA-binding proteins to germ cell development in zebrafish and highlights intriguing questions that remain open for future investigation.

关键词： Germplasm Primordialgerm cell Germlinestem cell Gametogenesis Zebrafish RNA-binding protein Posttranscriptional gene expression Translational activation and repression

Matrix orthogonal polynomials,non-abelian Toda lattices,and Bäcklund transformations

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Science China Mathematics 2024年第9期67卷 2071-2090页

作者： shi-Hao li Department of Mathematics Sichuan UniversityChengdu 610064China

A connection between matrix orthogonal polynomials and non-abelian integrable lattices is investigated in this *** normalization factors of matrix orthogonal polynomials expressed using quasideterminants are shown to be the solutions to the non-abelian Toda lattice in semi-discrete and full-discrete ***,with a moment modification method,we demonstrate that the B¨acklund transformation of the non-abelian Toda lattice given by Popowicz(1983)is equivalent to the non-abelian Volterra lattice,whose solutions can be expressed using quasi-determinants as well.

关键词： matrix orthogonal polynomial non-abelian Toda lattice Backlund transformation quasideterminant technique

Constructing the Impossible Differential of Type-II GFN with Boolean Function and Its Application to WARP

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Chinese Journal of Electronics 2024年第1期33卷 80-89页

作者： Jiali shi Guoqiang liU Chao li College of liberal Arts and Sciences National University of Defense Technology Hunan Engineering Research Center of Commercial Cryptography Theory and Technology Innovation State Key Laboratory of Information Security Institute of Information Engineering

Type-Ⅱ generalized Feist el network(GFN) has attracted a lot of attention for its simplicity and high *** differential attack is one of the powerful cryptanalytic approaches for word-oriented block ciphers such as Feistel-like *** deduce the impossible differential of Type-Ⅱ GFN by analyzing the Boolean function in the middle *** main idea is to investigate the expression with the variable representing the plaintext(ciphertext) difference words for the internal state *** adopting the miss-in-the-middle approach,we can construct the impossible differential of Type-Ⅱ *** an illustration,we apply this approach to WARP,a lightweight 128-bit block cipher with a 128-bit key which was presented by Banik et *** SAC *** structure of WARP is a 32-branch Type-Ⅱ ***,we find two 21-round truncated impossible differentials and implement a 32-round key recovery attack on *** the 32-round key recovery attack on WARP,some observations are used to mount an effective *** the advantage of the early abort technique,the data,time,and memory complexities are 2125.69chosen plaintexts,2126.6832-round encryptions,and 2100-bit,*** the best of our knowledge,this is the best attack on WARP in the single-key scenario.

关键词： Ciphers Boolean functions Parallel processing Complexity theory

On Isodual Double Toeplitz Codes

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Journal of Systems Science & Complexity 2024年第5期37卷 2196-2206页

作者： shi Minjia XU li SOLéPatrick Key Laboratory of Intelligent Computing and Signal Processing Ministry of EducationSchool of Mathematical SciencesAnhui UniversityHefei 230601China State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of SciencesBeijing 100093China CNRS University of Aix MarseilleCentrale MarseilleI2MMarseille 13284France

Double Toeplitz(shortly DT)codes are introduced here as a generalization of double circulant *** authors show that such a code is isodual,hence formally self-dual(FSD).FSD codes form a far-reaching generalization of self-dual codes,the most important class of codes of rate ***-dual DT codes are characterized as double circulant or double ***,even binary DT codes are characterized as double *** examples obtained by exhaustive search show that the codes constructed have best-known minimum distance,up to one unit,amongst formally self-dual codes,and sometimes improve on the known *** q=2,the authors find four improvements on the best-known values of the minimum distance of FSD *** F4 an explicit construction of DT codes,based on quadratic residues in a prime field,performs equally *** authors show that DT codes are asymptotically good over ***,the authors construct DT codes arbitrarily close to the asymptotic Varshamov-Gilbert bound for codes of rate one half.

关键词： Double circulant codes double Toeplitz codes isodual codes formally self-dual codes

Rhodium-catalyzed addition reactions of benzylic C–H bonds to cyclic N-sulfonyl ketimines viaπ-coordination

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Chinese Chemical Letters 2024年第3期35卷 287-291页

作者： Yuntong li Hang shi Department of Chemistry Zhejiang UniversityHangzhou 310027China Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province Department of ChemistrySchool of Science and Research Center for Industries of the FutureWestlake UniversityHangzhou 310030China Institute of Natural Sciences Westlake Institute for Advanced StudyHangzhou 310024China

Mannich-type reactions are a widely used method for the synthesis of amines due to the readily availability of nucleophiles and ***,the inclusion of alkylarenes instead of active carbon pronucleophiles such as aldehydes and ketones in these addition reactions has been a challenge due to the inherent difficulty of benzylic *** this study,we present a novel approach for the construction of N-sulfonyl amines via rhodium-catalyzed addition of unbiased benzylic C–H bonds to cyclic N-sulfonyl ketamines throughπ-*** strategy enables the synthesis of a diverse range of N-sulfonyl amines,and subsequent diversification of the addition products showcases the synthetic potential of this protocol.

关键词： Benzylic deprotonation Cyclic N–sulfonyl ketimines π-Coordination Mannich-type addition Rhodium catalysis

Theory and test of underground explosions:Coupling rule between cratering and ground shock

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Underground Space 2024年第4期17卷 146-160页

作者： Wei Guo Jie li Benjun shi Tianhan Xu Xiaohui Xu Gan li Jie shi State Key Laboratory of Disaster Prevention and Mitigation of Explosion and Impact Army Engineering University of PLANanjing 210007China

Calculating the parameters of the ground shock induced by an underground explosion is a complex energy coupling *** is difficult to establish a unified ground shock coupling law from limited test *** paper summarizes the research results obtained at home and abroad and systematically analyzes the coupling mechanism of craters formed by an underground explosion and the ground *** differences between the concepts of"closed-explosion critical depth"and"equivalent closed-explosion critical depth"are clearly *** spreading of the ground shock energy is attributed to the explosive expansion of the air cavity,revealing a linear relationship between the volume of the cavity region(or the volume of the crack region)and the ground shock energy associated with the underground *** proportionality factor is related to the mechanical properties of the medium and is independent of the magnitude of the explosion *** on this,a theoretical calculation formula and conversion method for the ground shock coupling coefficient were *** tests were conducted in clay and Plexiglass under varying burial *** test results were consistent with the theoretically calculated *** study provides a theoretical basis for the design of explosion-resistant structures in underground engineering.

关键词： Underground explosion Ground shock coupling Coupling coefficient Equivalent closed explosion Experimental study

Physiological and pathological functions of circular RNAs in the nervous system

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Neural Regeneration Research 2024年第2期19卷 342-349页

作者： Min Zhou shi li Chuan Huang School of life Sciences Chongqing UniversityChongqingChina

Circular RNAs(circRNAs)are a class of covalently closed single-stranded RNAs that are expressed during the development of specific cells and *** play crucial roles in physiological and pathological processes by sponging microRNAs,modulating gene transcription,controlling the activity of certain RNA-binding proteins,and producing functional peptides.A key focus of research at present is the functionality of circRNAs in the nervous system and several advances have emerged over the last 2 ***,the precise role of circRNAs in the nervous system has yet to be comprehensively *** this review,we first summarize the recently described roles of circRNAs in brain development,maturity,and ***,we focus on the involvement of circRNAs in various diseases of the central nervous system,such as brain cancer,chronic neurodegenerative diseases,acute injuries of the nervous system,and neuropathic pain.A better understanding of the functionality of circRNAs will help us to develop potential diagnostic,prognostic,and therapeutic strategies to treat diseases of the nervous system.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis brain development circRNAs neuropathic pain Parkinson’s disease

Supercritical CO_(2) Cycles for Nuclear-Powered Marine Propulsion:Preliminary Conceptual Design and Off-Design Performance Assessment

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Journal of Thermal Science 2024年第1期33卷 328-347页

作者： li Zhaozhi shi Mingzhu SHAO Yingjuan ZHONG Wenqi Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education School of Energy and EnvironmentSoutheast UniversityNanjing 210096China

Using the efficient,space-saving,and flexible supercritical carbon dioxide(sCO_(2)) Brayton cycle is a promising approach for improving the performance of nuclear-powered *** purpose of this paper is to design and compare sCO_(2) cycle power systems suitable for nuclear-powered *** the characteristics of nuclear-powered ships,this paper uses different indicators to comprehensively evaluate the efficiency,cost,volume,and partial load performance of several nuclear-powered sCO_(2) *** load-following strategies are also designed and *** results show that the partial cooling cycle is most suitable for nuclear-powered ships because it offers both high thermal efficiency and low volume and cost,and can maintain relatively high thermal efficiency at partial ***,the new load-following strategy that adjusts the turbine speed can keep the compressor away from the surge line,making the cycle more flexible and efficient compared to traditional inventory and turbine bypass strategies.

关键词： supercritical CO_(2)cycle nuclear marine propulsion off-design performance

Interface structure of α-Mg/14H-LPSO:First-principles prediction and experimental study

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Journal of Rare Earths 2024年第9期42卷 1792-1799,I0006页

作者： Yuan shi Xiaohua Zhang Hongyan Yue Chao li School of Materials Science and Chemical Engineering Harbin University of Science and TechnologyHarbin150040China

The interfacial structure of the α-Mg/14H-LPSO phase in rare earth-including magnesium alloy was investigated via high-angle annular dark-field scanning transmission electron microscopy(HAADFSTEM) imaging and first-principles calculations of density-functional *** possible interfacial models were constructed according to the different terminations of the LPSO phase,and the corresponding interfacial energies were calculated,from which the four most stable structures(Terl-MgY-hollow,Ter2-Zn-hollow,Ter3-MgYII-hollow and Ter4-Mg-bridge) were *** interfacial phase diagrams related to the Y chemical potentials were obtained from the calculations,and the most stable interfacial structure was ***-MgY-hollow and Ter2-Zn-hollow have the lowest interfacial energies in the range of-0.7 eV <Δμγ<-0.6 eV,where fluctuating change of state is the minimized and the interface is the most *** separation work of the two models was calculated to predict the bonding strength of the structures at both ends of the *** calculation results show that the maximum interfacial separation work is 1.45 J/m^(2) for the interface model of α-Mg and 14H-LPSO phase structure with Ter2-Zn-hollow termination.

关键词： Rare earths Magnesium alloy HAADF-STEM LPSO First-principles Interface