检索结果-南通市图书馆

Clinical characteristics and outcomes of psoriasis patients with COVID-19: A retrospective, multicenter cohort study in China

引用

中华医学杂志(英文版) 2024年第14期137卷 1736-1743页

作者： Liu Yanhua Xu Zhongrui Zhou Jian Chen Aijun Zhang Junling Kang Xiaojing Jiang Xian Lyu Chengzhi shi Chunrui shi yuling Liu Xiaoming Li Fuqiu Yang Bin Huang Yongmei Yu Chen Wang Gang Department of Dermatology Xijing Hospital Fourth Military Medical University Xi’an Shaanxi China Department of Dermatology The First Affiliated Hospital of Chongqing Medical University Chongqing China Department of Dermatology Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital Tianjin China Department of Dermatology and Venereology People’s Hospital of Xinjiang Uygur Autonomous Region Urumqi Xinjiang China Department of Dermatology West China Hospital Sichuan University Chengdu Sichuan China Department of Psoriasis Dalian Dermatosis Hospital Dalian Liaoning China Department of Dermatology The First Hospital of Lanzhou University Lanzhou Gansu China Skin Disease Hospital of Tongji University Shanghai China Department of Dermatology The University of Hong Kong-Shenzhen Hospital Shenzhen Guangdong China Department of Dermatology The Second Hospital of Jilin University Changchun Jilin China Department of Dermatology Dermatology Hospital of Southern Medical University Guangzhou Guangdong China Department of Dermatology Xining First People’s Hospital Xining Qinghai China

Background: Limited information exists regarding the impact of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection on psoriasis patients. The objective of this study was to identify clinical factors associated with the prognosis of psoriasis following SARS-CoV-2 ***: A retrospective, multicenter study was conducted between March and May 2023. Univariable and multivariable logistic regression analyses were employed to identify factors associated with coronavirus disease 2019 (COVID-19)-related psoriasis outcomes. The study included 2371 psoriasis patients from 12 clinical centers, with 2049 of them having been infected with ***: Among the infected groups, lower exacerbation rates were observed in individuals treated with biologics compared to those receiving traditional systemic or nonsystemic treatments (22.3% [236/1058]vs. 39.8% [92/231]vs. 37.5% [140/373],P <0.001). Psoriasis progression with lesions (adjusted odds ratio [OR] = 8.197, 95% confidence interval [95% CI] = 5.685–11.820, compared to no lesions), hypertension (adjusted OR = 1.582, 95% CI = 1.068–2.343), traditional systemic (adjusted OR = 1.887, 95% CI= 1.263–2.818), and nonsystemic treatment (adjusted OR= 1.602, 95% CI= 1.117–2.297) were found to be associated with exacerbation of psoriasis after SARS-CoV-2 infection, but not biologics (adjusted OR = 0.931, 95% CI = 0.680–1.274, compared to no treatment), according to multivariable logistic regression ***: A reduced risk of psoriasis exacerbation after SARS-CoV-2 infection was observed with biologics compared to traditional systemic and nonsystemic treatments. Significant risk factors for exacerbation after infection were identified as existing psoriatic lesions and hypertension.

关键词： COVID-19 SARS-CoV-2 Psoriasis Treatment Biologics

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese expert consensus on the diagnosis and treatment of balanoposthitis

引用

Chinese Medical Journal 2024年第13期137卷 1519-1521页

作者： Li Zhang Amer A.A.Abdulrahman Hao Guo Jia’an Zhang Xinghua Gao Weihua Pan Gang Wang Jinhua Xu yuling shi Liuqing Chen Hongxiang Chen Songmei Geng Yuping Ran Hongwei Wang Xiaoyong Man Jianmin Chang Furen Zhang Litao Zhang Guangwen Yin Jianzhong Zhang Wei Lai Zhibin Niu Hongkun Jiang Haibo Liu Yaolong Chen Jianjian Wang Department of Dermatology The First Hospital of China Medical UniversityShenyangLiaoning 110001China Key Laboratory of Immunodermatology Ministry of Education and NHCNational Joint Engineering Research Center for Theranostics of Immunological Skin DiseasesShenyangLiaoning 110001China Department of Dermatology Chinese Academy of Medical Science and Peking Union Medical CollegeNanjingJiangsu 210042China Department of Dermatology Second Affiliated Hospital of Naval Medical UniversityShanghai 200003China Department of Dermatology Xijing HospitalFourth Military Medical UniversityXi’anShaanxi 710032China Department of Dermatology Huashan HospitalFudan UniversityShanghai 200040China Department of Dermatology Shanghai Skin Disease HospitalTongji University School of MedicineShanghai 200443China Department of Dermatology Wuhan No.1 HospitalWuhanHubei 430022China Department of Dermatology Huazhong University of Science and Technology Union Shenzhen HospitalShenzhenGuangdong 518052China Department of Dermatology Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710004China Department of Dermatovenereology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Dermatology Huadong HospitalFudan UniversityShanghai 200040China Department of Dermatology Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310009China Department of Dermatology Beijing HospitalBeijing 100730China Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and Venereology Shandong First Medical University&Shandong Academy of Medical SciencesJinanShandong 250061China Department of Dermatology Tianjin Academy of Traditional Chinese Medicine Affiliated HospitalTianjin 300120China Department of Dermatology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Dermatology Peking University People’s HospitalBeijing 100044 China Department of Dermatology Third Affi

Balanoposthitis(BP),a common male genitalia inflammation,is managed by clinicians from different specialties,including urology,pediatrics,dermatology,and *** to this diverse array of clinicians involved,there exists a lack of consistent,evidence-based recommendations for *** development of the consensus engaged 19 representative hospitals and it adhered to rigorous protocols,encompassing international registration(IPGRP-2021CN003)and the application of evidence grading criteria and recommendation standards[Appendix S1,Supplementary File,http://***/CM9/C42].Over the period from December 2020 to October 2022,consensus on 12 clinical issues was reached through comprehensive evidence searches and two iterations of Delphi surveys[Supplementary File,http://***/CM9/C42].

关键词： Delphi diagnosis rigorous

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

消费降级情况下国产鞋类品牌的营销策略调整

引用

中国皮革 2024年第8期53卷 65-68页

作者：史雨灵西安培华学院会计与金融学院陕西西安710125

消费降级是指消费者在购买商品或服务时,倾向于选择价格更低、性价比更高的产品,而不是追求高价、奢侈品。近年来,这种现象逐渐显现。消费降级导致消费者对鞋类产品的需求发生变化,更加注重产品的性价比和实用性。因此,国产鞋类品牌需... 详细信息

消费降级是指消费者在购买商品或服务时,倾向于选择价格更低、性价比更高的产品,而不是追求高价、奢侈品。近年来,这种现象逐渐显现。消费降级导致消费者对鞋类产品的需求发生变化,更加注重产品的性价比和实用性。因此,国产鞋类品牌需要调整产品策略,推出更符合消费者需求的产品。本文研究了消费降级的概念、影响,以及营销策略的相关理论,提出了国产鞋类品牌在营销策略上的调整方案,为其他国产鞋类品牌提供借鉴。

关键词：消费降级鞋类品牌营销策略

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

五运六气指导司天方和龙砂开阖六气针法并用治疗失眠的临床研究

引用

光明中医 2024年第14期39卷 2842-2846页

作者：石玉玲珠海市人民医院医疗集团高新医院/珠海高新技术产业开发区人民医院中医科

目的观察五运六气指导司天方和龙砂开阖六气针法并用治疗失眠的效果。方法将60例失眠患者随机分为司天方组、司天方+龙砂开阖六气针法组、对照组，每组20例。共治疗4周。通过统计不同时点PSQI评分量表、总有效率，整体评价临床疗效。... 详细信息

目的观察五运六气指导司天方和龙砂开阖六气针法并用治疗失眠的效果。方法将60例失眠患者随机分为司天方组、司天方+龙砂开阖六气针法组、对照组，每组20例。共治疗4周。通过统计不同时点PSQI评分量表、总有效率，整体评价临床疗效。结果司天方+龙砂开阖六气针法组治疗1 d后PSQI评分明显低于司天方组、对照组(P<0.05),司天方组、司天方+龙砂开阖六气针法组治疗4周后及随访4周后PSQI得分均明显低于对照组(P<0.05),司天方组、司天方+龙砂开阖六气针法组治疗4周后及随访4周后总有效率均明显高于对照组(P<0.05),3组均未见严重不良反应。结论五运六气指导司天方和龙砂开阖六气针法并用治疗失眠起效快，临床疗效好，远期疗效稳定。

关键词：不寐失眠五运六气司天方龙砂开阖六气针法

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

基于损伤耦合演化过程的黏土-结构物界面统计损伤本构模型

引用

中南大学学报（自然科学版） 2024年第6期55卷 2260-2272页

作者：李怀鑫晏长根石玉玲余柄学梅颢鹏长安大学公路学院陕西西安710064 长安大学地质工程与测绘学院陕西西安710054 江苏地质矿产设计研究院(中国煤炭地质总局检测中心) 江苏徐州221006

为了评估粗糙度对土与结构物界面强度特性的影响,首先,开展不同法向应力条件下黏土和不同粗糙度黏土-结构物界面强度的直剪试验,分析了土体剪切面强度和界面强度的相互关系;其次,利用图像处理软件分析黏土-结构物界面的剪切机理,提出了... 详细信息

为了评估粗糙度对土与结构物界面强度特性的影响,首先,开展不同法向应力条件下黏土和不同粗糙度黏土-结构物界面强度的直剪试验,分析了土体剪切面强度和界面强度的相互关系;其次,利用图像处理软件分析黏土-结构物界面的剪切机理,提出了考虑结构物表面粗糙度影响的界面损伤耦合演化过程;第三,引入考虑界面粗糙度影响的等效初始损伤因子,基于连续损伤理论和统计强度理论建立了考虑界面损伤耦合演化过程的黏土-结构物界面统计损伤本构模型;最后,结合室内试验结果验证了模型适用性。研究结果表明:在相同法向应力条件下,界面粗糙度越大,界面强度越接近土体强度;界面强度与结构物表面粗糙度呈幂函数关系增加,其增长速率随结构物表面粗糙度增加而降低;黏土-结构物界面剪切全过程的损伤演化过程可分为等效初始损伤阶段和加载损伤阶段,其中,等效初始损伤阶段受界面粗糙度影响,加载损伤包括受荷损伤和耦合损伤。本文模型所得结果与试验结果的吻合度较高,能较好地反映黏土与结构物界面损伤本构特征。

关键词：土与结构物界面粗糙度等效初始损伤因子损伤耦合演化统计损伤理论本构模型

来源：

维普期刊数据库

同方期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

珠江口盆地油气勘探新领域及资源潜力

引用

石油学报 2024年第1期45卷 183-201页

作者：高阳东刘军彭光荣陈林王梓颐史玉玲中国海洋石油有限公司勘探开发部北京100010 中海石油(中国)有限公司深圳分公司广东深圳518054 中海石油深海开发有限公司广东深圳518054 中海石油(中国)有限公司湛江分公司广东湛江524057

珠江口盆地油气勘探尚处于中、低勘探程度阶段,近年来,盆地加大了新领域的研究与评价力度,取得了一系列勘探成果。在富烃洼陷文昌A凹、陆丰凹陷、惠州凹陷、番禺4洼的古近系,富烃洼陷惠州凹陷的古潜山,新洼陷阳江东凹与开平凹陷等实现... 详细信息

珠江口盆地油气勘探尚处于中、低勘探程度阶段,近年来,盆地加大了新领域的研究与评价力度,取得了一系列勘探成果。在富烃洼陷文昌A凹、陆丰凹陷、惠州凹陷、番禺4洼的古近系,富烃洼陷惠州凹陷的古潜山,新洼陷阳江东凹与开平凹陷等实现了多领域、多类型勘探新发现,落实了规模储量,为南海东、西部油田稳定发展夯实了储量基础。明确断陷盆地的大型增压型断裂转换斜坡带是大中型油气田勘探的主要方向,打破了文昌A凹多年未有规模发现的局面;创新提出"早断输导、小型源-汇体系及转换带控砂,洼间隆控藏"成藏认识,指导了陆丰南古近系高产能油田群的发现;建立扇三角洲—辫状河三角洲沉积体系勘探技术系列,推动了惠西南古近系陡坡带亿吨级油田群的发现;深化富砂层系储-盖组合及成藏研究,助力番禺4洼恩平组新层系取得大中型油气田勘探发现;创新建立中生代陆缘岩浆弧成岩-成山-成储-成藏模式,指导惠西南取得了古潜山规模商业突破;创新强伸展-弱走滑控盆控烃新机制,推动阳江东—恩平北油田群的重大发现;创新提出"拆离-变质核杂岩"型成盆机制,有望在开平南带形成亿吨级油田群。珠江口盆地逐渐形成古近系、古潜山、新洼陷等勘探新领域及多项技术系列,为南海东、西部油田持续增储上产提供了坚实的技术支撑,也打开了勘探新领域与新类型的勘探前景。资源评价结果显示,珠江口盆地富烃洼陷古近系及古潜山剩余资源量主要分布在惠州26洼、文昌A凹等,阳江—一统暗沙断裂带周缘及惠陆地区周缘新洼陷的原油资源最为丰富。

关键词：富烃洼陷古近系古潜山新洼陷资源潜力珠江口盆地

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于LightGBM模型的甘肃省临夏县滑坡易发性评价

引用

水资源与水工程学报 2024年第1期35卷 197-205,216页

作者：何哲石玉玲李富春贾卓龙晏长根长安大学公路学院陕西西安710064 长安大学地质工程与测绘学院陕西西安710054 中国二十二冶集团有限公司西北分公司陕西西安710119

甘肃省临夏县地质环境复杂,滑坡灾害发育,对当地居民生产生活造成严重威胁,亦对工程建设的开展造成一定阻碍,因此,选取高效准确的机器学习方法对临夏县进行滑坡易发性评价具有重大意义。首先依据遥感影像和野外勘察资料,选取了1718处滑... 详细信息

甘肃省临夏县地质环境复杂,滑坡灾害发育,对当地居民生产生活造成严重威胁,亦对工程建设的开展造成一定阻碍,因此,选取高效准确的机器学习方法对临夏县进行滑坡易发性评价具有重大意义。首先依据遥感影像和野外勘察资料,选取了1718处滑坡样本,遴选了滑坡灾变的16种影响因子并建立滑坡影响因子评价体系;再结合预测精度和运行时间等指标对比了轻量级梯度提升机(LightGBM)模型与主流机器学习模型的性能;最后利用混淆矩阵分级方法进行了基于LightGBM模型的临夏县滑坡易发性评价。结果表明:临夏县重要滑坡影响因子为地表植被和地形地貌因子,其中土地覆盖为最主要影响因子;LightGBM模型预测精度高达0.931,且运行速度仅为11.7 s,既能保证高精度又极大提升了运行效率;在抽稀后的数据集上,LightGBM模型的预测表现、校准程度和分级结果均优于随机森林(RF)模型;混淆矩阵分级法的较高和高易发区内滑坡分布更为集中,在14.94%的区域内分布着86.86%的滑坡灾害点。滑坡易发性评价结果较好地反映了研究区内滑坡分布发育情况,可为当地工程建设及防灾减灾工作提供一定指导。

关键词：滑坡易发性评价轻量级梯度提升机机器学习甘肃省临夏县

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Magnetic graphene oxide-anchored Ni/Cu nanoparticles with a Cu-rich surface for transfer hydrogenation of nitroaromatics

引用

Chinese Journal of Chemical Engineering 2022年第10期50卷 235-246页

作者： Hongbin shi Qing Liu Xiaofeng Dai Teng Zhang yuling shi Tao Wang State Key Lab of Chemical Engineering Department of Chemical EngineeringTsinghua UniversityBeijing 100084China

The bimetallic nanoparticles compositing of Ni-rich core and Cu-rich shell(Ni/Cu NPs)were successfully synthesized by a liquid-phase thermal decomposition *** content of copper and nickel in Ni/Cu NPs was controllable by adjusting the ratio of two metal precursors,copper formate(Cuf)and nickel acetate tetrahydrate(Ni(OAc)_(2)·4H_(2)O).Ni/Cu NPs were further anchored on graphene oxide(GO)to prepare a magnetic composite catalyst,called Ni/*** dispersibility of Ni/Cu NPs in solution was enhanced by GO anchoring to prevent the sintering and aggregation during the reaction process,thereby ensuring the catalytic and cycling performance of the *** catalytic transfer hydrogenation(CTH)reaction of nitroaromatics was investigated when ammonia borane was used as the hydrogen *** dominated the main catalytic role in the reaction,while Ni played a synergistic role of catalysis and providing magnetic properties for *** Ni_(7)/Cu_(3)-GO catalyst exhibited the best catalytic performance with the conversion and yield of 99%and 96%,respectively,when 2-methyl-5-nitrophenol was used as the *** Ni_(7)/Cu_(3)-GO catalyst also exhibited excellent cyclic catalytic performance with the 5-amino-2-methylphenol yield of above 90%after six *** addition,the Ni_(7)/Cu_(3)-GO catalyst could be quickly recycled by magnetic ***,the Ni_(7)/Cu_(3)-GO catalyst showed good catalytic performance for halogen-containing nitroaromatics without dehalogenation.

关键词： Nitroaromatics Transfer hydrogenation Copper-nickel bimetals Core–shell nanoparticles Magnetic catalysts

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

mRNA medicine:Recent progresses in chemical modification,design,and engineering

引用

Nano Research 2024年第10期17卷 9015-9030页

作者： Xiaowen Hou Jinjun shi yuling Xiao Department of Cardiology Zhongnan Hospital of Wuhan UniversitySchool of Pharmaceutical SciencesWuhan UniversityWuhan 430071China Center for Nanomedicine and Department of Anesthesiology Perioperative and Pain MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115USA

Messenger RNA(mRNA)is a type of RNA that carries genetic information from DNA to the ribosome,where it is translated into *** has emerged as a powerful platform for development of new types of medicine,especially after the clinical approval of COVID-19 mRNA *** modification and nanoparticle delivery have contributed to this success significantly by improving mRNA stability,reducing its immunogenicity,protecting it from enzymatic degradation,and enhancing cellular uptake and endosomal ***,substantial progresses have been made in new modification chemistries,sequence design,and structural engineering to generate more stable and efficient next-generation *** innovations could further facilitate the clinical translation of mRNA therapies and *** that numerous review articles have been published on mRNA nanoparticle delivery and biomedical applications over the last few years,we herein focus on overviewing recent advances in mRNA chemical modification,mRNA sequence optimization,and mRNA engineering(e.g.,circular RNA and multitailed mRNA),with the aim of providing new perspectives on the development of more effective and safer mRNA medicines.

关键词： mRNA self-amplifying RNA circular RNA multitailed mRNA chemical modification machine learning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Connectivity of wireless sensor networks for plant growth in greenhouse

引用

International Journal of Agricultural and Biological Engineering 2016年第1期9卷 89-98页

作者： Chen Yang shi yuling Wang Zhongyi Huang Lan College of Information and Electrical Engineering China Agricultural UniversityBeijing 100083China Modern Precision Agriculture System Integration Research Key Laboratory of Ministry of Education Beijing 100083China Key Laboratory of Agricultural information acquisition technology(Beijing) Ministry of AgricultureBeijing 100083China

Wireless sensor networks have been applied in farmland and ***,poor connectivity always results in a lot of nodes isolation in the network in a *** this reason,the network connectivity is worth considering to improve its quality,especially when the collected data cannot be sent to the data center because of the obstacles such as the growth of crop plants and ***,how to reduce the effect of crop growth on network connectivity,and enable the reliable transmission of field information,are the key problems to be *** solve these problems,the method which adds long distance routing nodes to the WSN to reduce the deterioration of WSN connectivity during the growth of plants was *** verify this method,the network connectivity of the deployed WSN was represented by the rank of connection matrix based on the graph ***,the rank with value of 1 indicates a fully connected ***,the smaller value of rank means the better *** addition,the network simulator NS2 simulation results showed that the addition of long-distance backup routing nodes can improve the network ***,in experiments,using ZigBee-based wireless sensor network,a remote monitoring system in greenhouse was established,which can obtain environmental information for crops,***,humidity,light intensity and other environmental parameters as well as the wireless link quality *** results showed adding of long-distance backup routing nodes can guarantee network connectivity in the region where received signal strength indication(RSSI)was poor,*** value was less than−100 dBm,and the energy was *** conclusion,this method was essential to improve the connectivity of WSN,and the optimized method still needs further research.

关键词： wireless sensor network network connectivity long-distance route nodes received signal strength indication(RSSI) greenhouse

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：