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Postoperative abdominal herpes zoster complicated by intestinal obstruction:A case report

World Journal of Clinical Cases 2024年第6期12卷 1138-1143页

作者： Zhen-Yu Dong Rui-xian shi Xiao-Biao Song Ming-Yue Du Ji-Jun Wang Department of General Surgery Baotou Central HospitalBaotou 014040Inner Mongolia Autonomous RegionChina Department of General Surgery Baotou Medical CollegeBaotou 014040Inner Mongolia Autonomous RegionChina Department of Neurology Baotou Central HospitalBaotou 014040Inner Mongolia Autonomous RegionChina Department of Neurology Inner Mongolia Medical UniversityHohhot 010110Inner Mongolia Autonomous RegionChina

BACKGROUND Intestinal obstruction is a common occurrence in clinical ***,the occurrence of herpes zoster complicated by intestinal obstruction after abdominal surgery is exceedingly *** the diagnostic and treatment process,clinicians consider it crucial to identify the primary causes of its occurrence to ensure effective treatment and avoiding *** SUMMARY Herein,we present the case of a 40-year-old female patient with intestinal obstruction who underwent laparoscopic appendectomy and developed herpes zoster after *** the patient's clinical manifestations and relevant laboratory tests,it was suggested that the varicella zoster virus reactivated during the latent period after abdominal surgery,causing herpes ***,the herpes virus invaded the visceral nerve fibers,causing gastrointestinal dysfunction and loss of intestinal peristalsis,which eventually led to intestinal *** patient was successfully treated through conservative treatment and antiviral therapy and subsequently discharged from the *** Pseudo-intestinal obstruction secondary to herpes zoster infection is difficult to distinguish from mechanical intestinal obstruction owing to various *** cases of inexplicable intestinal obstructions,considering the possibility of a viral infection is essential to minimize misdiagnosis and missed diagnoses。

关键词： Herpes zoster Pseudo-intestinal obstruction Ogilvie syndrome Peripheral motor neuropathy Case report

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Microvascular structural changes in esophageal squamous cell carcinoma pathology according to intrapapillary capillary loop types under magnifying endoscopy

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3471-3480页

作者： Wei-Yang shu Yan-Yan shi Jiu-Tian Huang Ling-Mei Meng He-Jun Zhang Rong-Li Cui Yuan Li shi-Gang Ding Department of Gastroenterology Peking University Third HospitalBeijing 100191China Research Center of Clinical Epidemiology Peking University Third HospitalBeijing 10019China Department of Gastroenterology Pathology Laboratory Peking University Third HospitalBeijing 100191China Department of Gastroenterology Peking University International HospitalBeijing 102206China

BACKGROUND The intrapapillary capillary loop(IPCL)characteristics,visualized using magnifying endoscopy,are commonly assessed for preoperative evaluation of the infiltration depth of esophageal squamous cell carcinoma(ESCC).Japan Esophageal Society(JES)classification is the most widely used *** structural changes are evaluated by magnifying endoscopy for the presence or absence of each morphological factor:tortuosity,dilatation,irregular caliber,and different ***,the pathological characteristics of IPCLs have not been thoroughly investigated,especially the microvascular structures corresponding to the deepest parts of the lesions'*** To investigate differences in pathological microvascular structures of ESCC,which correspond to the deepest parts of the lesions'*** Patients with ESCC and precancerous lesions diagnosed at Peking University Third Hospital were enrolled between January 2019 and April *** first underwent magnified endoscopic examination,followed by endoscopic submucosal dissection or surgical *** images were scanned using a threedimensional slice scanner,and the pathological structural differences in different types,according to the JES classification,were analyzed using nonparametric tests and *** The 35 lesions were divided into four groups according to the JES classification:A,B1,B2,and *** analyses revealed significant differences(aP0.05).However,significant differences in the short calibers,long calibers,and area of IPCL were observed between types B1 and B3(aP0.05).CONCLUSION Pathological structures of IPCLs in the deepest infiltrating regions differ among va

关键词： Esophageal squamous cell carcinoma Intrapapillary capillary loop The Japan Esophageal Society classification Magnifying endoscopy Pathological characteristics

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Metal-free two-dimensional phosphorene-based electrocatalyst with covalent P-N heterointerfacial reconstruction for electrolyte-lean lithium-sulfur batteries

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Carbon Energy 2024年第5期6卷 175-185页

作者： Jiangqi Zhou Chengyong shu Jiawu Cui Chengxin Peng Yong Liu Weibo Hua Laura Simonelli Yuping Wu shi Xue Dou Wei Tang School of Chemical Engineering and Technology Xi'an Jiaotong UniversityXi'anChina School of Materials Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina State Key Laboratory of Space Power-Sources Technology Shanghai Institute of Space Power-SourcesShanghaiChina CELLS-ALBA Synchrotron BarcelonaSpain School of Energy and Environment Southeast UniversityNanjingChina

The use of lithium-sulfur batteries under high sulfur loading and low electrolyte concentrations is severely restricted by the detrimental shuttling behavior of polysulfides and the sluggish kinetics in redox ***-dimensional(2D)few layered black phosphorus with fully exposed atoms and high sulfur affinity can be potential lithium-sulfur battery electrocatalysts,which,however,have limitations of restricted catalytic activity and poor electrochemical/chemical *** resolve these issues,we developed a multifunctional metal-free catalyst by covalently bonding few layered black phosphorus nanosheets with nitrogen-doped carbon-coated multiwalled carbon nanotubes(denoted c-FBP-NC).The experimental characterizations and theoretical calculations show that the formed polarized P-N covalent bonds in c-FBP-NC can efficiently regulate electron transfer from NC to FBP and significantly promote the capture and catalysis of lithium polysulfides,thus alleviating the shuttle ***,the robust 1D-2D interwoven structure with large surface area and high porosity allows strong physical confinement and fast mass ***,with c-FBP-NC as the sulfur host,the battery shows a high areal capacity of 7.69 mAh cm^(−2) under high sulfur loading of 8.74 mg cm^(−2) and a low electrolyte/sulfur ratio of 5.7μL mg^(−1).Moreover,the assembled pouch cell with sulfur loading of 4 mg cm^(−2) and an electrolyte/sulfur ratio of 3.5μL mg^(−1) shows good rate capability and outstanding *** work proposes an interfacial and electronic structure engineering strategy for fast and durable sulfur electrochemistry,demonstrating great potential in lithium-sulfur batteries.

关键词： black phosphorus electronic structure high sulfur loading interfacial covalent bonds lean electrolyte

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Anti-osteosarcoma trimodal synergistic therapy using NiFe-LDH and MXene nanocomposite for enhanced biocompatibility and efficacy

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1329-1344页

作者： Yani Xu Lan Yang Min Li Haozhou shu Na Jia Yunzhen Gao Rongying shi Xiaojia Yang Zhirong Zhang Ling Zhang Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry West China School of PharmacySichuan UniversityChengdu 610041China Med-X Center for Materials College of Polymer Science and EngineeringSichuan UniversityChengdu 610065China

Osteosarcoma is usually resistant to immunotherapy and,thus primarily relies on surgical resection and high-dosage ***,less invasive or toxic therapies such as photothermal therapy(PTT)and chemodynamic therapy(CDT)generally failed to show satisfactory *** multimodal therapies with proper safety profiles may provide better solutions for ***,a simple nanocomposite that synergistically combines CDT,PTT,and chemotherapy for osteosarcoma treatment was *** this composite,small 2D Ni Fe-LDH flakes were processed into 3D hollow nanospheres via template methods to encapsulate 5-Fluorouracil(5-FU)with high loading *** nanospheres were then adsorbed onto larger 2D Ti3C2MXene monolayers and finally shielded by bovine serum albumin(BSA)to form 5-FU@Ni Fe-LDH/Ti3C2/BSA nanoplatforms(5NiTiB).Both in vitro and in vivo data demonstrated that the 5-FU induced chemotherapy,Ni Fe-LDH driven chemodynamic effects,and MXene-based photothermal killing collectively exhibited a synergistic“all-in-one”anti-tumor effect.5NiTiB improved tumor suppression rate from<5%by 5-FU alone to~80.1%.This nanotherapeutic platform achieved higher therapeutic efficacy with a lower agent dose,thereby minimizing side ***,the composite is simple to produce,enabling the fine-tuning of dosages to suit different ***,the platform is versatile and efficient,with potential for further development.

关键词： Osteosarcoma NiFe-LDH MXene Chemodynamic therapy Photothermal therapy Chemotherapy 5-Fluorouracil Nanocomposite

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Design and high-power testing of offline conditioning cavity for CiADS RFQ high-power coupler

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Nuclear Science and Techniques 2024年第9期35卷 18-27页

作者： Ruo-Xu Wang Yuan He Long-Bo shi Chen-Xing Li Zong-Heng Xue Tian-Cai Jiang xian-Bo Xu Lie-Peng Sun Zhou-Li Zhang Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Lanzhou University Lanzhou 730000China

To validate the design rationality of the power coupler for the RFQ cavity and minimize cavity contamination,we designed a low-loss offline conditioning cavity and conducted high-power *** offline cavity features two coupling ports and two tuners,operating at a frequency of 162.5 MHz with a tuning range of 3.2 *** the installation angle of the coupling ring and the insertion depth of the tuner helps minimize cavity *** performed electromagnetic structural and multiphysics simulations,revealing a minimal theoretical power loss of 4.3%.However,when the cavity frequency varied by110 kHz,theoretical power losses increased to10%,necessitating constant tuner adjustments during *** simulations indicated that increased cavity temperature did not affect frequency *** completion of the offline high-power conditioning platform,we measured the transmission performance,revealing a power loss of 6.3%,exceeding the theoretical *** utilized efficient automatic range scanning and standing wave resonant *** fully condition the power coupler,a 15°phase difference between two standing wave points in the condition-ing system was ***,the maximum continuous wave power surpassed 20 kW,exceeding the expected target.

关键词： RFQ cavity Power coupler Offline conditioning Resonant cavity

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Design and prototyping of the readout electronics for the transition radiation detector in the high energy cosmic radiation detection facility

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Nuclear Science and Techniques 2024年第4期35卷 189-199页

作者： Jie-Yu Zhu Yang-Zhou Su Hai-Bo Yang Fen-Hua Lu Yan Yang Xi-Wen Liu Ping Wei shu-Cai Wan Hao-Qing Xie xian-Qin Li Cong Dai Hui-Jun Hu Hong-Bang Liu shu-Wen Tang Cheng-Xin Zhao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China

The high energy cosmic-radiation detection(HERD)facility is planned to launch in 2027 and scheduled to be installed on the China Space *** serves as a dark matter particle detector,a cosmic ray instrument,and an observatory for high-energy gamma rays.A transition radiation detector placed on one of its lateral sides serves dual purpose,(ⅰ)calibrating HERD's electromagnetic calorimeter in the TeV energy range,and(ⅱ)serving as an independent detector for high-energy gamma *** this paper,the prototype readout electronics design of the transition radiation detector is demonstrated,which aims to accurately measure the charge of the anodes using the SAMPA application specific integrated circuit *** electronic performance of the prototype system is evaluated in terms of noise,linearity,and *** the presented design,each electronic channel can achieve a dynamic range of 0–100 fC,the RMS noise level not exceeding 0.15 fC,and the integral nonlinearity was<0.2%.To further verify the readout electronic performance,a joint test with the detector was carried out,and the results show that the prototype system can satisfy the requirements of the detector's scientific goals.

关键词： HERD Dark matter particle detection TRD Readout electronics SAMPA Data acquisition Performance test

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Allelopathic potentials of surrounding vegetation on seedling establishment of alpine cushion Arenaria polytrichoides

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Journal of Plant Ecology 2024年第2期17卷 146-160页

作者： Xu-Fang Chen Li-Shen Qian Hong-Hua shi Ya-Zhou Zhang Min-shu Song Hang Sun Jian-Guo Chen Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina University of Chinese Academy of Sciences Beijing 101408China

When facilitating other species and sustaining plant community structures and biodiversity,alpine cushion plants simultaneously experience negative feedback effects from surrounding ***,the impact of surrounding vegetation on cushion dynamics remains poorly understood,particularly in terms of allelopathic *** investigate the allelopathic potentials of surrounding vegetation on seedling establishment of the typical cushion plant Arenaria polytrichoides *** an elevational gradient,we extracted potential allelopathic compounds and tested their impacts on seed germination and seedling growth of *** addition,exclusion experiments using activated carbon were conducted to further elucidate these *** results demonstrate that surrounding vegetation exhibits certain allelopathic potentials on *** seedling establishment,with variations observed based on elevation,source and concentration of allelopathy compounds,as well as growing ***,low-elevation vegetation exerts pronounced suppression on seedling ***,higher-elevation vegetation generally shows no effect on seed germination but stimulates seedling growth through allelopathy ***,aboveground vegetation predominantly inhibits both seed germination and seedling growth in low-elevation communities;however,the effects of belowground vegetation depend on elevation and extract concentration *** identifed allelopathic potentials of surrounding vegetation signifcantly infuence the population dynamics of cushion *** by potentially accelerating population degeneration in lower-elevation communities while ensuring consistent population recruitment and expansion in higher-elevation communities.

关键词： allelopathic potential community dynamic cushion plant seed germination seedling growth

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PIF4 interacts with ABI4 to serve as a transcriptional activator complex to promote seed dormancy by enhancing ABA biosynthesis and signaling

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Journal of Integrative Plant Biology 2024年第5期66卷 909-927页

作者： Xiaofeng Luo Yujia Dai Baoshan xian Jiahui Xu Ranran Zhang Muhammad Saad Rehmani Chuan Zheng Xiaoting Zhao Kaitao Mao Xiaotong Ren Shaowei Wei Lei Wang Juan He Weiming Tan Junbo Du Weiguo Liu shu Yuan Kai shu Shaanxi Key Laboratory of Qinling Ecological Intelligent Monitoring and Protection School of Ecology and EnvironmentNorthwestern Polytechnical UniversityXi'an 710129China Research&Development Institute of Northwestern Polytechnical University in ShenzhenShenzhen 518057China College of Agronomy and Biotechnology China Agricultural UniversityBeijing 100193China Institute of Ecological Agriculture Sichuan Agricultural UniversityChengdu 611130China College of Resources Sichuan Agricultural UniversityChengdu 611130China

Transcriptional regulation plays a key role in the control of seed dormancy,and many transcription factors(TFs)have been ***,the mechanisms underlying the interactions between different TFs within a transcriptional complex regulating seed dormancy remain largely ***,we showed that TF PHYTOCHROME-INTERACTING FACTOR4(PIF4)physically interacted with the abscisic acid(ABA)signaling responsive TF ABSCISIC ACID INSENSITIVE4(ABI4)to act as a transcriptional complex to promote ABA biosynthesis and signaling,finally deepening primary seed *** pif4 and abi4 single mutants exhibited a decreased primary seed dormancy phenotype,with a synergistic effect in the pif4/abi4 double ***4 binds to ABI4 to form a heterodimer,and ABI4 stabilizes PIF4 at the protein level,whereas PIF4 does not affect the protein stabilization of ***,both TFs independently and synergistically promoted the expression of ABI4 and NCED6,a key gene for ABA *** genetic evidence is also consistent with the phenotypic,physiological and biochemical analysis ***,this study revealed a transcriptional regulatory cascade in which the PIF4–ABI4 transcriptional activator complex synergistically enhanced seed dormancy by facilitating ABA biosynthesis and signaling.

关键词： ABA ABI4 PIF4 seed dormancy and germination transcriptional complex

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丙烯酸酯树脂折光指数的计算及与半实验值的比较

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现代化工 2011年第S1期31卷 134-136页

作者：夏宇正石淑先刘辉陈晓农北京化工大学碳纤维及功能高分子教育部重点实验室北京100029

测定了不同种类的丙烯酸酯树脂及其水凝胶的透光率,利用Fresnel关系式,经近似推导得到树脂折光指数的半实验值;利用基团贡献法计算了聚合物的理论折光指数;并将得到的理论值、半实验值和文献值进行了比较。

关键词：丙烯酸酯树脂折光指数透光率

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Highly Hydrolysis-Resistant Polyimide Fibers Prepared by Thermal Crosslinking with Inherent Carboxyl Groups

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Chinese Journal of Polymer Science 2024年第2期42卷 247-255,I0010页

作者： Can-Can Zhang Jun-Long Yang Ya-Jiang Huang Guang-xian Li College of Polymer Science and Engineering State Key Laboratory of Polymer Materials Engineering of ChinaSichuan UniversityChengdu610065China

Easy hydrolysis in alkaline environments limits the use of polyimide fibers in environmental protection. The hydrolysis resistance levels of polyimide fibers can be improved by crosslinking of the macromolecular chains. In this work, crosslinked polyimide fibers(CPI fibers) were produced by intrinsic carboxyl decarboxylation for the first time. The thermal stability of the polyimide fibers containing the intrinsic carboxyl groups(PIC fibers) was studied, and the temperature of the decarboxylation-crosslinking reaction was determined to be 450 ℃. The PIC fibers were hotdrawn to initiate thermal crosslinking of the carboxyl groups and molecular chain orientation at high temperature. The CPI fibers had high tensile strengths(0.72-1.46 GPa) and compressive strengths(401-604 MPa). The oriented macromolecules and chemically crosslinked structure improved the tightness of the molecular chains and endowed the CPI fibers with excellent hydrolytic resistance. The CPI-50 fiber did not dissolve in a 0.5 wt% NaOH solution during heating at 90 ℃ for 10 h, and the tensile strength retention reached 87% when treated in 0.5 wt% NaOH solutions at 90 ℃ for 1 h, providing a guarantee for its application in alkaline corrosive environments.

关键词： Polyimide Carboxyl group Crosslinking Hydrolysis-resistance

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