检索结果-南通市图书馆

World Journal of Clinical Cases 2019年第21期7卷 3622-3631页

作者： Bo-Han Li shao-yan hu Department of Hematology and Oncology Children’s Hospital of Soochow University

BACKGROUND Timely reconstitution of a donor-derived immune system is important for recovery and long-term survival of patients after allogeneic hematopoietic stem cell transplantation(HSCT).We describe a case of Wiskott–Aldrich syndrome(WAS)treated by umbilical cord blood transplantation(UCBT)with atypical immune *** SUMMARY A 1-year-old Chinese male infant was diagnosed with *** gene sequencing identified the mutation c.777+1G>A(IVS8).On August 8,2017,he was admitted to our hospital for *** selected an unrelated human leukocyte antigen 6/10-matched donor for *** HSCT,the immune reconstitution process was atypical,the lymphocytes reached 0.5×109/L on day 23,and the neutrophils reached 0.5×109/L on day *** patient’s recovery throughout the year was *** An increase in lymphocytes(especially T cells)earlier than granulocytes may be a marker of a good prognosis in UCBT.

关键词： Umbilical cord blood transplantation Wiskott-Aldrich syndrome Immune reconstruction Case report

Multi-index analysis of the melting process of laterite metallized pellet

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2018年第12期25卷 1423-1430页

作者： Yun Wang Rong Zhu Kai-lu Tu Guang-sheng Wei shao-yan hu Hong Li School of Metallurgical and Ecological Engineering University of Science and Technology Beijing

Herein, a multi-index analysis of the nickel content of an alloy, output rate of the alloy, nickel recovery rate, and iron recovery rate during the melting of laterite metallized pellets was performed. The thermodynamic reduction behavior of oxides such as NiO, FeO, Fe_3 O_4, and Cr_2 O_3 was studied using the FactSage software, which revealed that SiO_2 is not conducive to the reduction of iron oxides, whereas the addition of basic oxides such as CaO and MgO is beneficial for the reduction of iron oxides. On the basis of a comprehensive analysis to achieve greater nickel recovery and lower iron recovery rates, the optimum experimental parameters in the orthogonal experiment were A3 B1 C3(t = 30 min, C/O = 0.4, R = 1.2); the indicators wNi, φalloy, ηNi, and ηFe had values of 15.0 wt%, 12.1%, 44.9%, and 96.4%, respectively. In single-factor experiments, increasing basicity(R) substantially improved the separation effect in the low-basicity range 0.5 ≤ R ≤ 0.8 but not in the high-basicity range 0.8 ≤ R ≤ 1.2. Similar results were obtained for the effect of the C/O ratio. Moreover, the recovery rate of nickel increased with increasing recovery rate of iron.

关键词： melting and separation laterite metallized pellet multi-index analysis basicity carbon-to-oxygen ratio

Interface characteristics between TiN and matrix and their effect on solidification structure

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2021年第9期28卷 1149-1158页

作者： Tian-peng Qu De-yong Wang hui-hua Wang Dong Hou Jun Tian shao-yan hu Li-juan Su Shagang School of Iron and Steel Soochow UniversitySuzhou215021JiangsuChina

Heterogeneous nucleation is an effective way to promote the dispersion and precipitation of second-phase particles in steel and refine the grain size of the solidification *** only refining as-cast structure grain size,but TiN in ferritic stainless steel can also pin grain boundaries and restrain the overgrowth of grains during *** interface characteristics between TiN and heterogeneous phases(high-melting inclusions and ferrite phase)were studied based on the wetting angles between molten steel with different compositions and TiN substrate,and on the matching degree between TiN and ferrite *** was found that,for the molten steel with the same composition,the wetting angle with the TiN substrate was significantly smaller than the contact angles with the other three substrates,while the wetting angle between ferrite phase and TiN was the *** lattice matching was compared among MgAl_(2)O_(4),TiN andδmatrix by means of a high-resolution transmission electron microscope,which revealed that a coherent or semi-coherent interface was formed between the crystal plane(400)of MgAl_(2)O_(4)and the crystal plane(200)of TiN,as well as between the crystal plane(200)of TiN and the crystal plane(110)ofδmatrix,with a lattice misfit of 5.1%and 3.4%,***,these two characteristics between TiN and ferrite phase were both explained from the perspective of interfacial *** microstructure refinement mechanism from high temperature to room temperature can be better reflected by the proposed wetting–lattice misfit theory.

关键词： TiN Heterogeneous nucleation Interfacial wetting Lattice matching Grain refinement

Numerical simulation and experimental measurement of transport phenomena for coherent jet with CH4 ＋ N2 mixed fuel gas

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2018年第1期25卷 28-36页

作者： shao-yan hu Rong Zhu Run-zao Liu Kai Dong Fu-hai Liu Guo-hong Ma Rong-fang Su School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083 China Beijing Key Laboratory of Research Center of SpecialMelting and Preparation of High-end Metal Materials University of Science and Technology BeijingBeijing 100083 China Rongcheng Jingye Technology Limited Company Beijing Beijing 100083 China

Coherent jet technology has been widely used in EAF steelmaking process because of the longer potential core length and stronger impacting power of the supersonic oxygen jet. However, more oxygen and fuel gas are consumed to achieve excel- lent characteristics of coherent jets, which causes the increase in steelmaking cost. Computational fluid dynamics simulation and experimental measurement of the coherent jets with CH4 ＋ N2 mixed fuel gas were carried out aiming at reducing the consumption of fuel gas. The numerical simulation results showed good agreement with the experimental data. As a result, high proportion of N2 negatively affects the combustion of CH4, which is not good for the protection of oxygen jets. While the gas composition is 75% CH4 ＋ 25% N2, the N2 addition to the CH4 leads to an expanding of CH4 combustion zone, and the energy generated by the combustion reaction could be delivered to the molten bath more efficiently, which is one control scheme with high performance-price ratio.

关键词： Electric arc furnace Coherent jet Numerical simulation Jet measurement Mixed fuel gas

Cytogenetic Characteristics of Childhood Acute Lymphoblastic Leukemia:A Study of 1541 Chinese Patients Newly Diagnosed between 2001 and 2014

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Medical Science 2022年第1期42卷 201-209页

作者： Meng-meng YIN Rui-chi WU Jing GAO shao-yan hu Xiao-ming LIU Xiao-fan Zhu Shu-hong SHEN Jing-yan TANG Jing CHEN Qun hu Department of Pediatric Hematology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Hematology/Oncology Shanghai Children’s Medical CenterShanghai Jiaotong University School of MedicineShanghai 200000China Children’s Hospital of Soochow University Suzhou 215000China State Key Laboratory of Experimental Hematology National Clinical Research Center for Blood DiseasesInstitute of Hematology&Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300000China

Objective:Cytogenetic abnormalities have been proven to be the most valuable parameter for risk stratification of childhood acute lymphoblastic leukemia(ALL).However,studies on the prevalence of cytogenetic abnormalities and their correlation to clinical features in Chinese pediatric patients are limited,especially large-scale ***:We collected the cytogenetics and clinical data of 1541 children newly diagnosed with ALL between 2001 and 2014 in four Chinese hospitals,and retrospectively analyzed their clinical features,prognosis and risk factors associated with pediatric ALL.

关键词： cytogenetics characteristics childhood Chinese acute lymphoblastic leukemia.

Saponins from Paris forrestii(Takht.) H. Li displays potent activity against acute myeloid leukemia by suppressing RNF6/AKT/mTOR signaling pathway

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国药理学与毒理学杂志 2018年第4期32卷 260-261页

作者： Qin LU Yuan-ming HE Yue-hu WANG Li GAO Yun-jing ZHENG Zu-bin ZHANG Bi-yin CAO Qi WANG Xin-liang MAO shao-yan hu Department of Hematology & Oncology Children's Hospital of Soochow University Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences Soochow University Kunming Institute of Botany Chinese Academy of Sciences Institute of Clinical Pharmacology Guangzhou University of Chinese Medicine

Acute myeloid leukemia(AML) is a heterogeneous disease characterized by the *** of immature myeloid progenitor cells in the bone marrow,compromising of normal *** and ultimately resulting in bone marrow *** is the mainstay treatment for all AML patients,however,drug resistance and clinical relapse limits its *** 5-year survival rate of AML patients is only 26.6%.Survival rates are even lower among patients ages 65 to 74 years(5.3%) and 75 years or older(1.6%).Therefore,exploring novel therapeutic agents is urgent for improving the outcome of patients with *** are amphipathic glycosides found in traditional Chinese *** the present study,we isolated a panel of saponins from Paris forrestii(Takht.) ***,a unique plant found in Tibet and Yunnan provinces,*** examining their activities in suppressing acute myeloid leukemia cell proliferation,total saponins from Paris forrestii(TSPf) displayed more potent activity than individual *** induced more than 40% AML cell apoptosis within 24 h and decreased the viability of all leukemia cell ***-induced apoptosis was confirmed by both Annexin V staining and caspase-3 *** downregulated pro-survival proteins Mcl-1,Bcl-xL and Bcl-2,but *** the expression of tumor suppressor proteins p53,p27,Bax and Beclin *** AKT/mTOR signaling pathway is frequently over activated in various AML cells,and TSPf was found to suppress the *** of both AKT and mTOR,but had no effects on their total protein *** was further *** by the inactivation of 4 EBP-1 and p70 S6 K,two typical downstream signal molecules in the AKT/mTOR *** specifically,TSPf-inactivated AKT/mTOR signaling was found to be associated with downregulated RNF6,a recently identified oncogene in ***6 activated AKT/mTOR,and consistently,knockdown of RNF6 led to inactivation of the AKT/mTOR ***,TSPf suppressed the growth of AML xenog

关键词：急性髓系白血病骨髓衰竭治疗方法临床分析

在线全文

学校读者我要写书评

暂无评论

拥塞控制卫星PRMA-AC协议及性能分析

电子与信息学报 2006年第3期28卷 446-450页

作者：卓永宁严少虎吴诗其电子科技大学抗干扰通信国家重点实验室成都610054

卫星通信中PRMA协议在负荷较重时由于终端竞争加剧会引起信道拥塞,而较长的传播时延更进一步加剧了拥塞引起的丢包。该文提出一种利用话音终端在通话的不同阶段对信道资源的不同需求对终端进行区分的方案PRMA-AC,据此引入一种接入控制机... 详细信息

卫星通信中PRMA协议在负荷较重时由于终端竞争加剧会引起信道拥塞,而较长的传播时延更进一步加剧了拥塞引起的丢包。该文提出一种利用话音终端在通话的不同阶段对信道资源的不同需求对终端进行区分的方案PRMA-AC,据此引入一种接入控制机制,以减少信道竞争,提高系统服务质量。文中给出了系统模型,对协议性能进行了理论分析,获得了新协议下的接入阻塞率、丢包率等性能指标,最后通过仿真与几种卫星通信中常用的PRMA协议进行了对比,证明了协议的性能。

关键词：卫星通信分组预约多组接入(PRMA) 分组预约拥塞控制

在线全文

学校读者我要写书评

暂无评论

多小区无线局域网的系统吞吐率估计算法

电子与信息学报 2005年第9期27卷 1493-1497页

作者：凌翔阳坤严少虎吴诗其电子科技大学抗干扰通信国防重点实验室成都610054 香港大学电机电子工程系

在多小区无线局域网(Wireless Local Area Networks,WLAN)中,由于存在小区间接入访问点同频干扰,以及小区间同频用户干扰,其系统性能与单小区网络具有很大不同。本文提出了支持多种用户传输速率共存、支持用户非均匀分布的多小区WLAN系... 详细信息

在多小区无线局域网(Wireless Local Area Networks,WLAN)中,由于存在小区间接入访问点同频干扰,以及小区间同频用户干扰,其系统性能与单小区网络具有很大不同。本文提出了支持多种用户传输速率共存、支持用户非均匀分布的多小区WLAN系统吞吐率估计算法。通过对多小区WLAN巾接入访问点的布置、信道的配置进行仿真,结果表明即使在存在小区间同频干扰的情况下,估计算法也能得到满意的吞吐率估计结果。

关键词：无线局域网 IEEE 802.11 系统吞吐率估计算法

IEEE 802.11 DCF中带优先级的退避算法

在线全文

学校读者我要写书评

暂无评论

电子与信息学报 2005年第8期27卷 1315-1319页

作者：严少虎卓永宁吴诗其郭伟电子科技大学通信抗干扰技术国家级重点实验室成都610054

该文针对IEEE802.11DCF提出一个带优先级的退避算法。算法的基本思想是网络中的节点在侦听信道的同时,搜集其他节点发送数据的统计信息,并在本地维护一个关于节点已发送数据量的统计表。当节点有数据需要发送时,将根据表巾的统计数据以... 详细信息

该文针对IEEE802.11DCF提出一个带优先级的退避算法。算法的基本思想是网络中的节点在侦听信道的同时,搜集其他节点发送数据的统计信息,并在本地维护一个关于节点已发送数据量的统计表。当节点有数据需要发送时,将根据表巾的统计数据以及本节点的优先级来计算竞争窗口。计算机仿真证明,该算法能很好地完成网络的信道容量在不同优先级的节点之间按一定的比例分配,同时还可提高整个网络的吞吐率。

关键词：退避算法优先级 IEEE802.11 分布式协调功能

IEEE802.11DCF中基于能耗最小的RTS门限自适应调整算法

在线全文

学校读者我要写书评

暂无评论

电子与信息学报 2005年第12期27卷 1983-1987页

作者：严少虎卓永宁吴诗其郭伟电子科技大学通信抗干扰技术国家级重点实验室成都610054

该文通过数学模型分析IEEE 802.11网络中，终端采用分布式协调功能(DCF)方式发送一个数据包消耗的平均能量。研究发现，存在一个使终端发送的平均能耗最小的最佳RTS门限，它与终端的平均重传次数直接相关。在此基础上，该文提出了一个RT... 详细信息

该文通过数学模型分析IEEE 802.11网络中，终端采用分布式协调功能(DCF)方式发送一个数据包消耗的平均能量。研究发现，存在一个使终端发送的平均能耗最小的最佳RTS门限，它与终端的平均重传次数直接相关。在此基础上，该文提出了一个RTS门限调整算法。计算机仿真结果证明该算法能使终端根据网络环境自适应地调整RTS门限到最佳值，从而减少发送过程中的能量消耗。

关键词： IEEE 802.11 分布式协调功能 RTS门限自适应调整算法能量消耗