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IDS-INT:Intrusion detection system using transformer-based transfer learning for imbalanced network traffic

Digital Communications and Networks 2024年第1期10卷 190-204页

作者： Farhan ullah shamsher ullah Gautam Srivastava Jerry Chun-Wei Lin School of Software Northwestern Polytechnical UniversityXian710072ShaanxiChina Knowledge Unit of Systems and Technology University of Management and TechnologySialkot 51040Pakistan Department of Math and Computer Science Brandon UniversityBrandonMB R7A 6A9Canada Department of Computer Science and Math Lebanese American UniversityBeirut1102Lebanon Western Norway University of Applied Sciences BergenNorway Research Centre for Interneural Computing China Medical UniversityTaichungTaiwanChina

A network intrusion detection system is critical for cyber security against llegitimate *** terms of feature perspectives,network traffic may include a variety of elements such as attack reference,attack type,a subcategory of attack,host information,malicious scripts,*** terms of network perspectives,network traffic may contain an imbalanced number of harmful attacks when compared to normal *** is challenging to identify a specific attack due to complex features and data imbalance *** address these issues,this paper proposes an Intrusion Detection System using transformer-based transfer learning for Imbalanced Network Traffic(IDS-INT).IDS-INT uses transformer-based transfer learning to learn feature interactions in both network feature representation and imbalanced ***,detailed information about each type of attack is gathered from network interaction descriptions,which include network nodes,attack type,reference,host information,***,the transformer-based transfer learning approach is developed to learn detailed feature representation using their semantic ***,the Synthetic Minority Oversampling Technique(SMOTE)is implemented to balance abnormal traffic and detect minority ***,the Convolution Neural Network(CNN)model is designed to extract deep features from the balanced network ***,the hybrid approach of the CNN-Long Short-Term Memory(CNN-LSTM)model is developed to detect different types of attacks from the deep *** experiments are conducted to test the proposed approach using three standard datasets,i.e.,UNsWNB15,CIC-IDS2017,and *** explainable AI approach is implemented to interpret the proposed method and develop a trustable model.

关键词： Network intrusion detection Transfer learning Features extraction Imbalance data Explainable AI Cybersecurity

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τ-Access Policy:Attribute-Based Encryption Scheme for Social Network Based Data Trading

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China Communications 2021年第8期18卷 183-198页

作者： shamsher ullah Lan Zhang Muhammad Wasif Sardar Muhammad Tanveer Hussain School of Software Northwestern Polytechnical UniversityXi’an 710072ShaanxiChina School of Computer Science and Technology University of Science and Technology of China Hefei 230026AnhuiChina Department of Electronics and Electrical Systems University of LahorePunjab54000Pakistan School of Science Department of MathematicsUniversity of Management and TechnologyLahore54770Pakistan.

The rapid development of social technology has replaced physical interaction in the trading *** implication of this technology is to provide access to the right information at the right *** drawback of these technologies is that the eavesdropper can remove the user from the network and can create proxy *** this paper,we discuss how a social network overcome and prevent these data trading *** maintain the security of data trading,we applied ABE technique based on DBDH to secure data trading *** proposedτ-access policy scheme provides the best solution for the betterment of data trading network in terms of ***τ-access policy scheme,the users can encrypt and decrypt Private Transactions Information(PTI)using our proposedτ-access *** security properties ofτ-access policy are data confidentiality,data integrity,authenticity,non-repudiation,and *** efficiency of our scheme is 77.73%,which is more suitable for data trading markets and trading strategies.

关键词： ABE privacy integrity data trading PTI τ-access policy

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Neuroprotective potential of Quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

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Neural Regeneration Research 2017年第7期12卷 1137-1144页

作者： shamsher Singh Sumit Jamwal Puneet Kumar Department of Pharmacology I.S.F College of Pharmacy Ferozepur Road Moga Punjab India I.K. Gujral Punjab Technical University Jalandhar Punjab India

1-Methy-4-phenyl-1,2,3,6-tetrahydropyridine（MPTP）is a neurotoxin that selectively damages dopaminergic neurons in the substantia nigra pars compacta and induces Parkinson＇s like symptoms in ***（QC）is a natural polyphenolic bioflavonoid with potent antioxidant and anti-inflammatory properties but lacks of clinical attraction due to low oral *** is a well established bioavailability enhancer used pre-clinically to improve the bioavailability of antioxidants（e.g.,Quercetin）.Therefore,the present study was designed to evaluate the neuroprotective potential of QC together with piperine against MPTP-induced neurotoxicity in ***（100μg/μL/rat,bilaterally）was injected intranigrally on days 1,4 and 7 using a digital stereotaxic ***（25 and 50 mg/kg,intragastrically）and QC（25 mg/kg,intragastrically）in combination with piperine（2.5 mg/kg,intragastrically）were administered daily for 14 days starting from day 8 after the 3^（rd） injection of *** day 22,animals were sacrificed and the striatum was isolated for oxidative stress parameter（thiobarbituric acid reactive substances,nitrite and glutathione）,neuroinflammatory cytokine（interleukin-1β,interleukin-6,and tumor necrosis factor-α）and neurotransmitter（dopamine,norepinephrine,serotonin,gamma-aminobutyric acid,glutamate,3,4-dihydroxyphenylacetic acid,homovanillic acid,and 5-hydroxyindoleacetic acid）*** infusion of MPTP into substantia nigra pars compacta led to significant motor deficits as evidenced by impairments in locomotor activity and rotarod performance in open field test and grip strength and narrow beam walk *** QC（25 and 50 mg/kg）and QC（25 mg/kg）in combination with piperine（2.5 mg/kg）,in particular the combination therapy,significantly improved MPTP-induced behavioral abnormalities in rats,reversed the abnormal alterations of neurotransmitters in the striatum,and alleviated oxidative stress and inflammatory response in the *** f

关键词： nerve regeneration 1-methy-4-phenyl-1,2,3,6-tetrahydropyridine Quercetin Piperine Parkinson'sdisease excitotoxicity oxido-nitrosative stress neurotransmitters neural regeneration

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Sericin alleviates pentylenetetrazole kindling epilepsy and associated comorbidities via modulation of GABA-T enzyme and mitochondrial activity

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Asian Pacific Journal of Tropical Biomedicine 2023年第10期13卷 431-442页

作者： Sania Grover Raj Kumar Narang shamsher Singh I.K.Gujral Punjab Technical University JalandharPunjabIndia Department of Pharmaceutics ISF College of Pharmacy(An Autonomous College)Moga-142001PunjabIndia Neuroscience Division Department of PharmacologyISF College of Pharmacy(An Autonomous College)Moga-142001PunjabIndia

Objective:To assess the effect of sericin against pentylenetetrazole(PTZ)kindling epilepsy and its associated ***:Epilepsy was induced with PTZ at the dose of 30 mg/kg *** alternative days for 25 days in *** was administered orally at the doses of 250,500,and 1000 mg/kg for 35 *** behavioral activities were performed using an elevated plus maze,forced swim test,and Morris water maze test.A PTZ challenge test was conducted on day *** day 35,rats were sacrificed to perform oxidative stress,mitochondrial dysfunction,neuroinflammation,neurotransmitters,GABA-T activity,and histopathological ***:Sericin at 500 and 1000 mg/kg significantly reduced behavioral changes and neuroinflammatory cytokines,as well as improved oxidative stress,mitochondrial enzyme complex activity,neurotransmitter level,and GABA-T enzymatic activity(P<0.05).Moreover,sericin improved the neuronal survival altered by PTZ kindling in rat ***:Sericin mitigates epilepsy-associated secondary complications possibly by the modulation of mitochondrial enzyme complexes and GABA-T enzymatic activity.

关键词： Pentylenetetrazole Sericin GABA-T Epilepsy Anxiety Cognitive impairment

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Cryptotanshinone ameliorates cladribine-induced cognitive impairment in rats

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Asian Pacific Journal of Tropical Biomedicine 2023年第7期13卷 296-305页

作者： Khadga Raj Aran G.D.Gupta shamsher Singh Neuroscience Division Department of PharmacologyISF College of Pharmacy(An Autonomous College)MogaPunjabIndia-142001 I.K.Gujral Punjab Technical University JalandharIndia Department of Pharmaceutics ISF College of PharmacyMogaPunjabIndia-142001

Objective:To evaluate the neuroprotective effect of cryptotanshinone against cladribine-induced cognitive impairment in ***:Rats were administered with cladribine(1 mg/kg,p.o.)and cryptotanshinone(10 and 20 mg/kg,i.p.)for four *** tests such as Morris water maze and elevated plus maze were conducted to check memory impairment caused by *** day 29,all rats were sacrificed,and the brains were separated for estimation of neuroinflammatory factors,biochemical parameters,neurotransmitters,Aβ(1-42),blood-brain barrier permeability,nuclear factor erythroid 2-related factor 2(Nrf2),and brain-derived neurotrophic factor(BDNF).Results:Treatment with cryptotanshinone dose-dependently enhanced spatial memory,improved the levels of neurotransmitter and antioxidant enzymes,and suppressed proinflammatory cytokine *** also decreased Aβ(1-42)accumulation and increased the levels of Nrf2 and BDNF in the ***,the histopathological results showed that cryptotanshinone reduced cladribine-induced neuronal death in the ***:Cryptotanshinone exhibits a promising neuroprotective effect against cladribine-induced cognitive impairment in preclinical studies,and may be a potential phytochemical for the treatment and management of cognitive impairment.

关键词： Alzheimer's disease Cladribine Cryptotanshinone Neurotransmitters Neuroprotective Proinflammatory cytokines Cognitive deficit

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Maximum sustainable yield of Greater lizardfish Saurida tumbil fishery in Pakistan using the CEDA and ASPIC packages

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Acta Oceanologica Sinica 2015年第2期34卷 68-73页

作者： KALHORO Muhsan Ali LIU Qun MEMON Khadim Hussain WARYANI Baradi SOOMRO shamsher Hyder College of Fisheries Ocean University of China Marine Fisheries Department Fish Harbor West Wharf Karachi Department of Freshwater Biology and Fisheries University of Sindh

The catch and effort data analysis（CEDA） and ASPIC（a stock assessment production model incorporating covariates） computer software packages were used to estimate the maximum sustainable yield（MSY） from the catch and effort data of Greater lizardfish Saurida tumbil fishery of Pakistan from 1986 to 2009. In CEDA three surplus production models of Fox, Schaefer and Pella-Tomlinson were used. Here initial proportion（IP） of 0.5 was used because the starting catch was roughly 50% of the maximum catch. With IP = 0.5, the estimated MSY from Fox model were 20.59 mt and 38.16 mt for normal and log-normal error assumptions, while the MSY from Schaefer and Pella-Tomlinson were 60.40, 60.40 and 60.40 mt, for normal, log-normal and gamma error assumptions respectively. The MSY values from Schaefer and Pella-Tomlinson models of three error assumptions were the same. The R2 values from those three models were above 0.6. When IP = 0.5, the MSY values estimated from ASPIC from Fox were 132 mt, and from logistic model were 69.4 mt, with R2 value above 0.8. Therefore we suggest the MSY of S. tumbil fishery from Pakistan to be 60–70 mt, which is higher than the latest catch, thus we would recommend that the fishing efforts for this fishery may be kept at the current level.

关键词： Pakistan Sauridatumbil ASPIC CEDA MSY

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Development of New Submergence Tolerant Rice Variety for Bangladesh Using Marker-Assisted Backcrossing

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Rice science 2015年第1期22卷 16-26页

作者： Khandakar Md IFTEKHARUDDAULA Helal Uddin AHMED Sharmistha GHOSAL Zakiah Rahman MONI Al AMIN Md shamsher ALI Plant Breeding Division Bangladesh Rice Research Institute

Submergence tolerant high yielding rice variety was developed using BR11 as a recipient parent applying foreground, phenotypic and background selection approaches. Recombinant selection was found essential to minimize linkage drag by BC2F2 generation. Without recombinant selection, the introgression size in the backcross recombinant lines （BRLs） was approximately 15 Mb on the carrier chromosome. The BRLs were found submergence tolerance compared to the check varieties under complete submergence for two weeks at Bangladesh Rice Research Institute, and produced higher yield compared to the isogenic Subl-line under controlled submerged condition. The BRL IR85260-66-654-Gaz2 was released as BRRI dhan52 in 2010, which was the first high yielding submergence tolerant variety in Bangladesh. BRRI dhan52 produced grain yield ranging from 4.2 to 5.2 t/hm2 under different flash flood prone areas of Bangladesh in three consecutive seasons. The study demonstrated the efficiency of recombinant selection and better adaptability of the newly released submergence tolerant high yielding variety in flash flood prone different areas of the country with respect to submergence tolerance and yield potential.

关键词： backcross recombinant line marker-assisted backcrossing recombinant selection rice submergence tolerance

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A Study on the Impact of PEST Analysis on the Pharmaceutical Sector： The Bangladesh Context

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Journal of Modern Accounting and Auditing 2011年第12期7卷 1446-1456页

作者： Mohammad Nayeem Abdullah Robaka shamsher Independent University Bangladesh

PEST （Political, Economic, Social, and Technological） analysis of any industry sector investigates the important factors that are affecting the industry and influencing the companies operating in that sector. The purpose of this study is to analyze the pharmaceutical sector of Bangladesh using the framework of PEST. This report brings to light the current state of the sector its progress and its problems. Through this study the researchers try to discuss the affect of various macro-economic factors of political, economic, social, and technological aspect on the industry and its related problems and prospects for the future.

关键词： PEST analysis pharmaceutical sector industry and macro economic factors

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Effects of Boundary Conditions on Postbuckling Strengths of Composite Laminate with Various Shaped Cutouts under In-Plane Shear

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Open Journal of Composite Materials 2013年第2期3卷 38-50页

作者： Dinesh Kumar shamsher Bahadur Singh Department of Civil Engineering Birla Institute of Technology and Science (BITS) Pilani India.

Cutouts are often provided in composite structural components for practical reasons. For instance, aircraft components such as wingspar, fuselage and ribs are provided with cutouts for access, inspection, fuel lines and electric lines or to reduce the overall weight. This paper addresses the effect of boundary condition on buckling and postbuckling responses, failure loads, and failure characteristics of composite laminate with various shaped cutouts (i.e., circular, square, diamond, elliptical-vertical and elliptical-horizontal) and having different lay-ups under in-plane shear (positive and negative) load, using finite-element method. The FEM formulation is based on the first order shear deformation theory in conjunction with geometric nonlinearity using von Karman’s assumptions. The 3-D Tsai-Hill criterion is used to predict the failure of a lamina while the onset of delamination is predicted by the interlaminar failure criterion. It is observed that the effect of boundary condition on buckling, first-ply failure and ultimate failure loads of a quasi-isotropic laminate with cutout is more for positive shear load than that for the negative shear load for almost all cutout shapes. It is also noted that under in-plane shear loads postbuckling stiffness of (0/90)4s laminate with circular cutout is maximum, while it is minimum for (45/—45)4s laminate with circular cutout, irrespective of boundary conditions.

关键词： Boundary Conditions Buckling Postbuckling Cutouts Composite Laminate FEM

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Cholesterol Oxidase and Its Applications

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Advances in Microbiology 2012年第2期2卷 49-65页

作者： Lata Kumari shamsher S. Kanwar Department of Biotechnology Himachal Pradesh University Shimla India

Cholesterol oxidase (COX), a bi-functional FAD-containing microbial enzyme belongs to the family oxidoreductases. COX catalyses the oxidation of cholesterol into 4-cholesten-3-one. In recent time, cholesterol oxidase has received great attention due to its wider use in clinical (determination of serum cholesterol) laboratories practice and in the biocatalysis for the production of a number of steroids. COX has been shown to possess potent insecticidal activity, besides its use to track cell cholesterol. Moreover, COX is also implicated in the manifestation of some of the diseases of bacterial (tuberculosis), viral (HIV) and non-viral prion origin (Alzheimer's). These applications and disease mechanisms have promoted the need of screening, isolation and characterization of newer microbes from diverse habitats as a source of COX to learn more about its structural and functional aspects. In this review, we discuss microbial sources of COX, its structure and important biochemical properties besides its broad range of biological functions and applications.

关键词： Microbial Cholesterol Oxidase Cholesterol Flavoprotein Diagnostic Enzyme Steroids

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