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Acarine ectoparasites of Panti Forest Reserve in Johore,Malaysia

Asian Pacific Journal of Tropical Biomedicine 2011年第1期1卷 1-5页

作者： Mariana A Mohd Kulaimi B Halimaton I Suhaili ZA shahrul-anuar ms Nor Zalipah M Ho TM Acarology Unit Infectious Diseases Research CentreInstitute for Medical Research School of Biological Sciences Universiti Sains Malaysia Department of Biological Sciences Faculty of Science and TechnologyUniversiti Malaysia Terengganu

Objective:To identify the presence of acarine ectoparasites and determine whether there is any potential public health risk in Panti Forest Reserve,Johore,***:Trapping of animals and avifauna was conducted simultaneously along 5 expedition trails using 150 wire traps,10 harp traps and 30 mist nets for 6 consecutive nights.A total of 140 animals consisting of 7 species of birds,19 species of bats,6 species of rodents and 1 species of tree-shrew as well as 8 myriapods were ***:Infestation rates of ticks,mesostigmatid mites and chiggers on animals examined were 24.3%,28.6%and 27.9%,*** on bats was low(1.5%) and none occurred on *** of ticks extracted were at immature stages(78.9%). Genera of ticks on animals were Amblyomma,Dermacentor,Haemaphysalis and *** granulatus was the only species of licks identified from the *** of ticks under vegetation revealed 54%adults leading to identification of 3 species of ticks.A total of 7 species of mesostigmatid mites were found.6 species were on rodent,Maxomys mrifer and another one species,Laelaps nuttalli was found only on Leopoldamys *** sanguisugus was the only mesostigmatid found infesting *** genera of chiggers were *** this,5 genera were on rodents,4 genera on tree-shrews and 1 genus on a ***:A total of 16 genera,2 sub-genus and 14 species of acarine ectoparasites were found in this area. Findings of the survey demonstrate the presence of three spesies of acarine ectoparasites which have potential health risk *** granulalus,Laelaps nuttalli and Leptotrombidium deliense.

关键词： Acarine ectoparasites Panti Forest Reserve Malaysia Public health risk Infestation rate Tick Mesostigmatid mite Chigger Ixodes granulatus Laelaps nuttalli Leptotrombidium deliense Avifauna Rodent

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Occurrence of K1 and K2 serotypes and genotypic characteristics of extended spectrumβ-lactamases-producing Klebsiella pneumoniae isolated from selected hospitals in Malaysia

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Asian Pacific Journal of Tropical Medicine 2024年第1期17卷 30-38页

作者： Nurul Syazrah anuar Hazmin Hazman Sharven Raj Jeyakumar Mohd Nasir Mohd Desa Hasni Idayu Saidi Siti Norbaya Masri Nur Afiza Aziz Nurshahira Sulaiman Department of Biomedical Science Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400UPM SerdangSelangorMalaysia Department of Medical Microbiology Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400UPM SerdangSelangorMalaysia Microbiology Unit Department of PathologyHospital Sultanah AminahJalan Persiaran Sultan Abu Bakar80100 Johor BahruJohorMalaysia

Objective:To determine the distribution,phenotypic and genetic background of extended spectrumβ-lactamases(ESBL)-producing Klebsiella(K.)pneumoniae clinical isolates associated with K1 and K2 serotypes in two selected hospitals in ***:A total of 192 *** isolates were collected and subjected to antibiotic susceptibility,hypermucoviscosity test and multiplex PCR to detect the presence of K1-and K2-serotype associated *** sequence typing(MLST)was performed on ESBL-producing *** isolates presented with K1 and K2 serotypes,followed by phylogenetic ***:A total of 87 out of 192(45.3%)of the *** isolates collected were ESBL ***,only 8.3%(16/192)and 10.9%(21/192)of the total isolates were detected to carry K1-and K2-serotype associated genes,*** analysis showed that K1 and K2 capsular serotypes were not significantly associated with ESBL phenotype(P=0.196).However,they were significantly associated with hypervirulent,as demonstrated by the positive string test(P<0.001).MLST analysis revealed that ST23 as the predominant sequence type(ST)in the K1 serotype,while the ST in the K2 serotype is more ***:Although the occurrence of ESBL-producing isolates among the hypervirulent strains was low,their coexistence warrants the need for continuous *** showed that these isolates were genetically heterogeneous.

关键词： Extended spectrumβ-lactamases Klebsiella pneumoniae Capsular serotypes Genotypic

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多盘连续可变工作间隙磁流变制动器仿真与验证

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重庆大学学报 2024年第8期47卷 26-38页

作者：李东恒王娜 Saiful anuar Abu Bakar 宋万里马来西亚理工大学汽车发展中心马来西亚新山81310 马来西亚理工大学机械工程学院马来西亚新山81310 柳州职业技术大学机电工程学院广西柳州545006 东北大学机械工程与自动化学院沈阳110819

为提高磁流变制动器制动能效,提出一种多盘连续可变磁流变液工作间隙结构的磁流变制动器。在ANSYS workbench环境下完成不同电流、间隙状态下的三维静态磁场仿真,对磁场沿工作间隙分布状况进行分析,通过试验台架对制动器性能进行测试。... 详细信息

为提高磁流变制动器制动能效,提出一种多盘连续可变磁流变液工作间隙结构的磁流变制动器。在ANSYS workbench环境下完成不同电流、间隙状态下的三维静态磁场仿真,对磁场沿工作间隙分布状况进行分析,通过试验台架对制动器性能进行测试。结果表明,磁流变液工作区域磁矢量分布相对均匀,无明显积聚现象,磁路设计合理。理论与实验结果变化趋势基本吻合,但在电流较大时,两者之间误差呈逐渐增大趋势。制动力矩在0~2.5 A电流变化区间增速较快,而在2.5~4.0 A区间明显放缓,最大力矩达到146.4 N·m,较间隙未改变状态增加25.80%。设计的制动器TVR值达到48.81 kN·m/m^(3),较传统磁流变制动器结构更紧凑,力矩调节范围更广,设计思路及实验结论对磁流变制动器结构的进一步研究具有借鉴意义。

关键词：磁流变液楔形工作间隙连续可变制动性能

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Chronic hepatitis B virus infection in Eastern Ethiopia:Clinical characteristics and determinants of cirrhosis

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World Journal of Hepatology 2024年第7期16卷 995-1008页

作者： Nejib Y Ismael Semir A Usmael Nega B Belay Hailemichael Desalegn Mekonen Asgeir Johannessen Stian ms Orlien Haramaya University College of Health and Medical SciencesHarar 252Ethiopia Aklilu Lemma Institute of Pathobiology Addis Ababa UniversityAddis Ababa 1000Ethiopia Regional Centre for Imported and Tropical Diseases Oslo University HospitalOslo 0450UllevålNorway Internal Medicine Gastroenterology and Hepatology UnitSaint Paul’s Hospital Millennium Medical CollegeAddis Ababa 1000Ethiopia Department of Infectious Disease Vestfold Hospital TrustTønsberg 3103Norway Institute of Clinical Medicine Oslo UniversityOslo 0318Norway Department of PediatricsOslo UniversityOslo 0450UllevålNorway

BACKGROUND Chronic hepatitis B(CHB)virus infection is a major cause of liver-associated morbidity and mortality,particularly in low-income countries.A better understanding of the epidemiological,clinical,and virological characteristics of CHB will guide appropriate treatment strategies and improve the control and management of CHB in *** To investigate the characteristics of CHB in Eastern Ethiopia and assess the efficacy and safety of antiviral *** This cohort study included 193 adults who were human immunodeficiency virus-negative with CHB between June 2016 and December *** assessments included chemistry,serologic,and viral markers.χ2 tests,Mann-Whitney U tests,and logistic regression analyses were used to identify the determinants of *** disoproxil fumarate(TDF)was initiated using treatment criteria from the Ethiopian CHB pilot *** A total of 132 patients(68.4%)were men,with a median age of 30 years[interquartile range(IQR):24-38].At enrollment,60(31.1%)patients had cirrhosis,of whom 35(58.3%)had decompensated *** use,hepatitis B envelope antigen positivity,and a high viral load were independently associated with ***,66 patients(33.4%)fulfilled the treatment criteria and 59(30.6%)started *** 29 patients who completed 24 months of treatment,the median aspartate aminotransferase to platelet ratio index declined from 1.54(IQR:0.66-2.91)to 1.10(IQR:0.75-2.53)(P=0.002),and viral suppression was achieved in 80.9%and 100%of patients after 12 months and 24 months of treatment,*** the treated patients,12(20.3%)died within the first 6 months of treatment,of whom 8 had decompensated *** This study highlights the high prevalence of cirrhosis,initial mortality,and the efficacy of TDF *** up measures to prevent and control CHB infections in Ethiopia is crucial.

关键词： Chronic hepatitis B Cirrhosis Cohort study Resource-limited settings Sub-Saharan Africa

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Dynamics of 7Li breakup and its influence on elastic scattering: a study of 7Li + 144Sm system

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Chinese Physics C 2024年第2期48卷 124-134页

作者： A.Morzabayev N.Amangeldi Awad A.Ibraheem D.Soldatkhan G.Yergaliuly B.Mauyey anuar.A.Orazalievna Sh.Hamada L.N.Gumilyov eurasian national university astanakazakhstan Institute of nuclear physics almatykazakhstan Physics department king khalid universityabhasaudi arabia Faculty of science tanta universitytantaegypt

The angular distributions of 7Li+144Sm elastic scattering over the energy range of 21.6–52 MeV are reanalyzed utilizing various interaction *** analysis aims to study the consistency of the implemented potentials in representing the considered data and investigate the cluster nature of the weakly bound 7Li *** will aid in the better understanding the impacts of 7Li breakup on the elastic scattering *** coupling to the breakup channel has a substantial impact on the elastic data and reproduces a repulsive dynamical polarization potential,which drastically diminishes the real potential *** reported impact was simulated by introducing a semi-microscopic repulsive DPP and by implementing the method of continuum discretized coupled *** analysis was also extended to understand the impact of triton transfer on the elastic scattering data.

关键词： phenomenological and semi-microscopic potentials cluster folding dynamic polarization

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Prevalence and risk factors of Blastocystis infection among underprivileged communities in rural Malaysia

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Asian Pacific Journal of Tropical Medicine 2017年第5期10卷 467-473页

作者： Nabilah Amelia Mohammad Hesham M.Al-Mekhlafi Norhayati Moktar Tengku shahrul anuar Centre of Medical Laboratory Technology Faculty of Health SciencesUniversiti Teknologi MARAPuncak Alam Campus Endemic and Tropical Disease Unit Medical Research CenterJazan University Department of Parasitology Faculty of Medicine and Health SciencesSana’a University Department of Pre-Clinical Sciences Faculty of Medicine and Health SciencesUniversiti Tunku Abdul RahmanSungai Long Campus Integrative Pharmacogenomics Institute Universiti Teknologi MARAPuncak Alam Campus

Objective:To determine the prevalence and risk factors of Blastocystis among underprivileged communities living in rural Malaysia. Methods:This cross-sectional study was conducted among 253 participants aged between 1 and 85 years. Stool samples were examined using Wheatley's trichrome stain after in-vitro cultivation in Jones' medium to detect the presence of Blastocystis. Information pertaining to the demography,socioeconomic and environment were collected using pre-validated questionnaires. Results:The total prevalence of Blastocystis infection was 40.7%. The multiple logistic regression analysis revealed that age ≥15 years(OR = 2.72; 95%CI = 1.47-5.04) and presence of infected family members(OR = 8.56; 95%CI = 4.47-16.38) were the significant risk factors associated with blastocystosis in these communities. Conclusions:Blastocystosis is revealed through this study to be still prevalent among Orang Asli communities in rural Malaysia. The two main approaches that should be implemented by the public health authority in battling this infection would be the screening of other family members and giving treatment to the infected individuals. Moreover,it is imperative for health education on good personal and food hygiene practices are provided in order to reduce the morbidity and transmission of Blastocystis infection among the Orang Asli in their communities meaningfully.

关键词： Blastocystis Prevalence Risk factors Malaysia

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Developing Engagement in the Learning Management System Supported by Learning Analytics

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Computer Systems Science & Engineering 2022年第7期42卷 335-350页

作者： Suraya Hamid shahrul Nizam Ismail Muzaffar Hamzah Asad W.Malik Department of Information System Faculty of Computer Science and Information TechnologyUniversiti MalayaKuala LumpurMalaysia Faculty of Computing and Informatics Universiti Malaysia SabahSabahMalaysia Department of Computing School of Electrical Engineering and Computer Science(SEECS)National University of Sciences and Technology(NUST)IslamabadPakistan

Learning analytics is an emerging technique of analysing student par-ticipation and *** recent COVID-19 pandemic has signiﬁcantly increased the role of learning management systems(Lmss).Lmss previously only complemented face-to-face teaching,something which has not been possible between 2019 to *** date,the existing body of literature on Lmss has not analysed learning in the context of the pandemic,where an Lms serves as the only interface between students and ***,productive results will remain elusive if the key factors that contribute towards engaging students in learning are notﬁrst identiﬁ***,this study aimed to perform an exten-sive literature review with which to design and develop a student engagement model for holistic involvement in an *** required data was collected from an Lms that is currently utilised by a local Malaysian *** model was validated by a panel of experts as well as discussions with *** is our hope that the result of this study will help other institutions of higher learning determine factors of low engagement in their respective Lmss.

关键词： Engagement analysis learning analytics learning management system student engagement

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高特异性σ2R/TMEM97配体FEM-1689可减轻神经病理性疼痛并抑制整合应激反应

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中国疼痛医学杂志 2024年第3期30卷 161-165页

作者：龙沙沙(译) 韩清见(校) 复旦大学脑科学研究院

在药理学界,σ2受体(σ2R)早在30多年前就被描述过,但其分子特征仍模糊不清,直到最近才被确认为跨膜蛋白97 (TMEM97)。经研究证明σ_(2)R/TMEM97配体可减轻小鼠神经病理性疼痛模型的机械超敏反应,其最大抗痛作用的时间为给药后24 h。该... 详细信息

在药理学界,σ2受体(σ2R)早在30多年前就被描述过,但其分子特征仍模糊不清,直到最近才被确认为跨膜蛋白97 (TMEM97)。经研究证明σ_(2)R/TMEM97配体可减轻小鼠神经病理性疼痛模型的机械超敏反应,其最大抗痛作用的时间为给药后24 h。该研究试图通过解决2个关键问题来了解其抗神经病理性疼痛效应:σ_(2)R/TMEM97化合物是否通过受体选择性地发挥作用,以及它们对痛觉神经元的下游机制是什么?该研究使用了一种Tmem97全身基因敲除小鼠,发现σ_(2)R/TMEM97结合化合物FEM-1689,需要该基因才能在小鼠神经损伤模型中产生抗痛作用。利用小鼠背根神经节原代神经元证明,FEM-1689能抑制整合应激反应(ISR),并通过σ_(2)R/TMEM97特异性作用促进神经元生长。随后,该研究扩展了其临床转化价值,证明FEM-1689可降低人类感觉神经元中的整合应激反应(ISR)和p-eIF2α水平,并可减轻甲基乙二醛对ISR的致病作用。同时,研究还证明了σ_(2)R/TMEM97在人类痛觉感受器和卫星胶质细胞中均有表达。这些结果证实了σ_(2)R/TMEM97有希望成为治疗神经病理性疼痛的靶点。

关键词：抗痛作用特异性作用受体选择性痛觉感受器甲基乙二醛神经病理性疼痛痛觉神经高特异性

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Impact of seasonality on the prevalence and risk factors of Giardia lamblia infections among the aborigines

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Asian Pacific Journal of Tropical Medicine 2019年第7期12卷 315-320页

作者： Samseh Abdullah Noradilah Norhayati Moktar Ii Li Lee Fatmah Md Salleh Tengku shahrul anuar Department of Medical Sciences II Faculty of Medicine and Health SciencesUniversiti Sains Islam MalaysiaPandan Indah55100 Kuala LumpurMalaysia Department of Pre-Clinical Sciences Faculty of Medicine and Health SciencesUniversiti Tunku Abdul RahmanSungai Long CampusSelangorMalaysia Kulliyyah of Medicine and Health Sciences Sultan Abdul Halim Mu'adzam Shah International Islamic UniversityKuala KetilKedahMalaysia Department of Parasitology and Medical Entomology Faculty of MedicineUniversiti Kebangsaan Malaysia Medical CentreCherasKuala LumpurMalaysia Centre of Medical Laboratory Technology Faculty of Health SciencesUniversiti Teknologi MARAPuncak Alam CampusSelangorMalaysia Integrative Pharmacogenomics Institute Universiti Teknologi MARAPuncak Alam CampusSelangorMalaysia

Objective: To determine the prevalence and risk factors of Giardia(G.) lamblia infections among the aboriginal community during the wet and dry seasons. Methods: A total of 473 stool samples from the aborigines in Temerloh, Pahang, Malaysia were collected during wet(n=256) and dry seasons(n=217). Smear of all the PVA-preserved stool samples were subjected to Trichrome staining and microscopic examination under 1 000 伊magnification(Nikon eclipse E100) for the detection of G. lamblia. Positivity was recorded based on the presence of G. lamblia in trophozoite and/or cyst forms. Results: The prevalence of giardiasis was 12.10% and 8.29% during the wet and dry season, respectively. Age of less or equal to 15 years old and presence of other family members with G. lamblia infection were found to be the significant risk factors to acquire G. lamblia infections during both seasons. Untreated water supply was the significant risk factor of giardiasis during the dry season. This study highlighted the possibility of anthroponotic transmission of G. lamblia during both seasons and waterborne transmission during the dry season in the aboriginal community. Conclusions: This study suggests that seasonal variation plays an important role in the prevalence and risk factor of G. lamblia infection in the aboriginal community. Therefore, close contact with Giardia-infected family members and water-related activities or usage of untreated water must be avoided to reduce the burden of G. lamblia infection in this community.

关键词： Giardia Seasonality Aborigine Anthroponotic Waterborne

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The flow behavior of powder stearin-based methyl ester sulfonates and the effect of glidant

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Particuology 2023年第9期80卷 148-156页

作者： Zulina Abd Maurad Luqman Chuah Abdullah Mohd Shamsul anuar Nor Nadiah Abdul Karim Shah Zainab Idris Malaysian Palm Oil Board 6Persiaran InstitusiBandar Baru Bangi43000SelangorMalaysia Department of Chemical and Environmental Engineering Faculty of EngineeringUniversiti Putra MalaysiaSerdangSelangor43400Malaysia Department of Process and Food Technology Faculty of EngineeringUniversiti Putra MalaysiaSerdangSelangor43400Malaysia

The preparation and behavior of powder stearin-based methyl ester sulfonates(MES)with the addition of builder as a glidant agent was *** is an anionic surfactant and its performance is equivalent to petroleum-based linear alkylbenzene sulfonates(LAS),the workhorses of the detergent *** the same time,zeolites or soda ash were the alternative builders for non-phosphate-based *** behavior of powder MES properties was measured in terms of morphology,particle size,cohesion,caking,and *** that,these palm stearin-based MES of carbon chain 16–18 with ratios of 98:2,80:20,and 60:40 in flakes were ground using a high shear mixer by 23,000 rpm to produce powder *** the particle size of MES powder can reduce the powder's cohesion,caking,and *** addition of zeolite or soda ash as a glidant in powdered MES can improve the caking *** high stearic in MES greatly influenced getting fine particle powders and required more glidant *** powder MES with excellent powder characteristics can perform well as a bio-based cleaning product.

关键词： Methyl ester sulfonates Caking Compaction Cohesion Glidant

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