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CNN Channel Attention Intrusion Detection SystemUsing NSL-KDD Dataset

Computers, Materials & Continua 2024年第6期79卷 4319-4347页

作者： Fatma S.Alrayes Mohammed Zakariah Syed Umar Amin Zafar iqbal Khan Jehad Saad Alqurni Information Systems Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia College of Computer and Information Sciences King Saud UniversityRiyadh11362Saudi Arabia College of Computer and Information Sciences Prince Sultan UniversityRiyadh11586Saudi Arabia Department of Educational Technologies College of EducationImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia

Intrusion detection systems(IDS)are essential in the field of cybersecurity because they protect networks from a wide range of online *** goal of this research is to meet the urgent need for small-footprint,highly-adaptable Network Intrusion Detection Systems(NIDS)that can identify *** NSL-KDD dataset is used in the study;it is a sizable collection comprising 43 variables with the label’s“attack”and“level.”It proposes a novel approach to intrusion detection based on the combination of channel attention and convolutional neural networks(CNN).Furthermore,this dataset makes it easier to conduct a thorough assessment of the suggested intrusion detection ***,maintaining operating efficiency while improving detection accuracy is the primary goal of this ***,typical NIDS examines both risky and typical behavior using a variety of *** the NSL-KDD dataset,our CNN-based approach achieves an astounding 99.728%accuracy rate when paired with channel *** to previous approaches such as ensemble learning,CNN,RBM(Boltzmann machine),ANN,hybrid auto-encoders with CNN,MCNN,and ANN,and adaptive algorithms,our solution significantly improves intrusion detection ***,the results highlight the effectiveness of our suggested method in improving intrusion detection precision,signifying a noteworthy advancement in this *** efforts will focus on strengthening and expanding our approach in order to counteract growing cyberthreats and adjust to changing network circumstances.

关键词： Intrusion detection system(IDS) NSL-KDD dataset deep-learning machine-learning CNN channel Attention network security

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A comparative in vitro study on the effect of SGLT2 inhibitors on chemosensitivity to doxorubicin in MCF-7 breast cancer cells

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Oncology Research 2024年第5期32卷 817-830页

作者： shahid KARIM ALANOUD NAHER ALGHANMI MAHA JAMAL HUDA ALKREATHY ALAM JAMAL HIND A.ALKHATABI MOHAMMED BAZUHAIR AFTAB AHMAD Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Biochemistry Faculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia Department of Biochemistry College of ScienceUniversity of JeddahJeddah21959Saudi Arabia Health Information Technology Department The Applied CollegeKing Abdulaziz UniversityJeddahSaudi Arabia Pharmacovigilance and Medication Safety Unit Center of Research Excellence for Drug Research and Pharmaceutical IndustriesKing Abdulaziz UniversityJeddahSaudi Arabia

Cancer frequently develops resistance to the majority of chemotherapy *** study aimed to examine the synergistic cytotoxic and antitumor effects of SGLT2 inhibitors,specifically Canagliflozin(CAN),Dapagliflozin(DAP),Empagliflozin(EMP),and Doxorubicin(DOX),using in vitro *** precise combination of CAN+DOX has been found to greatly enhance the cytotoxic effects of doxorubicin(DOX)in MCF-7 ***,it was shown that cancer cells exhibit an increased demand for glucose and ATP in order to support their ***,when these medications were combined with DOX,there was a considerable inhibition of glucose consumption,as well as reductions in intracellular ATP and lactate ***,this effect was found to be dependent on the dosages of the *** addition to effectively inhibiting the cell cycle,the combination of CAN+DOX induces substantial modifications in both cell cycle and apoptotic gene *** work represents the initial report on the beneficial impact of SGLT2 inhibitor medications,namely CAN,DAP,and EMP,on the responsiveness to the anticancer properties of *** underlying molecular mechanisms potentially involve the suppression of the function of SGLT2.

关键词： SGLT2 Cancer Cytotoxicity ATP Cell cycle

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Enhancing Secure Development in Globally Distributed Software Product Lines: A Machine Learning-Powered Framework for Cyber-Resilient Ecosystems

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Computers, Materials & Continua 2024年第6期79卷 5031-5049页

作者： Marya iqbal Yaser Hafeez Nabil Almashfi Amjad Alsirhani Faeiz Alserhani Sadia Ali Mamoona Humayun Muhammad Jamal University Institute of Information Technology PMAS-Arid Agriculture UniversityRawalpindiPakistan Department of Software Engineering College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia Department of Computer Science College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia Department of Computer Engineering&Networks College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia Department of Information Systems College of Computer and Information SciencesJouf UniversitySakakaAl Jouf72388Saudi Arabia Department of Mathematics Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindiPakistan

Embracing software product lines(SPLs)is pivotal in the dynamic landscape of contemporary software ***,the flexibility and global distribution inherent in modern systems pose significant challenges to managing SPL variability,underscoring the critical importance of robust cybersecurity *** paper advocates for leveraging machine learning(ML)to address variability management issues and fortify the security of *** the context of the broader special issue theme on innovative cybersecurity approaches,our proposed ML-based framework offers an interdisciplinary perspective,blending insights from computing,social sciences,and ***,it employs ML for demand analysis,dynamic feature extraction,and enhanced feature selection in distributed settings,contributing to cyber-resilient *** experiments demonstrate the framework’s superiority,emphasizing its potential to boost productivity and security in *** digital threats evolve,this research catalyzes interdisciplinary collaborations,aligning with the special issue’s goal of breaking down academic barriers to strengthen digital ecosystems against sophisticated attacks while upholding ethics,privacy,and human values.

关键词： Machine Learning variability management cybersecurity digital ecosystems cyber-resilience

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Probing the Efficiency of PPMG-Based Composite Electrolytes for Applications of Proton Exchange Membrane Fuel Cell

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Transactions of Tianjin University 2024年第3期30卷 262-283页

作者： Shakeel Ahmed Faizah Altaf Safyan Akram Khan Sumaira Manzoor Aziz Ahmad Muhammad Mansha shahid Ali Ata-ur-Rehman Karl Jacob School of Material Science and Engineering Henan International Joint Laboratory of Nano-Photoelectric Magnetic MaterialsHenan University of TechnologyZhengzhou 450001China Interdisciplinary Research Center for Hydrogen Technologies and Carbon Management King Fahd University of Petroleum and Minerals31261 DhahranSaudi Arabia School of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGA 30332USA

PPMG-based composite electrolytes were fabricated via the solution method using the polyvinyl alcohol and polyvinylpyrrolidone blend reinforced with various contents of sulfonated inorganic *** acid was employed as the sulfonating agent to functionalize the external surface of the inorganic filler,i.e.,graphene *** proton conductivities of the newly prepared proton exchange membranes(PEMs)were increased by increasing the temperature and content of sulfonated graphene oxide(SGO),i.e.,ranging from 0.025 S/cm to 0.060 S/*** induction of the optimum level of SGO is determined to be an excellent route to enhance ionic *** single-cell performance test was conducted by sandwiching the newly prepared PEMs between an anode(0.2 mg/cm^(2) Pt/Ru)and a cathode(0.2 mg/cm^(2) Pt)to prepare membrane electrode assemblies,followed by hot pressing under a pressure of approximately 100 kg/cm^(2) at 60℃for 5–10 *** highest power densities achieved with PPMG PEMs were 14.9 and 35.60 mW/cm^(2) at 25℃and 70℃,respectively,at ambient pressure with 100%relative *** showed that the newly prepared PEMs exhibit good electrochemical *** results indicated that the prepared composite membrane with 6 wt%filler can be used as an alternative membrane for applications of high-performance proton exchange membrane fuel cell.

关键词： Proton exchange membrane fuel cell Sulfonated graphene oxide Polyvinylpyrrolidone Solution casting Membrane electrode assembly Fuel cell performance

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Retroperitoneal bronchogenic cyst:A case report and review of literature

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World Journal of Clinical Cases 2024年第15期12卷 2586-2596页

作者： Abdul Malik Qais Ahmad Naseer Muhammad Asad iqbal Shi-Ya Han Sheng-Chun Dang Department of General Surgery The Affiliated Hospital of Jiangsu UniversityZhenjiang 212001Jiangsu ProvinceChina Department of Preventive Medicine and Public Health Laboratory Science School of MedicineJiangsu UniversityZhenjiang 212013Jiangsu ProvinceChina Department of Laboratory Medicine School of MedicineJiangsu UniversityZhenjiang 212013Jiangsu ProvinceChina Department of Clinical Pharmacy Shenyang Pharmaceutical UniversityShenyang 110000Liaoning ProvinceChina Department of Surgery Siyang HospitalSuqian 223700Jiangsu ProvinceChina

BACKGROUND Bronchogenic cysts are rare developmental anomalies that belong to the category of congenital enterogenous *** arise from lung buds and are present at *** embryonic foregut is their ***,they are located within the chest cavity,particularly in the cavum mediastinale of the thoracic cavity or lodged in the pulmonary parenchyma,and are considered a type of lung bud *** SUMMARY A 49-year-old male patient was admitted to the hospital due to the detection of a retroperitoneal mass during a physical *** weeks before admission,the patient underwent a physical examination and routine laboratory tests,which revealed a space-occupying mass in the retroperitoneal *** patient did not report any symptoms(such as abdominal pain,flatulence,nausea,vomiting,high fever,or chills).The computed tomography(CT)revealed a retroperitoneal spaceoccupying lesion with minimal enhancement and a CT value of approximately 36 Hounsfield *** lesion was not delineated from the boundary of the pancreatic body and was closely related to the retroperitoneum *** Following a series of tests,an abdominal mass was identified,prompting the implementation of a laparoscopic retroperitoneal mass excision *** the investigation,an 8 cm×7 cm cystic round-shaped mass with a distinct demarcation was identified in the upper posterior region of the ***,full resection of the mass was *** pathological examination reveled a cystic mass characterized by a smooth inner *** cystic mass was found to contain a white,viscous liquid within its capsule.

关键词： Bronchogenic cyst Retroperitoneal space Excision Laparoscopic surgery Case report

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Geraniol alleviates cyclophosphamide-induced cardiotoxicity in mice

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Asian Pacific Journal of Tropical Biomedicine 2024年第10期14卷 427-435页

作者： shahid Karim Rasheed A.Shaik Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Pharmacology and Toxicology Faculty of PharmacyKing Abdulaziz UniversityJeddahSaudi Arabia

Objective:To explore the effect of geraniol on cyclophosphamide-induced ***:Mice were divided into five groups:the control group,the cyclophosphamide group(200 mg/kg cyclophosphamide,*** day 7),the group treated with geraniol 100 and 200 mg/kg from day 1 to day 14,along with a single dose of cyclophosphamide on day 7,and the geraniol alone group(200 mg/kg geraniol from day 1 to day 14).At the end of the study,animals were sacrificed,and blood and heart were collected and analyzed for biochemical,histopathological,and immunohistochemical ***:Treatment with 200 mg/kg geraniol significantly reduced the levels of cardiac injury markers,malondialdehyde,and inflammatory and apoptotic markers,while increasing antioxidant activities in mice with cyclophosphamide-induced ***,it remarkably alleviated histopathological aberrations in cardiac ***:Geraniol attenuates cyclophosphamide-induced cardiotoxicity via antioxidant,anti-inflammatory,and antiapoptotic effects.

关键词： Geraniol Cardiotoxicity Natural product Cyclophosphamide Inflammation Apoptosis

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Modelling of debris-flow susceptibility and propagation: a case study from Northwest Himalaya

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Journal of Mountain Science 2024年第1期21卷 200-217页

作者： Hamza DAUD Javed iqbal TANOLI Sardar Muhammad ASIF Muhammad QASIM Muhammad ALI Junaid KHAN Zahid Imran BHATTI Ishtiaq Ahmad Khan JADOON Badong National Observation and Research Station of Geohazards China University of GeosciencesWuhan 430074China Department of Earth Sciences COMSATS University IslamabadAbbottabad Campus 22010Pakistan Department of Earth Sciences Sultan Qaboos UniversityAl-KhoudMascat 123Oman Faculty of Engineering China University of Geosciences(Wuhan)Wuhan 430074China Department of Earth Sciences Abbottabad University of Science and TechnologyHavelian 22500Pakistan

The geological and geographical position of the Northwest Himalayas makes it a vulnerable area for mass movements particularly landslides and debris flows. Mass movements have had a substantial impact on the study area which is extending along Karakorum Highway(KKH) from Besham to Chilas. Intense seismicity, deep gorges, steep terrain and extreme climatic events trigger multiple mountain hazards along the KKH, among which debris flow is recognized as the most destructive geohazard. This study aims to prepare a field-based debris flow inventory map at a regional scale along a 200 km stretch from Besham to Chilas. A total of 117 debris flows were identified in the field, and subsequently, a point-based debris-flow inventory and catchment delineation were performed through Arc GIS analysis. Regional scale debris flow susceptibility and propagation maps were prepared using Weighted Overlay Method(WOM) and Flow-R technique sequentially. Predisposing factors include slope, slope aspect, elevation, Topographic Roughness Index(TRI), Topographic Wetness Index(TWI), stream buffer, distance to faults, lithology rainfall, curvature, and collapsed material layer. The dataset was randomly divided into training data(75%) and validation data(25%). Results were validated through the Receiver Operator Characteristics(ROC) curve. Results show that Area Under the Curve(AUC) using WOM model is 79.2%. Flow-R propagation of debris flow shows that the 13.15%, 22.94%, and 63.91% areas are very high, high, and low susceptible to debris flow respectively. The propagation predicated by Flow-R validates the naturally occurring debris flow propagation as observed in the field surveys. The output of this research will provide valuable input to the decision makers for the site selection, designing of the prevention system, and for the protection of current infrastructure.

关键词： North Pakistan Debris flow Flow-R Propagation Susceptibility mapping Debris-flow inventory Weighted Overlay Method

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Coleus forskohlii shows anti-psoriatic activity in imiquimod-induced psoriasis rats

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Asian Pacific Journal of Tropical Biomedicine 2024年第9期14卷 382-390,I0002-I0007页

作者： Sagarika Majhi Iti Chauhan Deepak Kumar Md.Niyaz Alam Md.Sarfaraj Hussain Muzaffar iqbal Faculty of Pharmacy I.T.S College of PharmacyMuradnagarGhaziabadU.P.India Lord Buddha Koshi Pharmacy College of Pharmacy BaijanathpurNH 107Saharsa(Bihar)852201India Department of Pharmaceutical Chemistry College of PharmacyKing Saud UniversityP.O.Box 2457Riyadh 11451Saudi Arabia

Objective:To evaluate anti-psoriatic activity of Coleus forskohlii in rats with imiquimod-induced ***:Imiquimod was used to induce psoriasis in *** weight,skin thickness,erythema,scaling,spleen weight,and histological alternations were measured to assess the effect of Coleus ***,an emulgel formulation containing Coleus forskohlii 10%was prepared and characterized along with its ex vivo permeation ***:The emulgel formulation containing Coleus forskohlii 10%had a pH of 5.40±0.36,with optimum spreadability of(31.67±2.08)g/(cm·s)and viscosity of(15966.67±1274.10)cps,and enhanced both the rate and the extent of drug permeation through psoriatic *** an ex vivo study,the quantity of drug permeated(19.18%),deposited(52.38%),and drug remaining in the donor compartments(28.31%)was *** forskohlii significantly alleviated imiquimod-induced psoriasis by increasing glutathione and superoxide dismutase activity,decreasing malondialdehyde and nitric oxide levels,and alleviating histological alternations in rat ***:Coleus forskohlii can alleviate imiquimod-induced psoriasis,which may be used as a therapeutic candidate for the treatment of psoriasis.

关键词： Psoriasis Coleus forskohlii Emulgel Ex vivo Imiquimod Carbopol

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Construction of robust and durable Cu_(2)Se-V_(2)O_(5) nanosheet electrocatalyst for alkaline oxygen evolution reaction

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Frontiers of Chemical Science and Engineering 2024年第6期18卷 71-83页

作者： Tauseef Munawar Ambreen Bashir Khalid Mujasam Batoo Saman Fatima Faisal Mukhtar Sajjad Hussain Sumaira Manzoor Muhammad Naeem Ashiq Shoukat Alim Khan Muammer Koc Faisal iqbal Institute of Physics The Islamia University of BahawalpurBahawalpur 63100Pakistan King Abdullah Institute for Nanotechnology King Saud UniversityRiyadh 11451Saudi Arabia Hybrid Materials Center(HMC) Sejong UniversitySeoul 05006Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Institute of Chemical Sciences Bahauddin Zakariya UniversityMultan 60800Pakistan Division of Sustainable Development College of Science and EngineeringHamad Bin Khalifa UniversityQatar FoundationDoha 34110Qatar

Reducing the production costs of clean energy carriers such as hydrogen through scalable water electrolysis is a potential solution for advancing the hydrogen *** the various material candidates,our group demonstrated transition-metal-based materials with tunable electronic characteristics,various phases,and ***,electrochemical water oxidation using Cu_(2)Se-V_(2)O_(5) as a non-precious metallic electrocatalyst via a hydrothermal approach is *** water-splitting performance of all the fabricated electrocatalysts was evaluated after direct growth on a stainless-steel *** electrochemically tuned Cu_(2)Se-V_(2)O_(5) catalyst exhibited a reduced overpotential of 128 mV and provided a reduced Tafel slope of 57 mV·dec^(−1) to meet the maximum current density of 250 mA·cm^(−2).The optimized strategy for interfacial coupling of the fabricated Cu_(2)Se-V_(2)O_(5) catalyst resulted in a porous structure with accessible active sites,which enabled adsorption of the intermediates and afforded an effective charge transfer rate for promoting the oxygen evolution ***,the combined effect of the catalyst components provided long-term stability for over 110 h in an alkaline solution,which makes the catalyst promising for large-scale practical *** aforementioned advantages of the composite catalyst overcome the limitations of low conductivity,agglomeration,and poor stability of the pure catalysts(Cu2Se and V2O5).

关键词： oxygen evolution reaction Cu_(2)Se-V_(2)O_(5)composite nanosheets metal-diffused ions accessible adsorption sites

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Anti-Jamming Null Space Projection Beamforming Based on Symbiotic Radio

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工程与科学中的计算机建模(英文) 2024年第1期138卷 679-689页

作者： Baofeng Ji Yifan Liu Tingpeng Li Ling Xing Weixing Wang shahid Mumtaz Xiaolong Shang Wanying Liu Congzheng Han State Key Laboratory of Complex Electromagnetic Environment Effects on Electronics and Information System(CEMEE) Luoyang471000China Research and Innovation Center of Intelligent System Longmen LaboratoryLuoyang471000China College of Information Engineering Henan University of Science and TechnologyLuoyang471000China Institute of Atmospheric Physics Chinese Academy of Sciences(LAGEO)Beijing100000China Instituto de Telecomunicaes Aveiro3800-005Portugal Chinese Academy of Agricultural Mechanization Sciences Beijing100000China

With the development of information technology,more and more devices are connected to the Internet through wireless communication to complete data *** to the broadcast characteristics ofwireless channels,wireless networks have suffered more and more malicious *** layer security has received extensive attention from industry and *** is considered to be one of the most important technologies related to physical layer *** beamforming technology,messages can be transmitted to legitimate users in an offset direction that is as orthogonal as possible to the interference channel to ensure the reception SINR by legitimate *** the symbiotic radio(SR)technology,this paper considers a symbiotic radio antijamming MIMO system equipped with a multi-antenna system at the main base *** order to avoid the interference signal and improve the SINR of the signal received by the *** base station is equipped with a uniform rectangular antenna array,and using Null Space Projection(NSP)Beamforming,Intelligent Reflecting Surface(IRS)can assist in changing the beam’s *** simulation results show that NSP Beamforming could make a better use of the null space of interference,which can effectively improve the received SINR of users under directional interference,and improve the utilization efficiency of signal energy.

关键词： Symbiotic radio anti-jamming MIMO NSP Beamforming physical layer security

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