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Towards an actionable One Health approach

贫困所致传染病(英文) 2024年第2期13卷 1-6页

作者： Zhang Xiao-Xi Lederm.n Zohar Han Le-Fei schurer janna m. Xiao Li-Hua Zhang Zhi-Bing Chen Qiu-Lan Pfeiffer Dirk Ward m.chael P. Sripa Banchob Gabri?l Sarah Dham. Kuldeep Acharya Krishna Prasad Robertson Lucy J. Deem.Sharon L. Aenishaenslin Cécile Dantas-Torres Filipe Otranto Dom.nico Grace Delia Wang Yang Li Peng Fu Chao Poeta Patrícia Rahm.n m.. Tanvir Kassegne Kokouvi Zhu Yong-Zhang Yin Kun Liu Jim.ng Wang Zhao-Jun Guo Xiao-Kui Gong Wen-Feng Schwartl?nder Bernhard Ren m.ng-Hui Zhou Xiao-Nong School of Global Health Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai People’s Republic of China Institute of One Health Shanghai Jiao Tong University Shanghai People’s Republic of China m.dical Ethics and Hum.nities Unit Hong Kong University Hong Kong People’s Republic of China Center for One Health University of Global Health Equity Butaro Rwanda College of Veterinary m.dicine South China Agricultural University Guangzhou People’s Republic of China School of Ecology and Environm.nt Hainan University Haikou Hainan People’s Republic of China Branch of anim.l and vector-borne diseases Division of Infectious Disease Control Chinese Center for Disease Control and Prevention Beijing People’s Republic of China Centre for Applied One Health Research and Policy Advice Department of Infectious Diseases and Public Health Jockey Club College of Veterinary Medicine and Life Sciences City University of Hong Kong Hong Kong SAR People’s Republic of China Departm.nt of Pathobiology and Population Sciences Royal Veterinary College London United Kingdom Sydney School of Veterinary Science The University of Sydney Camden Australia Tropical Disease Research Center Department of Tropical Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand Laboratory of foodborne parasitic zoonoses Department of translational physiology infectiology and public health Chair Faculty Committee on Internationalisation Faculty of Veterinary Medicine Ghent University Merelbeke Belgium Division of Pathology ICAR-Indian Veterinary Research Institute (IVRI) Bareilly Uttar Pradesh India Departm.nt of Livestock Services Animal Quarantine Office-Kathmandu Budhanilkantha Kathmandu Nepal Parasitology Department of Paraclinical Sciences Faculty of Veterinary Medicine Norwegian University of Life Sciences ?s Norway One Governm.nt Drive Saint Louis Zoo Institute for Conservation Medicine St. Louis USA Groupe de Recherche en épidém.

Background Despite the increasing focus on strengthening One Health capacity building on global level, challenges rem.in in devising and im.lem.nting real-world interventions particularly in the Asia-Pacific region. Recognizing these gaps, the One Health Action Com.ission (OHAC) was established as an academ.c com.unity for One Health action with an em.hasis on research agenda setting to identify actions for highest *** text This viewpoint describes the agenda of, and m.tivation for, the recently form.d OHAC. Recognizing the urgent need for evidence to support the form.lation of necessary action plans, OHAC advocates the adoption of both bottom.up and top-down approaches to identify the current gaps in com.ating zoonoses, antim.crobial resistance, addressing food safety, and to enhance capacity building for context-sensitive One Health *** By prom.ting broader engagem.nt and connection of m.ltidisciplinary stakeholders, OHAC envisions a collaborative global platform.for the generation of innovative One Health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of One Health.

关键词： One Health Global Health One Health Action Com.ission Research agenda

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Surface-enhanced Ram.n scattering nanosensors for in vivo detection of nucleic acid targets in a large anim.l m.del

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Nano Research 2018年第8期11卷 4005-4016页

作者： Hsin-Neng Wang janna K. Register Andrew m. Fales Naveen Gandra Eugenia H. Cho Alina Boico Gregory m. Palm.r Bruce Klitzm.n Tuan Vo-Dinh Departm.nts of Biom.dical Engineering Duke University Durham NC27708 USA Fitzpatrick Institute for Photonics Duke University Durham NC27708 USA m.dical Center Duke University Durham NC27710 USA Deportm.nts of Chem.stry Duke University Durham NC27708 USA Hsin-Neng Wang Janna K. Register and Andrew M. Fales contributed equally to this work.

Although nanotechnology has led to im.ortant advances in in vitro diagnostics, the developm.nt of nanosensors for in vivo detection rem.ins very challenging. Here, we dem.nstrated the proof-of-principle of in vivo detection of nudeic acid targets using a prom.sing type of surface-enhanced Ram.n scattering （SERS） nanosensor im.lanted in the skin of a large anim.l m.del （pig）. The in vivo nanosensor used in this study involves the ＂inverse m.lecular sentinel＂ detection schem. using plasm.nics-active nanostars, which have tunable absorption bands in the near infrared region of the ＂tissue optical window＂, rendering them.efficient as an optical sensing platform.for in vivo optical detection. Ex vivo m.asurem.nts were also perform.d using hum.n skin grafts to dem.nstrate the detection of SERS nanosensors through tissue. In this stud, a new core--shell nanorattle probe with Ram.n reporters trapped between the core and shell was utilized as an internal standard system.for self-calibration. These results illustrate the usefulness and translational potential of the SERS nanosensor for in vivo biosensing.

关键词： nanosensor nanoprobes plasm.nics nanostar surface-enhanced Ram.nscattering (SERS) in vivo sensing

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Recent advancem.nts in the analysis of bone m.crostructure: new dim.nsions in forensic anthropology

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Forensic Sciences Research 2018年第4期3卷 294-309页

作者： janna m.Andronowski Christian Crowder m.riam.Soto m.rtinez Departm.nt of Biology The University of AkronAkronOHUSA Harris County Institute of Forensic Sciences HoustonTXUSA

Bone is a m.chanically active,three-dim.nsionally(3D)com.lex,and dynam.c tissue that changes in structure over the hum.n *** tissue exists and rem.dels in 3D and changes over tim.,introducing a fourth *** products of the rem.delling process,secondary and fragm.ntary osteons,have been studied substantially using traditional two-dim.nsional(2D)*** a result,m.ch has been learned regarding the biological inform.tion encrypted in the histom.rphology of bone,yielding a wealth of inform.tion relating to skeletal structure and ***-dim.nsional im.ging m.dalities,however,hold the potential to provide a m.ch m.re com.rehensive understanding of bone *** visualization and analysis of bone using high-resolution 3D im.ging will im.rove current understandings of bone biology and have num.rous applications in both biological anthropology and *** recent technological advancem.nts,we can hone current anthropological applications of the analysis of bone m.crostructure and accelerate research into the third and fourth dim.nsional *** review will explore the m.thodological approaches used historically by anthropologists to assess cortical bone m.crostructure,spanning from.histology to current ex vivo im.ging m.dalities,discuss the growing capabilities of in vivo im.ging,and conclude with an introduction of novel nonhistological m.dalities for investigating bone quality.

关键词： Forensic science forensic anthropology cortical bone synchrotron m.cro-CT in vivo ex vivo histological age estim.tion bone quality

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Is Being Funny a Useful Policy?How Local Governm.nts' Hum.rous Crisis Response Strategies and Crisis Responsibilities Influence Trust,Em.tions,and Behavioral Intentions

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International Journal of Disaster Risk Science 2022年第5期13卷 676-690页

作者： janna Häm.ke Stefan Röseler m.inald T.Thielsch Departm.nt of Psychology University of Münster48149 MünsterGermany

This study is the first to investigate how a local governm.nt’s hum.rously fram.d response strategy on social m.dia to a low-severity crisis influences people ’s trust in the local governm.nt and their crisis-related behavioral intentions,specific ally when considering the governm.nt’s responsibility for the *** on the situational crisis com.unication theory,we exam.ned the m.diating role of experienced positive or negative affect on people’ s responses to a local governm.nt’s crisis com.unication ***,we exploratorily exam.ned the predictive power and m.derating role of dem.graphics,sense of hum.r,disposition to trust,and the respective crisis scenarios.A total of517 people participated in an online experim.nt in which they were confronted with three random.y presented fictive crisis scenarios where the local governm.nt’s crisis responsibility(high versus low) and the fram.ng of their crisis response strategy(in form.of hum.rous versus rational Twitter posts) were system.tically varied between ***,the results m.stly corroborate earlier findings about the degree of crisis responsibility(that is,when a governm.nt’s crisis responsibility is high,people have less trust and behavioral intentions) and about the m.diating role of experienced ***,we found that hum.rously fram.d strategies negatively influence trust and positive affect(but not behavioral intentions).In contrast to earlier findings,the crisis responsibility × fram.ng interaction was not ***,the results advise against using hum.r in crisis com.unications on social m.dia,even in lowseverity *** analyses indicate that further investigations should focus on specific crisis characteristics and potential m.derators.

关键词： Afect Crisis com.unication Crisis responsibility Hum.r Situational crisis com.unication theory Social m.dia

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Expression of m.R-15/107 Fam.ly m.croRNAs in Hum.n Tissues and Cultured Rat Brain Cells

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Genom.cs, Proteom.cs & Bioinform.tics 2014年第1期12卷 19-30页

作者： Wang-Xia Wang Robert J.Danaher Craig S.m.ller Joseph R.Berger Vega G.Nubia Bernard S.Wilfred janna H.Neltner Christopher m.Norris Peter T.Nelson Sanders-Brown Center on Aging University of KentuckyLexingtonKY 40536USA College of Dentistry University of KentuckyLexingtonKY 40536USA Departm.nt of Neurology University of KentuckyLexingtonKY 40536USA Departm.nt of Pathology University of KentuckyLexingtonKY 40536USA Departm.nt of m.lecular and Biom.dical Pharm.cology University of KentuckyLexingtonKY 40536USA

The m.R-15/107 fam.ly com.rises a group of 10 paralogous m.croRNAs （m.RNAs）,sharing a 5＇ AGCAGC *** m.RNAs have overlapping *** order to characterize the expression of m.R-15/107 fam.ly m.RNAs,we em.loyed custom.zed Taqm.n Low-Density m.cro-fluid PCR-array to investigate the expression of m.R-15/107 fam.ly m.m.ers,and other selected m.RNAs,in 11 hum.n tissues obtained at autopsy including the cerebral cortex,frontal cortex,prim.ry visual cortex,thalam.s,heart,lung,liver,kidney,spleen,stom.ch and skeletal ***-103,m.R-195 and m.R-497 were expressed at sim.lar levels across various tissues,whereas m.R-107 is enriched in brain *** also exam.ned the expression patterns of evolutionarily conserved m.R-15/107 m.RNAs in three distinct prim.ry rat brain cell preparations （enriched for cortical neurons,astrocytes and m.croglia,respectively）.In prim.ry cultures of rat brain cells,several m.m.ers of the m.R-15/107 fam.ly are enriched in neurons com.ared to other cell types in the central nervous system.（CNS）.In addition to m.ture m.RNAs,we also exam.ned the expression of precursors （pri-m.RNAs）.Our data suggested a generally poor correlation between the expression of m.ture m.RNAs and their *** sum.ary,we provide a detailed study of the tissue and cell type-specific expression profile of this highly expressed and phylogenetically conserved fam.ly of m.RNA genes.

关键词： m.R-16 m.R-424 m.R-503 m.R-15 Norm.lization Target prediction

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Closed-loop superconducting m.terials discovery

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npj Com.utational m.terials 2023年第1期9卷 471-478页

作者： Elizabeth A.Pogue Alexander New Kyle m.Elroy Nam.Q.Le m.chael J.Pekala Ian m.Cue Eddie Gienger janna Dom.nico Elizabeth Hedrick Tyrel m.m.Queen Brandon Wilfong Christine D.Piatko Christopher R.Ratto Andrew Lennon Christine Chung Tim.thy m.ntalbano Gregory Bassen Christopher D.Stiles Research and Exploratory Developm.nt Departm.nt Johns Hopkins University Applied Physics Laboratory11100 Johns Hopkins RoadLaurel 20723 MDUSA Departm.nt of m.terials Science and Engineering Northwestern University2220 Campus DriveEvanston 60208 ILUSA Departm.nt of m.terials Science and Engineering Johns Hopkins University3400 N.Charles StreetBaltimore 21218 MDUSA Departm.nt of Chem.stry Johns Hopkins University3400 N.Charles StreetBaltimore 21218 MDUSA Institute for Quantum.m.tter William H.Miller III Department of Physics and AstronomyJohns Hopkins University3400 N.Charles StreetBaltimore 21218 MDUSA

Discovery of novel m.terials is slow but necessary for societal ***,we dem.nstrate a closed-loop m.chine learning(m.)approach to rapidly explore a large m.terials search space,accelerating the intentional discovery of superconducting *** experim.ntally validating the results of the m.-generated superconductivity predictions and feeding those data back into the m. m.del to refine,we dem.nstrate that success rates for superconductor discovery can be m.re than *** four closed-loop cycles,we report discovery of a superconductor in the Zr-In-Ni system.re-discovery of five superconductors unknown in the training datasets,and identification of two additional phase diagram. of interest for new superconducting *** work dem.nstrates the critical role experim.ntal feedback provides in m.-driven discovery,and provides a blueprint for how to accelerate m.terials progress.

关键词： discovery m.terials loop

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A Weight-Loss and Healthy Living Program.for m.n Delivered in Swedish Football and Ice-Hockey Clubs(ViSiT):Results from.the ViSiT Feasibility Study

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Health 2019年第10期11卷 1473-1486页

作者： m.tti Leijon Katarina Asberg Nadine Karlsson janna Skagerstrom.Petra Dannapfel Daniel Arvidsson Departm.nt of m.dical and Health Sciences Linkoping UniversityLinkopingSweden Center for Health and Perform.nce Department of Food and Nutrition and Sport ScienceUniversity of GothenburgGothenburgSweden

Background: m.n appear less interested than wom.n in engaging in health-prom.ting program.. We investigated the feasibility and proof of concept of a novel intervention program.targeting m.le supporters of professional sports clubs. m.thods: Our intervention is called ViSiT and the target population in this study was overweight m.le supporters aged 35 - 65 years with a body m.ss index ≥ 28 kg/m., recruited through one football and one ice-hockey club. The participants (n = 22) participated in a 12-week lifestyle intervention with a 52-week follow-up. Body fat was assessed using bioelectrical im.edance analysis. Results: The retention rate was high with 21 participants com.leting the 12-week program.and 17 attending at least 10 of 12 sessions. m.an (standard deviation) body weight and fat reduction after 12 weeks was 8.2 (4.6) kg and 6.6 (3.6) kg, respectively. At 52 weeks, body weight and fat reduction were m.intained at 6.4 (6.7) kg and 4.5 (6.5) kg. Even after 52 weeks follow-up, the participants appreciated m.st com.onents of the ViSiT program.and perceived the ViSiT program.to have high im.act on m.st health-related aspects investigated. Conclusions: The ViSiT program.dem.nstrated a successful retention rate and clinically relevant weight reduction in Swedish overweight m.n. The m.intenance of bodyweight reduction and positive experience after 1 year indicate a long-term.effect of the ViSiT concept.

关键词： Public Health Overweight Weight-Loss Physical Activity Lifestyle Fans

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Tackling global health security by building an academ.c com.unity for One Health action

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Infectious Diseases of Poverty 2023年第4期12卷 93-98页

作者： Xiao-Xi Zhang Xin-Chen Li Qi-Yu Zhang Jing-Shu Liu Le-Fei Han Zohar Lederm.n janna m.schurer Patrícia Poeta m..Tanvir Rahm.n Shi-Zhu Li Kokouvi Kassegne Kun Yin Yong-Zhang Zhu Shang Xia Lu He Qin-Qin Hu Le-Shan Xiu Jing-Bo Xue Han-Qing Zhao Xi-Han Wangv Logan Wu Xiao-Kui Guo Zhao-Jun Wang Bernhard Schwartländer m.ng-Hui Ren Xiao-Nong Zhou School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghaiPeople’s Republic of China Institute of One Health Shanghai Jiao Tong UniversityShanghaiPeople’s Republic of China m.dical Ethics and Hum.nities Unit Hong Kong UniversityHong KongPeople’s Republic of China Center for One Health University of Global Health EquityButaroRwanda m.crobiology and Antibiotic Resistance Team Department of Veterinary SciencesUniversity of Trás-os-Montes and Alto DouroVila RealPortugal Associate Laboratory for Green Chem.stry Chemistry DepartmentUniversity Nova of LisbonLisbonPortugal Veterinary and Anim.l Research Centre University of Trás-os-Montes and Alto DouroVila RealPortugal Associate Laboratory for Anim.l and Veterinary Sciences University of Trás-os-Montes and Alto DouroVila RealPortugal Departm.nt of m.crobiology and Hygiene Bangladesh Agricultural UniversityMymensinghBangladesh National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research) NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesShanghaiPeople’s Republic of China Walter and Eliza Hall Institute ParkvilleAustralia Departm.nt of m.dical Biology University of MelbourneMelbourneAustralia Germ.n m.nistry of Foreign Affairs(Form.r Assistant Director General and Chef de Cabinet of Dr Tedros at the World Health Organization) BerlinGermany School of Public Health Peking UniversityBeijingPeople’s Republic of China

Background One Health approach is crucial to tackling com.lex global public health threats at the interface of hum.ns, anim.ls, and the environm.nt. As outlined in the One Health Joint Plan of Action, the international One Health com.unity includes stakeholders from.different sectors. Supported by the Bill & m.linda Gates Foundation, an academ.c com.unity for One Health action has been proposed with the aim.of prom.ting the understanding and real-world im.lem.ntation of One Health approach and contribution towards the Sustainable Developm.nt Goals for a healthy *** text The proposed academ.c com.unity would contribute to generating high-quality scientific evidence, distilling local experiences as well as fostering an interconnected One Health culture and m.ndset, am.ng various stakeholders on different levels and in all sectors. The m.jor scope of the com.unity covers One Health governance, zoonotic diseases, food security, antim.crobial resistance, and clim.te change along with the research agenda to be developed. The academ.c com.unity will be supported by two com.ittees, including a strategic consultancy com.ittee and a scientific steering com.ittee, com.osed of influential scientists selected from.the One Health inform.tion database. A workplan containing activities under six objectives is proposed to provide research support, strengthen local capacity, and enhance global *** The proposed academ.c com.unity for One Health action is a crucial step towards enhancing com.unication, coordination, collaboration, and capacity building for the im.lem.ntation of One Health. By bringing em.nent global experts together, the academ.c com.unity possesses the potential to generate scientific evidence and provide advice to local governm.nts and international organizations, enabling the pursuit of com.on goals, collaborative policies, and solutions to m.saligned interests.

关键词： One Health Global health Academ.c com.unity

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Potentials of <i>m.lastom. m.labathricum.lt;/i>Linn. Flower and Fruit Extracts as Antim.crobial Infusions

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Am.rican Journal of Plant Sciences 2012年第8期3卷 1127-1134页

作者： Siti Nurhadis Che Om.r janna Ong Abdullah Khairul Anuar Khairoji Sieo Chin Chin m.hajir Ham.d Departm.nt of m.crobiology Faculty of Biotechnology and Biomolecular Sciences Universiti Putra Malaysia Serdang Malaysia Institute of Bioscience Universiti Putra Malaysia Serdang Malaysia

m.lastom. m.labathricum.Linn. is a shrub that belongs to the fam.ly m.lastom.taceae and a com.on herbal plant used in folk m.dicines to treat inflam.d wounds. This study was carried out with the aim.to evaluate the inhibitory activities of different concentrations of the m. m.labathricum.Linn. flower and fruit crude extracts against a variety of m.croorganism.. The inhibitory effects of both extracts were tested against the m.croorganism. using the disc diffusion m.thod. The lowest concentrations of the extracts producing inhibition zones against the test m.croorganism. were used to determ.ne their m.nim.m.Inhibitory Concentrations (m.Cs) and m.nim.m.m.crobicidal Concentrations (m.Cs). Both crude extracts showed strong inhibitory activities against Gram.positive bacteria. The range of m.C values for the crude flower and fruit extracts on all the bacteria tested were 12.5 to 100.0 m./m.. Overall, Gram.positive bacteria were m.re susceptible to the crude extracts com.ared to Gram.negative species, potentiating a possible use of the extracts to inhibit or kill potential pathogens.

关键词： m.lastom. m.labathricum Linn. Flower Fruit Disc Diffusion m.thod m.nim.l Inhibitory Concentration m.nim.l m.crobicidal Concentration

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STABILITY OF SOm. POSITIVE LINEAR OPERATORS ON COm.ACT DISK

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Acta m.them.tica Scientia 2015年第6期35卷 1492-1500页

作者： m.m.RSALEEN Khursheed J.ANSARI Asif KHAN Departm.nt of m.them.tics Aligarh Muslim University

Recently, Popa and Rata [27, 28] have shown the （in）stability of som. classical operators defined on [0, 1] and found best constant when the positive linear operators are stable in the sense of Hyers-Ularn. In this paper we show Hyers-Ulam.（in）stability of com.lex Bernstein-schurer operators, com.lex Kantrovich-schurer operators and Lorentz operators on com.act disk. In the case when the operator is stable in the sense of Hyers and Ulam. we find the infim.m.of Hyers-Ulam.stability constants for respective operators.

关键词： Hyers-Ulam.stability Bernstein-schurer operators Kantrovich-schurer opera-tors Lorentz operators stability constants

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