Potentials of <i>Melastoma malabathricum</i>Linn. Flower and Fruit Extracts as Antimicrobial Infusions
Potentials of <i>Melastoma malabathricum</i>Linn. Flower and Fruit Extracts as Antimicrobial Infusions作者机构：Department of Microbiology Faculty of Biotechnology and Biomolecular Sciences Universiti Putra Malaysia Serdang Malaysia Institute of Bioscience Universiti Putra Malaysia Serdang Malaysia
出 版 物：《American Journal of Plant Sciences》 (美国植物学期刊（英文）)
年 卷 期：2012年第3卷第8期
页 面：1127-1134页
学科分类：1006[医学-中西医结合] 1005[医学-中医学] 10[医学]
主 题：Melastoma malabathricum Linn. Flower Fruit Disc Diffusion Method Minimal Inhibitory Concentration Minimal Microbicidal Concentration
摘 要：Melastoma malabathricum Linn. is a shrub that belongs to the family Melastomataceae and a common herbal plant used in folk medicines to treat inflamed wounds. This study was carried out with the aim to evaluate the inhibitory activities of different concentrations of the M. malabathricum Linn. flower and fruit crude extracts against a variety of microorganisms. The inhibitory effects of both extracts were tested against the microorganisms using the disc diffusion method. The lowest concentrations of the extracts producing inhibition zones against the test microorganisms were used to determine their Minimum Inhibitory Concentrations (MICs) and Minimum Microbicidal Concentrations (MMCs). Both crude extracts showed strong inhibitory activities against Gram-positive bacteria. The range of MIC values for the crude flower and fruit extracts on all the bacteria tested were 12.5 to 100.0 mg/ml. Overall, Gram-positive bacteria were more susceptible to the crude extracts compared to Gram-negative species, potentiating a possible use of the extracts to inhibit or kill potential pathogens.
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