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Can endoscopic submucosal dissection be safely performed in a smaller specialized clinic?

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World Journal of Gastroenterology 2013年第4期19卷 528-535页

作者： Naondo Sohara satoshi Hagiwara Riki Arai Haruhisa iizuka Yasuhiro Onozato Satoru Kakizaki Department of Endoscopy and Endoscopic Surgery Shirakawa ClinicMaebashiGunma 371-0051Japan Department of Medicine and Molecular Science Gunma University Graduate School of MedicineMaebashiGunma 371-8511Japan

AIM:To investigate whether endoscopic submucosal dissection(ESD) can be safely performed at small clinics,such as the Shirakawa ***:One thousand forty-seven ESDs to treat gastrointestinal tumors were performed at the Shirakawa Clinic from April 2006 to March *** efficacy,technical feasibility and associated complications of the procedures were *** ESD procedures were performed by five *** was induced with propofol for esophagogastorduodenal ***:One thousand forty-seven ESDs were performed to treat 64 patients with esophageal cancer(E),850 patients with gastric tumors(G:764 patients with cancer,82 patients with adenomas and four others),four patients with duodenal cancer(D) and 129 patients with colorectal tumors(C:94 patients with cancer,21 patients with adenomas and 14 others).The en bloc resection rate was 94.3%(E:96.9%,G:95.8%,D:100%,C:79.8%).The median operation time was 46 min(range:4-360 min) and the mean size of the resected specimens was 18 mm(range:2-150 mm).No mortal complications were observed in association with the ESD *** occurred in 12 cases(1.1%,E:1 case,G:9 cases,D:1 case,C:1 case) and postoperative bleeding occurred in 53 cases(5.1%,G:51 cases,D:1 case,C:1 case);however,no case required either emergency surgery or blood *** of the perforations and postperative bleedings were resolved by endoscopic clipping or *** other problematic complication observed was pneumonia,which was treated with conservative ***:ESD can be safely performed in a clinic with established therapeutic methods and medical services to address potential complications.

关键词： Endoscopic submucosal dissection Complication Perforation Clinic

Advances in quantum dots for classical and non-classical light sources Invited Paper

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Chinese Optics Letters 2008年第10期6卷 718-723页

作者： Yasuhiko Arakawa satoshi Iwamoto satoshi Kako Masahiro Nomura Denis Guimard Research Center for Advanced Science and Technology Institute for Nano Quantum Information ElectronicsThe University of Tokyo4-6-1 Meguro-ku153-8505 TokyoJapan

Recent advances in quantum dots （QDs） for classical and non-classical light sources are presented. We have established metal organic chemical vapor deposition （MOCVD） technology for InAs-based QD lasers at 1.3 μm and achieved ultralow threshold in QD lasers with photonic crystal （PhC） nanocavity. In addition, single photon emitters at 1.55 μm, GaN-based single photon sources operating at 200 K, and high-Q PhC nanocavity have been demonstrated.

关键词： QDs Advances in quantum dots for classical and non-classical light sources Invited Paper AIN InAs

Application of 3D Scanned Big Data of Large-scale Cultural Heritage Objects Based on Noise-robust Transparent Visualization

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系统仿真学报 2023年第8期35卷 1635-1650页

作者： Tanaka satoshi College of Information Science and Engineering Ritsumeikan UniversityShiga 525-8577Japan

Three-dimensional(3D) scanning technology has undergone remarkable developments in recent *** acquired by 3D scanning have the form of 3D point *** 3D scanned point clouds have data sizes that can be considered big *** also contain measurement noise inherent in measurement *** properties of 3D scanned point clouds make many traditional CG/visualization techniques *** paper reviewed our recent achievements in developing varieties of high-quality visualizations suitable for the visual analysis of 3D scanned point *** demonstrated the effectiveness of the method by applying the visualizations to various cultural heritage *** main visualization targets used in this paper are the floats in the Gion Festival in Kyoto(the float parade is on the UNESCO Intangible Cultural Heritage List) and Borobudur Temple in Indonesia(a UNESCO World Heritage Site).

关键词： 3D scanning point cloud transparent visualization noise transparentization cultural heritage object

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Posture Maintenance Control of 2-Link Object By Nonprehensile Two-Cooperative-Arm Robot Without Compensating Friction

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IEEE/CAA Journal of Automatica Sinica 2019年第6期6卷 1397-1403页

作者： Changan Jiang satoshi Ueno Department of Mechanical Engineering Ritsumeikan University1-1-1 Noji-higashiKusatsuShiga 525-8577Japan

In this paper, a method to posture maintenance control of 2-link object by nonprehensile two-cooperative-arm robot without compensating friction is proposed. In details, a mathematical model of the 2-link object is firstly built. Based on the model, stable regions for holding motion of nonprehensile two-cooperative-arm robot are obtained while the 2-link object is kept stable on the robot arms with static friction. Among the obtained stable regions, the robust pairs of orientation angles of the 2-link object are found. Under the robust orientation angles, a feedback control system is designed to control the arms to maintain the 2-link object's posture while it is being held or lifted up. Finally, experimental results are shown to verify the effectiveness of the proposed method.

关键词： Nursing care nonprehensile robot posture maintenance static friction two-cooperative-arm robot

A pH-dependent molecular switch for virion uncoating

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Protein & Cell 2014年第9期5卷 653-654页

作者： satoshi Koike Neurovirology Project Tokyo Metropolitan Institute of Medical Science 2-1-6 Kamikitazawa Setagaya-ku Tokyo 156-8506Japan

Enterovirus 71, belonging to human enterovirus speCies A in the genus Enterovirus of the family Picornaviridae, is one of the main causative agents of hand-foot-mouth disease. It can also cause severe neurological diseases such as acute encephalitis, polio-like paralysis, and neurogenic pulmonary edema, and it has become a serious public health concern especially in the Asia-Pacific region.

关键词： Enterovirus Picornaviridae Asia-Pacific

Hepatic pseudolesions caused by alterations in intrahepatic hemodynamics

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World Journal of Gastroenterology 2021年第46期27卷 7894-7908页

作者： satoshi Kobayashi Department of Quantum Medical Technology Kanazawa University Graduate School of Medical SciencesKanazawa 9200942IshikawaJapan

Hepatic pseudolesion may occur in contrast-enhanced computed tomography and magnetic resonance imaging due to the unique haemodynamic characteristics of the *** concept of hepatic arterial buffer response(HABR)has become mainstream for the understanding of the mechanism of the reciprocal effect between hepatic arterial and portal venous *** HABR is thought to be significantly related to the occurrence of the abnormal imaging findings on arterial phase of contrast enhanced images,such as hepatic arterial-portal vein shunt and transient hepatic attenuation difference,which mimic hypervascular tumor and may cause clinical *** inflow to the liver also cause hepatic pseudolesion,and some of the cases may show histopathologic change such as focal hyperplasia,focal fatty liver,and focal sparing of fatty liver,and called *** understand these phenomena might be valuable for interpreting the liver imaging findings.

关键词： Pseudolesion Focal sparing of fatty liver Computed tomography Hepatic blood flow Hepatic hemodynamics Hyperplastic change

Surface roughness and its role in mediating cell adhesion on cobalt-chromium-molybdenum alloys

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Biosurface and Biotribology 2023年第4期9卷 161-168页

作者： satoshi Migita Graduate School of Science and Engineering Yamagata UniversityYonezawaJapan

Co-Cr-Mo ally(CCM)is commonly used for orthopaedic and dental implants due to its excellent mechanical properties and corrosion ***,the influence of surface roughness on cell attachment and proliferation remains *** study aimed to elucidate the impact of surface roughness of CCM on the attachment and proliferation of *** samples with different values of surface rouges were prepared by ***3T3-E1 mouse osteoblasts were used for cell culture *** attachment,morphology,and the expression of actin stress fibres,vinculin,and distri-bution of yes-associated protein were *** results suggest that surface rough-ness does not significantly affect cell attachment and proliferation on CCM,unlike on *** implies that other properties of CCM,such as physicochemical properties,may play a more substantial role in modulating cell *** study provides important insights into the design of CCM implants,suggesting that approaches beyond tuning surface roughness may be necessary to improve biocompatibility and osseointegration.

关键词： biointerface biological reaction biological response biomaterials biomedical application biosurface

Artificially frozen ground and related engineering technology in Japan

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Research in Cold and Arid Regions 2021年第2期13卷 77-86页

作者： satoshi Akagawa Cryosphere Engineering Laboratory TokyoJapan

Since the 1970's, frozen ground has been developing near the Tokyo Bay area around liquefied natural gas(LNG) inground storage tanks. For disaster prevention purposes, the tanks are constructed below the ground surface. Since the temperature of the liquid stored in the tanks is -162℃ the soil surrounding the tanks freezes. Since this frozen ground has existed for almost half a century, we have permafrost near Tokyo. The development of artificial frozen ground may cause frost heaving, resulting in frost heave forces that may cause structural damage of adjacent LNG in-ground storage ***, the demand for frozen ground engineering increased and consequently we now have advanced technology in this area. Fortunately, we use this engineering technology and artificial ground freezing for civil engineering, especially in big and crowded cities like Tokyo. This paper provides a summary of the testing apparatus, test methods, and assessment methods for frost heaving.

关键词： artificial ground freezing frost heave frozen ground engineering

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Genomics, Proteomics & Bioinformatics 2016年第2期14卷 103-112页

作者： Yusei Kobori satoshi Mizuta Graduate School of Science and Technology Hirosaki University

Graphical representation of DNA sequences is one of the most popular techniques for alignment-free sequence comparison. Here, we propose a new method for the feature extraction of DNA sequences represented by binary images, by estimating the similarity between DNA sequences using the frequency histograms of local bitmap patterns of images. Our method shows linear time complexity for the length of DNA sequences, which is practical even when long sequences, such as whole genome sequences, are compared. We tested five distance measures for the estimation of sequence similarities, and found that the histogram intersection and Manhattan distance are the most appropriate ones for phylogenetic analyses.

关键词： Genome sequence Mitochondria Bitmap image Occurrence frequency Distance measure