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p53突变型肝细胞癌的动态增强CT和钆塞酸二钠增强MRI影像特征

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国际医学放射学杂志 2023年第2期 235-235页

作者： K.Azusa M.Osamu Z.Yu O.Takahiro N.satoko S.Yasunori 朱伟杰

摘要基于分子分型的肝细胞癌（HCC）影像学特征对预测其恶性程度和预后具有重要意义。p53突变型HCC是一类主要的侵袭性亚型肝癌，但其影像学特征尚未明确。目的探

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Neuroendoine response in hypothalamus and pituitary of Da rats in experimental autoimmune encephalomyelitis

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Acta Pharmacologica Sinica 1999年第5期 96-96页

作者： Keiko BOUDA,satoko MATSUURA,Yuko TAKAOKA,Satoru NIWA,Takeyasu HOMMA,Hiroyuki TANAKA,Koichi SHUDO,Kenji KAWADA,Hiroichi NAGAI Department of Pharmacology Gifu Phannaceutical University Gifu Japan Department of Pharmacology Gifu Phannaceutical University Gifu Japan Department of Pharmacology Gifu Phannaceutical University Gifu Japan Department of Pharmacology Gifu Phannaceutical University Gifu Japan Department of Pharmacology Gifu Phannaceutical University Gifu Japan Department of Pharmacology Gifu Phannaceutical University Gifu Japan Faculty of Pharmaceutical Sciences Tokyo University Tokyo Japan Department of Pharmacology Gifu Phannaceutical University Gifu Japan Department of Pharmacology Gifu Phannaceutical University Gifu Japan

In the present experiment, we examined the changes of mRNA levels of cytokines,inducible nitric oxide synthase (iNOS), neurothophins and corticotropin release factor (CRF) and their receptors in hypothalamus and pituitary in experimental autoimmune encephalomyelitis(EAE)rats to analysis the endocrine response with immune during the development of the *** DA rats were immunized by injecting MBP and developed EAE disease with a peak of severity about 14 d later.

关键词： CRF

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冲绳之怒

作者： (澳)加文·麦考马克(Gavan McCormack) (日)乘松聪子(satoko Oka Norimatsu)

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建立国家开放大学在线辅导共同体探索

成人教育 2012年第12期32卷 4-9页

作者：保罗.川内张宇光中央广播电视大学外语学院北京100039

一个理想辅导技能的框架,与学生学习的成果相关。这些学生需要掌握各类知识和技能,这些知识技能包括认知领域以及其他四个领域。辅导工作(行为)帮助学生掌握各种技能(如判断内涵的技能、批判性思考的技能等等),而许多教师本身可能就缺... 详细信息

一个理想辅导技能的框架,与学生学习的成果相关。这些学生需要掌握各类知识和技能,这些知识技能包括认知领域以及其他四个领域。辅导工作(行为)帮助学生掌握各种技能(如判断内涵的技能、批判性思考的技能等等),而许多教师本身可能就缺乏这些技能。这种学习和学习技能涵盖了所有这五个学习领域:环境、认知、元认知、情感和管理领域。辅导教师在学生作业中通过批改评阅的方式留下的辅导反馈,可以而且应该尽可能合理地涵盖所有五个领域。文章回顾了开放式学习中在线辅导的环境、认知、元认知、情感与管理五种领域的功能,来探索通过建立辅导教师在线共同体的积极作用。

关键词：开放大学在线辅导理论框架与方法

日本关于东北亚研究成果选编——关于满学研究论文目录选(三)(1895—1968)

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满语研究 2001年第1期 108-114页

作者：河内良弘赵阿平杨惠滨黑龙江省满语研究所黑龙江哈尔滨150080

关键词：日本东北亚研究满学研究论文目录

The Association of Autism Spectrum Disorders and Symptoms of Asthma, Allergic Rhinoconjunctivitis and Eczema among Japanese Children Aged 3 - 6 Years

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Health 2017年第8期9卷 1235-1250页

作者： Daisuke Hori Hiromasa Tsujiguchi Yasuhiro Kambayashi Toshio Hamagishi Masami Kitaoka Junko Mitoma Hiroki Asakura Fumihiko Suzuki Enoch Olando Anyenda Nguyen Thi Thu Thao Yohei Yamada satoko Tamai Koichiro Hayashi Yuri Hibino Aki Shibata Takiko Sagara Shinichiro Sasahara Ichiyo Matsuzaki Hiroyuki Nakamura Department of Environmental and Preventive Medicine Graduate School of Medical Science Kanazawa University Kanazawa Japan Faculty of Medicine University of Tsukuba Tsukuba Japan International Institute for Integrative Sleep Medicine University of Tsukuba Tsukuba Japan

There is insufficient epidemiological evidence on the relationship between autism spectrum disorder (ASD) and allergic diseases. We performed a cross-sectional survey to elucidate the associations between them using validated screening tools. The participants were children aged 3 - 6 years attending kindergarten or nursery school in Shika Town, Japan (n = 417;valid response rate = 80.4%). Autism spectrum features were scored on the Social Communication Questionnaire (SCQ). Allergic symptoms (asthma, allergic rhinoconjunctivitis, and eczema) were determined according to the criteria of the International Study of Asthma and Allergies in Childhood. A total of 15 children (4.5%) had an SCQ score of 11 points or higher. The prevalence of symptoms was 14.7% for asthma, and 5.3% for allergic rhinoconjunctivitis, and 11.4% for eczema. Logistic regression indicated that symptoms of eczema were significantly associated with SCQ scores of 11 points or higher [odds ratio (OR), 4.38;95% confidence interval (CI), 1.41 - 13.59]. The association persisted after adjustment for age, sex, and BMI (OR, 3.84;95% CI, 1.20 - 12.24). Moreover, asthmatic symptoms were significantly associated with male sex (OR, 2.09;95% CI, 1.12 - 3.92) and overweight status (OR, 2.45;95% CI, 1.03 - 5.83). This suggests that higher SCQ scores, which imply more autism spectrum features, are associated with higher prevalence of eczema symptoms. While no causal relationships can be made, ASD might be associated with eczema.

关键词： Asthma Autism Spectrum Disorder Eczema Early Screening Social Communication Questionnaire

Effect of Introduction of Irrigation on Technical Efficiency of Olive-Growing Farms in Tunisia

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Journal of Agricultural Science and Technology(A) 2013年第9期3卷 667-676页

作者： Kenichi Kashiwagi Mohamed Kefi Mohamed Ksibi Monem Kallel Atsushi kawachi Hiroko Isoda Faculty of Humanities and Social Sciences University of Tsukuba Japan The Alliance for Research on North Africa (ARENA) University of Tsukuba Japan Water Researches and Technologies Center of Borj-Cedria (CERTE) Tunisia National Engineering School of Sfax (ENIS) University of Sfax Tunisia Faculty of Life and Environmental Sciences University of Tsukuba Japan

This paper investigates the effect of the introduction of an irrigation technique on the technical efficiency of olive production in a sample of olive-growing farms in Tunisia, estimating the Cobb-Douglas form of stochastic frontier production function. Results indicate that estimated technical efficiency scores vary, ranging from a minimum of 3.0% to a maximum of 91.2% with a mean value of 61.2%. This suggests that olive-growing farms in Tunisia can increase their production on average by 38.8% through more efficient use of technology and inputs. The introduction of irrigation increased productivity, however, the estimated technical efficiency of irrigated olive farms varies across farms and they are less efficient than non-irrigated farms. This finding suggests that the introduction of irrigation to non-irrigated farms has the potential to increase production levels, however, the current production of the irrigated farms is far from the "best practice frontier" that realizes maximum possible output. Accumulation of experience and knowledge by farm owners and selection of olive cultivar significantly contribute to improving technical efficiency.

关键词：灌溉技术技术效率农场主突尼斯橄榄种植生产函数平均值

童年的社会心理不良影响和成人社会经济地位低可预测心血管病

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中华高血压杂志 2015年第7期23卷 611-611页

作者：刘莉叶鹏 Halonen JI Stenholm S Pentti J kawachi I Subramanian SV Kivimaki M Vahtera J

已知童年的社会不良心理因素（如父母离异,长期的财政困难）和成人社会经济地位低都与心血管病（cardiovascular disease,CVD）风险增加相关,但它们对疾病风险的协同作用尚不清楚。方法与结果：纳入芬兰公共部门研究中37 699名成人受试... 详细信息

已知童年的社会不良心理因素（如父母离异,长期的财政困难）和成人社会经济地位低都与心血管病（cardiovascular disease,CVD）风险增加相关,但它们对疾病风险的协同作用尚不清楚。方法与结果：纳入芬兰公共部门研究中37 699名成人受试者（受试者资料通过2000-2008年居住地址与全国社会经济情况资料网相连接,

关键词：社会经济地位心血管病成人不良影响社会心理童年预测不良心理因素

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野生大豆、黑豆和大豆的异黄酮类成分比较

大豆科学 2008年第2期27卷 315-319页

作者：周三关崎春雄岳旺泽聪子杨志宏青岛大学医学院药学系山东青岛266021 北海道医疗大学药学部日本北海道061-0293

野生大豆主产于中国,古时为珍贵药材,但现代将其作药用的研究较少。以同样种植条件下收获的野生大豆、黑豆和大豆为材料,用HPLC法、凯氏定氮法和索氏残渣法分别测定其大豆异黄酮、蛋白质和脂肪含量,以此比较野生大豆、黑豆和大豆的药用... 详细信息

野生大豆主产于中国,古时为珍贵药材,但现代将其作药用的研究较少。以同样种植条件下收获的野生大豆、黑豆和大豆为材料,用HPLC法、凯氏定氮法和索氏残渣法分别测定其大豆异黄酮、蛋白质和脂肪含量,以此比较野生大豆、黑豆和大豆的药用价值。结果表明:12种大豆异黄酮类组分的总含量大小顺序为:野生大豆>黑豆>大豆;野生大豆和黑豆中黄豆苷和染料木苷含量特别突出,而且其相应的苷元含量也较高,大豆中则是丙二酰基化的黄豆苷和丙二酰基化的染料木苷含量特别突出,而其相应的苷元组分含量极低;相关性分析表明三种大豆的不同品种,大豆异黄酮总含量与其百粒重和脂肪含量呈极显著负相关,但与蛋白质含量的相关性不显著。结果说明野生大豆的药用研究应受到重视。

关键词：野生大豆黑豆大豆大豆异黄酮