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影响美国银屑病患者健康和费用支出的医疗相关因素

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世界核心医学期刊文摘（皮肤病学分册） 2005年第6期1卷 4-4页

作者： kulkarni A.S. Balkrishnan R. Richmond D. 张宪旗

The impact of psoriasis medication therapy on costs and patient outcomes in large nationally representative samples needs further examination. This study examined the association between factors related to medication use, health status, and health care costs associated with psoriasis in the United States. A cross-sectional cohort study was performed using the 2000 Medical Expenditure Panel Survey database. Information on health care service use, health status (EuroQol-5D instrument), and patient demographics were obtained from the database representing approximately 1.1 million patients with psoriasis. EuroQol was used in the Medical Expenditure Panel Survey. Weighted multiple linear regression analysis indicated that use of topical corticosteroid therapy was associated with a decrease in psoriasis-specific health care costs (53.2% lower than average costs vs patients using no medications, P=. 022) and better health status (34.0% higher than average scores vs patients using no medications, P=. 006). We observed an association with topical corticosteroids for treatment of psoriasis on health care outcomes and costs.

关键词：银屑病医疗花费调查委员会局部应用横断面调查人口统计

理解冠心病死亡率与心血管疾病总死亡率之间的矛盾现象:一种增强美国心血管疾病死亡统计学可比性的方法

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世界核心医学期刊文摘（心脏病学分册） 2006年第7期2卷 39-39页

作者： Murray C.J.L. kulkarni S.C. Ezzati M. 刘少伟 Harvard School of Public Health 665 Huntington Ave Boston MA 02115 United States Dr.

Background -Coronary heart disease(CHD) represents the largest share of cardiovascular disease in the United States, but there are conspicuous discrepancies between CHD and total cardiovascular death rates across the states, possibly due in part to variations in physician assignment of causes of death. Our aim was to identify exogenous individual-and community-level predictors of cause-of-death assignment and variability and to use these predictors to improve the comparability of CHD mortality estimates across states. Methods and Results -We performed a multinomial logistic regression analysis to estimate the effect of individual-and community-level factors on the likelihood of a death being certified as 1 of 3 ill-defined clusters(general atherosclerosis and unspecified heart disease, heart failure, and cardiac arrest) relative to being certified as CHD. The individual-level variables were the decedent’s race, sex, age, education, and place of death; the community-level variable was the number of cardiologists per capita. We used the model to estimate state-level CHD rates that are standardized with regard to the levels of individual-and community-level determinants of cause-of-death assignment. Decedents who died in hospitals and in counties with more cardiologists per capita were more likely to be assigned to CHD than to the ill-defined categories, as were white males relative to other race-sex combinations. Adjustment for these factors resulted in substantially improved correlation between death rates for CHD and all cardiovascular causes. Increases in CHD death rates across states after adjustment for external predictors of cause-of-death assignment ranged from 2%(North Dakota) to 72%(Washington,DC); NewYork had a decrease(1%) in CHD death rates after adjustment. Nationally, CHD death rates increased 10%for males and 15%for females. The total number of deaths in 2001 attributed to CHD in patients over 30 years of age rose from 433 625 to 489 836 after adjustmen

关键词：冠心病死亡心血管疾病总死亡率可比性矛盾现象粥样硬化医生数死亡原因心脏停搏全身动脉

经血压校正的动脉僵硬度指标的预测价值:脉搏波传导速度、心踝血管指数与血压校正的心踝血管指数的比较

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中华高血压杂志 2023年第3期31卷 300-300页

作者： Spronck B Obeid MJ Paravathaneni M Gadela NV Singh G Magro CA kulkarni V Kondaveety S Gade KC Bhuva R Kulick-Soper CM Sanchez N Akers S Chirinos JA 刘青郑武洪不详

Am J Hypertens,2022,35(3):272-280.脉搏波传导速度(pulse wave velocity,PWV)测值受血压影响,促进了血压校正指标心踝血管指数(cardio-ankle vascular index,CAVI)和CAVI0(通过理论/数学模型对CAVI进行额外的血压校正得到)的发展。本... 详细信息

关键词：脉搏波传导速度心踝血管指数动脉僵硬度血压影响预测价值风险预测 CAVI PWV

低辐射剂量多层CT自适应统计迭代重建技术(ASIR)诊断尿路结石的研究:辐射剂量可以降低至多少?

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国际医学放射学杂志 2012年第6期 589-589页

作者： N.M.kulkarni R.N.Uppot B.H.Eisner D.V.Sahani 史佳培 Departments of Abdominal Imaging and Intervention Massachusetts General Hospital55 fruit Stwhite 270bostonMA02114

摘要目的探讨CT扫描条件(80kV、100kV;管电流:75～150mA)、自适应迭代重建技术(ASIR)对尿路结石病人的影像质量的影响。材料与方法本研究符合HIPAA规定并获得伦理审查委员会批准,前瞻性低剂量CT扫描获得了病人知情同意,

关键词：尿路结石影像质量辐射剂量 ASIR CT

与FBLN4基因新突变相关的独特致命性遗传性动脉综合征的影像表现

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国际医学放射学杂志 2014年第5期 500-500页

作者： R.Rajeshkannan C.kulkarni M.Kappanayil S.Nampoothiri F.Malfait A.De Paepe 罗松 Department of Radiology Amrita Institute of Medical SciencesAIMS(PO)ErnakulamIndia 682041

摘要目的展示了一种新鉴定的疾病———致命性动脉病的影像表现,该疾病发生在印度南部特定的区域,与编码fibulin-4 蛋白的基因新突变有关。方法总共 31 例患儿被纳

关键词：影像表现动脉 FBLN4 血管成像新突变分支基因

与单能CT血管成像比较,单源双能CT腹部血管成像的初步经验:影像质量、增强效果、诊断及辐射剂量

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国际医学放射学杂志 2013年第2期 194-194页

作者： D.F. Pinho N.M. kulkarni A. Krishnaraj S.P. Kalva D.V. Sahani 赵芳 Division of Abdominal Imaging and Intervention Mas- sachusetts General Hospital 55 Fruit StreetWhite270BostonMA 02114 USA

目的与单能CT(SE-CT)比较,评价虚拟单能谱成像(VMS)的影像质量及对腹主动脉疾病密度成像的可行性。方法回顾性研究35例病人(男32例,平均年龄76.5岁)主髂动脉系统的单源双能CT(ssDECT)与SE-CT的对比。对ssDECT数据进行后处理以产生不同能... 详细信息

目的与单能CT(SE-CT)比较,评价虚拟单能谱成像(VMS)的影像质量及对腹主动脉疾病密度成像的可行性。方法回顾性研究35例病人(男32例,平均年龄76.5岁)主髂动脉系统的单源双能CT(ssDECT)与SE-CT的对比。对ssDECT数据进行后处理以产生不同能谱VMS及水密度(WD)影像。采用5分制评估影像质量参数。记录主髂动脉密度衰减及对比噪声比(CNR)。对比WD与真正的非强化(TNE)影像。记录辐射剂量并进行统计学分析。结果 70keV时的影像质量更高(P<0.01),50keV时的肾动脉分支显示更清楚(P<0.005)。50、70keV时的密度衰减和CNR均较高(P<0.0001)。WD成像具有可诊断的影像质量,但噪声比TNE影像高(P<0.0001)。单期ssDECT的辐射剂量比双期SE-CT低(P<0.0001)。结论与SE-CT的120kV影像相比,ssDECT的70keV影像具有更高的对比增强效果,并能改善主髂动脉CT影像质量。WD影像在潜在降低剂量方面可以作为TNE影像的有效代替。要点①多层CT血管成像目前是一种常规检查。②ssDECT可同时产生不同的管电压。③70keV时影像比传统SE-CT影像质量更高。④70keV时影像比SE-CT影像噪声更少。

关键词：双能CT CT血管成像多层CT 辐射剂量虚拟平扫图像

腋窝淋巴结疑为乳腺癌转移:超声引导下14G芯针穿刺活检采样100例的临床经验

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国际医学放射学杂志 2009年第2期32卷 175-175页

作者： H.Abe R.A.Schmidt K.kulkarni C.A.Sennett J.S.Mueller G.M.Newstead 朱玉兆 Department of Radiology University of Chicago

目的研究超声引导下腋窝淋巴结芯针活检的临床应用，以及可预测淋巴结转移的异常超声征象。方法该回顾性研究符合HIPAA法案，获审查委员会批准，无需病人知情同意。144例经过腋窝淋巴结超声评估的原发性乳腺癌病人中的100例接受了... 详细信息

目的研究超声引导下腋窝淋巴结芯针活检的临床应用，以及可预测淋巴结转移的异常超声征象。方法该回顾性研究符合HIPAA法案，获审查委员会批准，无需病人知情同意。144例经过腋窝淋巴结超声评估的原发性乳腺癌病人中的100例接受了超声引导下腋窝淋巴结的14G芯针活组织检查。活检针是可控的，而不是传统使用的投掷型（throw-type）针。

关键词：腋窝淋巴结乳腺癌转移超声引导穿刺活检临床经验采样淋巴结转移活组织检查

Heat-tolerant maize for rainfed hot, dry environments in the lowland tropics: From breeding to improved seed delivery

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Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

The Crop Journal 2023年第4期

作者： Pervez H.Zaidi Madhumal Thayil Vinayan Sudha K.Nair Prakash H.Kuchanur Ramesh Kumar Shyam Bir Singh Mahendra Prasad Tripathi Ayyanagouda Patil Salahuddin Ahmed Aamir Hussain Atul Prabhakar kulkarni Passang Wangmo Mitchell R.Tuinstra Boddupalli M.Prasanna

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this *** There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid