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Occurrence data may provide unreliable thermal preferences and breadth of species

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Current Zoology 2015年第6期61卷 972-982页

作者： sara VILLEN-perez Luis M. CARRASCAL Department of Biogeography and Global Change National Museum of Natural Sciences MNCN-CSIC. C/José Gutiérrez Abascal 2 28006 Madrid Spain.

Accurate information on the thermal preference and specialization of species is needed to understand and predict spe- cies geographical range size and vulnerability to climate change. Here we estimate the position and breadth of species within thermal gradients based on the shape of the response curve of species abundance to temperature. The objective of the study is to compare the measurements of this approach based on abundance data with those of the classical approach using species＇ occur- rence data. The relationship between species＇ relative abundance and minimum winter temperature of 106 bird species wintering in the Iberian Peninsula is modeled at 100 Km2 resolution with quadratic logistic regressions. From these models we calculated the preferred temperature of species as the temperature at which the abundance is maximized, and the thermal breadth of species as the relative area under the temperature-abundance curve. We also estimated the thermal preferences and breadth of species as the average temperature and temperature range of the UTM cells in which the species are present. The abundance-temperature response curves reveal that birds prefer higher temperatures to overwinter, and are more thermally selective, than is measured by the classical approach. Moreover, response curves detect a higher inter-specific variability in both thermal preferences and ther- mal breadth of species. As occurrence data gives the same weight to cells with one or many individuals, the average temperature of the cells in which the species is present roughly reflects the average temperature in the region of study and not the environ- mental preferences of species .

关键词： Abundance-temperature response curve Birds Species occurrence Thermal breadth Thermal preferences Winter

Misfolded amyloid-βstrains and their potential roles in the clinical and pathological variability of Alzheimer’s disease

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Neural Regeneration Research 2023年第1期18卷 119-120页

作者： sara Kelley Nelson perez-Urrutia Rodrigo Morales Department of Neurology University of Texas Health Science Center at HoustonHoustonTXUSA Centro Integrativo de Biologia y Quimica Aplicada(CIBQA) Universidad Bernardo O’HigginsSantiagoChile

Potential causes for the clinical and pathological variability observed in Alzheimer’s disease(AD):AD is an age-related neurodegenerative disorder characterized by the impairment of cognitive functions such as memory,learning,and *** commonly described clinical symptoms are due to particular pathological changes in the brain,including inflammation,synaptic loss,and neuronal *** changes are a consequence of the accumulation of abnormally folded amyloid-β(Aβ)and tau proteins in specific areas of the central nervous *** the progressive aging of the world’s population,the number of people affected by AD is expected to substantially and consistently increase in the coming *** positions AD as one of the main public health challenges in the near future.

关键词： clinical Alzheimer amyloid

Woodland Mediterranean birds can resist a dry extreme cold wave

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Current Zoology 2014年第4期60卷 429-437页

作者： sara VILLEN-perez Luis M. CARRASCAL Department of Biogeography and Global Change Museo Nacional de Ciencias Naturales (CSIC) C/Jos6 Guti6rrez Abascal 228006 Madrid Spain

The ecological consequences of climate extreme events are still poorly understood, especially those related to cold episodes. Winter cold spells might imperil the energy balance of small passerines, thus compromising their survivorship. Here we analyze how the abundance and habitat use of three tree-gleaning passerine species wintering in a montane oakwood of central Spain at ca. 1,300 m a.s.1, was influenced by the cold wave that hit Europe in February 2012. We monitored temperature, wind and the relative abundance of great tit Parus major, blue tit Cyanistes caeruleus and long-tailed tit Aegithalos caudatus in 15 plots throughout three periods： before, during and after the cold wave. Our results clearly rule out widespread mortality and temporal migration of the studied passerine populations, as the abundance of these species did not diminish during the cold wave. Moreover, the species usually foraging higher in the tree canopy -and thus more exposed to windmoved to the less windy woodland plots （long-tailed tit） and reduced their foraging height above ground during the cold wave （long-tailed tit and blue tit）, probably to mitigate the deleterious effects of wind chill. Therefore, these forest birds were able to cope with a dry cold wave that was statistically extreme in terms of temperature and wind chill, according to the historic climate records of the region. It seems that, at least when foraging substrates are not heavily covered by snow or ice, Mediterranean birds can resist an extreme cold wave [Current Zoology 60 （4）： 429-437, 2014].

关键词： Cold wave Harsh weather Mediterranean oakwoods Temperature Tree-gleaning birds Wind chill

Bacterial extracts and bioformulates as a promising control of fruit body rot and root rot in avocado cv. Hass

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Journal of Integrative Agriculture 2020年第3期19卷 748-758页

作者： David GRANADA Lorena LÓPEZ-LUJAN sara RAMIREZ-RESTREPO Juan MORALES Carlos PELÁEZ-JARAMILLO Galdino ANDRADE Juan Carlos BEDOYA-perez Phytosanitary and Biological Control Unit Corporation for Biological ResearchMedellin 050034Colombia Faculty of Health Sciences Institution University Colegio Mayor de AntioquiaMedellin 050034Colombia Department of Agronomic Sciences National University of ColombiaMedellin 050034Colombia Faculty of Exact Sciences University of AntioquiaMedellin 050010Colombia Department of Microbiology Londrina State UniversityLondrina 86051-990Brazil

At least 20-40% of annual losses of avocado crops are caused by pathogenic *** chemical treatments of these diseases are inefficient,cause environmental pollution and are increasingly restricted by international *** work aimed to assess the biocontrol capacity of a bacterial extract to protect avocado fruits and plants from pathogen *** from the bacterial isolate Serratia ***5.1 were obtained from liquid fermentations in a biorreactor.A body rot postharvest infection model with Colletotrichum gloeosporioides on fruits was ***,packaging conditions were simulated using the bacterial extract and the commercial fungicide prochloraz as a positive ***,seedlings infections with Phytophthora cinnamomi were performed on two types of avocado(West Indian race and ***).The Area Under Disease Progress Curve(AUDPC) was recorded using the bacterial extract and a commercial product with fosetyl-aluminium as *** bacterial extract significantly reduced infections by *** on injured avocado fruits at 31.1 μg mL^-*** fruits were also protected against body rot infections at the same concentration and showed no significant differences with the commercial *** the other hand,AUDPC in the seedlings was significantly reduced with the extract treatment at 3 μg mL^-1 compared to the ***,a possible phytotoxicity effect of the extract was evidenced in the seedlings and confirmed by pathogen recovery and tests on Raphanus sativus ***,formulations of the extracts(emulsion and emulsifiable concentrate) were prepared,and bioactive stability was assessed for 8 *** emulsion formulates demonstrated very stable bioactivity against *** extract and the emulsion formulate showed promising results for the control of avocado *** bioproducts based on this type of active principles could be developed for the benefit of avocado industry.

关键词： Colletotrichum gloeosporioides Phytophthora cinnamomi Serratia sp. antagonistic microbes secondary metabolites biofungicide

The Security of Platelet-rich Plasma in Sports-relatedInjuries

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Journal of Health Science 2014年第8期2卷 363-369页

作者： Leticia Rivero Gonzalez Gabriel Lupon Escobar LluisTil perez sara Estevez Sarmiento Fuerteventura Hospital Clinica Roca Sports Medical Unit Gran Canaria Hospital Universitario Insular de Gran Canaria LasPalmas de Gran Canaria Las Palmas 35016 Spain Sports Medicine Consorci Sanitari de Terrassa (CST) in Olympic Training Center (CAR) Sant Cugat del Vall~s 08173 Spain Sports Medicine FC Barcelona Barcelona 08028 Spain Hospital Universitario Insular de Gran Canaria Las Palmas de Gran Canaria Las Palmas 35016 Spain

Platelet-rich plasma （PRP） therapy in orthopedics and sports medicine has seen an expansion in use since 2003. Theobjective of this study is to not only review evidence of clinical effectiveness but also to evaluate its security and detect any disparitybetween its use and its popularity. A prospective, descriptive study, which included 104 athletes were performed. Minor adverse effectswere recorded and these were self-limited. Although there is a lack of more detailed studies which compare other factors, PRP therapyhas been shown to have positive results in relation to certain lesions.

关键词： Sports medicine, growth factors, muscles, tendons, ligaments, platelet-rich plasma.

Spatial distribution and network morphology of epicardial,endocardial,interstitial,and Purkinje cell-associated elastin fibers in porcine left ventricle

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Bioactive Materials 2023年第1期19卷 348-359页

作者： Xiaodan Shi Song Zhang Yue Liu Bryn Brazile Jim Cooley J.Ryan Butler sara R.McMahan Karla L.perez Jiazhu Xu Timothy Eastep Kytai T.Nguyen Pietro Bajona Matthias Peltz Huajian Gao Yi Hong Jun Liao Department of Bioengineering University of Texas at ArlingtonArlingtonTX76010USA College of Engineering and College of Veterinary Medicine Mississippi State UniversityMississippi StateMS39762USA School of Engineering Brown UniversityProvidenceRI02912USA College of Engineering Nanyang Technical University308232Singapore Department of Cardiovascular and Thoracic Surgery University of Texas Southwestern Medical CenterDallasTX75390USA Allegheny Health Network-Drexel University College of Medicine PittsburghPA15212USA

Cardiac extracellular matrices(ECM)play crucial functional roles in cardiac *** studies have mainly focused on collagen,the major structural ECM in heart *** role of elastin in cardiac mechanics,however,is poorly *** this study,we investigated the spatial distribution and microstructural morphologies of cardiac elastin in porcine left *** demonstrated that the epicardial elastin network had location-and depth-dependency,and the overall epicardial elastin fiber mapping showed certain correlation with the helical heart muscle fiber *** compared to the epicardial layer,the endocardial layer was thicker and has a higher elastin-collagen ratio and a denser elastin fiber network;moreover,the endocardial elastin fibers were finer and more wavy than the epicardial elastin fibers,all suggesting various interface *** myocardial interstitial elastin fibers co-exist with the perimysial collagen to bind the cardiomyocyte bundles;some of the interstitial elastin fibers showed a locally aligned,hinge-like structure to connect the adjacent cardiomyocyte *** collagen-elastin combination reflects an optimal design in which the collagen provides mechanical strength and elastin fibers facilitate recoiling during ***,cardiac elastin fibers,along with collagen network,closely associated with the Purkinje cells,indicating that this ECM association could be essential in organizing cardiac Purkinje cells into“fibrous”and“branching”morphologies and serving as a protective feature when Purkinje fibers experience large deformations in *** short,our observations provide a structural basis for future in-depth biomechanical investigations and biomimicking of this long-overlooked cardiac ECM component.

关键词： Heart ECM Epicardial elastin Endocardial elastin Interstitial elastin Purkinje-cell associated elastin

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鸭疫里默氏杆菌感染的全球重要性

国外畜牧学（猪与禽） 2017年第10期37卷 21-22页

作者：唐彩琰 sara perez

Riemer于1904年首次报告了在家禽上发生的一种流行性败血症。鸭疫里默氏杆菌感染被认为是一种新的鸭病——鸭败血病或传染性浆膜炎,是生长期鸭的一种常见败血性疾病,在全球都具有重要影响力。

关键词：鸭疫里默氏杆菌感染鸭疫巴氏杆菌表型特征黄杆菌属莫拉氏菌发病率杆菌病

Plasmonic metal-organic frameworks for surface-enhanced Raman scattering

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Plasmonic metal-organic frameworks for surface-enhanced Rama...

Motor Effects of 1,3-Disubstituted 8-Styrylxanthines as A_(1) and A_(2) Adenosine-Receptor Antagonists in Rats

第二十届全国光散射学术会议（CNCLS20）

作者：郑广超 Jorge perez-Juste 洪梅 sara Bals Luis M.Liz-marzan 郑州大学物理工程学院 CINBIO Campus Universitario Lagoas-Marcosende 化学生物学与生物技术学院北京大学深圳研究生院 EMAT-University of Antwerp CIC biomaGUNE Bionanoplasmonics Laboratory

金属-有机骨架化合物（metal–organic frameworks,MOFs）由于其比表面积大、孔径均一等优点,在催化、光学、电学等领域引起了广泛的关注。最近,基于MOFs的形貌控制研究其性能的形貌依赖性是一个热点。众所周知,表面活性剂能够很好的控... 详细信息

金属-有机骨架化合物（metal–organic frameworks,MOFs）由于其比表面积大、孔径均一等优点,在催化、光学、电学等领域引起了广泛的关注。最近,基于MOFs的形貌控制研究其性能的形貌依赖性是一个热点。众所周知,表面活性剂能够很好的控制晶体纳米颗粒的形貌。在这里,我们设计了一种利用双表面活性剂,十六烷基三甲基溴化铵（cetyltrimethylammonium bromide,CTAB）和三羟甲基氨基甲烷（tris（hydroxymethyl）aminomethane,TRIS）,来有效的控制MOFs的形貌[1]。另外,单一的金属纳米颗粒包覆在MOFs当中形成的核-壳结构能够有效的提高该等离激元MOFs在催化过程中的稳定性和选择性。我们发展了一种不依赖与金属纳米颗粒形貌、组分、尺寸的等离激元MOFs的制备方法。同时,由于等离激元纳米颗粒的局域表面等离子体共振效应,等离激元MOFs还可以通过利用表面增强拉曼散射（surface-enhanced Raman scattering,SERS）研究了MOFs孔径的灵活性[2]。

关键词：等离激元MOFs 孔径灵活性表面增强拉曼散射

来源： cnki会议评论

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Pharmacology & Pharmacy 2013年第3期4卷 303-311页

作者： Ilhuicamina Daniel Limon-perez de Leon Maria del Carmen Parra-Cid Alejandro Munoz-Zurita Saul Alejandro Merino-Contreras sara Montiel-Smith Socorro Meza-Reyes Gerardo Ramirez-Meja Jesus Sandoval-Ramirez Facultad de Ciencias Quimicas Benemerita Universidad Autonoma de PueblaPueblaMexico Instituto Nacional de Rehabili-tacion Unidad de Ingenieria de TejidosTerapia Celular y Medicina RegenerativaMexico DFMexico.

A series of 1,3-substituted 8-styrylxanthines (11a-d) was synthesized, under chemo- and regioselective conditions, in a good overall yield. The compounds showed affinity towards both A1 and A2A-adenosine receptors by radioligand binding by means of in vitro assays. The (E)-3-ethyl-1-propyl-8-styrylxanthine (11a) showed the greatest affinity towards the A2A receptor, whereas (E)-3-pentyl-1-propyl-8-styrylxanthine (11d) showed the greatest affinity for the A1 receptor. When the 8-styrylxanthines 11a (A15Et) and 11c (A15Bu) were administrated in rats, which were previously injured with 6-hydroxydopamine at the substantia nigra pars compacta (SNc), the turning behavior decreased 50%. Based on these results we propose to A15Et as a potential compound to treat some symptoms of Parkinson’s disease.

关键词： Xantines Adenosine Receptors Antagonists Turning Behavior Anti-Parkinsonian Drugs