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Burn recidivism:a 10-year retrospective study characterizing patients with repeated burn injuries at a large tertiary referral burn center in the United States

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Burns & Trauma 2019年第1期7卷 75-84页

作者： Sarah L.Laughon Bradley n.Gaynes Lori P.Chrisco samuel W.Jones Felicia n.Williams Bruce A.Cairns Gary J.Gala Department of Psychiatry 101 Manning DriveCB#7160Chapel HillNC 27599-7160USA Department of Surgery 4001 Burnett-Womack BuildingCB#7050Chapel HillNC 27599-7050USA north Carolina Jaycee Burn Center 101 Manning DriveCB#7206Chapel HillNC 27599-7600USA

Background:Psychiatric and substance use disorders are common among trauma and burn patients and are known risk factors for repeat episodes of trauma,known as trauma *** epidemiology of burn recidivism,specifically,has not been *** study aimed to characterize cases of burn recidivism at a large US tertiary care burn center and compare burn recidivists(RCs)with non-recidivists(nRCs).Methods:A 10-year retrospective descriptive cohort study of adult burn patients admitted to the north Carolina Jaycee Burn Center was conducted using data from an electronic burn registry and the medical *** variables were reported using medians and interquartile ranges(IQR).Chi-square and Wilcoxon-Mann-Whitney tests were used to compare demographic,burn,and hospitalization characteristics between nRCs and ***:A total of 7134 burn patients were admitted,among which 51(0.7%)were RCs and accounted for 129(1.8%)*** the 51 RCs,37 had two burn injuries each,totaling 74 admissions as a group,while the remaining 14 RCs had between three and eight burn injuries each,totaling 55 admissions as a *** to nRCs,RCs were younger(median age 36 years vs.42 years,p=0.02)and more likely to be white(75%vs.60%,p=0.03),uninsured(45%vs.30%,p=0.02),have chemical burns(16%vs.5%,pnd have burns that were≤10%total body surface area(89%vs.76%,p=0.001).The mortality rate for RCs *** did not differ(0%vs.1.2%,p=0.41).Psychiatric and substance use disorders were approximately five times greater among RCs compared to nRCs(75%vs.15%,pn total hospital charges per patient were nearly three times higher for RCs ***($85,736 vs.$32,023,pnclusions:Distinct from trauma recidivism,burn recidivism is not associated with more severe injury or increased *** to trauma recidivists,but to a greater extent,burn RCs have high rates of comorbid psychiatric and medical conditions that contribute to increased health care u

关键词： Burn recidivism Consult psychiatry Substance use disorder Repeat burn injury

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Record of Early Tonian mafic magmatism in the central Espinhaco(Brazil):new insights for break-up of the neoproterozoic landmass ancestor of Sao Francisco-Congo paleocontinent

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Geoscience Frontiers 2020年第6期11卷 2323-2337页

作者： Helen F.Moreira AndréDanderfer Alice F.O.Costa samuel M.Bersan Cristiano C.Lana Gláucia n.Queiroga Post Graduate Program of Department of Geology Mine SchoolFederal University of Ouro PretoBrazil Department of Geology Mine SchoolFederal University of Ouro PretoBrazil

Petrological characterization,U-Pb geochronology,Lu-Hf analyses and major and trace element data from mafic intrusions in the Central Espinhaco(central portion of the Brazilian shield)are used here to investigate the geological significance of the Early neoproterozoic magmatism in the context of the Sao Francisco-Congo *** mafic bodies are represented by medium to coarse-grained metagabbros with plagioclase,amphibole and *** U-Pb isotopic data from two samples yielded weighted mean 206pb/238U ages of 895±3.4 Ma(MSWD=1.7)and 896±2.4 Ma(MSWD=0.64),regarded as the best estimates for the crystallization age of these mafic *** and trace element data(including REEs)show that the gabbros originated from a subalkaline tholeiitic magma,typical of intraplate *** rocks are slightly enriched in LREEs and LILEs and depleted in *** new isotope and geochemical data,along with regional knowledge,indicate that these metagabbros mark the beginning of an important Tonian-age extensional tectonic event of the landmass of which the Sao Francisco-Congo paleocontinent was part(Rodinia supercontinent or Central African block?).We furthermore suggest that these rocks belong to a prominent suite of Tonian-age mafic rocks that mark a diachronic breakup attempt of this landmass which may have occurred from south to north along the Espinhaco mountain range.

关键词： Mafic rocks Espinhaco basin Sao Francisco-Congo paleocontinent Tonian rifting U–Pb geochronology

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ADAM17/TACE:a key molecule in brain injury regeneration

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neural Regeneration Research 2019年第8期14卷 1378-1379页

作者： samuel Dominguez-Garcia Carmen Castro noelia Geribaldi-Doldan Area de Fisiologia Facultad de Medicina Universidad de Cadiz Cadiz Spain Instituto de Investigacion e Innovacion Biomedica de Cadiz (InIBICA) Universidad de Cadiz Cadiz Spain

It has been many years since "the tumor necrosis factor-a-converting enzyme”,also known as ADAM17/TACE, was described as "the enzyme that does it all” because of its role in neurodegenerative diseases and in several physiological processes including proteolysis, adhesion, intracellular signaling, migration and proliferation. ADAM17/TACE is an integral membrane protein that belongs to the disintegrin and metalloprotease (ADAM) family. Several years ago, Romero-Grimaldi et al.

关键词： ADAM17/TACE key molecule injury regeneration

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What we have learned and what to expect from capsule endoscopy

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World Journal of Gastrointestinal Endoscopy 2012年第10期4卷 448-452页

作者： samuel n Adler Ingvar Bjarnason Division of Gastroenterology Bikur Holim Hospital Jerusalem 95142 Israel Department of Gastroenterology King's College Hospital Denmark Hill London SE5 9RS United Kingdom

Capsule endoscopy was conceived by Gabriel Iddan and Paul Swain independently two decades ago. These applications include but are not limited to Crohn's disease of the small bowel, occult gastrointestinal bleeding, non steroidal anti inflammatory drug induced smallbowel disease, carcinoid tumors of the small bowel,gastro intestinal stromal tumors of the small bowel andother disease affecting the small bowel. Capsule endoscopy has been compared to traditional small bowelseries, computerized tomography studies and pushenteroscopy. The diagnostic yield of capsule endoscopyhas consistently been superior in the diagnosis of smallbowel disease compared to the competing methods(small bowel series, computerized tomography, pushenteroscopy) of diagnosis. For this reason capsule en-doscopy has enjoyed a meteoric success. Image qualityhas been improved with increased number of pixels,automatic light exposure adaptation and wider angle ofview. Further applications of capsule endoscopy of other areas of the digestive tract are being explored. Theincreased transmission rate of images per second hasmade capsule endoscopy of the esophagus a realisticpossibility. Technological advances that include a double imager capsule with a nearly panoramic view of the colon and a variable frame rate adjusted to the movement of the capsule in the colon have made capsuleendoscopy of the colon feasible. The diagnostic ratefor the identification of patients with polyps equal to orlarger than 6 mm is high. Future advances in technology and biotechnology will lead to further *** endoscopy is following the successful moderntrend in medicine that replaces invasive tests with lessinvasive methodology.

关键词： Capsule endoscopy Cancer screening Colon cancer Artificial intelligence Technology

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Improved DHOA-Fuzzy Based Load Scheduling in IoT Cloud Environment

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Computers, Materials & Continua 2022年第5期71卷 4101-4114页

作者： R.Joshua samuel Raj V.Ilango Prince Thomas V.R.Uma Fahd n.Al-Wesabi Radwa Marzouk Anwer Mustafa Hilal Department of Information Science&Engineering CMR Institute of TechnologyBengaluru560037India Department of Computer Application CMR Institute of TechnologyBangalore560037India School of Computing Woldia Institute of TechnologyWoldia UniversityEthiopia Department of Commerce School of CommerceFinance and AccountancyChrist UniversityBangalore560029India Department of Computer Science College of Science&Art at MahayilKing Khalid UniversitySaudi Arabia Faculty of Computer and IT Sana’a UniversityYemen Department of Information Systems College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversitySaudi Arabia Department of Computer and Self Development Preparatory Year DeanshipPrince Sattam bin Abdulaziz UniversityAlkharjSaudi Arabia

Internet of things (IoT) has been significantly raised owing to thedevelopment of broadband access network, machine learning (ML), big dataanalytics (BDA), cloud computing (CC), and so on. The development of IoTtechnologies has resulted in a massive quantity of data due to the existenceof several people linking through distinct physical components, indicatingthe status of the CC environment. In the IoT, load scheduling is realistictechnique in distinct data center to guarantee the network suitability by fallingthe computer hardware and software catastrophe and with right utilize ofresource. The ideal load balancer improves many factors of Quality of Service(QoS) like resource performance, scalability, response time, error tolerance,and efficiency. The scholar is assumed as load scheduling a vital problem inIoT environment. There are many techniques accessible to load scheduling inIoT environments. With this motivation, this paper presents an improved deerhunting optimization algorithm with Type II fuzzy logic (IDHOA-T2F) modelfor load scheduling in IoT environment. The goal of the IDHOA-T2F is todiminish the energy utilization of integrated circuit of IoT node and enhancethe load scheduling in IoT environments. The IDHOA technique is derivedby integrating the concepts of nelder Mead (nM) with the DHOA. Theproposed model also synthesized the T2L based on fuzzy logic (FL) systemsto counterbalance the load distribution. The proposed model finds usefulto improve the efficiency of IoT system. For validating the enhanced loadscheduling performance of the IDHOA-T2F technique, a series of simulationstake place to highlight the improved performance. The experimental outcomesdemonstrate the capable outcome of the IDHOA-T2F technique over therecent techniques.

关键词： Load scheduling internet of things cloud computing metaheuristics fuzzy logic

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Promoter replacement of AnT1 induces anthocyanin accumulation and triggers the shade avoidance response through developmental, physiological and metabolic reprogramming in tomato

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Horticulture Research 2023年第2期10卷 28-40页

作者： João Victor Abreu Cerqueira Feng Zhu Karoline Mendes Adriano nunes-nesi samuel Cordeiro Vitor Martins Vagner Benedito Alisdair RFernie Agustin Zsögön Departamento de Biologia Vegetal Universidade Federal de ViçosaViçosa 36570-900 MGBrazil national R&D Center for Citrus Preservation Key Laboratory of Horticultural Plant BiologyMinistry of EducationHuazhong Agricultural University430070 WuhanChina Max-Planck-Institute for Molecular Plant Physiology 14476 PotsdamGermany Division of Plant&Soil Sciences West Virginia UniversityMorgantownWV 26506USA

The accumulation of anthocyanins is a well-known response to abiotic stresses in many plant ***,the effects of anthocyanin accumulation on light absorbance and photosynthesis are ***,we addressed this question using a promoter replacement line of tomato constitutively expressing a MYB transcription factor(AnTHOCYAnIn1,AnT1)that leads to anthocyanin ***1-overexpressing plants displayed traits associated with shade avoidance response:thinner leaves,lower seed germination rate,suppressed side branching,increased chlorophyll concentration,and lower photosynthesis rates than the wild ***-rich leaves exhibited higher absorbance of light in the blue and red ends of the spectrum,while higher anthocyanin content in leaves provided photoprotection to high *** of gene expression and primary metabolites content showed that anthocyanin accumulation produces a reconfiguration of transcriptional and metabolic networks that is consistent with,but not identical to those described for the shade avoidance *** results provide novel insights about howanthocyanins accumulation affects the trade-off between photoprotection and growth.

关键词： metabolic expressing programming

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Tracheal relaxation of five medicinal plants used in Mexico for the treatment of several diseases

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Asian Pacific Journal of Tropical Medicine 2014年第3期7卷 179-183页

作者： Amanda Snchez-Recillas Paul Mantecón-Reyes Patricia Castillo-Espaa Rafael Villalobos-Molina Maximiliano Ibarra-Barajas samuel Estrada-Soto Facultad de Farmacia Universidad Autonoma del Estado de MorelosAvenida Universidad 1001.Col.ChamilpaCuernavacaMorelos 62209México Centro de Investigación en Riotecnología Universidad Autónoma del Estado de Morelos.Avenida Universidad 1001Col.ChamilpaCuernavacaMorelos 62209México Unidad de Biomedicina Facultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantlaEstudo de Mexico 54090México

Objective:To assess the relaxant effect of several organic extracts obtained from Agastache mexicana(***),Cochlospermum vitifolium(***),Cordia morelosana(***),Lepechinia caulescens(***)and Talauma mexicana(71 mexicana)used in Mexican traditional medicine for the treatment of several ***:Extracts were obtained by maceration at room temperature using hexane,dicliloromethane and methanol for each plant *** organic extracts were evaluated ex vivo to determine their relaxant activity on the contractions induced by carbaehol(cholinergic receptor agonist,1μmol/L in isolated rat tracheal ***:A total of 15 extracts were evaluated(three for each species).All test samples showed significant relaxant effect,in a concentration-dependent manner,on the contractions induced by 1μmol/L carbachol,with exception of extracts from *** extracts were less potent than theophylline[phosphodiesterase inhibitor,EC_(50):(28.79±0.82)μg/mL]that was used as positive ***-response curves revealed that the extracts with more significant effects were dichloromethanic extracts of ***[E_(max):(103.03±3.32)%and EC_(50):(159.39±3.72)μg/mL)and ***[Emax:(106.58±2.42)%and EC_(50):(219.54±7.61)μg/mL].Finally,hexanic and dichloromethanic extracts from *** were fully effective but less potent than ***,and ***:Less polar extracts obtained from ***,71 mexicana and *** exhibited greater relaxant effect on tracheal rat rings,which allows us to suggest them as sources for the isolation of bioactive molecules with potential therapeutic value in the treatment of asthma.

关键词： Asthma Mexican medicinal plants Trachea Relaxant effect

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Model based current mode control design and experimental validation for a 3φ rectifier under unbalanced grid voltage conditions

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Journal of Modern Power Systems and Clean Energy 2018年第4期6卷 777-790页

作者： P.R.MARTínEZ-RODRIGEZ Jose M.SOSA samuel ITURRIAGA-MEDInA Gerardo ESCOBAR Gerardo VáZQUEZ-GUZMán Andres A.VALDEZ-FERnánDEZ School of Sciencies UASLP Laboratory of Electrical and Power Electronics ITESI School of Engineering Universidad Modelo

This paper addresses the control design and the experimental validation of a current mode control for a three phase voltage source rectifier. The proposed control law is able to fulfill the voltage regulation and the current tracking control objectives despite of unbalanced and distorted grid voltages. The proposed control law consists of two loops, which are referred as inner tracking loop and the outer voltage regulation loop. The inner loop is designed to provide damping to the system, which also includes and adaptive mechanism. The construction of the current reference is based on the positive component detection of thegrid voltage. Therefore, the current produced by the power rectifier is proportional to the fundamental component of the grid voltage, despite of the presence of unbalanced grid voltages. The voltage regulation loop is designed as a proportional-integral controller, which is aimed to regulate the DC output voltage to a desired level. Finally, experimental results are obtained in an experimental prototype of2 kW to evaluate the performance of the proposed controller.

关键词： Pulse-width modulation rectifier Power factor correction Positive-component Current mode control

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Automated classification of big X-ray diffraction data using deep learning models

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npj Computational Materials 2023年第1期9卷 169-180页

作者： Jerardo E.Salgado samuel Lerman Zhaotong Du Chenliang Xu niaz Abdolrahim Materials Science program University of RochesterRochesterNew York 14627USA Department of Computer Science University of RochesterRochesterNew York 14627USA Department of Mechanical Engineering University of RochesterRochesterNew York 14627USA Laboratory for Laser Energetics University of RochesterRochesterNew York 14627USA

In current in situ X-ray diffraction(XRD)techniques,data generation surpasses human analytical capabilities,potentially leading to the loss of *** techniques require human intervention,and lack the performance and adaptability required for material *** the critical need for high-throughput automated XRD pattern analysis,we present a generalized deep learning model to classify a diverse set of materials’crystal systems and space *** our approach,we generate training data with a holistic representation of patterns that emerge from varying experimental conditions and crystal *** also employ an expedited learning technique to refine our model’s expertise to experimental *** addition,we optimize model architecture to elicit classification based on Bragg’s Law and use evaluation data to interpret our model’s *** evaluate our models using experimental data,materials unseen in training,and altered cubic crystals,where we observe state-of-the-art performance and even greater advances in space group classification.

关键词： Automate classify cubic

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Experimental investigation of gaseous solvent huff-n-puff in the Middle Bakken Formation

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Petroleum Science 2023年第6期20卷 3488-3497页

作者： samuel Asante Afari Kegang Ling Demetrius Maxey Billel Sennaoui Jerjes Hurtado Porlles Department of Petroleum Engineering University of North Dakota2844 Campus RdStop 8154Grand ForksND58202-6116USA

The efficacy of gaseous solvents in enhancing oil recovery(EOR)in unconventional reservoirs and the influence of operational and design parameters are still debated among the oil recovery research *** work investigated the recovery-enhancing capabilities of two potent gaseous solvents,CO_(2) and ethane,in tight core *** huff-n-puff(H-n-P)experiments were conducted under three miscibility conditions to investigate the influence of the key operating parameters and the dependency of their impact on the miscibility conditions and gas *** results show that oil recovery increased with increasing pressure from below(BM)to above(AM)miscibility pressure in a non-linear trend,irrespective of the gas ***,the influence of the soak period was noticeably dependent on the miscibility condition,specifically more remarkable under AM conditions and less apparent under BM ***,the effect of the production period was more pronounced at AM conditions for both ***,the impact of rock surface area-to-volume(SA/V)was only observed at BM,where both gases recovered more oil in the core samples with high SA/*** general,ethane showed a higher efficacy for oil recovery than CO_(2);CO_(2) recovered 21%–70%of oil in small core samples,while ethane could recover 32%–88%.The highest recovery was achieved with ethane injected under AM conditions,with a prolonged soak time,a short production period and into a core sample with a high SA/*** believe the findings from this work will help better understand and design H-n-P EOR projects.

关键词： Unconventional reservoirs Huff-n-puff Gas solvent Ethane CO_(2)miscibility

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